Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08791 | 31982488 | Pharmacol Res | Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo. | 2020 | Details |
| A08796 | 31981593 | Peptides | The new mechanism of Ghrelin/GHSR-1a on autophagy regulation. | 2020 | Details |
| A08830 | 31974458 | Sci Rep | Association between non-alcoholic fatty liver disease and coronary calcification depending on sex and obesity. | 2020 | Details |
| A08838 | 31969816 | Front Pharmacol | Genetics of Non-Alcoholic Fatty Liver and Cardiovascular Disease: Implications for Therapy? | 2020 | Details |
| A08844 | 31969087 | Curr Pharm Des | Genetics and Epigenetics in the Clinic: Precision Medicine in the Management of Fatty Liver Disease. | 2020 | Details |
| A08886 | 31952573 | Adv Clin Chem | Organokines in disease. | 2019 | Details |
| A08888 | 31952262 | Int J Mol Sci | Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia. | 2020 | Details |
| A08910 | 31941880 | Med Sci Monit | Electrocardiogram-Based R Wave Pulse Wave Index for Assessment of Carotid Atherosclerosis. | 2020 | Details |
| A08913 | 31941015 | Int J Mol Sci | Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences. | 2020 | Details |
| A08948 | 31928475 | Expert Opin Investig Drugs | NASH (nonalcoholic steatohepatitis), diabetes, and macrovascular disease: multiple chronic conditions and a potential treatment at the metabolic root. | 2020 | Details |
| A08964 | 31923423 | Clin Chim Acta | Triglyceride metabolism and angiopoietin-like proteins in lipoprotein lipase regulation. | 2020 | Details |
| A08971 | 31920962 | Front Endocrinol (Lausanne) | Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases. | 2019 | Details |
| A08973 | 31919793 | Pharmacoeconomics | Systematic Literature Review and Critical Appraisal of Health Economic Models Used in Cost-Effectiveness Analyses in Non-Alcoholic Steatohepatitis: Potential for Improvements. | 2020 | Details |
| A08984 | 31915606 | J Clin Transl Hepatol | Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09008 | 31906711 | Physiol Int | A brief review on the rising incidence of chronic kidney diseases and non-alcoholic fatty liver disease. | 2019 | Details |
| A09020 | 31902357 | Mini Rev Med Chem | Phytoestrogens and NAFLD: Possible Mechanisms of Action. | 2020 | Details |
| A09040 | 31893310 | Cell Mol Life Sci | Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism. | 2019 | Details |
| A09047 | 31889754 | J Clin Exp Hepatol | Antidiabetic Drugs and Statins in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09057 | 34350368 | Cardiol Plus | Bile Acid and Cholesterol Metabolism in Atherosclerotic Cardiovascular Disease and Therapy. | 2020 | Details |
| A09058 | 33837698 | Curr Top Membr | Membrane modulatory effects of omega-3 fatty acids: Analysis of molecular level interactions. | 2020 | Details |
| A09063 | 31887443 | Clin Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Fibrosis Associated With Increased Risk of Cardiovascular Events in a Prospective Study. | 2019 | Details |
| A09092 | 31880161 | Rev Esp Enferm Dig | Risk factors differentially associated with non-alcoholic fatty liver disease in males and females with metabolic syndrome. | 2020 | Details |
| A09125 | 31866269 | J Visc Surg | Metabolic syndrome and hepatic surgery. | 2019 | Details |
| A09127 | 31865317 | Dig Dis | Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. | 2019 | Details |
| A09130 | 31863731 | Exp Neurol | Hepatic dysfunction after spinal cord injury: A vicious cycle of central and peripheral pathology? | 2019 | Details |
| A09139 | 31861497 | Nutrients | Protective Effect of α-Linolenic Acid on Non-Alcoholic Hepatic Steatosis and Interleukin-6 and -10 in Wistar Rats. | 2019 | Details |
| A09161 | 31852444 | BMC Gastroenterol | Effects of alternate-day fasting on body weight and dyslipidaemia in patients with non-alcoholic fatty liver disease: a randomised controlled trial. | 2019 | Details |
| A09165 | 31851849 | Scand J Clin Lab Invest | Metabolic syndrome but not genetic polymorphisms known to induce NAFLD predicts increased total mortality in subjects with NAFLD (OPERA study). | 2019 | Details |
| A09176 | 31847199 | Nutrients | Moderate Alcohol Intake in Non-Alcoholic Fatty Liver Disease: To Drink or Not to Drink? | 2019 | Details |
| A09199 | 31838198 | Prostaglandins Other Lipid Mediat | Cd36 gene expression in adipose and hepatic tissue mediates the lipids accumulation in liver of obese rats with sucrose-induced hepatic steatosis. | 2019 | Details |
| A09215 | 31833859 | Am J Gastroenterol | Disease Severity Is Associated With Higher Healthcare Utilization in Nonalcoholic Steatohepatitis Medicare Patients. | 2020 | Details |
| A09232 | 31826069 | J Gastrointestin Liver Dis | PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes. | 2019 | Details |
| A09239 | 31822739 | Sci Rep | Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling. | 2019 | Details |
| A09243 | 31820847 | Liver Int | Associations of subclinical atherosclerosis with nonalcoholic fatty liver disease and fibrosis assessed by non-invasive score. | 2019 | Details |
| A09250 | 31817623 | J Clin Med | Higher Sodium Intake Assessed by 24 Hour Urinary Sodium Excretion Is Associated with Non-Alcoholic Fatty Liver Disease: The PREVEND Cohort Study. | 2019 | Details |
| A09259 | 31814783 | Hepat Med | A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A09263 | 31813265 | Antioxid Redox Signal | Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation. | 2020 | Details |
| A09282 | 31806905 | Nat Med | Chronic inflammation in the etiology of disease across the life span. | 2019 | Details |
| A09287 | 31805072 | PLoS One | Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Leprdb/J mouse model of non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A09299 | 31800606 | PLoS One | ABO blood group and risk of newly diagnosed nonalcoholic fatty liver disease: A case-control study in Han Chinese population. | 2019 | Details |
| A09305 | 31797589 | Pac Symp Biocomput | Automated phenotyping of patients with non-alcoholic fatty liver disease reveals clinically relevant disease subtypes. | 2020 | Details |
| A09307 | 31797186 | Dig Dis Sci | Impact of NAFLD on the Incidence of Cardiovascular Diseases in a Primary Care Population in Germany. | 2019 | Details |
| A09329 | 31789677 | Curr Opin Lipidol | Fatty liver, cardiometabolic disease and mortality. | 2020 | Details |
| A09330 | 31789009 | Minerva Cardioangiol | The association between non-alcoholic fatty liver disease and valvular heart disease. | 2019 | Details |
| A09335 | 31786361 | Diabetes Metab | Screening for non-alcoholic fatty liver disease using liver stiffness measurement and its association with chronic kidney disease and cardiovascular complications in patients with type 2 diabetes. | 2019 | Details |
| A09348 | 31782543 | Aliment Pharmacol Ther | The impact of modifiable risk factors on the long-term outcomes of non-alcoholic fatty liver disease. | 2019 | Details |
| A09372 | 31773475 | Eur J Epidemiol | Circulating total bilirubin and risk of non-alcoholic fatty liver disease in the PREVEND study: observational findings and a Mendelian randomization study. | 2019 | Details |
| A09384 | 31767252 | Presse Med | [Pathogenesis of non-alcoholic fatty liver disease]. | 2019 | Details |
| A09415 | 31757735 | Presse Med | [Pharmacological treatment of NASH]. | 2019 | Details |
| A09420 | 31756645 | Cytokine | Leptin/adiponectin ratio correlates with hepatic steatosis but not arterial stiffness in nonalcoholic fatty liver disease in Japanese population. | 2019 | Details |
| A09429 | 31753536 | Mayo Clin Proc | Prevalence and Impact of Nonalcoholic Fatty Liver Disease in Atrial Fibrillation. | 2019 | Details |
| A09441 | 31749300 | Liver Int | Liver stiffness measurement predicts long-term survival and complications in non-alcoholic fatty liver disease. | 2019 | Details |
| A09462 | 31734987 | Zhonghua Gan Zang Bing Za Zhi | [Expert recommendations on standardized diagnosis and treatment for fatty liver disease in China (2019 revised edition)]. | 2019 | Details |
| A09465 | 31734402 | Autoimmun Rev | Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies. | 2019 | Details |
| A09469 | 31731527 | Nutrients | Altilix® Supplement Containing Chlorogenic Acid and Luteolin Improved Hepatic and Cardiometabolic Parameters in Subjects with Metabolic Syndrome: A 6 Month Randomized, Double-Blind, Placebo-Controlled Study. | 2019 | Details |
| A09492 | 31724099 | Dig Dis Sci | Early Predictors of Cardiovascular Disease Risk in Nonalcoholic Fatty Liver Disease: Non-obese Versus Obese Patients. | 2019 | Details |
| A09517 | 31713012 | Diabetologia | Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. | 2019 | Details |
| A09529 | 31706690 | Trends Endocrinol Metab | Immunoregulatory Functions of Nuclear Receptors: Mechanisms and Therapeutic Implications. | 2019 | Details |
| A09530 | 31706246 | Environ Toxicol Pharmacol | Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis. | 2019 | Details |
| A09533 | 31705824 | Hepatology | Patatin-Like Phospholipase Domain-Containing Protein 3 I148M and Liver Fat and Fibrosis Scores Predict Liver Disease Mortality in the U.S. Population. | 2020 | Details |
| A09543 | 31701071 | Hepatol Commun | Cardiovascular Risk Categories in Patients With Nonalcoholic Fatty Liver Disease and the Role of Low-Density Lipoprotein Cholesterol. | 2019 | Details |
| A09544 | 31701070 | Hepatol Commun | Mortality Related to Nonalcoholic Fatty Liver Disease Is Increasing in the United States. | 2019 | Details |
| A09556 | 31695252 | J Clin Exp Hepatol | Preventive Strategies for Nonalcoholic Fatty Liver Disease After Liver Transplantation. | 2019 | Details |
| A09557 | 31695251 | J Clin Exp Hepatol | Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A09567 | 31692530 | Pediatric Health Med Ther | Pediatric non-alcoholic fatty liver disease: current perspectives on diagnosis and management. | 2019 | Details |
| A09573 | 31690988 | Diabetologia | Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation. | 2019 | Details |
| A09583 | 31686884 | Diabetes Metab Syndr Obes | Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors: A Clinician's Guide. | 2019 | Details |
| A09584 | 31686762 | World J Gastroenterol | Ultrasound-based techniques for the diagnosis of liver steatosis. | 2019 | Details |
| A09585 | 31686320 | Sci China Life Sci | Regulation of glucose and lipid metabolism in health and disease. | 2019 | Details |
| A09591 | 31682643 | Frontline Gastroenterol | A multidisciplinary approach to the management of NAFLD is associated with improvement in markers of liver and cardio-metabolic health. | 2019 | Details |
| A09594 | 31682518 | Endocr Pract | CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS - EXECUTIVE SUMMARY. | 2019 | Details |
| A09612 | 31675274 | Metab Syndr Relat Disord | Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection. | 2019 | Details |
| A09620 | 31672448 | Metabolism | Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box! | 2019 | Details |
| A09650 | 31658974 | Diabetes Care | Economic and Clinical Burden of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes in the U.S. | 2019 | Details |
| A09669 | 31652761 | Nutrients | Obesity in the Liver Transplant Setting. | 2019 | Details |
| A09695 | 31644993 | J Neurol Sci | Association between nonalcoholic fatty liver disease with advanced fibrosis and stroke. | 2019 | Details |
| A09699 | 31641249 | Nat Rev Gastroenterol Hepatol | Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology. | 2019 | Details |
| A09714 | 31635469 | Vnitr Lek | Serum markers in diagnostics of steatohepatitis. | 2019 | Details |
| A09720 | 31634532 | J Hepatol | Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis. | 2019 | Details |
| A09721 | 31634357 | PLoS One | Modeling the natural history of fatty liver using lifestyle-related risk factors: Effects of body mass index (BMI) on the life-course of fatty liver. | 2019 | Details |
| A09738 | 31630897 | Trends Endocrinol Metab | NAFLD and Atherosclerosis: Two Sides of the Same Dysmetabolic Coin? | 2019 | Details |
| A09743 | 31629366 | Endocr Rev | Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management. | 2020 | Details |
| A09759 | 31622202 | Curr Drug Deliv | Protective Effects of Incretin Against Age-Related Diseases. | 2019 | Details |
| A09761 | 31620652 | Transl Gastroenterol Hepatol | Effect of alcohol consumption on nonalcoholic fatty liver disease. | 2019 | Details |
| A09762 | 31620647 | Transl Gastroenterol Hepatol | Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations. | 2019 | Details |
| A09770 | 31616668 | Front Med (Lausanne) | Cardiovascular Risk in Fatty Liver Disease: The Liver-Heart Axis-Literature Review. | 2019 | Details |
| A09774 | 31614690 | Int J Mol Sci | Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence. | 2019 | Details |
| A09782 | 31612634 | Liver Int | Liver fibrosis by FibroScan® independently of established cardiovascular risk parameters associates with macrovascular and microvascular complications in patients with type 2 diabetes. | 2019 | Details |
| A09789 | 31610081 | Liver Transpl | Nonalcoholic Steatohepatitis After Liver Transplantation. | 2019 | Details |
| A09794 | 31608220 | J Clin Transl Hepatol | Obesity Paradox in Chronic Liver Diseases: Product of Bias or a Real Thing? | 2019 | Details |
| A09803 | 31604171 | Atherosclerosis | Visceral adipose tissue volume is associated with premature atherosclerosis in early type 2 diabetes mellitus independent of traditional risk factors. | 2019 | Details |
| A09811 | 31601229 | Trials | Effect of probiotic supplementation in nonalcoholic steatohepatitis patients: PROBILIVER TRIAL protocol. | 2019 | Details |
| A09812 | 31601203 | BMC Endocr Disord | Prevalence of cardiovascular risk factors in non-menopausal and postmenopausal inpatients with type 2 diabetes mellitus in China. | 2019 | Details |
| A09834 | 31595236 | Porto Biomed J | Dietary cholesterol does not break your heart but kills your liver. | 2019 | Details |
| A09836 | 31594780 | BMJ | Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. | 2019 | Details |
| A09879 | 31577570 | Am J Gastroenterol | Women With Nonalcoholic Fatty Liver Disease Lose Protection Against Cardiovascular Disease: A Longitudinal Cohort Study. | 2019 | Details |
| A09883 | 31575467 | Ann Hepatol | Evaluation of thrombocytopenia in patients with non-alcoholic fatty liver disease without cirrhosis. | 2019 | Details |
| A09899 | 31568800 | J Hepatol | Hepatocyte-derived extracellular vesicles promote endothelial inflammation and atherogenesis via microRNA-1. | 2019 | Details |
| A09922 | 31559105 | World J Gastrointest Pathophysiol | Overview of studies of the vitamin D/vitamin D receptor system in the development of non-alcoholic fatty liver disease. | 2019 | Details |
| A09933 | 31554932 | Nat Rev Endocrinol | The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state. | 2019 | Details |