Research Article Details
| Article ID: | A22304 |
| PMID: | 26425524 |
| Source: | Endosc Ultrasound |
| Title: | Epicardial fat as the predictor for essential hypertension and early vascular damage in patients with metabolic syndrome and non-alcoholic fatty liver disease. |
| Abstract: | Increased visceral adiposity is a new marker of metabolic syndrome, early vascular damage, non-alcoholic fatty liver disease and also is associated with essential hypertension. Epicardial adipose tissue is a very important factor in the pathogenesis of coronary atherosclerosis. Hypertension is one of the most important risk factor for the development of coronary heart disease, stroke, congestive heart failure, and end-stage renal disease. Epicardial fat is an active endocrine organ producing a wide range of active molecules, which can affect vessels dramatically. |
| DOI: |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I16 | 6713 | Cerebrovascular disease | An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain. http://en.wikipedia.org/wiki/Cerebrovascular_disease, http://www.ncbi.nlm.nih.gov/books/NBK378/ | disease of anatomical entity/ cardiovascular system disease/ vascular disease/cerebrovascular disease | Details |
| I12 | 10763 | Hypertension | An artery disease characterized by chronic elevated blood pressure in the arteries. https://en.wikipedia.org/wiki/Hypertension, https://www.ncbi.nlm.nih.gov/pubmed/24352797 | disease of anatomical entity/ cardiovascular system disease/vascular disease/ artery disease | Details |
| I07 | 1936 | Arteriosclerosis | Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C35768 | disease of anatomical entity/cardiovascular system disease/ vascular disease/ artery disease | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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