Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00007 | 35256601 | Cell Death Discov | LncRNA MEG3 up-regulates SIRT6 by ubiquitinating EZH2 and alleviates nonalcoholic fatty liver disease. | 2022 | Details |
| A00022 | 35251469 | Oxid Med Cell Longev | Farnesoid X Receptor Deficiency Induces Hepatic Lipid and Glucose Metabolism Disorder via Regulation of Pyruvate Dehydrogenase Kinase 4. | 2022 | Details |
| A00030 | 35250593 | Front Pharmacol | Combined Use of Bicyclol and Berberine Alleviates Mouse Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A00044 | 35246007 | Bioengineered | Quantitative proteomics analysis based on tandem mass tag labeling coupled with labeling coupled with liquid chromatography-tandem mass spectrometry discovers the effect of silibinin on non-alcoholic fatty liver disease in mice. | 2022 | Details |
| A00055 | 35240510 | Biochem Biophys Res Commun | Inulin activates FXR-FGF15 signaling and further increases bile acids excretion in non-alcoholic fatty liver disease mice. | 2022 | Details |
| A00056 | 35240344 | Cell Mol Gastroenterol Hepatol | Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis. | 2022 | Details |
| A00092 | 35222799 | Oxid Med Cell Longev | 4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes. | 2022 | Details |
| A00094 | 35222044 | Front Pharmacol | Antibiotic Disruption of the Gut Microbiota Enhances the Murine Hepatic Dysfunction Associated With a High-Salt Diet. | 2022 | Details |
| A00096 | 35220997 | Discov Med | Farnesoid X Receptor as a Promising Therapeutic Target for Nonalcoholic Fatty Liver Disease (NAFLD) and the Current Development of Its Agonists. | 2022 | Details |
| A00106 | 35217953 | Environ Sci Pollut Res Int | Environmental exposure to low-dose perfluorohexanesulfonate promotes obesity and non-alcoholic fatty liver disease in mice fed a high-fat diet. | 2022 | Details |
| A00121 | 35213002 | Methods Mol Biol | Analysis of the Sphingolipidome in NAFLD. | 2022 | Details |
| A00135 | 35212985 | Methods Mol Biol | Histopathological Diagnosis of Nonalcoholic Steatohepatitis (NASH). | 2022 | Details |
| A00136 | 35212984 | Methods Mol Biol | Measurement of Hepatic Lipids. | 2022 | Details |
| A00174 | 35198905 | iScience | Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity. | 2022 | Details |
| A00177 | 35197460 | Nat Commun | Kindlin-2 haploinsufficiency protects against fatty liver by targeting Foxo1 in mice. | 2022 | Details |
| A00183 | 35195377 | Minerva Endocrinol (Torino) | Inflammation is associated with impairment of oxidative status, carbohydrate and lipid metabolism in type 2 diabetes complicated by non-alcoholic fatty liver disease. | 2022 | Details |
| A00188 | 35192934 | Mol Ther | Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma. | 2022 | Details |
| A00205 | 35187676 | J Food Biochem | Chitosan oligosaccharide attenuates hepatic steatosis in HepG2 cells via the activation of AMP-activated protein kinase. | 2022 | Details |
| A00209 | 35185113 | J Pediatr Gastroenterol Nutr | Comparison of the Lipidomic Signature of Fatty Liver in Children and Adults: A Cross-Sectional Study. | 2022 | Details |
| A00214 | 35182330 | Mol Cell Biochem | Menin regulates lipid deposition in mouse hepatocytes via interacting with transcription factor FoxO1. | 2022 | Details |
| A00223 | 35178098 | Evid Based Complement Alternat Med | A Network Pharmacology Study on the Active Components and Targets of the Radix Ginseng and Radix Bupleuri Herb Pair for Treating Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A00225 | 35176709 | Biomed Pharmacother | Purendan alleviates non-alcoholic fatty liver disease in aged type 2 diabetic rats via regulating mTOR/S6K1/SREBP-1c signaling pathway. | 2022 | Details |
| A00229 | 35174500 | J Sci Food Agric | Identification of a novel probiotic and its protective effects on NAFLD via modulating gut microbial community. | 2022 | Details |
| A00231 | 35174195 | Front Nutr | Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults. | 2022 | Details |
| A00235 | 35172845 | Nutr Metab (Lond) | Effects of exercise on high-fat diet-induced non-alcoholic fatty liver disease and lipid metabolism in ApoE knockout mice. | 2022 | Details |
| A00248 | 35166723 | Clin Transl Gastroenterol | Relationship between hepatic gene expression, intestinal microbiota and inferred functional metagenomic analysis in NAFLD. | 2022 | Details |
| A00253 | 35164140 | Molecules | A Comparison of the Gene Expression Profiles of Non-Alcoholic Fatty Liver Disease between Animal Models of a High-Fat Diet and Methionine-Choline-Deficient Diet. | 2022 | Details |
| A00256 | 35163881 | Molecules | The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models. | 2022 | Details |
| A00265 | 35160340 | J Clin Med | Effects of Moderate Alcohol Consumption in Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00288 | 35152443 | J Food Sci | Bentong ginger oleoresin mitigates liver injury and modulates gut microbiota in mouse with nonalcoholic fatty liver disease induced by high-fat diet. | 2022 | Details |
| A00296 | 35147302 | Hepatol Commun | Effect of Omega-3 Polyunsaturated Fatty Acids on Lipid Metabolism in Patients With Metabolic Syndrome and NAFLD. | 2022 | Details |
| A00303 | 35144334 | Endocrinol Metab (Seoul) | Dulaglutide Ameliorates Palmitic Acid-Induced Hepatic Steatosis by Activating FAM3A Signaling Pathway. | 2022 | Details |
| A00318 | 35140289 | Sci Rep | Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway. | 2022 | Details |
| A00326 | 35134438 | Life Sci | Fluorene-9-bisphenol exposure decreases locomotor activity and induces lipid-metabolism disorders by impairing fatty acid oxidation in zebrafish. | 2022 | Details |
| A00331 | 35133139 | Environ Sci Technol | 3-tert-Butyl-4-hydroxyanisole Impairs Hepatic Lipid Metabolism in Male Mice Fed with a High-Fat Diet. | 2022 | Details |
| A00332 | 35133032 | FASEB J | TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. | 2022 | Details |
| A00333 | 35132345 | Oxid Med Cell Longev | Differentially Expressed Hepatic Genes Revealed by Transcriptomics in Pigs with Different Liver Lipid Contents. | 2022 | Details |
| A00348 | 35126113 | Front Pharmacol | Fenofibrate Improves Insulin Resistance and Hepatic Steatosis and Regulates the Let-7/SERCA2b Axis in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Mice. | 2022 | Details |
| A00352 | 35124446 | J Pharm Biomed Anal | Targeted metabolomics profiles serum fatty acids by HFD induced non-alcoholic fatty liver in mice based on GC-MS. | 2022 | Details |
| A00363 | 35119232 | J Basic Clin Physiol Pharmacol | Is it possible to treat nonalcoholic liver disease using a flavanol-based nutraceutical approach? Basic and clinical data. | 2022 | Details |
| A00383 | 35108454 | FEBS Open Bio | Carbonic anhydrase 3 increases during liver adipogenesis even in pre-obesity, and its inhibitors reduce liver adipose accumulation. | 2022 | Details |
| A00384 | 35108315 | PLoS One | Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency. | 2022 | Details |
| A00389 | 35104782 | Ecotoxicol Environ Saf | Chronic lead exposure induces fatty liver disease associated with the variations of gut microbiota. | 2022 | Details |
| A00413 | 35093393 | Biochem Pharmacol | Targeting lipophagy as a potential therapeutic strategy for nonalcoholic fatty liver disease. | 2022 | Details |
| A00420 | 35091821 | Diabetologia | Adiponectin deficiency induces hepatic steatosis during pregnancy and gestational diabetes in mice. | 2022 | Details |
| A00432 | 35086000 | Food Chem | Amelioration action of gastrodigenin rhamno-pyranoside from Moringa seeds on non-alcoholic fatty liver disease. | 2022 | Details |
| A00449 | 35078487 | Chin Med | Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice. | 2022 | Details |
| A00450 | 35077907 | Environ Toxicol Pharmacol | Enterobacter cloacae aggravates metabolic disease by inducing inflammation and lipid accumulation. | 2022 | Details |
| A00477 | 35068225 | Exp Biol Med (Maywood) | Impact of spexin on metabolic diseases and inflammation: An updated minireview. | 2022 | Details |
| A00479 | 35067233 | Nutr Res Rev | MITOCHONDRIAL DYSFUNCTION AND EPIGENETICS UNDERLYING THE LINK BETWEEN EARLY-LIFE NUTRITION AND NON-ALCOHOLIC FATTY LIVER DISEASE. | 2022 | Details |
| A00496 | 35061665 | PLoS Biol | Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ. | 2022 | Details |
| A00504 | 35058782 | Front Pharmacol | TMEM88 Modulates Lipid Synthesis and Metabolism Cytokine by Regulating Wnt/β-Catenin Signaling Pathway in Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00509 | 35057689 | Expert Rev Gastroenterol Hepatol | Research progress on the relationship between TM6SF2 rs58542926 polymorphism and non-alcoholic fatty liver disease. | 2022 | Details |
| A00515 | 35055177 | Int J Mol Sci | Inulin Improves Diet-Induced Hepatic Steatosis and Increases Intestinal Akkermansia Genus Level. | 2022 | Details |
| A00533 | 35052765 | Biomedicines | Bifidobacterium bifidum Shows More Diversified Ways of Relieving Non-Alcoholic Fatty Liver Compared with Bifidobacterium adolescentis. | 2021 | Details |
| A00540 | 35052597 | Antioxidants (Basel) | Gallic Acid Improves Diabetic Steatosis by Downregulating MicroRNA-34a-5p through Targeting NFE2L2 Expression in High-Fat Diet-Fed db/db Mice. | 2021 | Details |
| A00541 | 35052595 | Antioxidants (Basel) | Oxidative Stress Is a Key Modulator in the Development of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00544 | 35052547 | Antioxidants (Basel) | Preventive Effects of β-Cryptoxanthin, a Potent Antioxidant and Provitamin A Carotenoid, on Lifestyle-Related Diseases-A Central Focus on Its Effects on Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A00547 | 35051553 | Mol Cell Endocrinol | Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes. | 2022 | Details |
| A00551 | 35048923 | Food Funct | Feeding of cuticles from Tenebrio molitor larvae modulates the gut microbiota and attenuates hepatic steatosis in obese Zucker rats. | 2022 | Details |
| A00564 | 35045647 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of sodium butyrate in metabolic-associated fatty liver disease]. | 2021 | Details |
| A00567 | 35045632 | Zhonghua Gan Zang Bing Za Zhi | [Study on plasma Golgi protein 73 and related models in the diagnosis of nonalcoholic fatty liver disease]. | 2021 | Details |
| A00579 | 35041255 | Phytother Res | Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease. | 2022 | Details |
| A00583 | 35040254 | Chem Biol Drug Des | SU5, a new Auraptene analog with improved metabolic stability, ameliorates nonalcoholic fatty liver disease in methionine- and choline-deficient diet-fed db/db mice. | 2022 | Details |
| A00595 | 35035496 | Evid Based Complement Alternat Med | Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARα Signaling Pathway. | 2022 | Details |
| A00615 | 35028346 | Data Brief | Dataset for liver metabolomic profile of highland barley Monascus purpureus went extract-treated golden hamsters with nonalcoholic fatty liver disease. | 2021 | Details |
| A00624 | 35024184 | J Adv Res | Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism. | 2021 | Details |
| A00638 | 35018944 | Food Funct | Ginsenoside CK ameliorates hepatic lipid accumulation via activating the LKB1/AMPK pathway in vitro and in vivo. | 2022 | Details |
| A00640 | 35018684 | Phytother Res | Banana green peels extract protects against nonalcoholic fatty liver disease in high-fat-fed mice through modulation of lipid metabolism and inflammation. | 2022 | Details |
| A00642 | 35016999 | J Nutr Biochem | Gestational hypercholesterolemia programs hepatic steatosis in a sex-specific manner in ApoE-deficient mice. | 2022 | Details |
| A00647 | 35015019 | Food Funct | Preventive effects of black soybean polyphenols on non-alcoholic fatty liver disease in three different mouse models. | 2022 | Details |
| A00650 | 35014168 | Basic Clin Pharmacol Toxicol | Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs. | 2022 | Details |
| A00656 | 35013417 | Sci Rep | Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver. | 2022 | Details |
| A00658 | 35013040 | J Oleo Sci | Pink Lotus Essential Oil and Alleviates on Free Fatty Acid Induced Steatosis in HepG2 Cells via PI3K/Akt and NF-κB Pathways. | 2022 | Details |
| A00660 | 35011746 | J Clin Med | Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles. | 2021 | Details |
| A00665 | 35010950 | Nutrients | Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis. | 2021 | Details |
| A00668 | 35009003 | Int J Mol Sci | Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A00671 | 35008682 | Int J Mol Sci | Emerging Roles of Calcium Signaling in the Development of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00678 | 35005119 | Genes Dis | Comparison of hepatic gene expression profiles between three mouse models of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00679 | 35005107 | Genes Dis | Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders. | 2021 | Details |
| A00688 | 35003024 | Front Microbiol | Effect of Chinese Herbal Medicine Mixture 919 Syrup on Regulation of the Ghrelin Pathway and Intestinal Microbiota in Rats With Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A00693 | 35001345 | J Physiol Biochem | Vaspin attenuates steatosis-induced fibrosis via GRP78 receptor by targeting AMPK signaling pathway. | 2022 | Details |
| A00708 | 34993571 | Diabetologia | Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial. | 2022 | Details |
| A00710 | 34993216 | Front Med (Lausanne) | Alterations in the Gut Microbiota and Hepatitis-B-Virus Infection in Southern Chinese Patients With Coexisting Non-Alcoholic Fatty Liver Disease and Type-2 Diabetes Mellitus. | 2021 | Details |
| A00713 | 34992541 | Front Pharmacol | Diammonium Glycyrrhizinate Ameliorates Obesity Through Modulation of Gut Microbiota-Conjugated BAs-FXR Signaling. | 2021 | Details |
| A00714 | 34992540 | Front Pharmacol | Transcriptomic Analysis Reveals the Protective Effects of Empagliflozin on Lipid Metabolism in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00717 | 34990887 | Cell Mol Gastroenterol Hepatol | Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. | 2022 | Details |
| A00718 | 34990729 | Toxicol Appl Pharmacol | Whole life exposure to low dose cadmium alters diet-induced NAFLD. | 2022 | Details |
| A00719 | 34990473 | PLoS One | Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolism. | 2022 | Details |
| A00725 | 34988225 | Biomed Res Int | Target Deconvolution of Fenofibrate in Nonalcoholic Fatty Liver Disease Using Bioinformatics Analysis. | 2021 | Details |
| A00726 | 34988202 | Ann Transl Med | Y-box binding protein 1 regulates liver lipid metabolism by regulating the Wnt/β-catenin signaling pathway. | 2021 | Details |
| A00728 | 34986838 | Cancer Cell Int | STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway. | 2022 | Details |
| A00731 | 34986301 | Endocrinol Metab (Seoul) | The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE-/-FXR-/- Mice. | 2021 | Details |
| A00748 | 34981123 | Biosci Rep | Tandem mass tag-based proteomics analysis of type 2 diabetes mellitus with non-alcoholic fatty liver disease in mice treated with acupuncture. | 2022 | Details |
| A00753 | 34979169 | Toxicology | Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice. | 2022 | Details |
| A00780 | 34969770 | Anticancer Res | Development of Non-alcoholic Steatohepatitis and Nodular Regenerative Hyperplasia in C57BL/6J Mice Fed a Fructose-containing Western Diet. | 2022 | Details |
| A00781 | 34967286 | Mini Rev Med Chem | Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism. | 2021 | Details |
| A00787 | 34966475 | Oxid Med Cell Longev | Structural and Functional Modulation of Gut Microbiota by Jiangzhi Granules during the Amelioration of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00796 | 34964438 | Elife | Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA. | 2021 | Details |
| A00807 | 34959755 | Nutrients | The Effects of Butyrate on Induced Metabolic-Associated Fatty Liver Disease in Precision-Cut Liver Slices. | 2021 | Details |