Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Chronic idiopathic inflammatory bowel diseases of the horse
Publication Year: 2000 Source: J Vet Intern Med PMID: 10830538 DOI: 10.1892/0891-6640(2000)014<0258:ciibdo>2.3.co;2
Not found
Replenishment of glutathione levels improves mucosal function in experimental acute colitis
Publication Year: 2000 Source: Lab Invest PMID: 10830784 DOI: 10.1038/labinvest.3780077
Tumor necrosis factor alpha (TNFalpha)-stimulated nuclear factor (NF) kappaB activation plays a key role in the pathogenesis of inflammatory bowel disease (IBD). Phosphorylation of NFkappaB inhibitory protein (IkappaB) leading to its degradation and NFkappaB activation, is regulated by the multimeric IkappaB kinase complex, including IKKalpha and IKKbeta. We recently reported …
Analysis of a positional candidate gene for inflammatory bowel disease: NRAMP2
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10833067 DOI: 10.1097/00054725-200005000-00004
IL-15 shares biological activities but no significant sequence homology with IL-2. It induces T cell recruitment to sites of inflammation, T cell proliferation, and cytokine production and rescue from apoptosis. The aim of this study was to investigate expression of IL-15 and its effects on proinflammatory cytokine production in inflammatory …
Evaluation of IBD candidate genes and the case of NRAMP2
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10833068 DOI: 10.1097/00054725-200005000-00005
BACKGROUND & AIMS: The ability to identify children with CD who are at highest risk for rapid progression from uncomplicated to complicated phenotypes would be invaluable in guiding initial therapy. The aims of this study were to determine whether immune responses and/or CARD15 variants are associated with complicated disease phenotypes …
Absence of GNAI2 codon 179 oncogene mutations in inflammatory bowel disease
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10833069 DOI: 10.1097/00054725-200005000-00006
OBJECTIVE: CD4 lymphocytes mediate disease expression in both human immunodeficiency virus (HIV) infection and inflammatory bowel disease (IBD). Analysis of the clinical course of IBD in HIV-seropositive individuals may elucidate aspects of the role of CD4 lymphocytes in the pathogenesis of these conditions. DESIGN: A retrospective case series study. PATIENTS: …
Probiotics and inflammatory bowel disease: is there a scientific rationale?
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10833070 DOI: 10.1097/00054725-200005000-00007
For many complex diseases, study has suggested that the disease genes influence not only the occurrence of the disease, but also the age of onset. Current methods in linkage analysis are mainly concentrated on affected relative pairs or affected family members, and age of onset information is either ignored or …
Anemia in IBD: the overlooked villain
Publication Year: 2000 Source: Inflamm Bowel Dis PMID: 10833075 DOI: 10.1097/00054725-200005000-00013
This article provides an in-depth review of the radiologic and endoscopic imaging techniques used in the evaluation and management of inflammatory bowel disease (IBD). The use of imaging studies to diagnose IBD and to differentiate ulcerative colitis from Crohn's disease is discussed. The evaluation of suspected complications associated with IBD, …
Decreased trabecular bone mineral density in newly diagnosed inflammatory bowel disease patients in Korea
Publication Year: 2000 Source: J Gastroenterol Hepatol PMID: 10847438 DOI: 10.1046/j.1440-1746.2000.02154.x
CD and UC represent a spectrum of chronic IBD that present in protean ways and are accompanied by a variety of systemic sequelae. Sulfasalazine and the newer 5-aminosalicylates are important in the management of mild-to-moderate disease, whereas corticosteroids remain the primary therapy for most patients with moderate-to-severe disease (Tables 2-5). …
Liver transplantation for primary sclerosing cholangitis
Publication Year: 2000 Source: Liver PMID: 10847476 DOI: 10.1034/j.1600-0676.2000.020002097.x
Two-stage global search designs for linkage analysis using pairs of affected relatives were shown by Elston et al. [1996] to typically halve the cost of a study compared to a one-stage design. The statistic used for testing linkage in that study was based on the proportion of pairs sharing no …
Immunoglobulin G and albumin levels in whole gut lavage fluid provide an objective measure of pouch ileitis
Publication Year: 2000 Source: Br J Surg PMID: 10848863 DOI: 10.1046/j.1365-2168.2000.01424.x
The advent of advanced molecular biological techniques in the last two decades has allowed the study of genetic factors in inflammatory bowel disease (IBD). A variety of techniques have been employed to elucidate the effects of genes, starting with the clinical observations that IBD is more common in the relatives …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide