Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Synergistic effects of interferon gamma and tumour necrosis factor alpha on T84 cell function
Publication Year: 1999 Source: Gut PMID: 10403730 DOI: 10.1136/gut.45.2.191
Not found
pH regulation of K(+) efflux from myocytes in isolated rat hearts: (87)Rb, (7)Li, and (31)P NMR studies
Publication Year: 1999 Source: Am J Physiol PMID: 10409207 DOI: 10.1152/ajpheart.1999.277.1.H279
Not found
Detecting QTLs for uni- and bipolar disorder using a variance component method
Publication Year: 1999 Source: Psychiatr Genet PMID: 10412186 DOI: 10.1097/00041444-199906000-00005
Not found
A genomic screen of autism: evidence for a multilocus etiology
Publication Year: 1999 Source: Am J Hum Genet PMID: 10417292 DOI: 10.1086/302497
BACKGROUND: Vascular endothelial E-selectin expression is induced by proinflammatory cytokines and contributes to accumulation of leucocytes in tissues. AIMS: To investigate the role of E-selectin in inflammatory bowel disease (IBD). METHODS: E-selectin expression was assessed in patients with ulcerative colitis and Crohn's disease by measuring the concentration of circulating soluble …
Effect of substance P on histamine secretion from gut mucosa in inflammatory bowel disease
Publication Year: 1999 Source: Scand J Gastroenterol PMID: 10423066 DOI: 10.1080/003655299750026236
Inflammatory bowel disease (IBD) is a generic term typically used to describe a group of idiopathic inflammatory intestinal conditions in humans that are generally divided into Crohn's disease and ulcerative colitis. Although the etiology of these diseases remains unknown, a number of rodent models of IBD have recently been identified, …
Novel Salmonella typhimurium properties in host--parasite interactions
Publication Year: 1999 Source: Immunol Lett PMID: 10424427 DOI: 10.1016/s0165-2478(99)00073-5
Scid mice transplanted with low numbers of syngeneic CD4+ T cells, develop a chronic and lethal inflammatory bowel disease (IBD) within 4-6 months. We have used in vivo 5-bromo2-deoxy-uridine (BrdU) labeling to assess the proliferation of lamina propria-derived CD4+ T cells in diseased scid mice. The hourly rate of renewal …
Pediatric inflammatory bowel disease: assessment with scintigraphy with 99mTc white blood cells
Publication Year: 1999 Source: Radiology PMID: 10429710 DOI: 10.1148/radiology.212.2.r99au45507
Cytosolic phospholipase A2 (PLase A2) is activated by low Ca2+ concentrations and translocates from the cytosol to the cell membrane, releasing arachidonic acid; the arachidonic acid cascade then leads to the production of many inflammatory mediators. The aim of this study, accordingly, was to investigate the role of phospholipid metabolism …
Multipoint linkage analysis. A cautionary note
Publication Year: 1999 Source: Hum Hered PMID: 10436380 DOI: 10.1159/000022874
Serum tumor necrosis factor (TNF) levels in 33 patients with inflammatory bowel disease (IBD) were measured by using a sensitive enzyme immunoassay. Four of five Crohn's diseases (CD) and nine of twenty eight ulcerative colitis (UC) had elevated levels of serum TNF. In active CD or UC, a greater fraction …
Differences in P-glycoprotein-170 expression and activity between Crohn's disease and ulcerative colitis
Publication Year: 1999 Source: Hum Immunol PMID: 10439313 DOI: 10.1016/s0198-8859(99)00036-1
OBJECTIVES: A multicenter double-blind placebo-controlled clinical study was conducted to evaluate the efficacy and tolerability of two different therapeutic schedules of mesalazine suppositories in patients with ulcerative proctitis. METHODS: From 1990 to 1993, 111 patients with ulcerative proctisis in remission, limited to the rectum (< or = 15 cm from …
Genetic analysis in Italian families with inflammatory bowel disease supports linkage to the IBD1 locus--a GISC study
Publication Year: 1999 Source: Eur J Hum Genet PMID: 10439963 DOI: 10.1038/sj.ejhg.5200328
The majority of patients with IBD use conventional therapy (namely, aminosalicylates, antibiotics, corticosteroids and immunomodulatory agents) for prolonged periods of time, to both induce and maintain remission. Treatment paradigms in IBD have evolved towards a rapid escalation of therapy to achieve stringent goals, including mucosal healing and a reduction in …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide