Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Caffeic acid28 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00834 | 34954022 | Free Radic Biol Med | Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage. | 2021 | Details |
| A03137 | 34117215 | Cell Death Dis | Liver fat storage is controlled by HNF4α through induction of lipophagy and is reversed by a potent HNF4α agonist. | 2021 | Details |
| A03463 | 33992352 | Food Res Int | Caffeic acid prevents non-alcoholic fatty liver disease induced by a high-fat diet through gut microbiota modulation in mice. | 2021 | Details |
| A05568 | 33204402 | Oxid Med Cell Longev | Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice. | 2020 | Details |
| A05908 | 33079307 | Arch Pharm Res | Emerging roles of ferroptosis in liver pathophysiology. | 2020 | Details |
| A09290 | 31804025 | Environ Toxicol | Burdock (Arctium lappa L.) root attenuates preneoplastic lesion development in a diet and thioacetamide-induced model of steatohepatitis-associated hepatocarcinogenesis. | 2019 | Details |
| A10338 | 31384531 | Acta Pharm Sin B | Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters. | 2019 | Details |
| A12649 | 30347674 | Nutrients | Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model. | 2018 | Details |
| A13316 | 30036051 | J Agric Food Chem | Cichoric Acid Prevents Free-Fatty-Acid-Induced Lipid Metabolism Disorders via Regulating Bmal1 in HepG2 Cells. | 2018 | Details |
| A13462 | 29960159 | Nutrition | Caffeic acid ameliorates hepatic steatosis and reduces ER stress in high fat diet-induced obese mice by regulating autophagy. | 2018 | Details |
| A13692 | 29803928 | Biomed Pharmacother | Protective effects of cichoric acid on H2O2-induced oxidative injury in hepatocytes and larval zebrafish models. | 2018 | Details |
| A14242 | 29508519 | Mol Nutr Food Res | Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR-γ and Inducing Adipose Tissue Remodeling in Diet-Induced Obese Mice. | 2018 | Details |
| A14721 | 29271886 | Nutrients | A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome. | 2017 | Details |
| A16002 | 28618991 | Curr Med Chem | Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions. | 2018 | Details |
| A16019 | 28608557 | J Food Sci | Salicornia Extract Ameliorates Salt-Induced Aggravation of Nonalcoholic Fatty Liver Disease in Obese Mice Fed a High-Fat Diet. | 2017 | Details |
| A16169 | 28526925 | Eur J Nutr | Polyphenolic extract attenuates fatty acid-induced steatosis and oxidative stress in hepatic and endothelial cells. | 2017 | Details |
| A16432 | 28393690 | Curr Med Chem | Hepatic AMP Kinase as a Potential Target for Treating Nonalcoholic Fatty Liver Disease: Evidence from Studies of Natural Products. | 2018 | Details |
| A16560 | 28317281 | Mol Nutr Food Res | Comparison of dietary polyphenols for protection against molecular mechanisms underlying nonalcoholic fatty liver disease in a cell model of steatosis. | 2017 | Details |
| A17120 | 27981809 | Mol Nutr Food Res | Chicoric acid attenuate a nonalcoholic steatohepatitis by inhibiting key regulators of lipid metabolism, fibrosis, oxidation, and inflammation in mice with methionine and choline deficiency. | 2017 | Details |
| A23119 | 24027117 | J Sci Food Agric | The inhibition of oleic acid induced hepatic lipogenesis and the promotion of lipolysis by caffeic acid via up-regulation of AMP-activated kinase. | 2013 | Details |
| A23641 | 23603006 | Food Chem Toxicol | Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARα and SREBP-1. | 2013 | Details |
| A44785 | 29546172 | AIMS Public Health | Beneficial Role of Coffee and Caffeine in Neurodegenerative Diseases: A Minireview. | 2016 | Details |
| A47830 | 31213776 | Drug Des Devel Ther | Salvianolic acid A attenuates CCl4-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways. | 2019 | Details |
| A49430 | 35751193 | Comput Biol Med | Exploring the possible molecular targeting mechanism of Saussurea involucrata in the treatment of COVID-19 based on bioinformatics and network pharmacology. | 2022 | Details |
| A49732 | 35655096 | Acta Pharmacol Sin | Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity. | 2022 | Details |
| A50264 | 35449947 | ACS Omega | Polyphenol-Rich Extracts of Xylopia and Aframomum Species Show Metabolic Benefits by Lowering Hepatic Lipid Accumulation in Diet-Induced Obese Mice. | 2022 | Details |
| A50300 | 35438556 | J Med Food | Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α. | 2022 | Details |
| A50776 | 35269912 | Int J Mol Sci | Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates. | 2022 | Details |