Research Article Details

Article ID: A44982
PMID: 26530157
Source: Am J Physiol Endocrinol Metab
Title: Advances in high-density lipoprotein physiology: surprises, overturns, and promises.
Abstract: Emerging evidence strongly supports that changes in the HDL metabolic pathway, which result in changes in HDL proteome and function, appear to have a causative impact on a number of metabolic disorders. Here, we provide a critical review of the most recent and novel findings correlating HDL properties and functionality with various pathophysiological processes and disease states, such as obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, inflammation and sepsis, bone and obstructive pulmonary diseases, and brain disorders.
DOI: 10.1152/ajpendo.00429.2015