Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Tumor necrosis factor1477 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A38378 | 11395389 | Am J Pathol | Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice. | 2001 | Details |
| A38417 | 11296694 | Semin Liver Dis | Etiopathogenesis of nonalcoholic steatohepatitis. | 2001 | Details |
| A39610 | 8270266 | Immunol Cell Biol | Recombinant cytokines as immunological adjuvants. | 1993 | Details |
| A42506 | 34342515 | Viral Immunol | TLR3\TLR7 as Differentially Expressed Markers Among Viral, Nonviral, and Autoimmune Diseases in Egyptian Patients. | 2021 | Details |
| A42749 | 33586126 | Am J Clin Dermatol | Psoriasis in Patients with Metabolic Syndrome or Type 2 Diabetes Mellitus: Treatment Challenges. | 2021 | Details |
| A42770 | 33525643 | Nutrients | The Marine Microalga, Tisochrysis lutea, Protects against Metabolic Disorders Associated with Metabolic Syndrome and Obesity. | 2021 | Details |
| A42837 | 33337585 | Ultrasound Q | Liver Stiffness Is Increased in Polycystic Ovary Syndrome and Related With Complement C1q/Tumor Necrosis Factor-Related Protein 3 Levels: A Point Shear Wave Elastography Study. | 2020 | Details |
| A42964 | 32939550 | J Nutr | A Novel Combination of Fruits and Vegetables Prevents Diet-Induced Hepatic Steatosis and Metabolic Dysfunction in Mice. | 2020 | Details |
| A43073 | 32626927 | Mol Med Rep | TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats. | 2020 | Details |
| A43230 | 32229664 | J Basic Clin Physiol Pharmacol | Altered composition of high-lipid diet may generate reactive oxygen species by disturbing the balance of antioxidant and free radicals. | 2020 | Details |
| A43607 | 31300671 | Sci Rep | Insulin resistance and metabonomics analysis of fatty liver haemorrhagic syndrome in laying hens induced by a high-energy low-protein diet. | 2019 | Details |
| A43769 | 30920040 | Aliment Pharmacol Ther | Editorial: biomarker predictors of non-response to TNFα antagonists - the quest continues. Authors' reply. | 2019 | Details |
| A43838 | 30741841 | J Clin Gastroenterol | Thirty Years of Lactobacillus rhamnosus GG: A Review. | 2019 | Details |
| A43908 | 30488325 | Ann Hematol | Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence? | 2018 | Details |
| A44001 | 30174510 | Saudi J Biol Sci | Effects of a medicinal plant Macrotyloma uniflorum (Lam.) Verdc.formulation (MUF) on obesity-associated oxidative stress-induced liver injury. | 2018 | Details |
| A44068 | 29973533 | Nutrients | Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes. | 2018 | Details |
| A44095 | 29768109 | J Am Coll Nutr | Effects of Phytosterol Supplementation on Serum Levels of Lipid Profiles, Liver Enzymes, Inflammatory Markers, Adiponectin, and Leptin in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. | 2018 | Details |
| A44228 | 29315298 | Nat Med | Lipid metabolic reprogramming in hepatic ischemia-reperfusion injury. | 2018 | Details |
| A44364 | 28834692 | J Mol Biol | Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-Induced Apoptosis by Disrupting Receptor-Receptor Interactions. | 2017 | Details |
| A44517 | 28386270 | PPAR Res | Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions. | 2017 | Details |
| A44558 | 28212760 | J Am Acad Dermatol | Psoriasis and comorbid diseases: Implications for management. | 2017 | Details |
| A44726 | 27534992 | J Lipid Res | Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis. | 2016 | Details |
| A44827 | 28868447 | GE Port J Gastroenterol | A Bugs Battle on Behalf of the Liver. | 2016 | Details |
| A44910 | 26858005 | Alcohol Clin Exp Res | Chronic Alcohol Consumption Causes Liver Injury in High-Fructose-Fed Male Mice Through Enhanced Hepatic Inflammatory Response. | 2016 | Details |
| A45537 | 24065684 | Genet Mol Res | Association between the TRAIL single nucleotide polymorphism rs1131580 and type 2 diabetes mellitus in a Han Chinese population. | 2013 | Details |
| A45575 | 23813872 | Hepatology | High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. | 2013 | Details |
| A45643 | 23486979 | J Nutr | Fatty liver accompanies an increase in lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet. | 2013 | Details |
| A45721 | 23099228 | Dig Liver Dis | Author reply: comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
| A45725 | 23058851 | Dig Liver Dis | Comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
| A45743 | 22991197 | Hepatology | Increased apoptosis induction in hepatocellular carcinoma by a novel tumor-targeted TRAIL fusion protein combined with bortezomib. | 2013 | Details |
| A45749 | 22964154 | Zhonghua Gan Zang Bing Za Zhi | [Simvastatin inhibits activation of hepatic stellate cells and promotes activation of adenosine monophosphate-activated protein kinase]. | 2012 | Details |
| A45758 | 22917635 | Dig Liver Dis | Comment on "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
| A45759 | 22909420 | Dig Liver Dis | Author reply: comment to "atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property". | 2012 | Details |
| A45831 | 22487461 | Dig Liver Dis | If steatosis is the atherosclerosis of the liver, are statins the "aspirin" for steatosis? | 2012 | Details |
| A45910 | 25755391 | J Clin Exp Hepatol | Hepatology elsewhere. | 2012 | Details |
| A45911 | 22125461 | ScientificWorldJournal | Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis. | 2011 | Details |
| A45930 | 21997755 | Dig Dis Sci | The effect of taurine on hepatic steatosis induced by thioacetamide in zebrafish (Danio rerio). | 2011 | Details |
| A46025 | 21505361 | J Pediatr Gastroenterol Nutr | Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease. | 2011 | Details |
| A46111 | 21038411 | Hepatology | Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins. | 2010 | Details |
| A46117 | 20967760 | Hepatology | Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease. | 2010 | Details |
| A46134 | 20822767 | Am J Obstet Gynecol | Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring. | 2010 | Details |
| A46141 | 20799351 | Hepatology | Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. | 2010 | Details |
| A46186 | 20470896 | Biochim Biophys Acta | Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis. | 2010 | Details |
| A46210 | 20370675 | Curr Pharm Des | Adiponectin: a key player in obesity related disorders. | 2010 | Details |
| A46234 | 20150556 | Arterioscler Thromb Vasc Biol | Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity. | 2010 | Details |
| A46249 | 20034047 | Hepatology | Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. | 2010 | Details |
| A46267 | 19918973 | Hepatology | Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice. | 2010 | Details |
| A46282 | 19788599 | J Gastroenterol Hepatol | Adiponectin in non-alcoholic steatohepatitis: an ideal culprit, but what are the proofs of its guilt? | 2009 | Details |
| A46289 | 19763702 | J Gastrointest Surg | Downregulation of adiponectin/AdipoR2 is associated with steatohepatitis in obese mice. | 2009 | Details |
| A46310 | 19585655 | Hepatology | Adipokines in liver diseases. | 2009 | Details |
| A46316 | 19561788 | Hippokratia | The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in non alcoholic fatty liver disease. | 2009 | Details |
| A46407 | 19027012 | Gastroenterology | Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. | 2008 | Details |
| A46418 | 20209757 | Rev Med Chir Soc Med Nat Iasi | [Adipocitokines and nonalcoholic steatohepatitis]. | 2010 | Details |
| A46423 | 18787467 | Eur J Gastroenterol Hepatol | Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis. | 2008 | Details |
| A46454 | 18523032 | J Endocrinol | Antagonism of central melanin-concentrating hormone 1 receptor alleviates steatohepatitis in mice. | 2008 | Details |
| A46488 | 18345311 | HPB (Oxford) | Nonalcoholic fatty pancreas disease. | 2007 | Details |
| A46500 | 18235842 | Mol Med | Inflammatory mechanisms in the regulation of insulin resistance. | 2008 | Details |
| A46517 | 18054848 | Dig Liver Dis | Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease. | 2007 | Details |
| A46555 | 17661402 | Hepatology | A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. | 2007 | Details |
| A46556 | 17656035 | Med Hypotheses | Adiponectin: is it a novel treatment modality to alleviate liver injury in non-alcoholic fatty liver disease (NAFLD)? | 2007 | Details |
| A46561 | 17578885 | Am J Physiol Endocrinol Metab | Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity. | 2007 | Details |
| A46590 | 17410454 | Dig Dis Sci | The effect of a silybin-vitamin e-phospholipid complex on nonalcoholic fatty liver disease: a pilot study. | 2007 | Details |
| A46643 | 16941682 | Hepatology | Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice. | 2006 | Details |
| A46644 | 16938178 | Zhonghua Gan Zang Bing Za Zhi | [Association between tumor necrosis factor-alpha gene polymorphism and insulin resistance in nonalcoholic fatty liver disease]. | 2006 | Details |
| A46682 | 16557554 | Hepatology | COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator. | 2006 | Details |
| A46721 | 16226915 | Hepatol Res | Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome. | 2005 | Details |
| A46725 | 16175608 | Hepatology | Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. | 2005 | Details |
| A46726 | 16175602 | Hepatology | Steatohepatitis induced by intragastric overfeeding in mice. | 2005 | Details |
| A46742 | 15990591 | Curr Opin Lipidol | Nonalcoholic fatty liver disease and the metabolic syndrome. | 2005 | Details |
| A46747 | 15976528 | Alcohol Clin Exp Res | Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. | 2005 | Details |
| A46755 | 15882516 | Med Clin (Barc) | [Pathogenesis of primary nonalcoholic fatty liver disease]. | 2005 | Details |
| A46773 | 15703606 | Curr Opin Gastroenterol | Innate immunity in the liver. | 2003 | Details |
| A46776 | 15670659 | Alcohol | Role of fatty liver, dietary fatty acid supplements, and obesity in the progression of alcoholic liver disease: introduction and summary of the symposium. | 2004 | Details |
| A46796 | 15349802 | Semin Liver Dis | Diagnosis and therapy of alcoholic liver disease. | 2004 | Details |
| A46818 | 14720455 | Curr Gastroenterol Rep | New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. | 2004 | Details |
| A46830 | 14499793 | Am J Gastroenterol | Current biochemical studies of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis suggest a new therapeutic approach. | 2003 | Details |
| A46879 | 11832442 | Gastroenterology | Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. | 2002 | Details |
| A46884 | 11447019 | Am J Physiol Gastrointest Liver Physiol | Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation. | 2001 | Details |
| A46885 | 11391044 | Alcohol Clin Exp Res | Nonalcoholic fatty liver disease: implications for alcoholic liver disease pathogenesis. | 2001 | Details |
| A46894 | 11078773 | N Engl J Med | Cytokines in alcoholic and nonalcoholic steatohepatitis. | 2000 | Details |
| A46964 | 32129352 | Food Funct | Rosmarinic acid alleviates ethanol-induced lipid accumulation by repressing fatty acid biosynthesis. | 2020 | Details |
| A47009 | 30179264 | Hepatology | Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. | 2019 | Details |
| A47031 | 28882574 | Toxicology | Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues. | 2017 | Details |
| A47059 | 27455313 | Nutrients | Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. | 2016 | Details |
| A47072 | 26858343 | Gut | Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors. | 2016 | Details |
| A47075 | 26801973 | BMC Complement Altern Med | Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease. | 2016 | Details |
| A47112 | 25789959 | Medicine (Baltimore) | Changes in tumor necrosis factor-α, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study. | 2015 | Details |
| A47115 | 25703252 | Alcohol Clin Exp Res | The adiponectin-SIRT1-AMPK pathway in alcoholic fatty liver disease in the rat. | 2015 | Details |
| A47122 | 25561792 | World J Gastroenterol | Delayed ethanol elimination and enhanced susceptibility to ethanol-induced hepatosteatosis after liver resection. | 2014 | Details |
| A47126 | 25494594 | Lipids Health Dis | Protective effect of corn peptides against alcoholic liver injury in men with chronic alcohol consumption: a randomized double-blind placebo-controlled study. | 2014 | Details |
| A47148 | 24835349 | Kaohsiung J Med Sci | Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients. | 2014 | Details |
| A47161 | 24656653 | Gastroenterol Hepatol | Alcoholic hepatitis: Prognosis and treatment. | 2014 | Details |
| A47173 | 24214181 | Hepatology | Osteopontin binding to lipopolysaccharide lowers tumor necrosis factor-α and prevents early alcohol-induced liver injury in mice. | 2014 | Details |
| A47177 | 24146112 | Arch Toxicol | Protective effects of dioscin against alcohol-induced liver injury. | 2013 | Details |
| A47182 | 23969550 | Alcohol Alcohol | Sex-specific differences in the development of acute alcohol-induced liver steatosis in mice. | 2013 | Details |
| A47197 | 23277536 | J Pharmacol Exp Ther | Puerarin ameliorates experimental alcoholic liver injury by inhibition of endotoxin gut leakage, Kupffer cell activation, and endotoxin receptors expression. | 2012 | Details |
| A47202 | 23023014 | J Hepatol | Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. | 2012 | Details |
| A47207 | 22902304 | Gene | Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population. | 2012 | Details |
| A47211 | 22745073 | Am J Chin Med | Protective effects of total flavonoids from Litsea coreana on alcoholic fatty liver in rats associated with down-regulation adipose differentiation-related protein expression. | 2012 | Details |
| A47213 | 22676331 | Alcohol Clin Exp Res | Thromboxane inhibitors attenuate inflammatory and fibrotic changes in rat liver despite continued ethanol administrations. | 2012 | Details |