Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06749 | 32760204 | Int J Biol Sci | Kupffer Cells in Non-alcoholic Fatty Liver Disease: Friend or Foe? | 2020 | Details |
| A06756 | 32758573 | Eur J Pharmacol | Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways. | 2020 | Details |
| A06762 | 32756704 | Food Funct | Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice. | 2020 | Details |
| A06773 | 32751983 | Biomolecules | Arachidonic Acid as an Early Indicator of Inflammation during Non-Alcoholic Fatty Liver Disease Development. | 2020 | Details |
| A06775 | 32751794 | Int J Mol Sci | Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice. | 2020 | Details |
| A06777 | 32751658 | Cells | The Inflammasome in Chronic Complications of Diabetes and Related Metabolic Disorders. | 2020 | Details |
| A06790 | 32745314 | Liver Int | LncRNA NEAT1: Shedding light on mechanisms and opportunities in liver diseases. | 2020 | Details |
| A06795 | 32742358 | Exp Ther Med | Pathophysiology of hepatic Na+/H+ exchange (Review). | 2020 | Details |
| A06802 | 32739658 | Nutrition | Chronic ingestion of Primex-Z, compared with other common fat sources, drives worse liver injury and enhanced susceptibility to bacterial infections. | 2020 | Details |
| A06809 | 32738301 | Biochim Biophys Acta Mol Cell Biol Lipids | Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells. | 2020 | Details |
| A06814 | 32737656 | Inflammation | Electroacupuncture Attenuates Liver Inflammation in Nonalcoholic Fatty Liver Disease Rats. | 2020 | Details |
| A06820 | 32734608 | J Pharm Pharmacol | HWL-088, a new and highly effective FFA1/PPARδ dual agonist, attenuates nonalcoholic steatohepatitis by regulating lipid metabolism, inflammation and fibrosis. | 2020 | Details |
| A06831 | 32731119 | Cytokine | Osteocalcin and osteoprotegerin levels and their relationship with adipokines and proinflammatory cytokines in children with nonalcoholic fatty liver disease. | 2020 | Details |
| A06837 | 32729704 | Minerva Med | Ancient wheats: beneficial effects on insulin resistance. | 2020 | Details |
| A06851 | 32724031 | Minerva Gastroenterol Dietol | Helicobacter pylori and non-alcoholic fatty liver disease. | 2020 | Details |
| A06862 | 32718371 | Br J Nutr | Lactobacillus casei YRL577 ameliorates markers of non-alcoholic fatty liver and alters expression of genes within the intestinal bile acid pathway. | 2020 | Details |
| A06866 | 32717871 | Int J Mol Sci | Gut Microbiota Metabolites in NAFLD Pathogenesis and Therapeutic Implications. | 2020 | Details |
| A06868 | 32717288 | J Hepatol | Targeting NFATc4 attenuates non-alcoholic steatohepatitis in mice. | 2020 | Details |
| A06873 | 32715385 | Arch Pharm Res | Ganoderic acid A attenuates high-fat-diet-induced liver injury in rats by regulating the lipid oxidation and liver inflammation. | 2020 | Details |
| A06877 | 32712601 | Aging (Albany NY) | Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. | 2020 | Details |
| A06880 | 32712045 | Asian J Surg | Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide +/ Sirtuin-1 pathway in mice. | 2020 | Details |
| A06882 | 32711187 | Transl Res | The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet. | 2020 | Details |
| A06884 | 32710880 | Arch Biochem Biophys | Eicosapentaenoic acid-containing polar lipids from seaweed Susabinori (Pyropia yezoensis) alleviate hepatic steatosis in obese db/db mice. | 2020 | Details |
| A06904 | 32702499 | Ann Hepatol | STAT3: A key regulator in liver fibrosis. | 2020 | Details |
| A06911 | 32700499 | Minerva Gastroenterol Dietol | Fibromax and inflamatory markers cannot replace liver biopsy in the evaluation of non-alcoholic fatty liver disease. | 2020 | Details |
| A06912 | 32699301 | Sci Rep | Hyperglycemia-stimulating diet induces liver steatosis in sheep. | 2020 | Details |
| A06913 | 32699233 | Sci Rep | MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice. | 2020 | Details |
| A06927 | 32695965 | JHEP Rep | Imaging and immunometabolic phenotyping uncover changes in the hepatic immune response in the early phases of NAFLD. | 2020 | Details |
| A06933 | 32694734 | Nat Metab | Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis. | 2020 | Details |
| A06938 | 32692879 | Mol Nutr Food Res | Inflammatory Diseases and Vitamin E-What Do We Know and Where Do We Go? | 2020 | Details |
| A06944 | 32690594 | J Lipid Res | Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease. | 2020 | Details |
| A06952 | 32688217 | J Nutr Biochem | Epigallocatechin gallate but not catechin prevents nonalcoholic steatohepatitis in mice similar to green tea extract while differentially affecting the gut microbiota. | 2020 | Details |
| A06960 | 32685988 | J Cancer Res Clin Oncol | Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas. | 2020 | Details |
| A06961 | 32685936 | Explor Med | Nonalcoholic fatty liver disease and portal hypertension. | 2020 | Details |
| A06975 | 32680977 | Aging (Albany NY) | Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway. | 2020 | Details |
| A06980 | 32677680 | Clin Sci (Lond) | Non-alcoholic fatty liver disease: a metabolic burden promoting atherosclerosis. | 2020 | Details |
| A06990 | 32670822 | J Tradit Complement Med | The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease. | 2020 | Details |
| A06993 | 32668632 | Int J Mol Sci | Common Drug Pipelines for the Treatment of Diabetic Nephropathy and Hepatopathy: Can We Kill Two Birds with One Stone? | 2020 | Details |
| A07000 | 32665525 | Gastroenterol Nurs | Ulcerative Colitis as an Independent Risk Factor for Hepatic Steatosis. | 2021 | Details |
| A07006 | 32663195 | J Clin Invest | Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes. | 2020 | Details |
| A07013 | 32657776 | J Clin Invest | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. | 2020 | Details |
| A07014 | 32657670 | J Am Coll Nutr | Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2020 | Details |
| A07016 | 32655764 | Oxid Med Cell Longev | Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation. | 2020 | Details |
| A07017 | 32655370 | Front Cell Neurosci | Dyslipidemic Diet Induces Mobilization of Peripheral Neutrophils and Monocytes That Exacerbate Hemorrhagic Brain Injury and Neuroinflammation. | 2020 | Details |
| A07028 | 32652799 | Liver Int | High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels. | 2020 | Details |
| A07037 | 32649507 | Chin Med J (Engl) | Intestinal epithelial chemokine (C-C motif) ligand 7 overexpression protects against high fat diet-induced obesity and hepatic steatosis in mice. | 2020 | Details |
| A07040 | 32647367 | Eur J Clin Nutr | The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial. | 2020 | Details |
| A07052 | 32640331 | Food Chem Toxicol | Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease. | 2020 | Details |
| A07055 | 32638913 | Rev Col Bras Cir | Comparison of the severity of non-alcoholic fatty liver disease in diabetic and non-diabetic obese patients. | 2020 | Details |
| A07091 | 32626829 | Hepatol Commun | Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis. | 2020 | Details |
| A07100 | 32622362 | J Neuroinflammation | Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. | 2020 | Details |
| A07107 | 32621046 | Cardiovasc Drugs Ther | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model. | 2021 | Details |
| A07110 | 32619269 | FEBS Lett | SHP-1 ameliorates nonalcoholic steatohepatitis by inhibiting proinflammatory cytokine production. | 2020 | Details |
| A07125 | 32613381 | Cell Biol Toxicol | Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists. | 2020 | Details |
| A07136 | 32606885 | Clin Exp Gastroenterol | Effects of Aerobic Exercise Protocol on Genes Related to Insulin Resistance and Inflammation in the Pancreas of ob/ob Mice with NAFLD. | 2020 | Details |
| A07138 | 32606597 | Drug Des Devel Ther | Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent. | 2020 | Details |
| A07150 | 32599319 | Int Immunopharmacol | Potential anti-inflammatory effect of dapagliflozin in HCHF diet- induced fatty liver degeneration through inhibition of TNF-α, IL-1β, and IL-18 in rat liver. | 2020 | Details |
| A07157 | 32597705 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial oxidative injury: a key player in nonalcoholic fatty liver disease. | 2020 | Details |
| A07165 | 32595023 | Obes Res Clin Pract | Pro-inflammatory HDL in women with obesity and nonalcoholic steatohepatitis. | 2020 | Details |
| A07166 | 32594969 | J Dev Orig Health Dis | Post-weaning exposure to high-sucrose diet induces early non-alcoholic fatty liver disease onset and progression in male mice: role of dysfunctional white adipose tissue. | 2020 | Details |
| A07175 | 32592657 | Cell Metab | In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19. | 2020 | Details |
| A07179 | 32592194 | Hepatology | iRhom2 Promotes Hepatic Steatosis by Activating MAP3K7-Dependent Pathway. | 2021 | Details |
| A07183 | 32591434 | Gut | Loss of hepatic Mboat7 leads to liver fibrosis. | 2020 | Details |
| A07188 | 32589264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | 2020 | Details |
| A07196 | 32586422 | Reprod Fertil Dev | Ovulation mitigates fatty liver associated with reproductive suppression and oxidative stress in Damaraland mole-rats (Fukomys damarensis). | 2020 | Details |
| A07198 | 32585734 | Scand J Med Sci Sports | The impact of high-intensity interval training on inflammatory markers in metabolic disorders: A meta-analysis. | 2020 | Details |
| A07210 | 32581811 | Front Pharmacol | Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07213 | 32579995 | Toxicol Lett | Long-term profile of serological biomarkers, hepatic inflammation, and fibrosis in a mouse model of non-alcoholic fatty liver disease. | 2020 | Details |
| A07214 | 32579753 | J Food Sci | Psoralea corylifolia L. extract ameliorates nonalcoholic fatty liver disease in free-fatty-acid-incubated HEPG2 cells and in high-fat diet-fed mice. | 2020 | Details |
| A07219 | 32577775 | Inflamm Res | Pathobiological and molecular connections involved in the high fructose and high fat diet induced diabetes associated nonalcoholic fatty liver disease. | 2020 | Details |
| A07223 | 32576050 | Gut Microbes | Sex-specific maternal calcium requirements for the prevention of nonalcoholic fatty liver disease by altering the intestinal microbiota and lipid metabolism in the high-fat-diet-fed offspring mice. | 2020 | Details |
| A07226 | 32574665 | Life Sci | Combination of luteolin and lycopene effectively protect against the "two-hit" in NAFLD through Sirt1/AMPK signal pathway. | 2020 | Details |
| A07227 | 32574624 | Gastroenterology | IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis. | 2020 | Details |
| A07242 | 32570937 | Nutrients | Treatment of Non-Alcoholic Steatosis: Preclinical Study of a New Nutraceutical Multitarget Formulation. | 2020 | Details |
| A07244 | 32569680 | Metabolism | Metabolic liver disease in diabetes - From mechanisms to clinical trials. | 2020 | Details |
| A07254 | 32566088 | Oxid Med Cell Longev | Cholesterol Induces Nrf-2- and HIF-1α-Dependent Hepatocyte Proliferation and Liver Regeneration to Ameliorate Bile Acid Toxicity in Mouse Models of NASH and Fibrosis. | 2020 | Details |
| A07261 | 32562600 | Immunity | Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis. | 2020 | Details |
| A07264 | 32561910 | Am J Clin Pathol | Steatohepatitis-Like Changes in Hepatocellular Adenoma. | 2020 | Details |
| A07269 | 32559586 | J Nutr Biochem | Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice. | 2020 | Details |
| A07273 | 32559006 | Liver Int | Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. | 2020 | Details |
| A07281 | 32556752 | Surg Endosc | Long-term effects of one-anastomosis gastric bypass on liver histopathology in NAFLD cases: a prospective study. | 2020 | Details |
| A07282 | 32556446 | Eur J Nutr | S-allylmercaptocysteine improves nonalcoholic steatohepatitis by enhancing AHR/NRF2-mediated drug metabolising enzymes and reducing NF-κB/IκBα and NLRP3/6-mediated inflammation. | 2020 | Details |
| A07287 | 32554245 | Biomed Pharmacother | 1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice. | 2020 | Details |
| A07311 | 32544504 | Eur J Pharmacol | Vitexin ameliorates chronic stress plub high fat diet-induced nonalcoholic fatty liver disease by inhibiting inflammation. | 2020 | Details |
| A07320 | 32540565 | Environ Pollut | Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis in CD-1 mice. | 2020 | Details |
| A07322 | 32538722 | Curr Protein Pept Sci | Gut Barrier Proteins Mediate Liver Regulation by the Effects of Serotonin on the Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07325 | 32536770 | World J Gastroenterol | Metabolic inflammation as an instigator of fibrosis during non-alcoholic fatty liver disease. | 2020 | Details |
| A07337 | 32531862 | Oral Dis | Bromelain reduces the non-alcoholic fatty liver disease and periodontal damages caused by ligature-induced periodontitis. | 2020 | Details |
| A07347 | 32529712 | Clin Physiol Funct Imaging | FDG PET/CT of the non-malignant liver in an increasingly obese world population. | 2020 | Details |
| A07348 | 32529694 | Mol Nutr Food Res | Resveratrol Alleviates Endoplasmic Reticulum Stress-Associated Hepatic Steatosis and Injury in Mice Challenged with Tunicamycin. | 2020 | Details |
| A07356 | 32526845 | Int J Mol Sci | N-Acetylcysteine Reduced Ischemia and Reperfusion Damage Associated with Steatohepatitis in Mice. | 2020 | Details |
| A07358 | 32526788 | Semin Liver Dis | The NLRP3 Inflammasome in Alcoholic and Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07359 | 32526787 | Semin Liver Dis | Nonalcoholic Steatohepatitis Promoting Kinases. | 2020 | Details |
| A07361 | 32526482 | Cell Mol Gastroenterol Hepatol | Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems. | 2020 | Details |
| A07362 | 32526241 | Eur J Pharmacol | Berbamine induced AMPK activation regulates mTOR/SREBP-1c axis and Nrf2/ARE pathway to allay lipid accumulation and oxidative stress in steatotic HepG2 cells. | 2020 | Details |
| A07367 | 32524150 | Naunyn Schmiedebergs Arch Pharmacol | Berberine attenuates non-alcoholic steatohepatitis by regulating chemerin/CMKLR1 signalling pathway and Treg/Th17 ratio. | 2020 | Details |
| A07375 | 32522273 | Trials | Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial. | 2020 | Details |
| A07378 | 32521450 | Biomed Pharmacother | Chinese herbal medicine mixture 919 syrup alleviates nonalcoholic fatty liver disease in rats by inhibiting the NF-κB pathway. | 2020 | Details |
| A07385 | 32518275 | Sci Rep | The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07387 | 32518225 | Nutr Diabetes | Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats. | 2020 | Details |