Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07191 | 32587654 | J Clin Med Res | Associations Between Cannabis Use, Abdominal Fat Phenotypes and Insulin Traits. | 2020 | Details |
| A07199 | 32585242 | Life Sci | IGFBP5 modulates lipid metabolism and insulin sensitivity through activating AMPK pathway in non-alcoholic fatty liver disease. | 2020 | Details |
| A07203 | 32583961 | Clin Transl Sci | Evolving Role for Pharmacotherapy in NAFLD/NASH. | 2020 | Details |
| A07208 | 32582754 | Front Nutr | PTEN: A Thrifty Gene That Causes Disease in Times of Plenty? | 2020 | Details |
| A07212 | 32580141 | EBioMedicine | Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans. | 2020 | Details |
| A07219 | 32577775 | Inflamm Res | Pathobiological and molecular connections involved in the high fructose and high fat diet induced diabetes associated nonalcoholic fatty liver disease. | 2020 | Details |
| A07224 | 32576036 | Endocr Pract | ROLE OF ANDROGEN IN LIVER FAT CONTENT IN WOMEN: METABOLICALLY ADVANTAGEOUS OR DISADVANTAGEOUS? | 2020 | Details |
| A07231 | 32573497 | JCI Insight | Leptin decreases de novo lipogenesis in patients with lipodystrophy. | 2020 | Details |
| A07244 | 32569680 | Metabolism | Metabolic liver disease in diabetes - From mechanisms to clinical trials. | 2020 | Details |
| A07247 | 32568734 | J Pediatr Endocrinol Metab | Definition and early diagnosis of metabolic syndrome in children. | 2020 | Details |
| A07250 | 32566571 | Ann Transl Med | Association between ratio of γ-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study. | 2020 | Details |
| A07260 | 32562818 | Pharmacol Res | ZLY032, the first-in-class dual FFA1/PPARδ agonist, improves glucolipid metabolism and alleviates hepatic fibrosis. | 2020 | Details |
| A07267 | 32559839 | Biomed Pharmacother | Ling-gui-zhu-gan decoction alleviates hepatic steatosis through SOCS2 modification by N6-methyladenosine. | 2020 | Details |
| A07269 | 32559586 | J Nutr Biochem | Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice. | 2020 | Details |
| A07270 | 32559194 | PLoS Med | Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts. | 2020 | Details |
| A07273 | 32559006 | Liver Int | Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. | 2020 | Details |
| A07283 | 32555989 | Arch Endocrinol Metab | Nonalcoholic fatty liver disease in women with polycystic ovary syndrome: associated factors and noninvasive fibrosis staging in a single Brazilian center. | 2020 | Details |
| A07287 | 32554245 | Biomed Pharmacother | 1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice. | 2020 | Details |
| A07289 | 32553943 | Alcohol | Effects of low ethanol consumption on nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A07296 | 32552211 | Expert Rev Gastroenterol Hepatol | Genetics and epigenetics purpose in nonalcoholic fatty liver disease. | 2020 | Details |
| A07299 | 32550751 | World J Gastroenterol | Post-transplant diabetes mellitus and preexisting liver disease - a bidirectional relationship affecting treatment and management. | 2020 | Details |
| A07300 | 32550210 | J Diabetes Metab Disord | Mediterranean diet for patients with non-alcoholic fatty liver disease, a systematic review and meta-analysis of observational and clinical investigations. | 2020 | Details |
| A07310 | 32545215 | Diagnostics (Basel) | Could SCGF-Beta Levels Be Associated with Inflammation Markers and Insulin Resistance in Male Patients Suffering from Obesity-Related NAFLD? | 2020 | Details |
| A07318 | 32540813 | Ann Biol Clin (Paris) | [Mutltifaceted biological roles of adiponectin]. | 2020 | Details |
| A07328 | 32535386 | Biomed Pharmacother | HCBP6 deficiency exacerbates glucose and lipid metabolism disorders in non-alcoholic fatty liver mice. | 2020 | Details |
| A07330 | 32534588 | Cardiovasc Diabetol | Non-alcoholic steatohepatitis and progression of carotid atherosclerosis in patients with type 2 diabetes: a Korean cohort study. | 2020 | Details |
| A07333 | 32533233 | Pathologe | [Histopathological diagnosis and differential diagnosis of nonalcoholic fatty liver disease]. | 2020 | Details |
| A07335 | 32532003 | Int J Mol Sci | Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men. | 2020 | Details |
| A07340 | 32531370 | Int J Biol Macromol | The protective effects of walnut green husk polysaccharide on liver injury, vascular endothelial dysfunction and disorder of gut microbiota in high fructose-induced mice. | 2020 | Details |
| A07349 | 32529412 | Diabetologia | Exercise and metabolic health: beyond skeletal muscle. | 2020 | Details |
| A07351 | 32528557 | Diabetol Metab Syndr | Association of [1H]-MRS quantified liver fat content with glucose metabolism status. | 2020 | Details |
| A07375 | 32522273 | Trials | Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial. | 2020 | Details |
| A07382 | 32519009 | Curr Diab Rep | Purine Metabolite Signatures and Type 2 Diabetes: Innocent Bystanders or Actionable Items? | 2020 | Details |
| A07385 | 32518275 | Sci Rep | The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07387 | 32518225 | Nutr Diabetes | Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats. | 2020 | Details |
| A07394 | 32515880 | Liver Int | Mechanisms for increased risk of diabetes in chronic liver diseases. | 2020 | Details |
| A07401 | 32514450 | JGH Open | Sodium-glucose cotransporter 2 inhibition does not reduce hepatic steatosis in overweight, insulin-resistant patients without type 2 diabetes. | 2019 | Details |
| A07405 | 32514025 | Nutr Diabetes | Association between famine exposure in early life with insulin resistance and beta cell dysfunction in adulthood. | 2020 | Details |
| A07407 | 32512752 | Nutrients | The Effect of Three Mediterranean Diets on Remnant Cholesterol and Non-Alcoholic Fatty Liver Disease: A Secondary Analysis. | 2020 | Details |
| A07408 | 32512581 | PLoS One | Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet. | 2020 | Details |
| A07410 | 32512072 | Toxicol Appl Pharmacol | Diosmin ameliorates inflammation, insulin resistance, and fibrosis in an experimental model of non-alcoholic steatohepatitis in rats. | 2020 | Details |
| A07415 | 32508918 | Int J Endocrinol | Neck Circumference is an Effective Supplement for Nonalcoholic Fatty Liver Disease Screening in a Community-Based Population. | 2020 | Details |
| A07421 | 32507439 | Complement Ther Med | Effects of garlic powder supplementation on insulin resistance, oxidative stress, and body composition in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial. | 2020 | Details |
| A07424 | 32505776 | Clin Chim Acta | Intestinal microbiota-farnesoid X receptor axis in metabolic diseases. | 2020 | Details |
| A07426 | 32504921 | Biomed Pharmacother | The influence of probiotics on bile acids in diseases and aging. | 2020 | Details |
| A07430 | 32502637 | Pharmacol Res | Molecular mechanisms of hepatic insulin resistance in nonalcoholic fatty liver disease and potential treatment strategies. | 2020 | Details |
| A07432 | 32499918 | Gastroenterol Rep (Oxf) | Effect of Helicobacter pylori-eradication therapy on hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomized-controlled pilot study. | 2019 | Details |
| A07441 | 32495731 | Proc Nutr Soc | Report of a member-led meeting: how stable isotope techniques can enhance human nutrition research. | 2020 | Details |
| A07449 | 32491288 | Physiol Int | Betanin effect on PPAR-α and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis. | 2020 | Details |
| A07454 | 32489856 | Integr Med Res | Herbal formulation MIT ameliorates high-fat diet-induced non-alcoholic fatty liver disease. | 2020 | Details |
| A07457 | 32488147 | Sci Rep | Decrease in waist-to-hip ratio reduced the development of chronic kidney disease in non-obese non-alcoholic fatty liver disease. | 2020 | Details |
| A07462 | 32485838 | Int J Mol Sci | The Role of Insulin Resistance and Diabetes in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07468 | 32483549 | Pediatr Gastroenterol Hepatol Nutr | A Nomogram for Predicting Non-Alcoholic Fatty Liver Disease in Obese Children. | 2020 | Details |
| A07470 | 32483260 | Sci Rep | Endothelial dysfunction in nonalcoholic steatohepatitis with low cardiac disease risk. | 2020 | Details |
| A07481 | 32477116 | Front Pharmacol | Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application. | 2020 | Details |
| A07491 | 32475757 | Pancreatology | Liver and pancreas: 'Castor and Pollux' regarding the relationship between hepatic steatosis and pancreas exocrine insufficiency. | 2020 | Details |
| A07497 | 32472598 | FASEB J | Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr-/- .Leiden mice. | 2020 | Details |
| A07500 | 32472367 | Curr Nutr Rep | Kefir in the Prevention and Treatment of Obesity and Metabolic Disorders. | 2020 | Details |
| A07506 | 32467498 | Am J Ther | How to Reduce Cardiovascular Risk in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07515 | 32461046 | Clin Chim Acta | Emerging role of Insig-1 in lipid metabolism and lipid disorders. | 2020 | Details |
| A07521 | 32460191 | Biomed Pharmacother | Sodium acetate-mediated inhibition of histone deacetylase alleviates hepatic lipid dysregulation and its accompanied injury in streptozotocin-nicotinamide-induced diabetic rats. | 2020 | Details |
| A07522 | 32460140 | Atherosclerosis | Hepatocyte-like cells derived from induced pluripotent stem cells: A versatile tool to understand lipid disorders. | 2020 | Details |
| A07525 | 32455208 | ACS Omega | Ginsenoside Rg1 Regulates Liver Lipid Factor Metabolism in NAFLD Model Rats. | 2020 | Details |
| A07531 | 32454173 | J Ethnopharmacol | An unbiased lipidomics approach identifies key lipid molecules as potential therapeutic targets of Dohongsamul-tang against non-alcoholic fatty liver diseases in a mouse model of obesity. | 2020 | Details |
| A07542 | 32450149 | Gastroenterology | Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122. | 2020 | Details |
| A07544 | 32448788 | BMJ Open Diabetes Res Care | Effects of a multifactorial ecosustainable isocaloric diet on liver fat in patients with type 2 diabetes: randomized clinical trial. | 2020 | Details |
| A07564 | 32442908 | Cytokine | Gastric banding-associated weight loss diminishes hepatic Tsukushi expression. | 2020 | Details |
| A07566 | 32440840 | J Nephrol | Therapeutic implications of shared mechanisms in non-alcoholic fatty liver disease and chronic kidney disease. | 2020 | Details |
| A07570 | 32440483 | Adv Sci (Weinh) | Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder. | 2020 | Details |
| A07575 | 32438959 | Biomed Environ Sci | Peripheral Artery Disease and Risk of Fibrosis Deterioration in Nonalcoholic Fatty Liver Disease: A Prospective Investigation. | 2020 | Details |
| A07599 | 32429590 | Nutrients | Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance. | 2020 | Details |
| A07601 | 32429274 | Nutrients | The Protective Effect of Cynara Cardunculus Extract in Diet-Induced NAFLD: Involvement of OCTN1 and OCTN2 Transporter Subfamily. | 2020 | Details |
| A07602 | 32428560 | Biochim Biophys Acta Mol Basis Dis | Mitochondrial dysfunction in metabolic syndrome. | 2020 | Details |
| A07626 | 32415687 | Lipids | Relationships between Very Low-Density Lipoproteins-Ceramides, -Diacylglycerols, and -Triacylglycerols in Insulin-Resistant Men. | 2020 | Details |
| A07631 | 32414691 | J Pharmacol Sci | Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet. | 2020 | Details |
| A07643 | 32410680 | Lipids Health Dis | Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio. | 2020 | Details |
| A07646 | 32410310 | Liver Int | Objectively measured sedentary time, physical activity and liver enzyme elevations in US Hispanics/Latinos. | 2020 | Details |
| A07651 | 32408667 | Int J Environ Res Public Health | The Bisphenol A Induced Oxidative Stress in Non-Alcoholic Fatty Liver Disease Male Patients: A Clinical Strategy to Antagonize the Progression of the Disease. | 2020 | Details |
| A07652 | 32408171 | iScience | High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. | 2020 | Details |
| A07664 | 32404278 | Biochim Biophys Acta Mol Cell Biol Lipids | Niacin increases diet-induced hepatic steatosis in B6129 mice. | 2020 | Details |
| A07667 | 32403305 | Antioxidants (Basel) | The Hepatoprotective Effect of Taurisolo, a Nutraceutical Enriched in Resveratrol and Polyphenols, Involves Activation of Mitochondrial Metabolism in Mice Liver. | 2020 | Details |
| A07678 | 32396388 | Am J Physiol Endocrinol Metab | β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro. | 2020 | Details |
| A07690 | 32390388 | Clin Lab | Plasma miR-513a-5p as a Potential Biomarker for Diagnosis of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus Patients. | 2020 | Details |
| A07697 | 32388250 | J Nutr Biochem | Targeting the gut microbiota with resveratrol: a demonstration of novel evidence for the management of hepatic steatosis. | 2020 | Details |
| A07699 | 32387461 | J Ethnopharmacol | Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress. | 2020 | Details |
| A07702 | 32386450 | Liver Int | The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue. | 2020 | Details |
| A07704 | 32384593 | Nutrients | Beyond Body Weight-Loss: Dietary Strategies Targeting Intrahepatic Fat in NAFLD. | 2020 | Details |
| A07711 | 32382087 | Sci Rep | Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance. | 2020 | Details |
| A07734 | 32372191 | Dig Dis Sci | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. | 2020 | Details |
| A07736 | 32370702 | Protein Pept Lett | Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions. | 2020 | Details |
| A07738 | 32369900 | J Clin Med | Inhibition of Protein-tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress. | 2020 | Details |
| A07744 | 32367624 | Pediatr Obes | Increased atherogenic lipoprotein profile in children with non-alcoholic steatohepatitis. | 2020 | Details |
| A07748 | 32365632 | Cells | L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. | 2020 | Details |
| A07751 | 32365055 | J Clin Invest | Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes. | 2020 | Details |
| A07752 | 32364539 | J Clin Invest | Insulin-stimulated lipogenesis gets an epigenetic makeover. | 2020 | Details |
| A07753 | 32363890 | Am J Physiol Gastrointest Liver Physiol | Immune modulating effects of additional supplementation of estradiol combined with testosterone in murine testosterone-deficient NAFLD model. | 2020 | Details |
| A07755 | 32363679 | Diabetes Obes Metab | Intrahepatic fat, irrespective of ethnicity, is associated with reduced endogenous insulin clearance and hepatic insulin resistance in obese youths: A cross-sectional and longitudinal study from the Yale Pediatric NAFLD cohort. | 2020 | Details |
| A07756 | 32363320 | Hepatol Commun | Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07758 | 32363318 | Hepatol Commun | Differential Associations of Circulating MicroRNAs With Pathogenic Factors in NAFLD. | 2020 | Details |
| A07759 | 32362966 | Gastroenterology Res | Benefits of the Therapy With Abexol in Patients With Non-Alcoholic Fatty Liver Disease. | 2020 | Details |