Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08267 | 32180556 | Mol Metab | Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes. | 2020 | Details |
| A08275 | 32171848 | Chem Biol Interact | Sphingolipids and the link between alcohol and cancer. | 2020 | Details |
| A08276 | 32171530 | Biochem Biophys Res Commun | Liraglutide ameliorates obesity-related nonalcoholic fatty liver disease by regulating Sestrin2-mediated Nrf2/HO-1 pathway. | 2020 | Details |
| A08283 | 32169759 | Biomed Pharmacother | Gegen Qinlian Decoction abates nonalcoholic steatohepatitis associated liver injuries via anti-oxidative stress and anti-inflammatory response involved inhibition of toll-like receptor 4 signaling pathways. | 2020 | Details |
| A08292 | 32166700 | J Endocrinol Invest | A preliminary study: proteomic analysis of exosomes derived from thyroid-stimulating hormone-stimulated HepG2 cells. | 2020 | Details |
| A08295 | 32165444 | Diabetes Care | Intrahepatic Fat and Postprandial Glycemia Increase After Consumption of a Diet Enriched in Saturated Fat Compared With Free Sugars. | 2020 | Details |
| A08297 | 32164541 | BMC Gastroenterol | Physical activity intervention for non-diabetic patients with non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2020 | Details |
| A08306 | 32158445 | Front Immunol | CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism. | 2020 | Details |
| A08308 | 32158249 | Clin Exp Gastroenterol | Effect of Ginger Powder Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2020 | Details |
| A08312 | 32156524 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |
| A08316 | 32155178 | PLoS One | Gender differences in diet-induced steatotic disease in Cyp2b-null mice. | 2020 | Details |
| A08328 | 32151552 | Surg Obes Relat Dis | Management of nonalcoholic fatty liver disease and the role of bariatric surgery: a brief review for surgeons. | 2020 | Details |
| A08336 | 32149275 | JHEP Rep | Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism. | 2019 | Details |
| A08340 | 32147742 | Acta Derm Venereol | Molecular Genetics of Keratinization Disorders - What's New About Ichthyosis. | 2020 | Details |
| A08345 | 32147076 | Complement Ther Med | Effect of green coffee extract supplementation on serum adiponectin concentration and lipid profile in patients with non-alcoholic fatty liver disease: A randomized, controlled trial. | 2019 | Details |
| A08351 | 32145387 | Prostaglandins Other Lipid Mediat | Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease. | 2020 | Details |
| A08352 | 32145332 | J Ethnopharmacol | Promising therapeutic use of Baccharis trimera (less.) DC. as a natural hepatoprotective agent against hepatic lesions that are caused by multiple risk factors. | 2020 | Details |
| A08353 | 32145306 | Life Sci | Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol. | 2020 | Details |
| A08364 | 32143184 | EBioMedicine | Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes. | 2020 | Details |
| A08365 | 32143076 | Chemosphere | Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq. | 2020 | Details |
| A08373 | 32139507 | J Biol Chem | The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease. | 2020 | Details |
| A08376 | 32138593 | Prion | The role of cellular prion protein in lipid metabolism in the liver. | 2020 | Details |
| A08393 | 32128893 | J Gastroenterol Hepatol | Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway. | 2020 | Details |
| A08397 | 32126212 | Toxicol Appl Pharmacol | Benzyl isothiocyanate ameliorates high-fat/cholesterol/cholic acid diet-induced nonalcoholic steatohepatitis through inhibiting cholesterol crystal-activated NLRP3 inflammasome in Kupffer cells. | 2020 | Details |
| A08402 | 32124651 | Expert Rev Gastroenterol Hepatol | The effects of epigenetic modification on the occurrence and progression of liver diseases and the involved mechanism. | 2020 | Details |
| A08413 | 32121602 | Nutrients | Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling. | 2020 | Details |
| A08417 | 32119738 | J Nutr | One-Carbon Metabolism in Fatty Liver Disease and Fibrosis: One-Carbon to Rule Them All. | 2020 | Details |
| A08423 | 32116684 | Front Pharmacol | Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux. | 2020 | Details |
| A08425 | 32116145 | RNA Biol | GR-mediated FTO transactivation induces lipid accumulation in hepatocytes via demethylation of m6A on lipogenic mRNAs. | 2020 | Details |
| A08429 | 32114355 | Biomed Pharmacother | Huang-Qi San improves glucose and lipid metabolism and exerts protective effects against hepatic steatosis in high fat diet-fed rats. | 2020 | Details |
| A08432 | 32113467 | Lipids Health Dis | Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications. | 2020 | Details |
| A08448 | 32106111 | JCI Insight | Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly. | 2020 | Details |
| A08459 | 32103741 | BMC Gastroenterol | Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A08465 | 32100496 | Zhongguo Zhen Jiu | [Electroacupuncture combined with lifestyle control on obese nonalcoholic fatty liver disease: a randomized controlled trial]. | 2020 | Details |
| A08469 | 32098589 | Thyroid | Thyroid Hormone Analogues: An Update. | 2020 | Details |
| A08474 | 32096565 | Hepatology | Cardiolipin Synthase 1 Ameliorates NASH Through Activating Transcription Factor 3 Transcriptional Inactivation. | 2020 | Details |
| A08475 | 32096475 | Eur Cytokine Netw | Effect of folate supplementation on immunological and autophagy markers in experimental nonalcoholic fatty liver disease. | 2019 | Details |
| A08489 | 32090345 | J Food Sci | Effects and molecular mechanisms of Ninghong black tea extract in nonalcoholic fatty liver disease of rats. | 2020 | Details |
| A08498 | 32086244 | J Lipid Res | Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice. | 2020 | Details |
| A08500 | 32084429 | Metabolism | mTORC1-dependent protein synthesis and autophagy uncouple in the regulation of Apolipoprotein A-I expression. | 2020 | Details |
| A08501 | 32084378 | Cell Metab | Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly. | 2020 | Details |
| A08509 | 32081971 | Sci Rep | CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis. | 2020 | Details |
| A08522 | 32075905 | J Biol Chem | Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice. | 2020 | Details |
| A08524 | 32075112 | Int J Mol Sci | Secondhand Smoke Induces Liver Steatosis through Deregulation of Genes Involved in Hepatic Lipid Metabolism. | 2020 | Details |
| A08554 | 32063360 | Biochem Biophys Res Commun | Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice. | 2020 | Details |
| A08567 | 32058943 | EBioMedicine | Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes. | 2020 | Details |
| A08570 | 32057899 | Life Sci | The regulation of TFEB in lipid homeostasis of non-alcoholic fatty liver disease: Molecular mechanism and promising therapeutic targets. | 2020 | Details |
| A08580 | 32053033 | Expert Opin Ther Targets | Emerging therapeutic targets for NASH: key innovations at the preclinical level. | 2020 | Details |
| A08583 | 32051143 | J Biol Chem | Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease. | 2020 | Details |
| A08606 | 32043636 | FASEB J | REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. | 2020 | Details |
| A08616 | 32040895 | Klin Lab Diagn | [The Diagnostic Importance of Circulating MicroRNA for Non-Alcoholic Fatty Liver Disease (review of literature).] | 2019 | Details |
| A08640 | 32035613 | Biochem Biophys Res Commun | MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1. | 2020 | Details |
| A08657 | 32030821 | J Gastroenterol Hepatol | Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice. | 2020 | Details |
| A08658 | 32029710 | Cell Death Dis | Hepatocyte caveolin-1 modulates metabolic gene profiles and functions in non-alcoholic fatty liver disease. | 2020 | Details |
| A08661 | 32029456 | Genes Dev | The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism. | 2020 | Details |
| A08665 | 32028458 | Med Sci Sports Exerc | Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD. | 2020 | Details |
| A08671 | 32027126 | J Chem Inf Model | Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation. | 2020 | Details |
| A08680 | 32024826 | Nat Commun | Liver governs adipose remodelling via extracellular vesicles in response to lipid overload. | 2020 | Details |
| A08689 | 32020874 | BMC Complement Med Ther | Zhenqing recipe attenuates non-alcoholic fatty liver disease by regulating the SIK1/CRTC2 signaling in experimental diabetic rats. | 2020 | Details |
| A08691 | 32020770 | Pediatr Obes | Effect of the patatin-like phospholipase domain containing 3 gene (PNPLA3) I148M polymorphism on the risk and severity of nonalcoholic fatty liver disease and metabolic syndromes: A meta-analysis of paediatric and adolescent individuals. | 2020 | Details |
| A08700 | 32018285 | Dtsch Med Wochenschr | [Secondary causes of fatty liver disease - an update on pathogenesis, diagnosis and treatment strategies]. | 2020 | Details |
| A08708 | 32016448 | Mol Med Rep | Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling. | 2020 | Details |
| A08727 | 32010250 | Exp Ther Med | Integrated microRNA and proteome analysis reveal a regulatory module in hepatic lipid metabolism disorders in mice with subclinical hypothyroidism. | 2019 | Details |
| A08732 | 32007822 | J Nutr Biochem | Effects of (-)-epicatechin on the time course of the expression of perilipins in a diet-induced model of nonalcoholic steatohepatitis. | 2019 | Details |
| A08748 | 32001554 | Gut | Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker. | 2020 | Details |
| A08751 | 32001301 | Biochim Biophys Acta Mol Basis Dis | Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver. | 2020 | Details |
| A08754 | 32000567 | Adipocyte | Transplantation of brown adipose tissue up-regulates miR-99a to ameliorate liver metabolic disorders in diabetic mice by targeting NOX4. | 2020 | Details |
| A08758 | 31998789 | Biomed Res Int | Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1. | 2020 | Details |
| A08760 | 31998283 | Front Immunol | Absence of the Caspases 1/11 Modulates Liver Global Lipid Profile and Gut Microbiota in High-Fat-Diet-Induced Obese Mice. | 2020 | Details |
| A08768 | 31992372 | Br J Nutr | Flaxseed oil in the context of a weight loss programme ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease: a randomised double-blind controlled trial. | 2020 | Details |
| A08772 | 31990961 | PLoS One | Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis. | 2020 | Details |
| A08791 | 31982488 | Pharmacol Res | Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo. | 2020 | Details |
| A08801 | 31980690 | Sci Rep | Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis. | 2020 | Details |
| A08836 | 31969883 | Front Immunol | Optimization of In vivo Imaging Provides a First Look at Mouse Model of Non-Alcoholic Fatty Liver Disease (NAFLD) Using Intravital Microscopy. | 2020 | Details |
| A08837 | 31969822 | Front Pharmacol | Microarray Expression Profiling and Raman Spectroscopy Reveal Anti-Fatty Liver Action of Berberine in a Diet-Induced Larval Zebrafish Model. | 2020 | Details |
| A08840 | 31969650 | Sci Rep | Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects. | 2020 | Details |
| A08859 | 31960406 | Ann Hum Genet | Inhibition of miR-499-5p expression improves nonalcoholic fatty liver disease. | 2020 | Details |
| A08860 | 31959914 | Cell Death Differ | Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. | 2020 | Details |
| A08865 | 31957809 | Biochem J | C-Jun/C7ORF41/NF-κB axis mediates hepatic inflammation and lipid accumulation in NAFLD. | 2020 | Details |
| A08866 | 31957704 | Eur Cytokine Netw | lncRNA NEAT1 regulates fibrosis and inflammatory response induced by nonalcoholic fatty liver by regulating miR-506/GLI3. | 2019 | Details |
| A08868 | 31956867 | Food Funct | High fat diet incorporated with meat proteins changes biomarkers of lipid metabolism, antioxidant activities, and the serum metabolomic profile in Glrx1-/- mice. | 2020 | Details |
| A08888 | 31952262 | Int J Mol Sci | Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia. | 2020 | Details |
| A08892 | 31950587 | J Dig Dis | Effects and therapeutic mechanism of Yinzhihuang on steatohepatitis in rats induced by a high-fat, high-cholesterol diet. | 2020 | Details |
| A08894 | 31949886 | Oxid Med Cell Longev | Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism. | 2019 | Details |
| A08901 | 31947953 | J Clin Med | Randomised Clinical Trial: Calorie Restriction Regimen with Tomato Juice Supplementation Ameliorates Oxidative Stress and Preserves a Proper Immune Surveillance Modulating Mitochondrial Bioenergetics of T-Lymphocytes in Obese Children Affected by Non-Alcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A08927 | 31935398 | Eur J Pharmacol | Natural alkaloid and polyphenol compounds targeting lipid metabolism: Treatment implications in metabolic diseases. | 2020 | Details |
| A08928 | 31935149 | Crit Rev Clin Lab Sci | Fructose and hepatic insulin resistance. | 2020 | Details |
| A08936 | 31930920 | J Med Chem | The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease. | 2020 | Details |
| A08940 | 31930271 | Food Funct | The preventive effect of phenolic-rich extracts from Chinese sumac fruits against nonalcoholic fatty liver disease in rats induced by a high-fat diet. | 2020 | Details |
| A08953 | 31926991 | Eur J Pharmacol | Caveolin-1 alleviates lipid accumulation in NAFLD associated with promoting autophagy by inhibiting the Akt/mTOR pathway. | 2020 | Details |
| A08954 | 31926984 | J Ethnopharmacol | Sweroside ameliorates NAFLD in high-fat diet induced obese mice through the regulation of lipid metabolism and inflammatory response. | 2020 | Details |
| A08955 | 31926452 | J Nutr Biochem | The nonalcoholic fatty liver disease-like phenotype and lowered serum VLDL are associated with decreased expression and DNA hypermethylation of hepatic ApoB in male offspring of ApoE deficient mothers fed a with Western diet. | 2019 | Details |
| A08964 | 31923423 | Clin Chim Acta | Triglyceride metabolism and angiopoietin-like proteins in lipoprotein lipase regulation. | 2020 | Details |
| A08980 | 31916388 | Mol Nutr Food Res | Differentiated Hepatic Response to Fructose Intake during Adolescence Reveals the Increased Susceptibility to Non-Alcoholic Fatty Liver Disease of Maternal High-Fat Diet Male Rat Offspring. | 2020 | Details |
| A08982 | 31915709 | J Diabetes Res | Management of Diabetes Mellitus in Patients with Chronic Liver Diseases. | 2019 | Details |
| A08984 | 31915606 | J Clin Transl Hepatol | Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A08988 | 31914377 | Cell Metab | Leveraging Human Genetics to Identify Potential New Treatments for Fatty Liver Disease. | 2020 | Details |
| A08998 | 31909773 | Food Funct | Baicalein reduces hepatic fat accumulation by activating AMPK in oleic acid-induced HepG2 cells and high-fat diet-induced non-insulin-resistant mice. | 2020 | Details |
| A09011 | 31905026 | Am J Physiol Gastrointest Liver Physiol | Addition of trans fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis. | 2020 | Details |
| A09012 | 31905025 | Am J Physiol Gastrointest Liver Physiol | Investigating fibrosis and inflammation in an ex vivo NASH murine model. | 2020 | Details |