Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
Article ID | PMID | Source | Title | Publish Year | |
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A07013 | 32657776 | J Clin Invest | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. | 2020 | Details |
A07024 | 32654522 | Arch Physiol Biochem | The common variant of rs6214 in insulin like growth factor 1 (IGF1) gene: a potential protective factor for non-alcoholic fatty liver disease. | 2020 | Details |
A07037 | 32649507 | Chin Med J (Engl) | Intestinal epithelial chemokine (C-C motif) ligand 7 overexpression protects against high fat diet-induced obesity and hepatic steatosis in mice. | 2020 | Details |
A07040 | 32647367 | Eur J Clin Nutr | The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial. | 2020 | Details |
A07044 | 32645536 | Cytokine | Combination of asprosin and adiponectin as a novel marker for diagnosing non-alcoholic fatty liver disease. | 2020 | Details |
A07048 | 32643194 | Prenat Diagn | Perinatal exposure to maternal obesity: Lasting cardiometabolic impact on offspring. | 2020 | Details |
A07049 | 32642003 | Theranostics | Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance between cells/tissues. | 2020 | Details |
A07053 | 32640105 | J Intern Med | A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study. | 2020 | Details |
A07054 | 32639223 | Int J Vitam Nutr Res | Vitamin D levels are not associated with non-alcoholic fatty liver disease severity in a Brazilian population. | 2020 | Details |
A07057 | 32638541 | J Cachexia Sarcopenia Muscle | Association between muscle strength and advanced fibrosis in non-alcoholic fatty liver disease: a Korean nationwide survey. | 2020 | Details |
A07063 | 32636124 | Nutr Metab Cardiovasc Dis | Lower levels of plasma NT-proBNP are associated with higher prevalence of NASH in patients with biopsy-proven NAFLD. | 2020 | Details |
A07069 | 32633873 | J Intern Med | Nonalcoholic fatty liver disease is associated with a decreased myocardial mechano-energetic efficiency. | 2020 | Details |
A07072 | 32631678 | Rev Neurol (Paris) | Metabolic alterations in spinal and bulbar muscular atrophy. | 2020 | Details |
A07082 | 32629394 | EBioMedicine | MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD. | 2020 | Details |
A07086 | 32628351 | J Diabetes Investig | Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases. | 2020 | Details |
A07093 | 32626560 | Middle East J Dig Dis | Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events. | 2020 | Details |
A07094 | 32625166 | Front Endocrinol (Lausanne) | Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity. | 2020 | Details |
A07101 | 32622088 | Biochim Biophys Acta Mol Cell Biol Lipids | The "discovery" of lipid droplets: A brief history of organelles hidden in plain sight. | 2020 | Details |
A07107 | 32621046 | Cardiovasc Drugs Ther | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model. | 2021 | Details |
A07109 | 32620521 | Dig Liver Dis | Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration. | 2020 | Details |
A07111 | 32619031 | Diabet Med | Mechanisms, screening modalities and treatment options for individuals with non-alcoholic fatty liver disease and type 2 diabetes. | 2020 | Details |
A07112 | 32618656 | Am J Gastroenterol | Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial. | 2020 | Details |
A07124 | 32613718 | Diabetes Obes Metab | Vitamin D for treatment of non-alcoholic fatty liver disease detected by transient elastography: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
A07128 | 32610115 | J Hepatol | Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials. | 2020 | Details |
A07136 | 32606885 | Clin Exp Gastroenterol | Effects of Aerobic Exercise Protocol on Genes Related to Insulin Resistance and Inflammation in the Pancreas of ob/ob Mice with NAFLD. | 2020 | Details |
A07147 | 32603046 | Acta Gastroenterol Belg | A 3'-untranslated region variant (rs2289046) of insulin receptor substrate 2 gene is associated with susceptibility to nonalcoholic fatty liver disease. | 2020 | Details |
A07148 | 32602214 | Hepatol Res | Clinical and anthropometric characteristics of non-obese non-alcoholic fatty liver disease subjects in Japan. | 2020 | Details |
A07149 | 32599713 | Int J Mol Sci | Fructose and Uric Acid: Major Mediators of Cardiovascular Disease Risk Starting at Pediatric Age. | 2020 | Details |
A07152 | 32598715 | Ter Arkh | [Evaluation of the effectiveness of differentiated therapy of non-alcoholic fatty liver disease]. | 2020 | Details |
A07153 | 32598639 | Ter Arkh | [Diabetes mellitus and chronic liver diseases. Part 1: general mechanisms of etiology and pathogenesis]. | 2019 | Details |
A07157 | 32597705 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial oxidative injury: a key player in nonalcoholic fatty liver disease. | 2020 | Details |
A07161 | 32595752 | Evid Based Complement Alternat Med | Adlay Seed (Coix lacryma-jobi L.) Extracts Exhibit a Prophylactic Effect on Diet-Induced Metabolic Dysfunction and Nonalcoholic Fatty Liver Disease in Mice. | 2020 | Details |
A07166 | 32594969 | J Dev Orig Health Dis | Post-weaning exposure to high-sucrose diet induces early non-alcoholic fatty liver disease onset and progression in male mice: role of dysfunctional white adipose tissue. | 2020 | Details |
A07167 | 32594797 | Hypertension | Nonalcoholic Fatty Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories. | 2020 | Details |
A07171 | 32593710 | Life Sci | Bisphenol-A exposure worsens hepatic steatosis in ovariectomized mice fed on a high-fat diet: Role of endoplasmic reticulum stress and fibrogenic pathways. | 2020 | Details |
A07176 | 32592532 | Phytother Res | Sophoricoside is a selective LXRβ antagonist with potent therapeutic effects on hepatic steatosis of mice. | 2020 | Details |
A07179 | 32592194 | Hepatology | iRhom2 Promotes Hepatic Steatosis by Activating MAP3K7-Dependent Pathway. | 2021 | Details |
A07180 | 32591906 | Pflugers Arch | Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease. | 2020 | Details |
A07188 | 32589264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | 2020 | Details |
A07199 | 32585242 | Life Sci | IGFBP5 modulates lipid metabolism and insulin sensitivity through activating AMPK pathway in non-alcoholic fatty liver disease. | 2020 | Details |
A07203 | 32583961 | Clin Transl Sci | Evolving Role for Pharmacotherapy in NAFLD/NASH. | 2020 | Details |
A07208 | 32582754 | Front Nutr | PTEN: A Thrifty Gene That Causes Disease in Times of Plenty? | 2020 | Details |
A07212 | 32580141 | EBioMedicine | Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans. | 2020 | Details |
A07219 | 32577775 | Inflamm Res | Pathobiological and molecular connections involved in the high fructose and high fat diet induced diabetes associated nonalcoholic fatty liver disease. | 2020 | Details |
A07224 | 32576036 | Endocr Pract | ROLE OF ANDROGEN IN LIVER FAT CONTENT IN WOMEN: METABOLICALLY ADVANTAGEOUS OR DISADVANTAGEOUS? | 2020 | Details |
A07231 | 32573497 | JCI Insight | Leptin decreases de novo lipogenesis in patients with lipodystrophy. | 2020 | Details |
A07244 | 32569680 | Metabolism | Metabolic liver disease in diabetes - From mechanisms to clinical trials. | 2020 | Details |
A07250 | 32566571 | Ann Transl Med | Association between ratio of γ-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study. | 2020 | Details |
A07260 | 32562818 | Pharmacol Res | ZLY032, the first-in-class dual FFA1/PPARδ agonist, improves glucolipid metabolism and alleviates hepatic fibrosis. | 2020 | Details |
A07269 | 32559586 | J Nutr Biochem | Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice. | 2020 | Details |
A07273 | 32559006 | Liver Int | Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. | 2020 | Details |
A07283 | 32555989 | Arch Endocrinol Metab | Nonalcoholic fatty liver disease in women with polycystic ovary syndrome: associated factors and noninvasive fibrosis staging in a single Brazilian center. | 2020 | Details |
A07287 | 32554245 | Biomed Pharmacother | 1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice. | 2020 | Details |
A07296 | 32552211 | Expert Rev Gastroenterol Hepatol | Genetics and epigenetics purpose in nonalcoholic fatty liver disease. | 2020 | Details |
A07300 | 32550210 | J Diabetes Metab Disord | Mediterranean diet for patients with non-alcoholic fatty liver disease, a systematic review and meta-analysis of observational and clinical investigations. | 2020 | Details |
A07310 | 32545215 | Diagnostics (Basel) | Could SCGF-Beta Levels Be Associated with Inflammation Markers and Insulin Resistance in Male Patients Suffering from Obesity-Related NAFLD? | 2020 | Details |
A07318 | 32540813 | Ann Biol Clin (Paris) | [Mutltifaceted biological roles of adiponectin]. | 2020 | Details |
A07333 | 32533233 | Pathologe | [Histopathological diagnosis and differential diagnosis of nonalcoholic fatty liver disease]. | 2020 | Details |
A07335 | 32532003 | Int J Mol Sci | Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men. | 2020 | Details |
A07340 | 32531370 | Int J Biol Macromol | The protective effects of walnut green husk polysaccharide on liver injury, vascular endothelial dysfunction and disorder of gut microbiota in high fructose-induced mice. | 2020 | Details |
A07351 | 32528557 | Diabetol Metab Syndr | Association of [1H]-MRS quantified liver fat content with glucose metabolism status. | 2020 | Details |
A07375 | 32522273 | Trials | Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial. | 2020 | Details |
A07382 | 32519009 | Curr Diab Rep | Purine Metabolite Signatures and Type 2 Diabetes: Innocent Bystanders or Actionable Items? | 2020 | Details |
A07385 | 32518275 | Sci Rep | The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07394 | 32515880 | Liver Int | Mechanisms for increased risk of diabetes in chronic liver diseases. | 2020 | Details |
A07405 | 32514025 | Nutr Diabetes | Association between famine exposure in early life with insulin resistance and beta cell dysfunction in adulthood. | 2020 | Details |
A07407 | 32512752 | Nutrients | The Effect of Three Mediterranean Diets on Remnant Cholesterol and Non-Alcoholic Fatty Liver Disease: A Secondary Analysis. | 2020 | Details |
A07408 | 32512581 | PLoS One | Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet. | 2020 | Details |
A07410 | 32512072 | Toxicol Appl Pharmacol | Diosmin ameliorates inflammation, insulin resistance, and fibrosis in an experimental model of non-alcoholic steatohepatitis in rats. | 2020 | Details |
A07415 | 32508918 | Int J Endocrinol | Neck Circumference is an Effective Supplement for Nonalcoholic Fatty Liver Disease Screening in a Community-Based Population. | 2020 | Details |
A07421 | 32507439 | Complement Ther Med | Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial. | 2020 | Details |
A07424 | 32505776 | Clin Chim Acta | Intestinal microbiota-farnesoid X receptor axis in metabolic diseases. | 2020 | Details |
A07430 | 32502637 | Pharmacol Res | Molecular mechanisms of hepatic insulin resistance in nonalcoholic fatty liver disease and potential treatment strategies. | 2020 | Details |
A07432 | 32499918 | Gastroenterol Rep (Oxf) | Effect of Helicobacter pylori-eradication therapy on hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomized-controlled pilot study. | 2019 | Details |
A07441 | 32495731 | Proc Nutr Soc | Report of a member-led meeting: how stable isotope techniques can enhance human nutrition research. | 2020 | Details |
A07449 | 32491288 | Physiol Int | Betanin effect on PPAR-α and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis. | 2020 | Details |
A07454 | 32489856 | Integr Med Res | Herbal formulation MIT ameliorates high-fat diet-induced non-alcoholic fatty liver disease. | 2020 | Details |
A07457 | 32488147 | Sci Rep | Decrease in waist-to-hip ratio reduced the development of chronic kidney disease in non-obese non-alcoholic fatty liver disease. | 2020 | Details |
A07462 | 32485838 | Int J Mol Sci | The Role of Insulin Resistance and Diabetes in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07468 | 32483549 | Pediatr Gastroenterol Hepatol Nutr | A Nomogram for Predicting Non-Alcoholic Fatty Liver Disease in Obese Children. | 2020 | Details |
A07470 | 32483260 | Sci Rep | Endothelial dysfunction in nonalcoholic steatohepatitis with low cardiac disease risk. | 2020 | Details |
A07481 | 32477116 | Front Pharmacol | Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application. | 2020 | Details |
A07491 | 32475757 | Pancreatology | Liver and pancreas: 'Castor and Pollux' regarding the relationship between hepatic steatosis and pancreas exocrine insufficiency. | 2020 | Details |
A07500 | 32472367 | Curr Nutr Rep | Kefir in the Prevention and Treatment of Obesity and Metabolic Disorders. | 2020 | Details |
A07522 | 32460140 | Atherosclerosis | Hepatocyte-like cells derived from induced pluripotent stem cells: A versatile tool to understand lipid disorders. | 2020 | Details |
A07531 | 32454173 | J Ethnopharmacol | An unbiased lipidomics approach identifies key lipid molecules as potential therapeutic targets of Dohongsamul-tang against non-alcoholic fatty liver diseases in a mouse model of obesity. | 2020 | Details |
A07542 | 32450149 | Gastroenterology | Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122. | 2020 | Details |
A07564 | 32442908 | Cytokine | Gastric banding-associated weight loss diminishes hepatic Tsukushi expression. | 2020 | Details |
A07566 | 32440840 | J Nephrol | Therapeutic implications of shared mechanisms in non-alcoholic fatty liver disease and chronic kidney disease. | 2020 | Details |
A07570 | 32440483 | Adv Sci (Weinh) | Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder. | 2020 | Details |
A07575 | 32438959 | Biomed Environ Sci | Peripheral Artery Disease and Risk of Fibrosis Deterioration in Nonalcoholic Fatty Liver Disease: A Prospective Investigation. | 2020 | Details |
A07599 | 32429590 | Nutrients | Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance. | 2020 | Details |
A07601 | 32429274 | Nutrients | The Protective Effect of Cynara Cardunculus Extract in Diet-Induced NAFLD: Involvement of OCTN1 and OCTN2 Transporter Subfamily. | 2020 | Details |
A07602 | 32428560 | Biochim Biophys Acta Mol Basis Dis | Mitochondrial dysfunction in metabolic syndrome. | 2020 | Details |
A07626 | 32415687 | Lipids | Relationships between Very Low-Density Lipoproteins-Ceramides, -Diacylglycerols, and -Triacylglycerols in Insulin-Resistant Men. | 2020 | Details |
A07631 | 32414691 | J Pharmacol Sci | Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet. | 2020 | Details |
A07643 | 32410680 | Lipids Health Dis | Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio. | 2020 | Details |
A07646 | 32410310 | Liver Int | Objectively measured sedentary time, physical activity and liver enzyme elevations in US Hispanics/Latinos. | 2020 | Details |
A07651 | 32408667 | Int J Environ Res Public Health | The Bisphenol A Induced Oxidative Stress in Non-Alcoholic Fatty Liver Disease Male Patients: A Clinical Strategy to Antagonize the Progression of the Disease. | 2020 | Details |
A07664 | 32404278 | Biochim Biophys Acta Mol Cell Biol Lipids | Niacin increases diet-induced hepatic steatosis in B6129 mice. | 2020 | Details |