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Clinical features and treatment of peristomal pyoderma gangrenosum

Publication Year: 2000 Source: JAMA PMID: 11000649 DOI: 10.1001/jama.284.12.1546

Not found

Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with IBD

Publication Year: 2000 Source: Gut PMID: 11001654 DOI: 10.1136/gut.47.3.456

Not found

Evaluation of the effectiveness of a specialist nurse in the management of inflammatory bowel disease (IBD)

Publication Year: 2000 Source: Eur J Gastroenterol Hepatol PMID: 11007131 DOI: 10.1097/00042737-200012090-00001

Comment in Eur J Gastroenterol Hepatol. 2000 Jul;12(7):821-2. BACKGROUND: A thrombotic aetiology for inflammatory bowel disease (IBD) has been proposed as a result of its association with thrombo-embolic complications, smoking, the oral contraceptive pill and the response of ulcerative colitis (UC) patients to heparin. The factor V Leiden (FVL) mutation …

Passive smoking in patients with inflammatory bowel disease: an Israeli multicentre case-control study

Publication Year: 2000 Source: Eur J Gastroenterol Hepatol PMID: 11007132 DOI: 10.1097/00042737-200012090-00002

We set out to examine if the IgG-producing cells in the colonic mucosa in UC are committed to tropomyosin isoform 5 (hTM5), a putative autoantigen in UC. Lamina propria mononuclear cells (LPMC) were isolated from colonoscopic biopsy specimens from recto-sigmoid and proximal colon. Twenty-three patients with UC, eight with Crohn's …

Enterocolitis in children with developmental disorders

Publication Year: 2000 Source: Am J Gastroenterol PMID: 11007230 DOI: 10.1111/j.1572-0241.2000.03248.x

OBJECTIVE: Rheumatoid arthritis (RA) is the most common disabling autoimmune disease, affecting approximately 1% of the population. The disease etiology is unknown, but it involves inflammation and immune dysregulation and is influenced by genetic variation at both HLA and other, as-yet-unidentified genetic loci. Corticotropin-releasing hormone (CRH; or corticotropin-releasing factor), a …

6MP for fathers with IBD at the time of conception: the value of a large clinical experience over unrelated controls

Publication Year: 2000 Source: Am J Gastroenterol PMID: 11007251 DOI: 10.1111/j.1572-0241.2000.02341.x

Not found

Pitfalls in homozygosity mapping

Publication Year: 2000 Source: Am J Hum Genet PMID: 11007652 DOI: 10.1016/S0002-9297(07)62966-8

In order to determine genetic relatedness of Bacteroides fragilis isolates from different clinical sources, arbitrarily primed polymerase chain reaction (PCR) (AP-PCR) was used to compare 17 strains isolated from patients with inflammatory bowel disease (IBD) and 20 strains isolated from foals with diarrhea. Three reference ATCC strains were also analyzed. …

The role of aminosalicylates at the beginning of the new millennium in the treatment of chronic inflammatory bowel disease

Publication Year: 2000 Source: Eur J Clin Pharmacol PMID: 11009042 DOI: 10.1007/s002280000163

BACKGROUND: The vitamin D receptor (VDR) gene represents a strong positional candidate susceptibility gene for inflammatory bowel disease (IBD). The VDR gene maps to a region on chromosome 12 that has been shown to be linked to IBD by genome screening techniques. It is the cellular receptor for 1,25(OH)(2) vitamin …

Laboratory findings associated with thrombophilia are not more common in inflammatory bowel disease

Publication Year: 2000 Source: Clin Lab Haematol PMID: 11012640 DOI: 10.1046/j.1365-2257.2000.00119.x

Not found

Transforming growth factor-alpha and epidermal growth factor receptor in colonic mucosa in active and inactive inflammatory bowel disease

Publication Year: 2000 Source: Growth Factors PMID: 11019780 DOI: 10.3109/08977190009003235

German shepherd dogs (GSD) are predisposed to enteropathies such as inflammatory bowel disease (IBD) and small intestinal bacterial overgrowth (SIBO). The present study examined the role of cytokines in the immunopathogenesis of both conditions. Duodenal mucosal biopsies were taken from GSDs with small intestinal enteropathies (group 1; N = 16) …

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