Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipodystrophy156 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00029 | 35250856 | Front Endocrinol (Lausanne) | Not Enough Fat: Mouse Models of Inherited Lipodystrophy. | 2022 | Details |
| A00656 | 35013417 | Sci Rep | Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver. | 2022 | Details |
| A01485 | 34728268 | Presse Med | Complications of lipodystrophy syndromes. | 2021 | Details |
| A01881 | 34574647 | Int J Environ Res Public Health | Bone Mineral Density in Congenital Generalized Lipodystrophy: The Role of Bone Marrow Tissue, Adipokines, and Insulin Resistance. | 2021 | Details |
| A01986 | 34540943 | Visc Med | Excess Body Weight and Metabolic (Dysfunction)-Associated Fatty Liver Disease (MAFLD). | 2021 | Details |
| A02667 | 34292171 | Eur J Endocrinol | A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA founder variant highlights the multifaceted cardiac manifestations of metabolic laminopathies. | 2021 | Details |
| A03782 | 33865898 | Metabolism | Collagen β(1-O) galactosyltransferase 2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMW adiponectin in mice. | 2021 | Details |
| A03794 | 33862045 | Metabolism | Determinants of hepatic insulin clearance - Results from a Mendelian Randomization study. | 2021 | Details |
| A04067 | 33771728 | Mol Metab | Ube2i deletion in adipocytes causes lipoatrophy in mice. | 2021 | Details |
| A06058 | 33025629 | NMR Biomed | In vivo absolute quantification of hepatic γ-ATP concentration in mice using 31 P MRS at 11.7 T. | 2020 | Details |
| A07231 | 32573497 | JCI Insight | Leptin decreases de novo lipogenesis in patients with lipodystrophy. | 2020 | Details |
| A07236 | 32572196 | Nat Biomed Eng | Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin. | 2020 | Details |
| A07302 | 32548202 | ACG Case Rep J | Hepatic Steatosis Resulting From LMNA-Associated Familial Lipodystrophy. | 2020 | Details |
| A08822 | 31978277 | Mol Nutr Food Res | Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. | 2020 | Details |
| A10298 | 31393852 | JCI Insight | Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. | 2019 | Details |
| A10317 | 31388628 | Hepatol Commun | Body Composition and Genetic Lipodystrophy Risk Score Associate With Nonalcoholic Fatty Liver Disease and Liver Fibrosis. | 2019 | Details |
| A10722 | 31222048 | Nat Commun | Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis. | 2019 | Details |
| A10893 | 31136997 | Top Antivir Med | Fatty liver disease in persons with HIV infection. | 2019 | Details |
| A10905 | 31131845 | Clin Infect Dis | Natural Course of Nonalcoholic Fatty Liver Disease and Type 2 Diabetes in Patients With Human Immunodeficiency Virus With and Without Combination Antiretroviral Therapy-associated Lipodystrophy: A 16-Year Follow-up Study. | 2020 | Details |
| A11043 | 31071311 | Metabolism | Fatty liver in lipodystrophy: A review with a focus on therapeutic perspectives of adiponectin and/or leptin replacement. | 2019 | Details |
| A11166 | 31013363 | Hepatology | MRI Assessment of Treatment Response in HIV-associated NAFLD: A Randomized Trial of a Stearoyl-Coenzyme-A-Desaturase-1 Inhibitor (ARRIVE Trial). | 2019 | Details |
| A11528 | 30856468 | J Nutr Biochem | Tissue-dependent effects of cis-9,trans-11- and trans-10,cis-12-CLA isomers on glucose and lipid metabolism in adult male mice. | 2019 | Details |
| A12185 | 30570529 | J Acquir Immune Defic Syndr | Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study. | 2019 | Details |
| A12253 | 30545408 | J Med Case Rep | Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports. | 2018 | Details |
| A13010 | 30182761 | Endocr Res | A subset of patients with acquired partial lipodystrophy developing severe metabolic abnormalities. | 2018 | Details |
| A13501 | 29947044 | Clin Endocrinol (Oxf) | High Irisin levels in nondiabetic HIV-infected males are associated with insulin resistance, nonalcoholic fatty liver disease, and subclinical atherosclerosis. | 2018 | Details |
| A14564 | 29351486 | Am J Physiol Endocrinol Metab | Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. | 2017 | Details |
| A15436 | 28913408 | Cell Mol Gastroenterol Hepatol | Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis. | 2017 | Details |
| A15449 | 28902428 | Hepatology | Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease. | 2018 | Details |
| A16268 | 28476236 | Endocrinol Metab Clin North Am | Genetics of Lipodystrophy. | 2017 | Details |
| A16280 | 28471945 | AIDS | Metabolic concerns in aging HIV-infected persons: from serum lipid phenotype to fatty liver. | 2017 | Details |
| A16534 | 28330852 | FASEB J | A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice. | 2017 | Details |
| A16543 | 28324110 | J Clin Endocrinol Metab | Effects of Metreleptin in Pediatric Patients With Lipodystrophy. | 2017 | Details |
| A16760 | 28199729 | Clin Endocrinol (Oxf) | Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort. | 2017 | Details |
| A18328 | 27207510 | Diabetes | Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. | 2016 | Details |
| A18898 | 26880786 | J Lipid Res | Mogat1 deletion does not ameliorate hepatic steatosis in lipodystrophic (Agpat2-/-) or obese (ob/ob) mice. | 2016 | Details |
| A19112 | 26756202 | Diabet Med | Familial partial lipodystrophy linked to a novel peroxisome proliferator activator receptor -γ (PPARG) mutation, H449L: a comparison of people with this mutation and those with classic codon 482 Lamin A/C (LMNA) mutations. | 2016 | Details |
| A19473 | 26539645 | Oncotarget | Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. | 2015 | Details |
| A19549 | 26493063 | Curr Atheroscler Rep | Novel Approaches to Targeting Visceral and Hepatic Adiposities in HIV-Associated Lipodystrophy. | 2015 | Details |
| A20251 | 26063386 | Expert Opin Biol Ther | Metreleptin and generalized lipodystrophy and evolving therapeutic perspectives. | 2015 | Details |
| A21212 | 25477509 | J Biol Chem | Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice. | 2014 | Details |
| A21308 | 25415231 | Horm Metab Res | Leptin improves fatty liver independently of insulin sensitization and appetite suppression in hepatocyte-specific Pten-deficient mice with insulin hypersensitivity. | 2014 | Details |
| A21842 | 25008241 | Mol Cell Endocrinol | Role of aquaglyceroporins and caveolins in energy and metabolic homeostasis. | 2014 | Details |
| A21902 | 24973357 | J Endocrinol | 20 years of leptin: leptin in common obesity and associated disorders of metabolism. | 2014 | Details |
| A22003 | 24899308 | Nature | The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. | 2014 | Details |
| A22647 | 24384368 | Semin Cell Dev Biol | Nuclear envelope-related lipodystrophies. | 2013 | Details |
| A22832 | 24275555 | Biochim Biophys Acta | Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring. | 2013 | Details |
| A23143 | 24007548 | Am J Transplant | Post-liver transplant leptin results in resolution of severe recurrence of lipodystrophy-associated nonalcoholic steatohepatitis. | 2013 | Details |
| A23171 | 23985000 | Expert Rev Gastroenterol Hepatol | Leptin in the treatment of lipodystrophy-associated nonalcoholic fatty liver disease: are we there already? | 2013 | Details |
| A23196 | 23970949 | Oxid Med Cell Longev | Role of mitochondria in HIV infection and associated metabolic disorders: focus on nonalcoholic fatty liver disease and lipodystrophy syndrome. | 2013 | Details |
| A23244 | 23929732 | Hepatology | Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. | 2014 | Details |
| A23289 | 23896376 | Biochimie | Ectopic lipid accumulation: A potential cause for metabolic disturbances and a contributor to the alteration of kidney function. | 2013 | Details |
| A23650 | 23597924 | Med Mal Infect | Liver stiffness values in HIV-infected patients with isolated anti-hepatitis B core antibodies. | 2013 | Details |
| A23836 | 23439261 | J Hepatol | The liver diseases of lipodystrophy: the long-term effect of leptin treatment. | 2013 | Details |
| A23839 | 23433827 | Med Hypotheses | Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation? | 2013 | Details |
| A24364 | 22965160 | Horm Res Paediatr | Consequences of stopping and restarting leptin in an adolescent with lipodystrophy. | 2012 | Details |
| A24551 | 22760655 | Semin Liver Dis | Nonalcoholic fatty liver disease and HIV infection. | 2012 | Details |
| A24724 | 22560210 | Cell Metab | Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance. | 2012 | Details |
| A26876 | 19601771 | Curr HIV Res | The changing face of HIV/AIDS in treated patients. | 2009 | Details |
| A28096 | 16439872 | AIDS | Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients. | 2006 | Details |
| A28175 | 16225477 | Aliment Pharmacol Ther | Review article: hepatic steatosis and insulin resistance. | 2005 | Details |
| A28193 | 16198620 | Hepatol Res | Insulin resistance and clinical aspects of non-alcoholic steatohepatitis (NASH). | 2005 | Details |
| A28240 | 15989431 | AIDS Patient Care STDS | Hepatic steatosis and HIV infection. | 2005 | Details |
| A28246 | 15970496 | Front Biosci | Non-alcoholic fatty liver disease (NAFLD) in children. | 2005 | Details |
| A28371 | 15371930 | Eur J Gastroenterol Hepatol | The wide spectrum of steatohepatitis: a report of four cases and a review of the literature. | 2004 | Details |
| A35932 | 19390649 | PPAR Res | PPAR and liver injury in HIV-infected patients. | 2009 | Details |
| A37390 | 15791619 | Hepatology | Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy. | 2005 | Details |
| A42263 | 35046902 | Front Endocrinol (Lausanne) | Molecular and Cellular Bases of Lipodystrophy Syndromes. | 2022 | Details |
| A43265 | 32120400 | Ann Intern Med | Lipodystrophic Nonalcoholic Fatty Liver Disease Induced by Immune Checkpoint Blockade. | 2020 | Details |
| A43514 | 31538647 | Clin Infect Dis | Nonalcoholic Fatty Liver Disease in Human Immunodeficiency Virus: The (Not So) New Kid on the Block? | 2020 | Details |
| A43515 | 31538645 | Clin Infect Dis | Reply to Krahn and Sebastiani. | 2020 | Details |
| A43801 | 30844749 | Endocr Connect | Lipodystrophy-like features after total body irradiation among survivors of childhood acute leukemia. | 2019 | Details |
| A44024 | 30131393 | Diabetes | The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy. | 2018 | Details |
| A44159 | 29549040 | Gastroenterology | Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease. | 2018 | Details |
| A44240 | 29264552 | J Endocr Soc | Congenital Generalized Lipodystrophy Type 2 in a Patient From a High-Prevalence Area. | 2017 | Details |
| A44380 | 28768170 | Cell Metab | Causes, Characteristics, and Consequences of Metabolically Unhealthy Normal Weight in Humans. | 2017 | Details |
| A44925 | 26780008 | Curr Opin Lipidol | Gene-based therapies in lipidology: current status and future challenges. | 2015 | Details |
| A45328 | 25156686 | Metabolism | Leptin treatment: facts and expectations. | 2014 | Details |
| A45341 | 25114292 | Diabetes | Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy. | 2014 | Details |
| A45541 | 24026869 | Curr Diab Rep | What the genetics of lipodystrophy can teach us about insulin resistance and diabetes. | 2013 | Details |
| A45646 | 23475416 | Endocr Rev | Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. | 2013 | Details |
| A45962 | 21819679 | Comp Med | The effects of diet composition on body fat and hepatic steatosis in an animal (Peromyscus californicus) model of the metabolic syndrome. | 2011 | Details |
| A46017 | 21536711 | Endocr Rev | Genetic syndromes of severe insulin resistance. | 2011 | Details |
| A46334 | 19472314 | Hepatology | Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids. | 2009 | Details |
| A46398 | 19046821 | Med Hypotheses | Adipose tissue transplantation may be a potential treatment for diabetes, atherosclerosis and nonalcoholic steatohepatitis. | 2008 | Details |
| A46489 | 18344805 | Medicine (Baltimore) | Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. | 2008 | Details |
| A46734 | 16098839 | Am J Cardiol | Management of dyslipidemia in patients with complicated metabolic syndrome. | 2005 | Details |
| A46801 | 15331066 | Clin Liver Dis | Mitochondria in nonalcoholic fatty liver disease. | 2004 | Details |
| A46808 | 15151470 | Expert Rev Cardiovasc Ther | Treatment of metabolic syndrome. | 2004 | Details |
| A47483 | 2295475 | Hepatology | The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. | 1990 | Details |
| A47699 | 33491315 | Obesity (Silver Spring) | The Metabolic Equivalent BMI in Patients with Familial Partial Lipodystrophy (FPLD) Compared with Those with Severe Obesity. | 2021 | Details |
| A47770 | 32213649 | Endocrinol Diabetes Metab Case Rep | The complicated clinical course in a case of atypical lipodystrophy after development of neutralizing antibody to metreleptin: treatment with setmelanotide. | 2020 | Details |
| A47815 | 31434650 | Diabetes Care | Acquired Generalized Lipodystrophy: A New Cause of Anti-PD-1 Immune-Related Diabetes. | 2019 | Details |
| A47904 | 29607946 | Intern Med | Clinical Characteristics, Phenotype of Lipodystrophy and a Genetic Analysis of Six Diabetic Japanese Women with Familial Partial Lipodystrophy in a Diabetic Outpatient Clinic. | 2018 | Details |
| A48239 | 18989143 | Eur J Gastroenterol Hepatol | Hepatic histopathology and clinical characteristics associated with antiretroviral therapy in HIV patients without viral hepatitis. | 2008 | Details |
| A48270 | 17940115 | J Clin Endocrinol Metab | Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy. | 2007 | Details |
| A48319 | 16772767 | Am J Ther | Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk. | 2006 | Details |
| A48338 | 16181372 | Am J Gastroenterol | Hepatic steatosis in Dunnigan-type familial partial lipodystrophy. | 2005 | Details |
| A48361 | 15240593 | J Clin Endocrinol Metab | Proteinuric nephropathy in acquired and congenital generalized lipodystrophy: baseline characteristics and course during recombinant leptin therapy. | 2004 | Details |
| A48392 | 12663460 | Diabetes | Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. | 2003 | Details |