Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A51808 | 33962074 | Cell Mol Gastroenterol Hepatol | Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases. | 2021 | Details |
| A51814 | 33946738 | Cells | Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity. | 2021 | Details |
| A51817 | 33941552 | BMJ Open Diabetes Res Care | Antidiabetic E4orf1 protein prevents hepatic steatosis and reduces markers of aging-related cellular damage in high fat fed older mice. | 2021 | Details |
| A51824 | 33911888 | Diabetes Metab Syndr Obes | Association Between Metabolic Associated Fatty Liver Disease and Chronic Kidney Disease: A Cross-Sectional Study from NHANES 2017-2018. | 2021 | Details |
| A51825 | 33911465 | World J Gastroenterol | Lipotoxic hepatocyte-derived exosomal miR-1297 promotes hepatic stellate cell activation through the PTEN signaling pathway in metabolic-associated fatty liver disease. | 2021 | Details |
| A51827 | 33894105 | Liver Int | Maternal nicotine exposure aggravates metabolic associated fatty liver disease via PI3K/Akt signaling in adult offspring mice. | 2021 | Details |
| A51832 | 33840726 | Am J Gastroenterol | Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B. | 2021 | Details |
| A51833 | 33833761 | Front Immunol | Hepatic Dendritic Cells in the Development and Progression of Metabolic Steatohepatitis. | 2021 | Details |
| A51834 | 33833481 | World J Gastroenterol | Metabolic complications of hepatitis C virus infection. | 2021 | Details |
| A51835 | 33829726 | Minerva Gastroenterol (Torino) | The effects of dietary intervention on fibrosis and biochemical parameters in metabolic-associated fatty liver disease. | 2021 | Details |
| A51837 | 33809061 | Cells | Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge. | 2021 | Details |
| A51857 | 33640795 | EBioMedicine | The KLB rs17618244 gene variant is associated with fibrosing MAFLD by promoting hepatic stellate cell activation. | 2021 | Details |
| A51860 | 33604256 | J Clin Transl Hepatol | An Update on Efficacy and Safety of Emerging Hepatic Antifibrotic Agents. | 2021 | Details |
| A51865 | 33584066 | World J Gastroenterol | Clinic-pathological features of metabolic associated fatty liver disease with hepatitis B virus infection. | 2021 | Details |
| A51871 | 33542668 | Nat Sci Sleep | Circadian Misalignment Rather Than Sleep Duration is Associated with MAFLD: A Population-Based Propensity Score-Matched Study. | 2021 | Details |
| A51876 | 33508843 | Dig Dis | Early Kidney Dysfunction in Metabolic-Associated Fatty Liver Disease: Is Transient Elastography Useful as a Screening Method? | 2021 | Details |
| A51880 | 33490096 | Front Med (Lausanne) | Macrophage Activation Markers, Soluble CD163 and Mannose Receptor, in Liver Fibrosis. | 2021 | Details |
| A51890 | 33436764 | Sci Rep | Microbiota analysis and transient elastography reveal new extra-hepatic components of liver steatosis and fibrosis in obese patients. | 2021 | Details |
| A51894 | 35782891 | Hepatol Forum | High incidence of hepatitis B core antibody positivity in metabolic-associated fatty liver disease-related cirrhosis. | 2021 | Details |
| A51904 | 33323476 | Diabetes Care | Presence of Liver Steatosis Is Associated With Greater Diabetes Remission After Gastric Bypass Surgery. | 2020 | Details |
| A51906 | 33306709 | PLoS One | Genetic variation in the TLL1 gene is not associated with fibrosis in patients with metabolic associated fatty liver disease. | 2020 | Details |
| A51913 | 33291840 | Animals (Basel) | Administration of Protein Hydrolysates from Anchovy (Engraulis Encrasicolus) Waste for Twelve Weeks Decreases Metabolic Dysfunction-Associated Fatty Liver Disease Severity in ApoE-/-Mice. | 2020 | Details |
| A51918 | 33244194 | World J Gastroenterol | Efficacy and safety of anti-hepatic fibrosis drugs. | 2020 | Details |
| A51926 | 33170807 | JCI Insight | Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease. | 2020 | Details |
| A51935 | 33083279 | Liver Cancer | Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. | 2020 | Details |
| A51950 | 32973993 | Ther Adv Endocrinol Metab | Insufficient nocturnal sleep was associated with a higher risk of fibrosis in patients with diabetes with metabolic associated fatty liver disease. | 2020 | Details |
| A51954 | 32937022 | Liver Int | Concerning 'Liver steatosis is highly prevalent and is associated with metabolic risk factors and liver fibrosis in adult patients with type 1 Gaucher disease' by Nascimbeni et al. | 2021 | Details |
| A51974 | 32705906 | Expert Rev Gastroenterol Hepatol | MAFLD in COVID-19 patients: an insidious enemy. | 2020 | Details |
| A51978 | 32663609 | Biochim Biophys Acta Mol Cell Biol Lipids | Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD. | 2020 | Details |
| A51981 | 32633236 | J Physiol Pharmacol | COVID-19 - more than respiratory disease: a gastroenterologist's perspective. | 2020 | Details |
| A52006 | 32424181 | Sci Rep | Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential? | 2020 | Details |
| A52007 | 32408016 | Mol Metab | Suppressing adipocyte inflammation promotes insulin resistance in mice. | 2020 | Details |
| A52019 | 32231246 | Cell Death Differ | OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. | 2020 | Details |
| A52021 | 32219872 | Hepatology | Hydrogen Sulfide Alleviates Liver Injury Through the S-Sulfhydrated-Kelch-Like ECH-Associated Protein 1/Nuclear Erythroid 2-Related Factor 2/Low-Density Lipoprotein Receptor-Related Protein 1 Pathway. | 2021 | Details |
| A52051 | 31888144 | Int J Mol Sci | Altered Metabolic Profile and Adipocyte Insulin Resistance Mark Severe Liver Fibrosis in Patients with Chronic Liver Disease. | 2019 | Details |
| A52057 | 31813960 | Hum Mol Genet | Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels. | 2020 | Details |
| A52065 | 31698809 | J Clin Med | Insulin Resistance Associated Disorders Pivoting Long-Term Hepatitis B Surface Antigen Decline During Entecavir Therapy. | 2019 | Details |
| A52082 | 31559327 | GE Port J Gastroenterol | Fatty Liver and Autoimmune Hepatitis: Two Forms of Liver Involvement in Lipodystrophies. | 2019 | Details |
| A52101 | 31243135 | J Virol | Transforming Growth Factor β Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections. | 2019 | Details |
| A52107 | 31121167 | Gastroenterology | Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation. | 2019 | Details |
| A52111 | 31091179 | Viral Immunol | Hepatic Expression of Phosphorylated Kinase Akt and Glycogen Synthase Kinase-3 Isoforms in Patients with Chronic Hepatitis C. | 2019 | Details |
| A52122 | 30979683 | J Cyst Fibros | Cystic fibrosis dyslipidaemia: A cross-sectional study. | 2019 | Details |
| A52133 | 30895682 | J Viral Hepat | Fibrosis evolution in chronic hepatitis B e antigen-negative patients across a 10-year interval. | 2019 | Details |
| A52167 | 30476128 | J Clin Endocrinol Metab | Postmortem Findings in a Young Man With Congenital Generalized Lipodystrophy, Type 4 Due to CAVIN1 Mutations. | 2019 | Details |
| A52174 | 30423963 | Nutrients | Ursolic Acid Attenuates Hepatic Steatosis, Fibrosis, and Insulin Resistance by Modulating the Circadian Rhythm Pathway in Diet-Induced Obese Mice. | 2018 | Details |
| A52175 | 30418544 | Cardiovasc Res | Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure. | 2019 | Details |
| A52191 | 30282988 | Sci Rep | Maternal high-fat diet consumption induces sex-dependent alterations of the endocannabinoid system and redox homeostasis in liver of adult rat offspring. | 2018 | Details |
| A52202 | 30148105 | Indian J Endocrinol Metab | The Twin White Herrings: Salt and Sugar. | 2020 | Details |
| A52205 | 30132924 | Alcohol Clin Exp Res | A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease. | 2018 | Details |
| A52213 | 30049588 | Nutr Res | The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome. | 2018 | Details |
| A52215 | 30032428 | Diabetologia | A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes. | 2018 | Details |
| A52231 | 29897997 | PLoS One | The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life. | 2018 | Details |
| A52243 | 29768198 | Cell Rep | Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis. | 2018 | Details |
| A52245 | 29746485 | PLoS One | Adiponectin and the steatosis marker Chi3L1 decrease following switch to raltegravir compared to continued PI/NNRTI-based antiretroviral therapy. | 2018 | Details |
| A52268 | 29454750 | Am J Pathol | A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84. | 2018 | Details |
| A52269 | 29453696 | Heart Fail Rev | Interrelationship between diabetes mellitus and heart failure: the role of peroxisome proliferator-activated receptors in left ventricle performance. | 2018 | Details |
| A52285 | 29216341 | ILAR J | Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field. | 2017 | Details |
| A52297 | 28969178 | J Clin Diagn Res | Association of Serum Lipids with Hepatic Steatosis, Stage of Liver Fibrosis and Viral Load in Chronic Hepatitis C. | 2017 | Details |
| A52305 | 28839198 | Sci Rep | The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis. | 2017 | Details |
| A52310 | 28811292 | Am J Physiol Endocrinol Metab | Dapagliflozin slows the progression of the renal and liver fibrosis associated with type 2 diabetes. | 2017 | Details |
| A52311 | 28810615 | Exp Ther Med | Detecting serum and urine metabolic profile changes of CCl4-liver fibrosis in rats at 12 weeks based on gas chromatography-mass spectrometry. | 2017 | Details |
| A52324 | 28614198 | Am J Surg Pathol | The Almost-Normal Liver Biopsy: Presentation, Clinical Associations, and Outcome. | 2017 | Details |
| A52328 | 28527666 | J Hepatol | Hepatic steatosis progresses faster in HIV mono-infected than HIV/HCV co-infected patients and is associated with liver fibrosis. | 2017 | Details |
| A52368 | 28100772 | J Biol Chem | De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis. | 2017 | Details |
| A52369 | 28099338 | Medicine (Baltimore) | Liver steatosis in children with chronic hepatitis B and C: Prevalence, predictors, and impact on disease progression. | 2017 | Details |
| A52373 | 28052632 | Liver Int | Impact of hepatitis C virus therapy on metabolism and public health. | 2017 | Details |
| A52385 | 27813205 | Genes Cells | Dietary fructose-induced hepatocellular carcinoma development manifested in mice lacking apoptosis inhibitor of macrophage (AIM). | 2016 | Details |
| A52389 | 27740738 | Liver Int | The prevalence of steatohepatitis in chronic hepatitis B patients and its impact on disease severity and treatment response. | 2016 | Details |
| A52394 | 27686501 | J Chin Med Assoc | Higher platelet counts are associated with metabolic syndrome independent of fatty liver diagnosis. | 2016 | Details |
| A52403 | 27568222 | EBioMedicine | Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control. | 2016 | Details |
| A52406 | 27540711 | J Pediatr Gastroenterol Nutr | Hepatic Inflammation May Influence Liver Stiffness Measurements by Transient Elastography in Children and Young Adults. | 2017 | Details |
| A52414 | 27368975 | J Inherit Metab Dis | Expanding the molecular diversity and phenotypic spectrum of glycerol 3-phosphate dehydrogenase 1 deficiency. | 2016 | Details |
| A52429 | 27209494 | Environ Health Prev Med | Importance of detoxifying enzymes in differentiating fibrotic development between SHRSP5/Dmcr and SHRSP rats. | 2016 | Details |
| A52503 | 26275081 | Eur J Gastroenterol Hepatol | Cardiovascular events in chronic hepatitis C: prognostic value of liver stiffness evolution. | 2015 | Details |
| A52506 | 26252914 | J Pediatr Gastroenterol Nutr | Clinical Features of Lysosomal Acid Lipase Deficiency. | 2015 | Details |
| A52525 | 26042203 | Mol Metab | Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. | 2015 | Details |
| A52545 | 25745813 | Gen Comp Endocrinol | Histomorphology of the bottlenose dolphin (Tursiops truncatus) pancreas and association of increasing islet β-cell size with chronic hypercholesterolemia. | 2015 | Details |
| A52554 | 25656826 | Trends Endocrinol Metab | Adipocytokines and hepatic fibrosis. | 2015 | Details |
| A52558 | 25632931 | Semin Liver Dis | MicroRNAs in fatty liver disease. | 2015 | Details |
| A52571 | 25486580 | J Mol Cell Cardiol | Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction. | 2014 | Details |
| A52580 | 25404244 | J Mol Med (Berl) | p53 in liver pathologies-taking the good with the bad. | 2014 | Details |
| A52584 | 25367448 | BMC Med | FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients. | 2014 | Details |
| A52605 | 25013400 | J Biomed Res | Rab proteins implicated in lipid storage and mobilization. | 2014 | Details |
| A52606 | 25003744 | Eur J Gastroenterol Hepatol | Sex-specific prevalence of fatty liver disease and associated metabolic factors in Wuhan, south central China. | 2014 | Details |
| A52612 | 24905107 | Z Gastroenterol | Prevalence of risk factors for liver disease in a random population sample in southern Germany. | 2014 | Details |
| A52618 | 24773203 | Alcohol Clin Exp Res | Modulation of fatty acid and bile acid metabolism by peroxisome proliferator-activated receptor α protects against alcoholic liver disease. | 2014 | Details |
| A52624 | 24659875 | World J Gastroenterol | Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. | 2014 | Details |
| A52645 | 24237940 | Liver Int | Non-invasive hepatic biomarkers (ELF and CK18) in people with type 2 diabetes: the Edinburgh type 2 diabetes study. | 2013 | Details |
| A52666 | 23941362 | Nutr J | Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial. | 2013 | Details |
| A52693 | 23445230 | Expert Rev Gastroenterol Hepatol | The predictive value of steatosis in hepatitis C virus infection. | 2013 | Details |
| A52695 | 23403242 | Mol Genet Metab | Histopathological findings in livers of patients with urea cycle disorders. | 2013 | Details |
| A52696 | 23398239 | Alcohol Clin Exp Res | Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis, and insulin sensitivity in mice. | 2013 | Details |
| A52705 | 23245234 | J Pharm Biomed Anal | Urinary metabonomics characterization of liver fibrosis induced by CCl₄ in rats and intervention effects of Xia Yu Xue Decoction. | 2012 | Details |
| A52719 | 22884994 | Toxicol Appl Pharmacol | Hepatic lipid profiling of deer mice fed ethanol using ¹H and ³¹P NMR spectroscopy: a dose-dependent subchronic study. | 2012 | Details |
| A52721 | 22829922 | PLoS One | Metabolite profiles reveal energy failure and impaired beta-oxidation in liver of mice with complex III deficiency due to a BCS1L mutation. | 2012 | Details |
| A52730 | 22719190 | World J Gastroenterol | Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis. | 2012 | Details |
| A52734 | 22664476 | J Clin Gastroenterol | Association of serum adipocytokines with insulin resistance and liver injury in patients with chronic hepatitis C genotype 4. | 2013 | Details |
| A52743 | 22508322 | Hepatology | Hepatic steatosis and steatohepatitis in human immunodeficiency virus/hepatitis C virus-coinfected patients. | 2012 | Details |
| A52754 | 22425495 | Int J Infect Dis | Prospective evaluation of hepatic steatosis in HIV-infected patients with or without hepatitis C virus co-infection. | 2012 | Details |
| A52767 | 22292946 | Liver Int | Early growth response-1 transcription factor promotes hepatic fibrosis and steatosis in long-term ethanol-fed Long-Evans rats. | 2012 | Details |