Research Article Details
| Article ID: | A21190 |
| PMID: | 25492154 |
| Source: | Zhonghua Liu Xing Bing Xue Za Zhi |
| Title: | [Relations between nonalcoholic fatty liver disease and metabolic syndrome]. |
| Abstract: | OBJECTIVE: To analyze the relation between nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) among adults from the Functional University Society (FUS). METHODS: This survey was conducted among the staff of Wuhan University who underwent physical check-ups from 2010 to 2011 at the Affiliated Hospital of Wuhan University. The participants had records related to medical history, clinical examination, anthropometry, laboratory tests and routine liver ultrasonography. According to the diagnostic criteria of NAFLD, the cases were divided into two groups-with NAFLD or without. MS and its relevant risk factors of the two groups were compared. RESULTS: 1) The prevalence rates of nonalcoholic fatty liver disease and MS were 20.7%, and 13.3%, respectively. People with nonalcoholic fatty liver disease had higher levels of BMI, SBP, DBP, TG, FPG and lower level of HDL-C than those who did not have the problem. 2) The risks of NAFLD group in developing MS, obesity, hypertension and dyslipidemia were higher than the non-group (P < 0.001). 3) The NAFLD group had 1.66, 4.22, 8.72 and 25.62 times chances of having 1 to 4 risk factors on MS than those without NAFLD. CONCLUSION: NAFLD was closely associated with MS and its relevant risk factors. |
| DOI: |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I12 | 10763 | Hypertension | An artery disease characterized by chronic elevated blood pressure in the arteries. https://en.wikipedia.org/wiki/Hypertension, https://www.ncbi.nlm.nih.gov/pubmed/24352797 | disease of anatomical entity/ cardiovascular system disease/vascular disease/ artery disease | Details |
| I13 | 3146 | Lipid metabolism disorder | An inherited metabolic disorder that involves the creation and degradation of lipids. http://en.wikipedia.org/wiki/Lipid_metabolism | disease of metabolism/ inherited metabolic disorder | Details |
| I14 | 9970 | Obesity | An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. https://en.wikipedia.org/wiki/Obesity | disease of metabolism/acquired metabolic disease/ nutrition disease/overnutrition | Details |