Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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DHA183 records.
Article ID | PMID | Source | Title | Publish Year | |
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A00141 | 35212227 | J Agric Food Chem | Targeted Lipidomics Reveal the Effects of Different Phospholipids on the Phospholipid Profiles of Hepatic Mitochondria and Endoplasmic Reticulum in High-Fat/High-Fructose-Diet-Induced Nonalcoholic Fatty Liver Disease Mice. | 2022 | Details |
A00187 | 35193889 | BMJ Open Gastroenterol | Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages-prospective study in Rajarata Pregnancy Cohort (RaPCo). | 2022 | Details |
A00478 | 35067753 | Eur J Nutr | The effects of fish oil plus vitamin D3 intervention on non-alcoholic fatty liver disease: a randomized controlled trial. | 2022 | Details |
A00524 | 35053404 | Cells | Role of Mitochondrial Cytochrome P450 2E1 in Healthy and Diseased Liver. | 2022 | Details |
A00604 | 35033554 | Eur J Pharmacol | Ursodesoxycholic acid is an FFA4 agonist and reduces hepatic steatosis via FFA4 signaling. | 2022 | Details |
A00760 | 34977519 | JHEP Rep | Pegbelfermin selectively reduces secondary bile acid concentrations in patients with non-alcoholic steatohepatitis. | 2021 | Details |
A00946 | 34922604 | Trials | Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the "Brazilian Omega Study" (BROS)-a randomized controlled trial. | 2021 | Details |
A01257 | 34813379 | Metab Syndr Relat Disord | The Myristic Acid:Docosahexaenoic Acid Ratio Versus the n-6 Polyunsaturated Fatty Acid:n-3 Polyunsaturated Fatty Acid Ratio as Nonalcoholic Fatty Liver Disease Biomarkers. | 2021 | Details |
A01687 | 34653759 | Biomed Pharmacother | Effects of DHA dietary intervention on hepatic lipid metabolism in apolipoprotein E-deficient and C57BL/6J wild-type mice. | 2021 | Details |
A01785 | 34618982 | FASEB J | Omega-3 carboxylic acids and fenofibrate differentially alter plasma lipid mediators in patients with non-alcoholic fatty liver disease. | 2021 | Details |
A02106 | 34505434 | Se Pu | [Identification of LAMTOR1-regulated metabolites using ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry in malignant transformation of liver inflammation]. | 2021 | Details |
A02296 | 34433051 | Cell Rep | Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria. | 2021 | Details |
A02899 | 34202667 | Biomolecules | The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
A02927 | 34195217 | Front Nutr | Grape Polyphenols Attenuate Diet-Induced Obesity and Hepatic Steatosis in Mice in Association With Reduced Butyrate and Increased Markers of Intestinal Carbohydrate Oxidation. | 2021 | Details |
A03148 | 34113260 | Front Physiol | Effect of ω-3 Polyunsaturated Fatty Acids-Derived Bioactive Lipids on Metabolic Disorders. | 2021 | Details |
A03508 | 33977946 | Food Funct | DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet. | 2021 | Details |
A04306 | 33671567 | Cells | Identification of Accessible Hepatic Gene Signatures for Interindividual Variations in Nutrigenomic Response to Dietary Supplementation of Omega-3 Fatty Acids. | 2021 | Details |
A04314 | 33668222 | Int J Environ Res Public Health | Tobacco Smoke and CYP1A2 Activity in a US Population with Normal Liver Enzyme Levels. | 2021 | Details |
A04548 | 33582286 | Biochim Biophys Acta Mol Cell Biol Lipids | Chronic systemic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver. | 2021 | Details |
A04584 | 33572810 | Nutrients | Krill Oil Supplementation Reduces Exacerbated Hepatic Steatosis Induced by Thermoneutral Housing in Mice with Diet-Induced Obesity. | 2021 | Details |
A04590 | 33571553 | J Hepatol | Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH. | 2021 | Details |
A04619 | 33560577 | Mol Nutr Food Res | Three Novel Dietary Phenolic Compounds from Pickled Raphanus Sativus L. Inhibit Lipid Accumulation in Obese Mice by Modulating the Gut Microbiota Composition. | 2021 | Details |
A04667 | 33546405 | Nutrients | Effects of Long-Term DHA Supplementation and Physical Exercise on Non-Alcoholic Fatty Liver Development in Obese Aged Female Mice. | 2021 | Details |
A04835 | 33490615 | JGH Open | Seroprevalence of Helicobacter pylori and its association with metabolic syndrome in a rural community of Bangladesh. | 2020 | Details |
A04840 | 33488295 | Mediators Inflamm | Associations among Dietary Omega-3 Polyunsaturated Fatty Acids, the Gut Microbiota, and Intestinal Immunity. | 2021 | Details |
A04988 | 33424294 | Saudi J Biol Sci | The protective effect of shrimp cooked in different methods on high-cholesterol- induced fatty liver in rats. | 2020 | Details |
A05590 | 33197790 | Environ Int | Unravelling the metabolic alterations of liver damage induced by thirdhand smoke. | 2020 | Details |
A05632 | 33182038 | Int Immunopharmacol | Resolvin D1 mitigates non-alcoholic steatohepatitis by suppressing the TLR4-MyD88-mediated NF-κB and MAPK pathways and activating the Nrf2 pathway in mice. | 2020 | Details |
A05707 | 33147705 | Nutrients | Impact of Long-Term Supplementation with Fish Oil in Individuals with Non-Alcoholic Fatty Liver Disease: A Double Blind Randomized Placebo Controlled Clinical Trial. | 2020 | Details |
A06162 | 32982112 | World J Gastroenterol | Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation. | 2020 | Details |
A06496 | 32853678 | J Nutr Biochem | N-3 PUFAs inhibited hepatic ER stress induced by feeding of a high-saturated fat diet accompanied by the expression LOX-1. | 2020 | Details |
A06668 | 32786869 | J Agric Food Chem | Combined Effect of Quercetin and Fish Oil on Oxidative Stress in the Liver of Mice Fed a Western-Style Diet. | 2020 | Details |
A07109 | 32620521 | Dig Liver Dis | Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration. | 2020 | Details |
A07197 | 32586350 | BMC Genomics | Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease. | 2020 | Details |
A07879 | 32325349 | Biomed Pharmacother | Gan-Jiang-Ling-Zhu decoction alleviates hepatic steatosis in rats by the miR-138-5p/CPT1B axis. | 2020 | Details |
A07961 | 32298755 | Mol Cell Endocrinol | The offspring from rats fed a fatty diet display impairments in the activation of liver peroxisome proliferator activated receptor alpha and features of fatty liver disease. | 2020 | Details |
A07974 | 32292967 | Food Funct | DHA substitution overcomes high-fat diet-induced disturbance in the circadian rhythm of lipid metabolism. | 2020 | Details |
A08138 | 32231762 | World J Hepatol | High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells. | 2020 | Details |
A08249 | 32188593 | BMJ Open Diabetes Res Care | Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism. | 2020 | Details |
A08309 | 32158242 | Diabetes Metab Syndr Obes | DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model. | 2020 | Details |
A08428 | 32115688 | Int J Cancer | Defects in long-chain 3-hydroxy acyl-CoA dehydrogenase lead to hepatocellular carcinoma: A novel etiology of hepatocellular carcinoma. | 2020 | Details |
A08523 | 32075238 | Nutrients | Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View. | 2020 | Details |
A08524 | 32075112 | Int J Mol Sci | Secondhand Smoke Induces Liver Steatosis through Deregulation of Genes Involved in Hepatic Lipid Metabolism. | 2020 | Details |
A08576 | 32054543 | Br J Nutr | Combined effect of n-3 fatty acids and phytosterol esters on alleviating hepatic steatosis in non-alcoholic fatty liver disease subjects: a double-blind placebo-controlled clinical trial. | 2020 | Details |
A08734 | 32007335 | Nutr Metab Cardiovasc Dis | Addition of fish oil to atherogenic high fat diet inhibited atherogenesis while olive oil did not, in LDL receptor KO mice. | 2019 | Details |
A09015 | 31903720 | Liver Int | Succinate-GPR-91 receptor signalling is responsible for nonalcoholic steatohepatitis-associated fibrosis: Effects of DHA supplementation. | 2020 | Details |
A09392 | 31762620 | Saudi J Biol Sci | Lifestyle interventions for non-alcoholic fatty liver disease. | 2019 | Details |
A09431 | 31752380 | Diagnostics (Basel) | Is the Fatty Acids Profile in Blood a Good Predictor of Liver Changes? Correlation of Fatty Acids Profile with Fatty Acids Content in the Liver. | 2019 | Details |
A09642 | 31661783 | Metabolites | A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice. | 2019 | Details |
A09934 | 31554528 | Br J Nutr | Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease. | 2020 | Details |
A10124 | 31474633 | Yakugaku Zasshi | [Involvement of the Free Fatty Acid Receptor GPR120/FFAR4 in the Development of Nonalcoholic Steatohepatitis]. | 2019 | Details |
A10860 | 31152791 | Free Radic Biol Med | Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease. | 2019 | Details |
A11149 | 31022865 | Nutrients | Dietary Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) Operate by Different Mechanisms to Modulate Hepatic Steatosis and Hyperinsulemia in fa/fa Zucker Rats. | 2019 | Details |
A11198 | 31003450 | Nutrients | Oxidative Stress and Non-Alcoholic Fatty Liver Disease: Effects of Omega-3 Fatty Acid Supplementation. | 2019 | Details |
A11265 | 30968772 | Curr Med Chem | Targeting n-3 Polyunsaturated Fatty Acids in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
A11325 | 30937580 | Eur J Nutr | Erythrocyte membrane n-3 polyunsaturated fatty acids are inversely associated with the presence and progression of nonalcoholic fatty liver disease in Chinese adults: a prospective study. | 2019 | Details |
A11530 | 30855276 | J Clin Invest | A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis. | 2019 | Details |
A11626 | 30813440 | Nutrients | Effect of Fish Oil Supplementation on Hepatic and Visceral Fat in Overweight Men: A Randomized Controlled Trial. | 2019 | Details |
A11756 | 30765737 | Sci Rep | Nutritional and lipidomics biomarkers of docosahexaenoic acid-based multivitamin therapy in pediatric NASH. | 2019 | Details |
A12103 | 30601174 | Curr Opin Clin Nutr Metab Care | Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children: where do we stand? | 2019 | Details |
A12152 | 30580553 | Crit Rev Food Sci Nutr | n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. | 2018 | Details |
A12274 | 30538803 | Oxid Med Cell Longev | Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet-Induced Accumulation of Lipid in the Liver of ApoE-/- Mice. | 2018 | Details |
A13031 | 30172659 | Clin Nutr | Marine omega-3 fatty acid supplementation in non-alcoholic fatty liver disease: Plasma proteomics in the randomized WELCOME* trial. | 2018 | Details |
A13128 | 30127297 | Nutrients | Evaluation of a High Concentrate Omega-3 for Correcting the Omega-3 Fatty Acid Nutritional Deficiency in Non-Alcoholic Fatty Liver Disease (CONDIN). | 2018 | Details |
A13141 | 30120404 | Pediatr Res | In a pilot study, reduced fatty acid desaturase 1 function was associated with nonalcoholic fatty liver disease and response to treatment in children. | 2018 | Details |
A13400 | 29996339 | Zhonghua Gan Zang Bing Za Zhi | [Effect of lipid-induced macrophage M1/M2 polarization on lipid metabolism in hepatocytes]. | 2018 | Details |
A13708 | 29798686 | Syst Biol Reprod Med | Effects of saturated palmitic acid and omega-3 polyunsaturated fatty acids on Sertoli cell apoptosis. | 2018 | Details |
A14128 | 29572342 | J Pharmacol Exp Ther | Protectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 Expression. | 2018 | Details |
A14469 | 29398867 | World J Gastroenterol | Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. | 2018 | Details |
A14574 | 29345914 | J Agric Food Chem | Comparative Analysis of EPA/DHA-PL Forage and Liposomes in Orotic Acid-Induced Nonalcoholic Fatty Liver Rats and Their Related Mechanisms. | 2018 | Details |
A14756 | 29253525 | Pharmacol Res | Crosstalk mechanisms in hepatoprotection: Thyroid hormone-docosahexaenoic acid (DHA) and DHA-extra virgin olive oil combined protocols. | 2017 | Details |
A14762 | 29249532 | Clin Nutr | Omega-3 PUFA modulate lipogenesis, ER stress, and mitochondrial dysfunction markers in NASH - Proteomic and lipidomic insight. | 2017 | Details |
A14817 | 29221950 | Eur J Pharmacol | DHA supplementation prevent the progression of NASH via GPR120 signaling. | 2017 | Details |
A14912 | 29175671 | J Nutr Biochem | Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. | 2017 | Details |
A15022 | 29126901 | Biochim Biophys Acta Mol Cell Biol Lipids | Omega-3 polyunsaturated fatty acids protect human hepatoma cells from developing steatosis through FFA4 (GPR120). | 2017 | Details |
A15133 | 29081885 | Oxid Med Cell Longev | Dietary Flaxseed Oil Prevents Western-Type Diet-Induced Nonalcoholic Fatty Liver Disease in Apolipoprotein-E Knockout Mice. | 2017 | Details |
A15167 | 29065507 | Nutrients | Fatty Acids Consumption: The Role Metabolic Aspects Involved in Obesity and Its Associated Disorders. | 2017 | Details |
A15374 | 28940752 | Mol Nutr Food Res | Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation. | 2017 | Details |
A15592 | 28824323 | Int J Med Sci | Rhododendron oldhamii leaf extract improves fatty liver syndrome by increasing lipid oxidation and decreasing the lipogenesis pathway in mice. | 2017 | Details |
A15857 | 28678821 | PLoS One | A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice. | 2017 | Details |
A16193 | 28511023 | Appl Physiol Nutr Metab | Efficacy of docosahexaenoic acid-choline-vitamin E in paediatric NASH: a randomized controlled clinical trial. | 2017 | Details |
A16384 | 28425467 | Sci Rep | Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis. | 2017 | Details |
A16389 | 28422962 | PLoS One | Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice. | 2017 | Details |
A16429 | 28395666 | Lipids Health Dis | Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice. | 2017 | Details |
A16495 | 28356106 | Lipids Health Dis | Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice. | 2017 | Details |
A16520 | 28341541 | Mol Aspects Med | Pro-resolving actions of SPM in adipose tissue biology. | 2017 | Details |
A16593 | 28294174 | Eur J Clin Nutr | Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study. | 2017 | Details |
A16808 | 28161092 | Clin Nutr | Fatty acid and non-alcoholic fatty liver disease: Meta-analyses of case-control and randomized controlled trials. | 2017 | Details |
A16949 | 28077733 | J Nutr | Identification of Potential Plasma Biomarkers for Nonalcoholic Fatty Liver Disease by Integrating Transcriptomics and Proteomics in Laying Hens. | 2017 | Details |
A16964 | 28073164 | Hepatology | Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice. | 2017 | Details |
A17127 | 27977757 | PLoS One | Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial. | 2016 | Details |
A17432 | 27710160 | Metab Syndr Relat Disord | Treatment of Nonalcoholic Fatty Liver Disease with Long-Chain n-3 Polyunsaturated Fatty Acids in Humans. | 2016 | Details |
A17542 | 27752492 | Prev Nutr Food Sci | Carrot Juice Administration Decreases Liver Stearoyl-CoA Desaturase 1 and Improves Docosahexaenoic Acid Levels, but Not Steatosis in High Fructose Diet-Fed Weanling Wistar Rats. | 2016 | Details |
A17964 | 27446914 | Front Cell Dev Biol | In vitro Modulation of the LPS-Induced Proinflammatory Profile of Hepatocytes and Macrophages- Approaches for Intervention in Obesity? | 2016 | Details |
A18131 | 27333187 | PLoS One | Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. | 2016 | Details |
A18220 | 27277347 | Mymensingh Med J | Comparative Study between Pentoxifylline and Pioglitazone in the Treatment of Non-Alcoholic Fatty Liver Disease among Newly Detected Glucose Intolerant Patients. | 2016 | Details |
A18402 | 27155918 | J Nutr Biochem | Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice. | 2016 | Details |
A18472 | 27106721 | Diabetologia | Higher body fat percentage is associated with enhanced temperature perception in NAFLD: results from the randomised Wessex Evaluation of fatty Liver and Cardiovascular markers in NAFLD with OMacor thErapy trial (WELCOME) trial. | 2016 | Details |
A18791 | 26937141 | World J Gastroenterol | Dietary saturated fatty acid and polyunsaturated fatty acid oppositely affect hepatic NOD-like receptor protein 3 inflammasome through regulating nuclear factor-kappa B activation. | 2016 | Details |
A18910 | 26873633 | Biochim Biophys Acta | iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. | 2016 | Details |