Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A13271 | 30057681 | Oxid Med Cell Longev | Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT. | 2018 | Details |
| A13276 | 30055626 | Lipids Health Dis | Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system. | 2018 | Details |
| A13314 | 30036865 | Cell Physiol Biochem | Cangju Qinggan Jiangzhi Decoction Reduces the Development of NonAlcoholic Steatohepatitis and Activation of Kupffer Cells. | 2018 | Details |
| A13327 | 30029691 | Cardiovasc Diabetol | Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats. | 2018 | Details |
| A13334 | 30026731 | Front Endocrinol (Lausanne) | Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. | 2018 | Details |
| A13336 | 30026586 | Sci Rep | Substitution of linoleic acid with α-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis. | 2018 | Details |
| A13344 | 30023333 | Adv Pharm Bull | Effects of Pharmacologic Dose of Resveratrol Supplementation on Oxidative/Antioxidative Status Biomarkers in Nonalcoholic Fatty Liver Disease Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2018 | Details |
| A13346 | 30019598 | Antioxid Redox Signal | Does Nox2 Overactivate in Children with Nonalcoholic Fatty Liver Disease? | 2018 | Details |
| A13349 | 30019089 | Eur J Nutr | Association between dietary total antioxidant capacity and hepatocellular ballooning in nonalcoholic steatohepatitis: a cross-sectional study. | 2018 | Details |
| A13353 | 30017991 | Free Radic Biol Med | The role of iron in hepatic inflammation and hepatocellular carcinoma. | 2018 | Details |
| A13356 | 30016988 | Lipids Health Dis | Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress. | 2018 | Details |
| A13367 | 30014320 | Hormones (Athens) | Sarcopenic obesity. | 2018 | Details |
| A13374 | 30012333 | Gastroenterology | Mitochondrial Dysfunction and Signaling in Chronic Liver Diseases. | 2018 | Details |
| A13376 | 30011790 | Int J Mol Sci | New Aspects of Lipotoxicity in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13382 | 30009361 | Folia Morphol (Warsz) | The differential effects of high-fat and high- -fructose diets on the liver of male albino rat and the proposed underlying mechanisms. | 2018 | Details |
| A13387 | 30006154 | Biochim Biophys Acta Mol Basis Dis | GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice. | 2018 | Details |
| A13388 | 30006135 | Arch Biochem Biophys | Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway. | 2018 | Details |
| A13391 | 30002817 | F1000Res | Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts. | 2018 | Details |
| A13403 | 29993072 | Food Funct | Involvement of autophagy in the beneficial effects of resveratrol in hepatic steatosis treatment. A comparison with energy restriction. | 2018 | Details |
| A13410 | 29991976 | Oxid Med Cell Longev | Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13411 | 29991872 | World J Gastroenterol | Apoptosis and non-alcoholic fatty liver diseases. | 2018 | Details |
| A13416 | 29989845 | Metab Syndr Relat Disord | Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome. | 2018 | Details |
| A13420 | 29987933 | J Agric Food Chem | Pectin Alleviates High Fat (Lard) Diet-Induced Nonalcoholic Fatty Liver Disease in Mice: Possible Role of Short-Chain Fatty Acids and Gut Microbiota Regulated by Pectin. | 2018 | Details |
| A13440 | 29973631 | Sci Rep | Association of Lipoprotein-Associated Phospholipase A2 with the Prevalence of Nonalcoholic Fatty Liver Disease: A Result from the APAC Study. | 2018 | Details |
| A13443 | 29971527 | Diabetologia | Effects of dapagliflozin and n-3 carboxylic acids on non-alcoholic fatty liver disease in people with type 2 diabetes: a double-blind randomised placebo-controlled study. | 2018 | Details |
| A13463 | 29959534 | Med Mol Morphol | Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes. | 2018 | Details |
| A13479 | 29956204 | Adv Exp Med Biol | Pathogenesis of NASH: How Metabolic Complications of Overnutrition Favour Lipotoxicity and Pro-Inflammatory Fatty Liver Disease. | 2018 | Details |
| A13487 | 29953740 | Basic Clin Pharmacol Toxicol | Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A13497 | 29947894 | Arch Toxicol | Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126. | 2018 | Details |
| A13502 | 29946793 | Amino Acids | Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro. | 2018 | Details |
| A13515 | 29936596 | Cell Mol Life Sci | Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease. | 2018 | Details |
| A13516 | 29936297 | Toxicol Lett | Isoniazid-induced hepatotoxicity and neurotoxicity in rats investigated by 1H NMR based metabolomics approach. | 2018 | Details |
| A13524 | 29931231 | J Nutr | Daily Consumption of Synbiotic Yogurt Decreases Liver Steatosis in Patients with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial. | 2018 | Details |
| A13527 | 29930001 | Arterioscler Thromb Vasc Biol | STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia. | 2018 | Details |
| A13540 | 29924135 | Braz J Med Biol Res | Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease. | 2018 | Details |
| A13547 | 29920340 | Free Radic Biol Med | B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD). | 2018 | Details |
| A13551 | 29915639 | Gastroenterology Res | A Case of Concomitant Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis Treated With CPAP Therapy. | 2018 | Details |
| A13577 | 29898626 | Adipocyte | Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. | 2018 | Details |
| A13591 | 29890650 | Foods | Protection by the Total Flavonoids from Rosa laevigata Michx Fruit against Lipopolysaccharide-Induced Liver Injury in Mice via Modulation of FXR Signaling. | 2018 | Details |
| A13598 | 29887885 | Adv Pharmacol Sci | Supplementation with Alpha-Tocopherol and Ascorbic Acid to Nonalcoholic Fatty Liver Disease's Statin Therapy in Men. | 2018 | Details |
| A13601 | 29883724 | Chem Biol Interact | Alisol A 24-acetate ameliorates nonalcoholic steatohepatitis by inhibiting oxidative stress and stimulating autophagy through the AMPK/mTOR pathway. | 2018 | Details |
| A13627 | 29864915 | Biomed Pharmacother | Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. | 2018 | Details |
| A13628 | 29864682 | J Nutr Biochem | Non-alcoholic fatty liver disease severity and metabolic complications in obese children: impact of omega-3 fatty acids. | 2018 | Details |
| A13639 | 29859945 | Exp Mol Pathol | The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss. | 2018 | Details |
| A13653 | 29855033 | Histol Histopathol | Early effects of high-fat diet, extra-virgin olive oil and vitamin D in a sedentary rat model of non-alcoholic fatty liver disease. | 2018 | Details |
| A13656 | 29853957 | Evid Based Complement Alternat Med | Capybara Oil Improves Hepatic Mitochondrial Dysfunction, Steatosis, and Inflammation in a Murine Model of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13657 | 29853945 | Evid Based Complement Alternat Med | The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13658 | 29852394 | Biomed Pharmacother | Naringin attenuates liver damage in streptozotocin-induced diabetic rats. | 2018 | Details |
| A13663 | 29849912 | Oxid Med Cell Longev | The Essential Element Manganese, Oxidative Stress, and Metabolic Diseases: Links and Interactions. | 2018 | Details |
| A13665 | 29849583 | Gastroenterol Res Pract | Exenatide Delays the Progression of Nonalcoholic Fatty Liver Disease in C57BL/6 Mice, Which May Involve Inhibition of the NLRP3 Inflammasome through the Mitophagy Pathway. | 2018 | Details |
| A13677 | 29844588 | Nat Rev Gastroenterol Hepatol | Noninvasive biomarkers in NAFLD and NASH - current progress and future promise. | 2018 | Details |
| A13678 | 29844386 | Nat Commun | The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. | 2018 | Details |
| A13692 | 29803928 | Biomed Pharmacother | Protective effects of cichoric acid on H2O2-induced oxidative injury in hepatocytes and larval zebrafish models. | 2018 | Details |
| A13693 | 29803897 | Clin Chim Acta | Uric acid and cardiovascular disease. | 2018 | Details |
| A13705 | 29799837 | PLoS One | Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. | 2018 | Details |
| A13735 | 29785077 | World J Gastroenterol | Mediterranean diet and nonalcoholic fatty liver disease. | 2018 | Details |
| A13750 | 29775890 | Biomed Pharmacother | Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates non-alcoholic fatty liver disease via improving oxidative stress and mitochondrial dysfunction. | 2018 | Details |
| A13793 | 29752170 | J Pediatr | Treating Obstructive Sleep Apnea and Chronic Intermittent Hypoxia Improves the Severity of Nonalcoholic Fatty Liver Disease in Children. | 2018 | Details |
| A13800 | 29749323 | Turk J Gastroenterol | Effects of Delta-tocotrienol Supplementation on Liver Enzymes, Inflammation, Oxidative stress and Hepatic Steatosis in Patients with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13815 | 29743925 | Evid Based Complement Alternat Med | Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay. | 2018 | Details |
| A13828 | 29738693 | Biochemistry (Mosc) | Cytochrome P450 1A1 (CYP1A1) Catalyzes Lipid Peroxidation of Oleic Acid-Induced HepG2 Cells. | 2018 | Details |
| A13865 | 29719880 | Drug Res (Stuttg) | Ethanol Extract of Crataegus Oxyacantha L. Ameliorate Dietary Non-Alcoholic Fatty Liver Disease in Rat. | 2018 | Details |
| A13869 | 29718361 | Toxicol Sci | Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13878 | 29713129 | World J Gastroenterol | Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. | 2018 | Details |
| A13879 | 29713125 | World J Gastroenterol | Beneficial effects of naringenin in liver diseases: Molecular mechanisms. | 2018 | Details |
| A13886 | 29709653 | Life Sci | Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non-alcoholic steatohepatitis. | 2018 | Details |
| A13897 | 29704577 | Food Chem Toxicol | Food-drug interaction: Anabolic steroids aggravate hepatic lipotoxicity and nonalcoholic fatty liver disease induced by trans fatty acids. | 2018 | Details |
| A13901 | 29702089 | Chem Biol Interact | Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase. | 2018 | Details |
| A13913 | 29697385 | Georgian Med News | INTENSITY OF THE ANTIOXIDANT PROTECTION SYSTEM AND OXIDATIVE STRESS FACTORS IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS DEPENDING ON THE FORM OF CHRONIC KIDNEY DISEASE. | 2018 | Details |
| A13918 | 29693586 | Nutrients | Ellagic Acid Alleviates Hepatic Oxidative Stress and Insulin Resistance in Diabetic Female Rats. | 2018 | Details |
| A13930 | 29683981 | Eur J Gastroenterol Hepatol | Chronic liver diseases and the potential use of S-adenosyl-L-methionine as a hepatoprotector. | 2018 | Details |
| A13938 | 29679615 | Metabolism | Novel protective role of kallistatin in obesity by limiting adipose tissue low grade inflammation and oxidative stress. | 2018 | Details |
| A13949 | 29674209 | Steroids | Possible mechanisms underlying fatty liver in a rat model of male hypogonadism: A protective role for testosterone. | 2018 | Details |
| A13955 | 29672963 | Biofactors | Butein protects the nonalcoholic fatty liver through mitochondrial reactive oxygen species attenuation in rats. | 2018 | Details |
| A13963 | 29669855 | Sci Transl Med | Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. | 2018 | Details |
| A13980 | 29660503 | Redox Biol | High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. | 2018 | Details |
| A13987 | 29656250 | Environ Pollut | Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat. | 2018 | Details |
| A13988 | 29655752 | Food Chem | Systematic evaluation of phenolic compounds and protective capacity of a new mulberry cultivar J33 against palmitic acid-induced lipotoxicity using a simulated digestion method. | 2018 | Details |
| A13992 | 29654490 | Mol Neurobiol | Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. | 2018 | Details |
| A13994 | 29653359 | J Nutr Biochem | The role of the gut microbiota in the pathology and prevention of liver disease. | 2018 | Details |
| A13995 | 29653185 | Biochim Biophys Acta Mol Basis Dis | Sex differences in the development of hepatic steatosis in cafeteria diet-induced obesity in young mice. | 2018 | Details |
| A13997 | 29652567 | J Am Coll Nutr | A Khorasan Wheat-Based Replacement Diet Improves Risk Profile of Patients With Nonalcoholic Fatty Liver Disease (NAFLD): A Randomized Clinical Trial. | 2018 | Details |
| A14008 | 29637446 | J Physiol Biochem | Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. | 2018 | Details |
| A14020 | 29631603 | Lipids Health Dis | Heat shock protein 70 promotes lipogenesis in HepG2 cells. | 2018 | Details |
| A14038 | 29622764 | Exp Mol Med | Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease. | 2018 | Details |
| A14053 | 29608898 | Eur J Pharmacol | Canagliflozin protects against non-alcoholic steatohepatitis in type-2 diabetic rats through zinc alpha-2 glycoprotein up-regulation. | 2018 | Details |
| A14071 | 29602794 | Diabetes Care | Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A14081 | 29599925 | Oncotarget | A porcine placental extract prevents steatohepatitis by suppressing activation of macrophages and stellate cells in mice. | 2018 | Details |
| A14122 | 29574534 | J Gastroenterol | To die or not to die: death signaling in nonalcoholic fatty liver disease. | 2018 | Details |
| A14131 | 29571924 | J Hepatol | High red and processed meat consumption is associated with non-alcoholic fatty liver disease and insulin resistance. | 2018 | Details |
| A14140 | 29567249 | J Food Drug Anal | Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress. | 2017 | Details |
| A14172 | 29552625 | Cell Mol Gastroenterol Hepatol | Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2). | 2017 | Details |
| A14185 | 29545896 | Exp Ther Med | Influence of different concentrations of uric acid on oxidative stress in steatosis hepatocytes. | 2018 | Details |
| A14198 | 29531463 | World J Gastroenterol | Autophagy activation by Jiang Zhi Granule protects against metabolic stress-induced hepatocyte injury. | 2018 | Details |
| A14206 | 29526820 | Biochim Biophys Acta Mol Basis Dis | Benzbromarone aggravates hepatic steatosis in obese individuals. | 2018 | Details |
| A14210 | 29525610 | Nutr Res | Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways. | 2018 | Details |
| A14236 | 29511669 | Biomed Res Int | Ethanol Extract from Ulva prolifera Prevents High-Fat Diet-Induced Insulin Resistance, Oxidative Stress, and Inflammation Response in Mice. | 2018 | Details |
| A14241 | 29508520 | Mol Nutr Food Res | Sugary Kefir Strain Lactobacillus mali APS1 Ameliorated Hepatic Steatosis by Regulation of SIRT-1/Nrf-2 and Gut Microbiota in Rats. | 2018 | Details |
| A14253 | 29504312 | J Zhejiang Univ Sci B | Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders. | 2018 | Details |
| A14259 | 29499310 | Neurosci Lett | Spirulina maxima extract prevents cell death through BDNF activation against amyloid beta 1-42 (Aβ1-42) induced neurotoxicity in PC12 cells. | 2018 | Details |