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The VP2 variable region of African and German isolates of infectious bursal disease virus: comparison with very virulent, "classical" virulent, and attenuated tissue culture-adapted strains

Publication Year: 2000 Source: Arch Virol PMID: 10664410 DOI: 10.1007/s007050050009

Not found

Altered bone metabolism in inflammatory bowel disease: there is a difference between Crohn's disease and ulcerative colitis

Publication Year: 2000 Source: J Intern Med PMID: 10672132 DOI: 10.1046/j.1365-2796.2000.00582.x

To determine whether the first presenting symptoms, the main problem that the disease is causing to patients, and the employment status at presentation of patients with early spondyloarthritis (SpA) in a multicultural/multiracial patient cohort are different between gender, race, and disease subgroups of the SpA spectrum (ankylosing spondylitis, enteropathic arthritis, …

Relationship between intestinal permeability and calprotectin concentration in gut lavage fluid

Publication Year: 2000 Source: Scand J Gastroenterol PMID: 10672837 DOI: 10.1080/003655200750024551

Not found

Interleukin 10 gene transfer prevents experimental colitis in rats

Publication Year: 2000 Source: Gut PMID: 10673295 DOI: 10.1136/gut.46.3.344

OBJECTIVE: To study the concordance between abdominal scintigraphy using technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO)-labelled leucocytes (ASTLL) and ileocolonoscopy in patients with spondyloarthropathies (SpA) and without clinical evidence of inflammatory bowel disease (IBD). PATIENTS AND METHODS: Fifteen patients with SpA (European Spondylarthropathy Study Group 1991 criteria) without clinical evidence of IBD …

Effects of stratification in the analysis of affected-sib-pair data: benefits and costs

Publication Year: 2000 Source: Am J Hum Genet PMID: 10677317 DOI: 10.1086/302748

In intestinal bowel disease (IBD), immune-mediated conditions exert their effects through various cells and proinflammatory mediators. Recent data support a participation of the endoplasmic reticulum stress and mitochondrial dysfunctions in IBD. Moreover, it is evident that chronic degenerative pathologies, including IBD, share comparable disease mechanisms with alteration in the autophagy …

Clinical and radiological characteristics of lung disease in inflammatory bowel disease

Publication Year: 2000 Source: Eur Respir J PMID: 10678619 DOI: 10.1183/09031936.00.15104100

Comment in Am J Gastroenterol. 1999 Dec;94(12):3396-8. OBJECTIVES: The aims of this study were: 1) to examine whether the fecal levels of eosinophil granule-derived proteins reflect disease activity in inflammatory bowel disease (IBD); and 2) to examine the extracellular release of these proteins from eosinophils and their stability in feces …

An immunohistochemical study of histiocytic ulcerative colitis in boxer dogs

Publication Year: 2000 Source: J Comp Pathol PMID: 10684685 DOI: 10.1053/jcpa.1999.0353

Comment in Gut. 2001 Jan;48(1):136-7. BACKGROUND: Measles virus is implicated in the aetiology of Crohn's disease. This measles hypothesis is mainly supported by immunohistochemical findings that the measles related antigen is present in the intestine of patients with Crohn's disease. Recently we isolated this antigen from the intestine of a …

Established and emerging biological activity markers of inflammatory bowel disease

Publication Year: 2000 Source: Am J Gastroenterol PMID: 10685736 DOI: 10.1111/j.1572-0241.2000.t01-1-01790.x

AIMS: Overexpression of CD44v6 in colon crypt epithelial cells has been suggested to have diagnostic potential in differentiating ulcerative colitis from other forms of colon inflammation, including Crohn's disease. Our aim was to determine the value of CD44v6 expression in inflammatory bowel disease (IBD) and to look for possible associations …

Lack of association between smoking and Crohn's disease but the usual association with ulcerative colitis in Jewish patients in Israel: a multicenter study

Publication Year: 2000 Source: Am J Gastroenterol PMID: 10685753 DOI: 10.1111/j.1572-0241.2000.01771.x

Comment in Eur J Gastroenterol Hepatol. 1998 Mar;10(3):235-7. OBJECTIVE: The rising incidence of inflammatory bowel disease (IBD) since the Second World War coincides with profound changes of the dietary pattern. The aim of the study was to investigate the possible pathogenic role of some characteristic 'modern life' dietary factors in …

HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) and non-Jewish caucasian populations

Publication Year: 2000 Source: Hum Immunol PMID: 10689124 DOI: 10.1016/s0198-8859(99)00134-2

The risk of developing colorectal cancer is increased in patients with inflammatory bowel disease (IBD). Surveillance colonoscopy has not been shown to prolong survival and rates of interval cancer are reported to be high. Various chemopreventive agents have been clearly shown to reduce the risk of colorectal adenoma and cancer …

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