Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03183 | 34096925 | J Vis Exp | A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium. | 2021 | Details |
| A03185 | 34096005 | Methods Mol Biol | Protocols for Mitochondria as the Target of Pharmacological Therapy in the Context of Nonalcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A03203 | 34091049 | Clin Gastroenterol Hepatol | A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores. | 2021 | Details |
| A03204 | 34091047 | Clin Gastroenterol Hepatol | The Placebo Response in Randomized Trials in Nonalcoholic Steatohepatitis Simply Explained. | 2021 | Details |
| A03205 | 34090928 | J Hepatol | Long-term outcomes and predictive ability of non-invasive scoring systems in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A03206 | 34090052 | Biomed Pharmacother | Probiotic-prebiotic-synbiotic modulation of (YAP1, LATS1 and NF2 mRNAs/miR-1205/lncRNA SRD5A3-AS1) panel in NASH animal model. | 2021 | Details |
| A03209 | 34088912 | Sci Rep | A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models. | 2021 | Details |
| A03211 | 34088709 | BMJ Open | Is there scope to improve the selection of patients with alcohol-related liver disease for referral to secondary care? A retrospective analysis of primary care referrals to a UK liver centre, incorporating simple blood tests. | 2021 | Details |
| A03215 | 34087329 | Adv Drug Deliv Rev | Role of extracellular vesicles in liver diseases and their therapeutic potential. | 2021 | Details |
| A03216 | 34086626 | J Clin Psychopharmacol | Risk of Nonalcoholic Fatty Liver Disease in Patients With Schizophrenia Treated With Antipsychotic Drugs: A Cross-sectional Study. | 2021 | Details |
| A03218 | 34083571 | Sci Rep | High FIB4 index is an independent risk factor of diabetic kidney disease in type 2 diabetes. | 2021 | Details |
| A03221 | 34082056 | Diabetes Res Clin Pract | Feasibility and efficiency of European guidelines for NAFLD assessment in patients with type 2 diabetes: A prospective study. | 2021 | Details |
| A03222 | 34082054 | Diabetes Res Clin Pract | Significant liver fibrosis, as assessed by fibroscan, is independently associated with chronic vascular complications of type 2 diabetes: A multicenter study. | 2021 | Details |
| A03224 | 34081733 | PLoS One | Prevalence and factors associated with NAFLD detected by vibration controlled transient elastography among US adults: Results from NHANES 2017-2018. | 2021 | Details |
| A03226 | 34081289 | Hepatol Int | Histological severity of nonalcoholic fatty liver disease is associated with 10-year risk for atherosclerotic cardiovascular disease. | 2021 | Details |
| A03228 | 34080327 | J Cachexia Sarcopenia Muscle | Non-alcoholic fatty liver disease and sarcopenia additively increase mortality: a Korean nationwide survey. | 2021 | Details |
| A03230 | 34079318 | Diabetes Metab Syndr Obes | Association Between Thyroid Hormone Levels and Advanced Liver Fibrosis in Patients with Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A03234 | 34077628 | United European Gastroenterol J | High liver stiffness values by transient elastography related to metabolic syndrome and harmful alcohol use in a large Spanish cohort. | 2021 | Details |
| A03235 | 34077443 | PLoS One | Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes. | 2021 | Details |
| A03236 | 34076851 | Hepatol Int | Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease. | 2021 | Details |
| A03248 | 34072586 | Int J Mol Sci | One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver. | 2021 | Details |
| A03249 | 34072480 | J Clin Med | FibroTest for Evaluating Fibrosis in Non-Alcoholic Fatty Liver Disease Patients: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A03254 | 34069568 | Nutrients | Dynamics of Serum Retinol and Alpha-Tocopherol Levels According to Non-Alcoholic Fatty Liver Disease Status. | 2021 | Details |
| A03256 | 34069176 | Life (Basel) | Kaempferol-3-O-Glucuronide Ameliorates Non-Alcoholic Steatohepatitis in High-Cholesterol-Diet-Induced Larval Zebrafish and HepG2 Cell Models via Regulating Oxidation Stress. | 2021 | Details |
| A03259 | 34068699 | J Clin Med | Diabetic Kidney Disease, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease: A New Triumvirate? | 2021 | Details |
| A03263 | 34067076 | Cancers (Basel) | The Effect of Diffuse Liver Diseases on the Occurrence of Liver Metastases in Cancer Patients: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A03264 | 34065978 | Nutrients | PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. | 2021 | Details |
| A03266 | 34065331 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease (NAFLD). Mitochondria as Players and Targets of Therapies? | 2021 | Details |
| A03272 | 34064999 | Cancers (Basel) | Biomarkers of Oncogenesis, Adipose Tissue Dysfunction and Systemic Inflammation for the Detection of Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03273 | 34064988 | Cancers (Basel) | The FIB-4 Index Is a Useful Predictor for the Development of Hepatocellular Carcinoma in Patients with Coexisting Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B. | 2021 | Details |
| A03275 | 34064387 | Cells | Psoriasis and Liver Damage in HIV-Infected Patients. | 2021 | Details |
| A03277 | 34064337 | J Clin Med | Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity. | 2021 | Details |
| A03281 | 34062584 | Dtsch Med Wochenschr | [Alpha-1 antitrypsin deficiency: cause and cofactor for liver disease]. | 2021 | Details |
| A03284 | 34061469 | J Cachexia Sarcopenia Muscle | Ectopic fat in liver and skeletal muscle is associated with shorter overall survival in patients with colorectal liver metastases. | 2021 | Details |
| A03289 | 34059612 | Curr Opin Cardiol | Update on cardiovascular risk in nonalcoholic fatty liver disease. | 2021 | Details |
| A03290 | 34058299 | Diabetes Res Clin Pract | Current type 2 diabetes, rather than previous gestational diabetes, is associated with liver disease in U.S. Women. | 2021 | Details |
| A03291 | 34058224 | Metabolism | Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1. | 2021 | Details |
| A03296 | 34056769 | Phytother Res | Molecular updates on berberine in liver diseases: Bench to bedside. | 2021 | Details |
| A03303 | 34051282 | Diabetes Res Clin Pract | Impact of diabetes on subclinical atherosclerosis and major cardiovascular events in individuals with and without non-alcoholic fatty liver disease. | 2021 | Details |
| A03306 | 34051052 | Liver Int | Collagen proportionate area correlates with histological stage and predicts clinical events in primary sclerosing cholangitis. | 2021 | Details |
| A03307 | 34050922 | Eur J Clin Invest | Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship. | 2021 | Details |
| A03317 | 34047448 | Mol Nutr Food Res | Soyasaponin A2 Alleviates Steatohepatitis Possibly through Regulating Bile Acids and Gut Microbiota in the Methionine and Choline-Deficient (MCD) Diet-induced Nonalcoholic Steatohepatitis (NASH) Mice. | 2021 | Details |
| A03320 | 34046333 | Pediatr Gastroenterol Hepatol Nutr | Hepcidin Levels and Pathological Characteristics in Children with Fatty Liver Disease. | 2021 | Details |
| A03325 | 34043691 | PLoS One | Evaluation of non-alcoholic fatty liver disease in patients with inflammatory bowel disease using controlled attenuation parameter technology: A Taiwanese retrospective cohort study. | 2021 | Details |
| A03331 | 34041187 | J Family Med Prim Care | Number needed to screen to prevent progression of liver fibrosis to cirrhosis at primary health centers: An experience from Delhi. | 2021 | Details |
| A03334 | 34040322 | World J Gastroenterol | Individualized treatment options for patients with non-cirrhotic and cirrhotic liver disease. | 2021 | Details |
| A03339 | 34036255 | JHEP Rep | Historical narrative from fatty liver in the nineteenth century to contemporary NAFLD - Reconciling the present with the past. | 2021 | Details |
| A03344 | 34033923 | Clin Gastroenterol Hepatol | Differential Clinical Characteristics and Mortality Outcomes in Persons With NAFLD and/or MAFLD. | 2021 | Details |
| A03348 | 34032730 | Medicine (Baltimore) | Acupuncture for type 2 diabetes mellitus with nonalcoholic fatty liver disease: A protocol for systematic review and meta-analysis. | 2021 | Details |
| A03350 | 34032030 | J Korean Med Sci | Severe Phenotype of Non-alcoholic Fatty Liver Disease in Pediatric Patients with Subclinical Hypothyroidism: a Retrospective Multicenter Study from Korea. | 2021 | Details |
| A03351 | 34031913 | J Gastroenterol Hepatol | TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy-proven nonalcoholic fatty liver disease. | 2021 | Details |
| A03352 | 34031802 | Dig Dis Sci | Comorbidities Are Associated with Fibrosis in NAFLD Subjects: A Nationwide Study (NASH-CO Study). | 2021 | Details |
| A03354 | 34031327 | Med J Malaysia | Liver fibrosis associated with adipose tissue and liver inflammation in an obesity model. | 2021 | Details |
| A03360 | 34028753 | Methods Mol Biol | Mouse Models of Liver Fibrosis. | 2021 | Details |
| A03361 | 34027933 | Minerva Gastroenterol (Torino) | The role of elastography in non-alcoholic fatty liver disease. | 2021 | Details |
| A03362 | 34027591 | Dig Dis Sci | Hepatocellular Carcinoma in Patients Without Cirrhosis: The Fibrosis Stage Distribution, Characteristics and Survival. | 2021 | Details |
| A03363 | 34027561 | Arch Toxicol | Infections at the nexus of metabolic-associated fatty liver disease. | 2021 | Details |
| A03367 | 34027269 | Hepatol Commun | Relationship of ELF and PIIINP With Liver Histology and Response to Vitamin E or Pioglitazone in the PIVENS Trial. | 2021 | Details |
| A03368 | 34027267 | Hepatol Commun | SOMAscan Proteomics Identifies Serum Biomarkers Associated With Liver Fibrosis in Patients With NASH. | 2021 | Details |
| A03372 | 34027109 | Clin Exp Hepatol | Non-alcoholic fatty liver disease and lipotoxicity. | 2021 | Details |
| A03387 | 34020377 | Comput Methods Programs Biomed | Training of computational algorithms to predict NAFLD activity score and fibrosis stage from liver histopathology slides. | 2021 | Details |
| A03390 | 34019560 | PLoS One | Modelling the cost effectiveness of non-alcoholic fatty liver disease risk stratification strategies in the community setting. | 2021 | Details |
| A03392 | 34019202 | Mol Cell Biochem | New insights into BMP9 signaling in liver diseases. | 2021 | Details |
| A03397 | 34016882 | J Pediatr Gastroenterol Nutr | Transient Elastography in Pediatric Liver Disease. | 2021 | Details |
| A03403 | 34014450 | Hepatol Int | Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice. | 2021 | Details |
| A03406 | 34013366 | Int J Mol Med | Histone deacetylase‑2: A potential regulator and therapeutic target in liver disease (Review). | 2021 | Details |
| A03407 | 34013171 | iScience | Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease. | 2021 | Details |
| A03410 | 34011624 | BMJ Open Gastroenterol | Uncovering undiagnosed liver disease: prevalence and opportunity for intervention in a population attending colonoscopy. | 2021 | Details |
| A03416 | 34007801 | J Clin Transl Hepatol | Associations of Hydroxysteroid 17-beta Dehydrogenase 13 Variants with Liver Histology in Chinese Patients with Metabolic-associated Fatty Liver Disease. | 2021 | Details |
| A03417 | 34007325 | Exp Ther Med | Maternal obesity accelerated non-alcoholic fatty liver disease in offspring mice by reducing autophagy. | 2021 | Details |
| A03419 | 34007127 | World J Gastroenterol | Non-alcoholic fatty liver and chronic kidney disease: Retrospect, introspect, and prospect. | 2021 | Details |
| A03421 | 34006921 | Sci Rep | Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach. | 2021 | Details |
| A03422 | 34006273 | BMC Endocr Disord | Correlational study on the levels of 25-hydroxyvitamin D and non-alcoholic fatty liver disease in type 2 diabetic patients. | 2021 | Details |
| A03427 | 34003729 | Am J Respir Cell Mol Biol | Hepatocyte HIF-1 and Intermittent Hypoxia Independently Impact Liver Fibrosis in Murine Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03428 | 34002481 | Kaohsiung J Med Sci | Gamma-glutamyl transpeptidase elevation is associated with metabolic syndrome, hepatic steatosis, and fibrosis in patients with nonalcoholic fatty liver disease: A community-based cross-sectional study. | 2021 | Details |
| A03432 | 34002097 | Nat Metab | UCP1 governs liver extracellular succinate and inflammatory pathogenesis. | 2021 | Details |
| A03433 | 34002001 | Sci Rep | Serum iron and risk of nonalcoholic fatty liver disease and advanced hepatic fibrosis in US adults. | 2021 | Details |
| A03434 | 34001645 | Gut | Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis. | 2021 | Details |
| A03441 | 33999371 | Eat Weight Disord | The predictive role of parathyroid hormone for non-alcoholic fatty liver disease based on invasive and non-invasive findings in candidates of bariatric surgery. | 2021 | Details |
| A03443 | 33998102 | Hepatol Res | Myostatin as a fibroblast-activating factor impacts on postoperative outcome in patients with hepatocellular carcinoma. | 2021 | Details |
| A03451 | 33995271 | Front Endocrinol (Lausanne) | Pioglitazone for NAFLD Patients With Prediabetes or Type 2 Diabetes Mellitus: A Meta-Analysis. | 2021 | Details |
| A03452 | 33994867 | Int J Biol Sci | MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03467 | 33991635 | J Hepatol | Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis. | 2021 | Details |
| A03468 | 33991615 | Cell Signal | Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathway. | 2021 | Details |
| A03469 | 33991468 | Biomol Concepts | Myosteatosis in NAFLD patients correlates with plasma Cathepsin D. | 2021 | Details |
| A03470 | 33991461 | Physiol Rep | Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice. | 2021 | Details |
| A03473 | 33991378 | J Magn Reson Imaging | Assessment of Imaging Modalities Against Liver Biopsy in Nonalcoholic Fatty Liver Disease: The Amsterdam NAFLD-NASH Cohort. | 2021 | Details |
| A03478 | 33989548 | Cell | Mechanisms and disease consequences of nonalcoholic fatty liver disease. | 2021 | Details |
| A03479 | 33989346 | PLoS One | Is there a role for neuregulin 4 in human nonalcoholic fatty liver disease? | 2021 | Details |
| A03482 | 33987427 | Ann Transl Med | Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention. | 2021 | Details |
| A03485 | 33987359 | Ann Transl Med | ENO3 promoted the progression of NASH by negatively regulating ferroptosis via elevation of GPX4 expression and lipid accumulation. | 2021 | Details |
| A03489 | 33985827 | Ultrasound Med Biol | Diagnostic Performance of 2-D Shear-Wave Elastography with Propagation Maps and Attenuation Imaging in Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A03495 | 33983444 | Nephrol Dial Transplant | Role of non-alcoholic fatty liver disease in the evolution of renal function in patients with diabetes mellitus. | 2022 | Details |
| A03499 | 33982243 | Obes Surg | Correlation Between Anthropometric Measurements and Non-alcoholic Fatty Liver Disease in Individuals With Obesity Undergoing Bariatric Surgery: Cross-Sectional Study. | 2021 | Details |
| A03502 | 33979963 | Zhonghua Gan Zang Bing Za Zhi | [Comparative study of clinicopathological features, and risk factors of advanced fibrosis between genders with non-alcoholic fatty liver disease]. | 2021 | Details |
| A03507 | 33977953 | Food Funct | Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD. | 2021 | Details |
| A03512 | 33975381 | Aliment Pharmacol Ther | The impact of genetic risk on liver fibrosis in non-alcoholic fatty liver disease as assessed by magnetic resonance elastography. | 2021 | Details |
| A03519 | 33972770 | Nat Rev Gastroenterol Hepatol | The complex link between NAFLD and type 2 diabetes mellitus - mechanisms and treatments. | 2021 | Details |
| A03524 | 33970131 | J Vis Exp | Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH. | 2021 | Details |
| A03530 | 33967185 | Endocr J | Role of chronic inflammation in the pathogenesis of nonalcoholic steatohepatitis: lessons from a unique mouse model using melanocortin receptor-deficient mice. | 2021 | Details |