Research Article Details

Article ID: A45758
PMID: 22917635
Source: Dig Liver Dis
Title: Comment on "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property".
Abstract:
DOI: 10.1016/j.dld.2012.07.009

Strategy ID Therapy Strategy Synonyms Therapy Targets Therapy Drugs

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T08 Tumor necrosis factor TNF inhibitor Cytokine P01375 TNFA_HUMAN Details

Diseases ID DO ID Disease Name Definition Class
I13 3146 Lipid metabolism disorder An inherited metabolic disorder that involves the creation and degradation of lipids. http://en.wikipedia.org/wiki/Lipid_metabolism disease of metabolism/ inherited metabolic disorder Details

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D020 Atorvastatin Chemical drug DB01076 DPP4 inhibitor; AHR agonist; HDAC2 inhibitor; NR1I3 ligand Enhance lipid metabolism Under clinical trials Details