|
FBPs
|
fbp54
|
0.0355483 |
124 |
VF0243
|
Adherence |
(fbp54) fibronectin-bing protein Fbp54 [FBPs (VF0243) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS6180]
|
|
Ent
|
entF
|
0.0002734 |
1 |
VF0562
|
Nutritional/Metabolic factor |
(entF) enterobactin synthase subunit F [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LOS
|
galE
|
0.1903199 |
694 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
Capsule
|
cap8F
|
0.005469 |
16 |
VF0003
|
Immune modulation |
(cap8J) type 8 capsular polysaccharide synthesis protein Cap8J [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Hyaluronic acid capsule
|
hasB
|
1.034181 |
3,655 |
VF0244
|
Immune modulation |
(hasB) UDP-glucose 6-dehydrogenase HasB [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
CNA
|
cna
|
0.0005469 |
2 |
VF0005
|
Adherence |
(cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SodB
|
sodB
|
0.0002734 |
1 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Lap
|
lap
|
0.0062893 |
19 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
glf
|
0.0060159 |
21 |
VF0323
|
Immune modulation |
(glf) UDP-galactopyranose mutase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Hyaluronidase
|
hylA
|
0.0002734 |
1 |
VF0246
|
Exoenzyme |
(hylA) hyaluronidase [Hyaluronidase (VF0246) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
Type VII secretion system
|
essC
|
0.0429314 |
104 |
VF0403
|
Effector delivery system |
(essC) type VII secretion system protein EssC, FtsK/SpoIIIE family ATPase [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
AcrAB
|
acrB
|
0.0002734 |
1 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
VirB/VirD4 type IV secretion system
|
virB4
|
0.0002734 |
1 |
VF0369
|
Effector delivery system |
(virB4) type IV secretion system virB4 protein homolog [VirB/VirD4 type IV secretion system (VF0369) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
FbsB
|
fbsB
|
0.0005469 |
2 |
VF0523
|
Adherence |
(fbsB) Fibrinogen-binding surface protein B [FbsB (VF0523) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
SpaP
|
spaP/pac
|
0.0013672 |
5 |
VF0526
|
Adherence |
(spaP/pac) cell surface antigen SpaP [SpaP (VF0526) - Adherence (VFC0001)] [Streptococcus mutans UA159]
|
|
T6SS
|
vipB/tssC
|
0.0005469 |
2 |
VF0569
|
Effector delivery system |
(vipB/tssC) type VI secretion system contractile sheath large subunit VipB [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
ECP
|
ykgK/ecpR
|
0.0002734 |
1 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
PI-2a
|
pilB
|
0.0095707 |
34 |
VF0528
|
Adherence |
(pilB) major subunit PilB [PI-2a (VF0528) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
RlrA islet
|
srtC-2/srtC
|
0.372163 |
1,352 |
VF0529
|
Adherence |
(srtC-1/srtB) sortase [RlrA islet (VF0529) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
FeoAB
|
feoB
|
0.0010938 |
4 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Type IV pili
|
rpoS
|
0.0002734 |
1 |
VF0082
|
Adherence |
(rpoS) RNA polymerase sigma factor RpoS [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
PavA
|
pavA
|
0.9745693 |
3,550 |
VF0283
|
Adherence |
(pavA) Fibronectin-binding protein-like protein A [PavA (VF0283) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
|
|
Capsule
|
ugd
|
1.0125786 |
3,654 |
VF0560
|
Immune modulation |
(gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
cpsB/cdsA
|
1.2430954 |
3,594 |
VF0361
|
Immune modulation |
(cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
AS
|
EF0149
|
0.0005469 |
2 |
VF0352
|
Adherence |
(EF0149) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Lmb
|
lmb
|
0.0021876 |
6 |
VF0275
|
Adherence |
(lmb) laminin-binding surface protein [Lmb (VF0275) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
Polar flagella
|
flmH
|
0.0008203 |
3 |
VF0473
|
Motility |
(flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
FupA
|
feoB
|
0.0002734 |
1 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
GroEL
|
groEL
|
1.0123052 |
3,654 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
C5a peptidase
|
scpA/scpB
|
0.0005469 |
2 |
VF0278
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0278) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
Hsp60
|
htpB
|
0.0002734 |
1 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Beta-haemolysin/cytolysin
|
cylZ
|
0.0005469 |
2 |
VF0279
|
Exotoxin |
(cylG) 3-ketoacyl-ACP-reductase CylG [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0041017 |
14 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
ClpC
|
clpC
|
0.0019141 |
7 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
1.0057424 |
3,652 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
O-antigen
|
galE
|
0.0016407 |
6 |
VF0392
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
ClpE
|
clpE
|
0.0076565 |
27 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
neuA
|
0.5928357 |
1,650 |
VF0274
|
Immune modulation |
(GBS_RS06585) UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase [Capsule (VF0274) - Immune modulation (VFC0258)] [Streptococcus agalactiae NEM316]
|
|
PNAG
|
pgaC
|
0.0002734 |
1 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Flagella
|
flhA
|
0.0002734 |
1 |
VF0273
|
Motility |
(flhA) flagellar biosynthesis protein FlhA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
Flagella
|
motB
|
0.0010938 |
4 |
VF0394
|
Motility |
(motB) flagellar motor protein MotB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
PmrAB
|
pmrA
|
0.0002734 |
1 |
VF1355
|
Regulation |
(pmrA) response regulator PmrA [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
cps4E
|
1.8066721 |
3,516 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Autolysin
|
cbpD
|
0.0005469 |
2 |
VF0143
|
Exoenzyme |
(cbpD) choline binding protein D [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
P fimbriae
|
papD
|
0.0002734 |
1 |
VF0220
|
Adherence |
(papD) chaperone protein PapD [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
LPS
|
wbtM
|
1.2378999 |
3,656 |
VF0542
|
Immune modulation |
(wbtM) dTDP-D-glucose 4,6-dehydratase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Hyaluronidase
|
hysA
|
0.0005469 |
2 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
TTSS secreted effectors
|
espR1
|
0.0008203 |
1 |
VF1111
|
Effector delivery system |
(espX5) Type III secretion system effector EspX5 [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
Type 1 fimbriae
|
fimZ
|
0.0002734 |
1 |
VF0102
|
Adherence |
(fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
galE
|
0.0016407 |
6 |
VF0465
|
Immune modulation |
(ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Neuraminidase
|
nanB
|
0.026251 |
92 |
VF0148
|
Exoenzyme |
(nanB) neuraminidase B [Neuraminidase (VF0148) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
Alpha-Hemolysin
|
hlyD
|
0.0002734 |
1 |
VF0225
|
Exotoxin |
(hlyD) Hemolysin D [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Nitrate reductase
|
narH
|
0.0002734 |
1 |
VF0302
|
Nutritional/Metabolic factor |
(narH) nitrate reductase subunit beta [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
IgA1 protease
|
iga
|
0.0008203 |
3 |
VF0147
|
Immune modulation |
(zmpC) immunoglobulin A1 protease [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
Capsule
|
FTT_RS04145
|
0.0076565 |
27 |
VF0543
|
Immune modulation |
(FTT_RS04145) glycosyltransferase family 2 protein [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
AdsA
|
adsA
|
0.0002734 |
1 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Pneumolysin
|
ply
|
0.0016407 |
6 |
VF0149
|
Exotoxin |
(ply) pneumolysin [Pneumolysin (VF0149) - Exotoxin (VFC0235)] [Streptococcus pneumoniae TIGR4]
|
|
Enterobactin
|
fepE
|
0.0008203 |
1 |
VF0228
|
Nutritional/Metabolic factor |
(fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
SodCI
|
sodCI
|
0.0002734 |
1 |
VF0109
|
Stress survival |
(sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
TTSS secreted effectors
|
espR1
|
0.002461 |
2 |
VF1110
|
Effector delivery system |
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
T7SS
|
essC
|
0.0005469 |
1 |
VF0581
|
Effector delivery system |
(essC) type VII secretion system protein EssC [T7SS (VF0581) - Effector delivery system (VFC0086)] [Bacillus anthracis str. Sterne]
|
|
EF-Tu
|
tufA
|
1.0199617 |
3,656 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
LPS
|
kdtB
|
0.0010938 |
4 |
VF0056
|
Immune modulation |
(kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
Colibactin
|
clbG
|
0.0008203 |
3 |
VF0573
|
Exotoxin |
(clbG) colibactin biosynthesis acyltransferase ClbG [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
VAS T6SS
|
clpB/vasG
|
0.0002734 |
1 |
VF0335
|
Effector delivery system |
(clpB/vasG) type VI secretion system AAA+ family ATPase [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MsrAB
|
msrA/B(pilB
|
0.0038283 |
14 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
SigA
|
sigA/rpoV
|
0.0016407 |
6 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
T6SS
|
rhs/PAAR
|
0.0002734 |
1 |
VF0579
|
Effector delivery system |
(rhs/PAAR) Type VI secretion system protein, PAAR family [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
EcbA
|
ecbA/fss3
|
0.002461 |
3 |
VF0539
|
Adherence |
(ecbA/fss3) Collagen binding MSCRAMM, EcbA/Fss3 [EcbA (VF0539) - Adherence (VFC0001)] [Enterococcus faecium DO]
|
|
Ebp pili
|
srtC
|
0.0008203 |
3 |
VF0538
|
Adherence |
(srtC) sortase [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Acm
|
acm
|
0.0005469 |
1 |
VF0419
|
Adherence |
(acm) collagen adhesin precursor Acm [Acm (VF0419) - Adherence (VFC0001)] [Enterococcus faecium str. TX2555]
|
|
LPS
|
rfbC
|
0.0010938 |
4 |
VF0171
|
Immune modulation |
(rfbC) dTDP-4-dehydrorhamnose 3,5-epimerase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
fabZ
|
0.0002734 |
1 |
VF0370
|
Immune modulation |
(fabZ) 3-hydroxyacyl-ACP dehydratase FabZ [LPS (VF0370) - Immune modulation (VFC0258)] [Bartonella henselae str. Houston-1]
|
|
Mitogenic factor
|
mf3
|
0.0831282 |
209 |
VF0252
|
Exoenzyme |
(mf3) deoxyribonuclease [Mitogenic factor (VF0252) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|