Research Article Details
| Article ID: | A35166 |
| PMID: | 21558530 |
| Source: | J Med Biogr |
| Title: | George Cheyne (1671 or 73-1743): 18th-century physician. |
| Abstract: | George Cheyne was a well-known physician with a practice in Bath and London. He was a fat, jovial Scotsman weighing 32 stone at one time and with a great sense of humour who could be classed as one of the characters of the period. His health suffered seriously from eating and drinking too much in taverns with his 'bottle companions' when young, and he spent the rest of his life writing books for the public to help them avoid the problems he had experienced, with a particular emphasis on diet and nervous disorders. His book entitled An Essay on Health and Long Life had particular success. Although often lampooned, he had many famous patients including Beau Nash, Samuel Richardson, The Countess of Huntingdon and Catherine Walpole, the eldest daughter of the Prime Minister Robert Walpole. He was a skilled and caring doctor and health educator, and has been said to have established the agenda for psychiatric epidemiology. |
| DOI: | 10.1258/jmb.2010.010028 |
| Strategy ID | Therapy Strategy | Synonyms | Therapy Targets | Therapy Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I14 | 9970 | Obesity | An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. https://en.wikipedia.org/wiki/Obesity | disease of metabolism/acquired metabolic disease/ nutrition disease/overnutrition | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D328 | Serine | Chemical drug | DB00133 | SRR | Improve insulin resistance | Under clinical trials | Details |
| D579 | Emfilermin | Miscellany | -- | adipocytes | Enhance lipid metabolism | Under investigation | Details |
| D083 | CLA | Chemical drug | DB01211 | KCNH2; SLCO1B1; SLCO1B3 | -- | Under clinical trials | Details |
| D316 | S-adenosyl-L-methionine | Chemical drug | DB00118 | GNMT cofactor | Antiviral | Under clinical trials | Details |