Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A03532 | 33966599 | Autophagy | Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death. | 2021 | Details |
A03536 | 33965477 | J Hepatol | Surveillance of patients with cirrhosis remains suboptimal in the United States. | 2021 | Details |
A03543 | 33962045 | Ann Hepatol | Assessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy. | 2021 | Details |
A03545 | 33961787 | Lancet Gastroenterol Hepatol | Non-alcoholic fatty liver disease: a multisystem disease requiring a multidisciplinary and holistic approach. | 2021 | Details |
A03549 | 33961302 | Hepatology | The Emerging Role of B Cells in the Pathogenesis of NAFLD. | 2021 | Details |
A03558 | 33955510 | Mol Med Rep | Parthenolide plays a protective role in the liver of mice with metabolic dysfunction‑associated fatty liver disease through the activation of the HIPPO pathway. | 2021 | Details |
A03563 | 33953582 | Diabetes Metab Syndr Obes | Correlation Between 25-Hydroxyvitamin D Level and Cardiac Diastolic Dysfunction in Chinese Adults with Early-Onset Type 2 Diabetes Mellitus: A Cross-Sectional Study. | 2021 | Details |
A03564 | 33952843 | Nihon Yakurigaku Zasshi | [The roles of gap junctional intercellular communication in non-alcoholic steatohepatitis (NASH) and liver fibrosis]. | 2021 | Details |
A03569 | 33951121 | J Gastrointestin Liver Dis | Association between Sarcopenic Obesity and Nonalcoholic Fatty Liver Disease and Fibrosis detected by Fibroscan. | 2021 | Details |
A03571 | 33950921 | Medicine (Baltimore) | Serum markers for predicting advanced fibrosis in patients with chronic hepatitis B and nonalcoholic fatty liver disease. | 2021 | Details |
A03572 | 33948987 | FASEB J | Porphyran-derived oligosaccharides alleviate NAFLD and related cecal microbiota dysbiosis in mice. | 2021 | Details |
A03580 | 33946377 | Medicina (Kaunas) | The Impact of Increased Fib-4 Score in Patients with Type II Diabetes Mellitus on Covid-19 Disease Prognosis. | 2021 | Details |
A03583 | 33943028 | J Diabetes Investig | Liver fibrosis is independently associated with diabetic peripheral neuropathy in type 2 diabetes mellitus. | 2021 | Details |
A03585 | 33941551 | BMJ Open Diabetes Res Care | Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels. | 2021 | Details |
A03587 | 33941179 | Biomed Eng Online | Viscoelasticity measured by shear wave elastography in a rat model of nonalcoholic fatty liver disease: comparison with dynamic mechanical analysis. | 2021 | Details |
A03592 | 33939147 | Dig Dis Sci | Impact of a Pilot Structured Mobile Technology Based Lifestyle Intervention for Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03593 | 33939118 | Drugs | Targeting AMPK by Statins: A Potential Therapeutic Approach. | 2021 | Details |
A03594 | 33938630 | Liver Int | Effects of intragastric balloon in patients with nonalcoholic fatty liver disease and advanced fibrosis. | 2021 | Details |
A03599 | 33937277 | Front Med (Lausanne) | Liver Fibrosis in Non-alcoholic Fatty Liver Disease: From Liver Biopsy to Non-invasive Biomarkers in Diagnosis and Treatment. | 2021 | Details |
A03600 | 33937257 | Front Cell Dev Biol | Autophagy in Hepatic Steatosis: A Structured Review. | 2021 | Details |
A03602 | 33935810 | Front Physiol | Serum Creatinine-to-Cystatin C Ratio in the Progression Monitoring of Non-alcoholic Fatty Liver Disease. | 2021 | Details |
A03609 | 33932956 | J Physiol | NAD+ and NAFLD - caution, causality and careful optimism. | 2021 | Details |
A03610 | 33932796 | Clin Nutr | Beverages and Non-alcoholic fatty liver disease (NAFLD): Think before you drink. | 2021 | Details |
A03615 | 33930586 | Clin Res Hepatol Gastroenterol | Pathogenetic mechanisms of nonalcoholic fatty liver disease and inhibition of the inflammasome as a new therapeutic target. | 2021 | Details |
A03618 | 33928675 | Hepatology | Inhibition of Secretin/Secretin Receptor Axis Ameliorates NAFLD Phenotypes. | 2021 | Details |
A03619 | 33928671 | Hepatology | Application of Artificial Intelligence for Diagnosis and Risk Stratification in NAFLD and NASH: The State of the Art. | 2021 | Details |
A03624 | 33926073 | Diagnostics (Basel) | Quantification of Liver Fibrosis, Steatosis, and Viscosity Using Multiparametric Ultrasound in Patients with Non-Alcoholic Liver Disease: A "Real-Life" Cohort Study. | 2021 | Details |
A03627 | 33925569 | Diagnostics (Basel) | Vibration-Controlled Transient Elastography and Controlled Attenuation Parameter for the Diagnosis of Liver Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03629 | 33924909 | Diagnostics (Basel) | Liver Fibrosis and Steatosis in Alström Syndrome: A Genetic Model for Metabolic Syndrome. | 2021 | Details |
A03631 | 33924165 | Int J Mol Sci | Flame Retardants-Mediated Interferon Signaling in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03633 | 33923817 | Int J Mol Sci | Role of Insulin Resistance in MAFLD. | 2021 | Details |
A03635 | 33923525 | Nutrients | The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights. | 2021 | Details |
A03637 | 33923295 | Int J Mol Sci | Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk. | 2021 | Details |
A03638 | 33923255 | Nutrients | Overview of Non-Alcoholic Fatty Liver Disease (NAFLD) and the Role of Sugary Food Consumption and Other Dietary Components in Its Development. | 2021 | Details |
A03642 | 33922256 | Molecules | Exploratory Study Using Urinary Volatile Organic Compounds for the Detection of Hepatocellular Carcinoma. | 2021 | Details |
A03650 | 33920670 | Int J Mol Sci | Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCC. | 2021 | Details |
A03654 | 33918467 | Biomedicines | Modeling Diet-Induced NAFLD and NASH in Rats: A Comprehensive Review. | 2021 | Details |
A03657 | 33917919 | Cancers (Basel) | The rs599839 A>G Variant Disentangles Cardiovascular Risk and Hepatocellular Carcinoma in NAFLD Patients. | 2021 | Details |
A03676 | 33908180 | J Hepatobiliary Pancreat Sci | Machine learning algorithm outperforms fibrosis markers in predicting significant fibrosis in biopsy-confirmed NAFLD. | 2021 | Details |
A03683 | 33903148 | Gut | Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target. | 2021 | Details |
A03687 | 33902187 | Zhonghua Gan Zang Bing Za Zhi | [Metabolic-associated fatty liver disease-related liver cirrhosis and cryptogenic liver cirrhosis]. | 2021 | Details |
A03692 | 33901295 | Hepatology | Functional Characterization of Organoids Derived From Irreversibly Damaged Liver of Patients With NASH. | 2021 | Details |
A03697 | 33899443 | Sheng Wu Yi Xue Gong Cheng Xue Za Zhi | [A review on cell-based models of human liver disease in vitro]. | 2021 | Details |
A03698 | 33899143 | Eur Radiol | Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis. | 2021 | Details |
A03701 | 33898959 | JHEP Rep | Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases. | 2021 | Details |
A03702 | 33898958 | JHEP Rep | Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. | 2021 | Details |
A03703 | 33897617 | Front Endocrinol (Lausanne) | Mining Gut Microbiota From Bariatric Surgery for MAFLD. | 2021 | Details |
A03704 | 33897616 | Front Endocrinol (Lausanne) | Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
A03707 | 33896117 | Liver Int | Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease. | 2021 | Details |
A03708 | 33896100 | Liver Int | Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects. | 2021 | Details |
A03710 | 33895552 | Biochem Biophys Res Commun | The PDE5 inhibitor udenafil ameliorates nonalcoholic fatty liver disease by improving mitochondrial function. | 2021 | Details |
A03712 | 33895182 | Metabolism | The progression and regression of metabolic dysfunction-associated fatty liver disease are associated with the development of subclinical atherosclerosis: A prospective analysis. | 2021 | Details |
A03714 | 33894425 | Cell Mol Gastroenterol Hepatol | Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis. | 2021 | Details |
A03716 | 33894145 | Lancet | Non-alcoholic fatty liver disease. | 2021 | Details |
A03717 | 33894100 | Liver Int | Diagnostic accuracy of fibrosis tests in children with non-alcoholic fatty liver disease: A systematic review. | 2021 | Details |
A03718 | 33894097 | Liver Int | A nonbile acid farnesoid X receptor agonist tropifexor potently inhibits cholestatic liver injury and fibrosis by modulating the gut-liver axis. | 2021 | Details |
A03723 | 33892010 | J Hepatol | Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease. | 2021 | Details |
A03725 | 33891332 | FASEB J | Silencing of STE20-type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet-induced nonalcoholic fatty liver disease. | 2021 | Details |
A03728 | 33889015 | Int J Gen Med | Correlation of Serum Transaminase Levels with Liver Fibrosis Assessed by Transient Elastography in Vietnamese Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03729 | 33887577 | Int Immunopharmacol | Neutrophil: An emerging player in the occurrence and progression of metabolic associated fatty liver disease. | 2021 | Details |
A03733 | 33885048 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | Effect of bariatric surgery on fatty liver disease in obese patients: A prospective one year follow-up study. | 2021 | Details |
A03736 | 33883616 | Sci Rep | Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients. | 2021 | Details |
A03738 | 33883285 | Endocr Connect | Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases. | 2021 | Details |
A03739 | 33883248 | Gut | Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease. | 2021 | Details |
A03744 | 33879971 | J Clin Biochem Nutr | Vitamin B6 efficacy in the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, single-center trial. | 2021 | Details |
A03746 | 33879861 | Exp Mol Med | The interplay of microRNAs and transcription factors in autophagy regulation in nonalcoholic fatty liver disease. | 2021 | Details |
A03748 | 33879084 | BMC Gastroenterol | Evaluating the prevalence and severity of NAFLD in primary care: the EPSONIP study protocol. | 2021 | Details |
A03750 | 33878875 | Arch Iran Med | Hepatic Steatosis and Fibrosis in Type 2 Diabetes: A Risk-Based Approach to Targeted Screening. | 2021 | Details |
A03751 | 33878156 | J Clin Endocrinol Metab | NAFLD and Liver Fibrosis Are Not Associated With Reduced Femoral Bone Mineral Density in the General US Population. | 2021 | Details |
A03752 | 33878116 | PLoS One | Leaf powder supplementation of Senna alexandrina ameliorates oxidative stress, inflammation, and hepatic steatosis in high-fat diet-fed obese rats. | 2021 | Details |
A03753 | 33877366 | Diabetologia | Liver-targeting drugs and their effect on blood glucose and hepatic lipids. | 2021 | Details |
A03757 | 33873073 | J Pharm Biomed Anal | Investigation of the therapeutic effect of Yinchen Wuling Powder on CCl4-induced hepatic fibrosis in rats by 1H NMR and MS-based metabolomics analysis. | 2021 | Details |
A03767 | 33871081 | J Gastroenterol Hepatol | Interplay between non-alcoholic fatty liver disease and cardiovascular risk in an asymptomatic general population. | 2021 | Details |
A03773 | 33868609 | Gastroenterol Hepatol Bed Bench | Efficacy of vitamin D supplementation on adult patients with non-alcoholic fatty liver disease: a single-center experience. | 2021 | Details |
A03775 | 33868162 | Front Endocrinol (Lausanne) | Association Between 10-Year Fracture Probability and Nonalcoholic Fatty Liver Disease With or Without Sarcopenia in Korean Men: A Nationwide Population-Based Cross-Sectional Study. | 2021 | Details |
A03776 | 33867442 | Eur J Gastroenterol Hepatol | Small intestinal bacterial overgrowth and orocecal transit time in patients of nonalcoholic fatty liver disease. | 2021 | Details |
A03778 | 33867326 | Pak J Pharm Sci | Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats. | 2020 | Details |
A03780 | 33866274 | J Stroke Cerebrovasc Dis | Liver Fibrosis is Associated with Ischemic Stroke Risk in Women but not Men: The REGARDS Study. | 2021 | Details |
A03788 | 33862553 | Int Immunopharmacol | Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis. | 2021 | Details |
A03791 | 33862225 | Clin Gastroenterol Hepatol | Maternal and Perinatal Risk Factors for Pediatric Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2021 | Details |
A03798 | 33861434 | Adv Exp Med Biol | The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. | 2021 | Details |
A03800 | 33860630 | FEBS J | Liver macrophages and inflammation in physiology and physiopathology of non-alcoholic fatty liver disease. | 2021 | Details |
A03802 | 33860214 | ACS Pharmacol Transl Sci | Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice. | 2021 | Details |
A03805 | 33860119 | Hepatol Commun | Serum Bile Acid, Vitamin E, and Serotonin Metabolites Are Associated With Future Liver-Related Events in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03806 | 33860118 | Hepatol Commun | Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD. | 2021 | Details |
A03808 | 33860116 | Hepatol Commun | Effects of Resmetirom on Noninvasive Endpoints in a 36-Week Phase 2 Active Treatment Extension Study in Patients With NASH. | 2021 | Details |
A03809 | 33860115 | Hepatol Commun | Type IV Collagen 7S Is the Most Accurate Test For Identifying Advanced Fibrosis in NAFLD With Type 2 Diabetes. | 2020 | Details |
A03810 | 33860113 | Hepatol Commun | Editorial: Noninvasive Fibrosis Biomarkers in Patients With NASH With Diabetes. | 2021 | Details |
A03812 | 33860040 | Biomed Res Int | The Relationship between Hepatic Myeloid-Derived Suppressor Cells and Clinicopathological Parameters in Patients with Chronic Liver Disease. | 2021 | Details |
A03814 | 33859484 | Diabetes Metab Syndr Obes | Significant Association Between Left Ventricular Diastolic Dysfunction, Left Atrial Performance and Liver Stiffness in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
A03815 | 33859314 | Sci Rep | Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr-/-.Leiden mice without attenuation of steatohepatitis. | 2021 | Details |
A03819 | 33857552 | Adv Drug Deliv Rev | Cellular protein markers, therapeutics, and drug delivery strategies in the treatment of diabetes-associated liver fibrosis. | 2021 | Details |
A03822 | 33856608 | Clin Exp Nephrol | Non-invasive fibrosis assessments of non-alcoholic fatty liver disease associated with low estimated glomerular filtration rate among CKD patients: the Fukuoka Kidney disease Registry Study. | 2021 | Details |
A03823 | 33856246 | Expert Opin Emerg Drugs | Emerging synthetic drugs for the treatment of liver cirrhosis. | 2021 | Details |
A03826 | 33856122 | ChemMedChem | Development and in vitro Profiling of Dual FXR/LTA4H Modulators. | 2021 | Details |
A03838 | 33852613 | PLoS One | Intrahepatic distribution of nerve fibers and alterations due to fibrosis in diseased liver. | 2021 | Details |
A03840 | 33852508 | Eur J Gastroenterol Hepatol | The role of nursing care in the type 2 diabetes treatment associated with chronic liver diseases. | 2022 | Details |
A03842 | 33851592 | Wiad Lek | THE ROLE OF ZONULIN IN THE DEVELOPMENT OF LIVER FIBROSIS IN OBESE ADOLESCENTS. | 2021 | Details |
A03844 | 33849437 | BMC Gastroenterol | Relationship between body composition and the histology of non-alcoholic fatty liver disease: a cross-sectional study. | 2021 | Details |
A03848 | 33848667 | Clin Res Hepatol Gastroenterol | Low serum alkaline phosphatase levels in patients with chronic liver diseases: Possible contributions to disease pathogenesis. | 2021 | Details |