Research Article Details

Article ID: A17142
PMID: 27960079
Source: Cancer Cell
Title: Liver Cancer Checks in When Bile Acid Clocks Out.
Abstract: In this issue of Cancer Cell, Kettner et al. identify the disruption of normal circadian rhythmicity as an independent risk factor for hepatocellular carcinoma (HCC) in experimental animals and reveal opposing roles for the nuclear receptors FXR and CAR in disease progression from non-alcoholic fatty liver disease (NAFLD) to HCC.
DOI: 10.1016/j.ccell.2016.11.012