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More evidence of the failure of oral cyclosporine to maintain remission due to intravenous cyclosporine in IBD

Publication Year: 1999 Source: J Clin Gastroenterol PMID: 10478868 DOI: 10.1097/00004836-199909000-00002

Not found

Cyclosporine therapy in inflammatory bowel disease: short-term and long-term results

Publication Year: 1999 Source: J Clin Gastroenterol PMID: 10478875 DOI: 10.1097/00004836-199909000-00009

OBJECTIVES: Immunologic studies have characterized the numbers and types of inflammatory cells in diseased inflammatory bowel disease (IBD) mucosa but have yielded conflicting results regarding intestinal lymphocytes activation in IBD. We investigated the levels of lymphocytes subsets, interleukin-2 receptor, transferrin receptor, and T cell receptors in mainly isolated lamina propria …

Lymphocyte apoptosis in systemic lupus erythematosus: relationships with Fas expression, serum soluble Fas and disease activity

Publication Year: 1999 Source: Lupus PMID: 10483027 DOI: 10.1191/096120399678840765

BACKGROUND: In spite of the accumulating evidence of an increased prevalence of osteopenia and osteoporosis in patients with inflammatory bowel diseases (IBD), the time course of bone loss is not well described, and there is little knowledge about factors indicating an increased risk of rapid bone loss. METHODS: We conducted …

Cytokines and inflammatory bowel disease: a review

Publication Year: 1999 Source: JPEN J Parenter Enteral Nutr PMID: 10483888 DOI: 10.1177/014860719902300506

Not found

Effect of DA-6034, a derivative of flavonoid, on experimental animal models of inflammatory bowel disease

Publication Year: 1999 Source: Arch Pharm Res PMID: 10489873 DOI: 10.1007/BF02979057

Comment in Gut. 1997 Dec;41(6):859-60. BACKGROUND: Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel diseases (IBD) involving synthesis of eicosanoids from arachidonic acid (AA), which is released from membrane phospholipids by phospholipase A2 (PLA2). A potentially important regulator of the production of these mediators is a protein activator of …

Bombesin ameliorates colonic damage in experimental colitis

Publication Year: 1999 Source: Dig Dis Sci PMID: 10492129 DOI: 10.1023/a:1026646523284

Not found

Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children

Publication Year: 1999 Source: Dig Dis Sci PMID: 10492133 DOI: 10.1023/a:1026654725101

It has been reported that in patients with inflammatory bowel disease (IBD), the airways are involved, and a number of clinical manifestations have been described. The aim of this study was to investigate the function of the small airways in IBD. Thirty patients with IBD (mean age, 47 yr), 12 …

Nutrition and inflammatory bowel disease: an update

Publication Year: 1999 Source: Scand J Gastroenterol Suppl PMID: 10499469 DOI: 10.1080/003655299750025615

Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is associated with an increased risk of osteoporosis and bone fractures. Initial studies suggested very high rates of osteoporosis in IBD, but more recent studies have suggested that bone mineral density (BMD) is often normal in patients with IBD and …

Faecal parameters in the assessment of activity in inflammatory bowel disease

Publication Year: 1999 Source: Scand J Gastroenterol Suppl PMID: 10499470 DOI: 10.1080/003655299750025624

Epidemiological studies suggest that inherited factors influence susceptibility to inflammatory bowel disease (IBD), and some candidate loci have been described. In order to verify whether the same loci are responsible for predisposition to IBD in our population, we carried out a linkage study in a series of 58 Italian families …

Ultrasound measurements of calcaneus for estimation of skeletal status in patients with inflammatory bowel disease

Publication Year: 1999 Source: Scand J Gastroenterol PMID: 10499480 DOI: 10.1080/003655299750025723

Experimental data indicate that mucosal CD4+ T cells play an important role in the pathogenesis of inflammatory bowel disease (IBD). Based on the pattern of cytokine production, CD4+ T cells may be distinguished into two different phenotypes. Th1 responses are characterized by secretion of interleukin (IL)-2, tumor necrosis factor (TNF)-alpha, …

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