Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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PPAR2265 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A22862 | 24269473 | J Hepatol | Perilipin discerns chronic from acute hepatocellular steatosis. | 2013 | Details |
| A22868 | 24265809 | PLoS One | Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family. | 2013 | Details |
| A22899 | 24224789 | Acta Physiol (Oxf) | Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring. | 2014 | Details |
| A22911 | 24219909 | Cell Signal | Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways. | 2013 | Details |
| A22921 | 24209497 | Lipids Health Dis | Nonalcoholic fatty liver disease: molecular pathways and therapeutic strategies. | 2013 | Details |
| A22933 | 24196354 | Int J Mol Sci | Hepatic adverse effects of fructose consumption independent of overweight/obesity. | 2013 | Details |
| A22979 | 24142602 | Eur Rev Med Pharmacol Sci | Curcumin decreases oleic acid-induced lipid accumulation via AMPK phosphorylation in hepatocarcinoma cells. | 2013 | Details |
| A22981 | 24140006 | Prostaglandins Leukot Essent Fatty Acids | A diet high in α-linolenic acid and monounsaturated fatty acids attenuates hepatic steatosis and alters hepatic phospholipid fatty acid profile in diet-induced obese rats. | 2013 | Details |
| A22996 | 24129399 | Am J Physiol Endocrinol Metab | Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. | 2013 | Details |
| A23009 | 24118921 | Hepatol Res | Hepatic molecular effects of rosiglitazone in human non-alcoholic steatohepatitis suggest long-term pro-inflammatory damage. | 2013 | Details |
| A23026 | 24100261 | Am J Gastroenterol | Cohort study of non-alcoholic fatty liver disease, NAFLD fibrosis score, and the risk of incident diabetes in a Korean population. | 2013 | Details |
| A23033 | 24091358 | Radiology | Nonalcoholic fatty liver disease: intravoxel incoherent motion diffusion-weighted MR imaging-an experimental study in a rabbit model. | 2013 | Details |
| A23059 | 24073298 | World J Hepatol | Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease. | 2013 | Details |
| A23076 | 24064383 | Free Radic Biol Med | CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. | 2013 | Details |
| A23082 | 24056123 | Eur J Pharmacol | Dysregulations of UDP-glucuronosyltransferases in rats with valproic acid and high fat diet induced fatty liver. | 2013 | Details |
| A23092 | 24047280 | Clin Exp Hypertens | The association between serum ferritin level, microalbuminuria and non-alcoholic fatty liver disease in non-diabetic, non-hypertensive men. | 2013 | Details |
| A23106 | 24038081 | Hepatology | All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade. | 2014 | Details |
| A23136 | 24010297 | Zhongguo Zhong Yao Za Zhi | [Investigation of a compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rhum palmatum, on metabolic syndrome treatment. IV--Improving liver lipid accumulation]. | 2013 | Details |
| A23150 | 24002947 | Hepatology | Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia. | 2014 | Details |
| A23151 | 24002776 | Hepatology | Extrahepatic complications of nonalcoholic fatty liver disease. | 2014 | Details |
| A23156 | 23998390 | Liver Int | Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes. | 2013 | Details |
| A23160 | 23996808 | Hepatology | Relationship between sarcopenia and nonalcoholic fatty liver disease: the Korean Sarcopenic Obesity Study. | 2014 | Details |
| A23162 | 23994650 | Transl Res | The serum level of soluble CD26/dipeptidyl peptidase 4 increases in response to acute hyperglycemia after an oral glucose load in healthy subjects: association with high-molecular weight adiponectin and hepatic enzymes. | 2013 | Details |
| A23163 | 23994574 | Free Radic Biol Med | Free radical biology for medicine: learning from nonalcoholic fatty liver disease. | 2013 | Details |
| A23164 | 25755505 | J Clin Exp Hepatol | MicroRNAs in Liver Disease: Bench to Bedside. | 2013 | Details |
| A23214 | 23954219 | Gene | Association between resistin +299A/A genotype and nonalcoholic fatty liver disease in Chinese patients with type 2 diabetes mellitus. | 2013 | Details |
| A23217 | 23951220 | PLoS One | Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus. | 2013 | Details |
| A23249 | 23928105 | Metabolism | Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. | 2013 | Details |
| A23256 | 23922565 | Hepat Mon | Association of Adiponectin rs1501299 and rs266729 Gene Polymorphisms With Nonalcoholic Fatty Liver Disease. | 2013 | Details |
| A23281 | 23900008 | Food Chem Toxicol | The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat diet-induced non-alcoholic fatty liver disease. | 2013 | Details |
| A23289 | 23896376 | Biochimie | Ectopic lipid accumulation: A potential cause for metabolic disturbances and a contributor to the alteration of kidney function. | 2013 | Details |
| A23294 | 23891824 | Gene | Peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms in nonalcoholic fatty liver disease: a study in Brazilian patients. | 2013 | Details |
| A23295 | 23891820 | Gene | Association between the Pro12Ala polymorphism of PPAR-γ gene and the non-alcoholic fatty liver disease: a meta-analysis. | 2013 | Details |
| A23298 | 23886860 | Am J Physiol Gastrointest Liver Physiol | Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment. | 2013 | Details |
| A23335 | 23861927 | PLoS One | Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. | 2013 | Details |
| A23369 | 23837138 | Clin Mol Hepatol | The influence of waist circumference on insulin resistance and nonalcoholic fatty liver disease in apparently healthy Korean adults. | 2013 | Details |
| A23381 | 23831119 | J Hepatol | Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells. | 2013 | Details |
| A23394 | 23819696 | Clin Exp Pharmacol Physiol | Supplementation of the maternal diet during pregnancy with chocolate and fructose interacts with the high-fat diet of the young to facilitate the onset of metabolic disorders in rat offspring. | 2013 | Details |
| A23418 | 23800945 | J Gastroenterol | Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23431 | 23791610 | Eur J Pharmacol | Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα). | 2013 | Details |
| A23463 | 23758436 | Clin Sci (Lond) | Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice. | 2013 | Details |
| A23466 | 23755269 | PLoS One | Lepr(db/db) Mice with senescence marker protein-30 knockout (Lepr(db/db)Smp30(Y/-)) exhibit increases in small dense-LDL and severe fatty liver despite being fed a standard diet. | 2013 | Details |
| A23467 | 23754536 | Mol Med Rep | Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation. | 2013 | Details |
| A23522 | 23711137 | Am J Chin Med | Triterpenoid-rich fraction from Ilex hainanensis Merr. attenuates non-alcoholic fatty liver disease induced by high fat diet in rats. | 2013 | Details |
| A23532 | 23703580 | Hepatology | Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2013 | Details |
| A23579 | 23660937 | Eur J Gastroenterol Hepatol | Noninvasive detection of hepatic steatosis in patients without ultrasonographic evidence of fatty liver using the controlled attenuation parameter evaluated with transient elastography. | 2013 | Details |
| A23584 | 23656726 | Br J Nutr | Effects of long-term administration of saturated and n-3 fatty acid-rich diets on lipid utilisation and oxidative stress in rat liver and muscle tissues. | 2013 | Details |
| A23588 | 23653642 | Int J Endocrinol | Nonalcoholic Fatty liver disease, diabetes mellitus and cardiovascular disease: newer data. | 2013 | Details |
| A23596 | 23647015 | Br J Pharmacol | Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. | 2013 | Details |
| A23606 | 23633195 | J Clin Endocrinol Metab | Association of glypican-4 with body fat distribution, insulin resistance, and nonalcoholic fatty liver disease. | 2013 | Details |
| A23616 | 23625197 | Curr Diab Rep | The future of thiazolidinedione therapy in the management of type 2 diabetes mellitus. | 2013 | Details |
| A23627 | 23618531 | J Nutr Biochem | Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice. | 2013 | Details |
| A23637 | 23607320 | Hepatol Res | Liver damage is not reversed during the lean period in diet-induced weight cycling in mice. | 2013 | Details |
| A23639 | 23605066 | Pflugers Arch | Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. | 2013 | Details |
| A23641 | 23603006 | Food Chem Toxicol | Amelioration by chicory seed extract of diabetes- and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARα and SREBP-1. | 2013 | Details |
| A23675 | 23576797 | Exp Biol Med (Maywood) | Medium chain triglycerides dose-dependently prevent liver pathology in a rat model of non-alcoholic fatty liver disease. | 2013 | Details |
| A23726 | 23531105 | Lipids Health Dis | Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospective. | 2013 | Details |
| A23732 | 23525389 | J Ultrasound Med | Targeted hepatic sonography during clinic visits for detection of fatty liver in overweight children: a pilot study. | 2013 | Details |
| A23799 | 23472083 | PLoS One | Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism. | 2013 | Details |
| A23812 | 23453039 | Metabolism | Involvement of regucalcin in lipid metabolism and diabetes. | 2013 | Details |
| A23819 | 23448101 | DNA Cell Biol | Does PPARγ2 gene Pro12Ala polymorphism affect nonalcoholic fatty liver disease risk? Evidence from a meta-analysis. | 2013 | Details |
| A23840 | 23433458 | Adv Pharmacol | Eicosanoids in metabolic syndrome. | 2013 | Details |
| A23848 | 23431284 | PPAR Res | Peroxisome proliferator-activated receptor genetic polymorphisms and nonalcoholic Fatty liver disease: any role in disease susceptibility? | 2013 | Details |
| A23874 | 23411507 | Endocr J | High serum vitamin D levels reduce the risk for nonalcoholic fatty liver disease in healthy men independent of metabolic syndrome. | 2013 | Details |
| A23888 | 23401753 | J Obes | Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice. | 2013 | Details |
| A23915 | 23390894 | Atherosclerosis | The clinical availability of non alcoholic fatty liver disease as an early predictor of the metabolic syndrome in Korean men: 5-year's prospective cohort study. | 2013 | Details |
| A23920 | 23389749 | Food Funct | Hibiscus sabdariffa L. aqueous extract attenuates hepatic steatosis through down-regulation of PPAR-γ and SREBP-1c in diet-induced obese mice. | 2013 | Details |
| A23954 | 23353867 | J Hepatol | Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis. | 2013 | Details |
| A23996 | 23318274 | Biochim Biophys Acta | The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease. | 2013 | Details |
| A24068 | 23269818 | Am J Clin Nutr | A common variant in the peroxisome proliferator-activated receptor-γ coactivator-1α gene is associated with nonalcoholic fatty liver disease in obese children. | 2012 | Details |
| A24070 | 23268566 | Scand J Gastroenterol | The role of Kupffer cells in the morphogenesis of nonalcoholic steatohepatitis - ultrastructural findings. The first report in pediatric patients. | 2012 | Details |
| A24092 | 23236228 | World J Gastroenterol | Genetic and epigenetic variants influencing the development of nonalcoholic fatty liver disease. | 2012 | Details |
| A24105 | 23226761 | Exp Ther Med | Tesaglitazar ameliorates non-alcoholic fatty liver disease and atherosclerosis development in diabetic low-density lipoprotein receptor-deficient mice. | 2012 | Details |
| A24121 | 23211853 | Am J Gastroenterol | Non-alcoholic fatty liver disease and obesity: not all about body mass index. | 2012 | Details |
| A24122 | 23211317 | J Hepatol | Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24127 | 23203768 | Mol Nutr Food Res | Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways. | 2012 | Details |
| A24147 | 23178979 | J Hepatol | Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. | 2012 | Details |
| A24154 | 23174781 | Hepatology | Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway. | 2013 | Details |
| A24155 | 23174676 | Acta Biochim Biophys Sin (Shanghai) | Antioxidant effect of apolipoprotein A-I on high-fat diet-induced non-alcoholic fatty liver disease in rabbits. | 2012 | Details |
| A24162 | 23165534 | Nutr Hosp | Possible molecular mechanisms soy-mediated in preventing and treating nonalcoholic fatty liver disease. | 2013 | Details |
| A24176 | 23146095 | Liver Int | Combined paediatric NAFLD fibrosis index and transient elastography to predict clinically significant fibrosis in children with fatty liver disease. | 2012 | Details |
| A24189 | 23139599 | World J Gastroenterol | Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease. | 2012 | Details |
| A24194 | 23134073 | Clin Endocrinol (Oxf) | Fibroblast growth factor 21 as an emerging metabolic regulator: clinical perspectives. | 2013 | Details |
| A24217 | 23112047 | J Biol Chem | Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model. | 2012 | Details |
| A24267 | 23063693 | Biochimie | A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα. | 2012 | Details |
| A24295 | 23031808 | Gene | Association of peroxisome proliferator activated receptor-γ gene with non-alcoholic fatty liver disease in Asian Indians residing in north India. | 2012 | Details |
| A24302 | 23024085 | Indian Pediatr | Non-alcoholic fatty liver disease in children. | 2012 | Details |
| A24344 | 22982377 | FASEB J | A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. | 2012 | Details |
| A24356 | 22973438 | PLoS One | Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha network. | 2012 | Details |
| A24363 | 22966224 | PPAR Res | Update on pparγ and nonalcoholic Fatty liver disease. | 2012 | Details |
| A24398 | 22935341 | Nutr Res | The lipid accumulation product is highly related to serum alanine aminotransferase level in male adults. | 2012 | Details |
| A24431 | 22902548 | J Hepatol | Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. | 2012 | Details |
| A24435 | 22899406 | Georgian Med News | [Peculiarities of metabolic syndrome and nonalcogolic fatty liver disease in menopausal women]. | 2012 | Details |
| A24458 | 22876038 | World J Gastroenterol | Moro orange juice prevents fatty liver in mice. | 2012 | Details |
| A24462 | 22872676 | FASEB J | Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism. | 2012 | Details |
| A24464 | 22871499 | J Hepatol | Prevalence and risk factors of non-alcoholic fatty liver disease in the elderly: results from the Rotterdam study. | 2012 | Details |
| A24468 | 22864747 | Arch Pharm Res | Protective effects of gypenosides against fatty liver disease induced by high fat and cholesterol diet and alcohol in rats. | 2012 | Details |
| A24502 | 22827449 | Clin Sci (Lond) | Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model. | 2013 | Details |
| A24517 | 22820754 | Tohoku J Exp Med | The C-681G polymorphism of the PPAR-γ gene is associated with susceptibility to non-alcoholic fatty liver disease. | 2012 | Details |
| A24561 | 22749137 | J Nutr Biochem | Lactobacillus casei Shirota protects from fructose-induced liver steatosis: a mouse model. | 2012 | Details |