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Comparative tolerability of treatments for inflammatory bowel disease
Publication Year: 2000 Source: Drug Saf PMID: 11085348 DOI: 10.2165/00002018-200023050-00006
Not found
The incidence of fracture among patients with inflammatory bowel disease. A population-based cohort study
Publication Year: 2000 Source: Ann Intern Med PMID: 11085842 DOI: 10.7326/0003-4819-133-10-200011210-00012
BACKGROUND & AIMS: Atypical "antineutrophil cytoplasmic antibodies" (ANCA) are present in patients with ulcerative colitis (UC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH). Recently, we showed that atypical p-ANCA react with nuclear envelope proteins of neutrophils. Based on this observation, we aimed to characterize the nuclear antigen recognized by …
Occurrence of IgA and IgG autoantibodies to calreticulin in coeliac disease and various autoimmune diseases
Publication Year: 2000 Source: J Autoimmun PMID: 11090243 DOI: 10.1006/jaut.2000.0452
Intestinal lamina propria T lymphocytes (LP-Ts) have a markedly low proliferative potential both in vivo and in vitro. Here, we have identified that the capacity of antigen-presenting cells to release cysteine upon receptor-ligand interactions represents a critical parameter for proliferation of LP-Ts. The availability of cysteine is limiting for the …
Ultrasensitive and specific detection methods for exocylic DNA adducts: markers for lipid peroxidation and oxidative stress
Publication Year: 2000 Source: Toxicology PMID: 11090950 DOI: 10.1016/s0300-483x(00)00307-3
Comment in Am J Gastroenterol. 2000 Apr;95(4):861. OBJECTIVE: Inflammatory bowel diseases (IBD) are immune-mediated disorders wherein an imbalance between proinflammatory (Th1) and antiinflammatory (Th2) cytokines is thought to play a role in the pathogenesis. The aim of this study was to test whether induction of oral tolerance to proteins extracted …
Combined segregation and linkage analysis of inflammatory bowel disease in the IBD1 region using severity to characterise Crohn's disease and ulcerative colitis. On behalf of the GISC
Publication Year: 2000 Source: Eur J Hum Genet PMID: 11093274 DOI: 10.1038/sj.ejhg.5200542
OBJECTIVE: The finding of colonic inflammation concurrently with a juvenile retention polyp (JRP) may have prognostic value. However, the significance of abnormal mucosal histology with JRP has not been evaluated. We evaluated the significance of mucosal histology at the time of JRP removal with respect to future development of inflammatory …
The relationship between heritability and smoking habits in Crohn's disease. Italian Cooperative Study Group
Publication Year: 2000 Source: Am J Gastroenterol PMID: 11095337 DOI: 10.1111/j.1572-0241.2000.03196.x
Thromboembolic disease (TED) has been recognized as a complication of inflammatory bowel disease (IBD) since the 1930s (Bargen & Barker 1936). The relative contributions of inherited or acquired thrombophilia and the inflammatory response to the mechanism of this tendency is unclear. Thrombotic events are more common in active disease although …
The importance of diagnostic accuracy in colonic inflammatory bowel disease
Publication Year: 2000 Source: Am J Gastroenterol PMID: 11095339 DOI: 10.1111/j.1572-0241.2000.03199.x
OBJECTIVE: Delayed perineal wound healing following 'conventional' excision of the rectum for IBD is common-up to 58% in patients with ulcerative colitis (UC) and 72% in those with Crohn's disease (CD) 6 months following proctectomy. The risk of perineal wound morbidity is increased if anorectal sepsis is present at the …
Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis
Publication Year: 2000 Source: Am J Gastroenterol PMID: 11095341 DOI: 10.1111/j.1572-0241.2000.03292.x
Tissue and plasma concentrations of several cytokines are increased in patients with inflammatory bowel disease (IBD). Platelets play an important role in inflammation and circulate in an activated state in patients with IBD. This study assesses the expression of IL-8 and IL-1 receptors on the surface of platelets from patients …
Pediatric Inflammatory Bowel Disease
Publication Year: 2000 Source: Curr Treat Options Gastroenterol PMID: 11096601 DOI: 10.1007/s11938-000-0055-2
Not found
The dietary combination of germinated barley foodstuff plus Clostridium butyricum suppresses the dextran sulfate sodium-induced experimental colitis in rats
Publication Year: 2000 Source: Scand J Gastroenterol PMID: 11099059 DOI: 10.1080/003655200451180
Not found
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