Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08894 | 31949886 | Oxid Med Cell Longev | Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism. | 2019 | Details |
| A08913 | 31941015 | Int J Mol Sci | Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences. | 2020 | Details |
| A08923 | 31936799 | Cells | Diet, Gut Microbiota and Non-Alcoholic Fatty Liver Disease: Three Parts of the Same Axis. | 2020 | Details |
| A08928 | 31935149 | Crit Rev Clin Lab Sci | Fructose and hepatic insulin resistance. | 2020 | Details |
| A08934 | 31931541 | Z Gastroenterol | A young patient with type 2 diabetes associated non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. | 2020 | Details |
| A08938 | 31930835 | Pak J Biol Sci | FICK-3 Score Combining Fibrosis-4, Insulin Resistance and Cytokeratin-18 in Predicting Non-alcoholic Steatohepatitis in NAFLD Egyptian Patients. | 2019 | Details |
| A08945 | 31929840 | Dis Markers | Beta-3-adrenergic Receptor rs4994 Polymorphism Is a Potential Biomarker for the Development of Nonalcoholic Fatty Liver Disease in Overweight/Obese Individuals. | 2019 | Details |
| A08948 | 31928475 | Expert Opin Investig Drugs | NASH (nonalcoholic steatohepatitis), diabetes, and macrovascular disease: multiple chronic conditions and a potential treatment at the metabolic root. | 2020 | Details |
| A08954 | 31926984 | J Ethnopharmacol | Sweroside ameliorates NAFLD in high-fat diet induced obese mice through the regulation of lipid metabolism and inflammatory response. | 2020 | Details |
| A08963 | 31923578 | Diabetes Metab | Efficacy and safety of anti-hyperglycaemic drugs in patients with non-alcoholic fatty liver disease with or without diabetes: An updated systematic review of randomized controlled trials. | 2020 | Details |
| A08971 | 31920962 | Front Endocrinol (Lausanne) | Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases. | 2019 | Details |
| A08976 | 31918923 | Mol Metab | Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis. | 2019 | Details |
| A08984 | 31915606 | J Clin Transl Hepatol | Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09009 | 31905727 | Nutrients | Intestinal Fructose and Glucose Metabolism in Health and Disease. | 2019 | Details |
| A09026 | 31899984 | Expert Opin Investig Drugs | Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis. | 2020 | Details |
| A09037 | 31894585 | J Food Biochem | Royal jelly attenuates nonalcoholic fatty liver disease by inhibiting oxidative stress and regulating the expression of circadian genes in ovariectomized rats. | 2020 | Details |
| A09053 | 31888241 | Nutrients | Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial. | 2019 | Details |
| A09069 | 31885541 | Gastroenterol Res Pract | Systematic Review with Meta-Analysis: The Effects of Probiotics in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09070 | 31885103 | Fundam Clin Pharmacol | Comparative effectiveness of phosphodiesterase 3, 4, and 5 inhibitors in amelioration of high-fat diet-induced nonalcoholic fatty liver in rats. | 2020 | Details |
| A09080 | 31882566 | Diabetes | The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH. | 2019 | Details |
| A09082 | 31882273 | J Diabetes Complications | Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements. | 2019 | Details |
| A09086 | 31881272 | Pharmacol Res | The gut-liver-kidney axis: Novel regulator of fatty liver associated chronic kidney disease. | 2019 | Details |
| A09098 | 31877412 | Mol Ther Nucleic Acids | Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. | 2019 | Details |
| A09108 | 31870938 | Peptides | Endogenously released GIP reduces and GLP-1 increases hepatic insulin extraction. | 2019 | Details |
| A09113 | 31870087 | Korean J Pediatr | Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity. | 2019 | Details |
| A09127 | 31865317 | Dig Dis | Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. | 2019 | Details |
| A09130 | 31863731 | Exp Neurol | Hepatic dysfunction after spinal cord injury: A vicious cycle of central and peripheral pathology? | 2019 | Details |
| A09134 | 31862486 | J Hepatol | Clinical validation of the FLIP algorithm and the SAF score in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A09147 | 31858390 | Endocrine | Noninvasive assessment of hepatic steatosis and fibrosis in patients with severe obesity. | 2019 | Details |
| A09152 | 31857090 | Chem Biol Interact | Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity. | 2019 | Details |
| A09153 | 31856189 | PLoS One | Nonalcoholic fatty liver disease and hepatic fibrosis among perinatally HIV-monoinfected Asian adolescents receiving antiretroviral therapy. | 2019 | Details |
| A09157 | 31852748 | J Investig Med | Relationship between non-alcoholic fatty liver disease during pregnancy and abnormal glucose metabolism during and after pregnancy. | 2019 | Details |
| A09171 | 31850288 | Front Pediatr | Metabolic Syndrome Is Associated With Advanced Liver Fibrosis Among Pediatric Patients With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09175 | 31847612 | Expert Opin Investig Drugs | The molecular basis for current targets of NASH therapies. | 2019 | Details |
| A09178 | 31847157 | Nutrients | Sarcopoterium spinosum Inhibited the Development of Non-Alcoholic Steatosis and Steatohepatitis in Mice. | 2019 | Details |
| A09184 | 31845054 | J Gastroenterol | Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives. | 2019 | Details |
| A09186 | 31843573 | J Ethnopharmacol | San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice models. | 2019 | Details |
| A09193 | 31840865 | Nutr Clin Pract | Evolution of NAFLD and Its Management. | 2019 | Details |
| A09194 | 31840531 | Clin Appl Thromb Hemost | Nonalcoholic Fatty Liver Disease and Thrombocytopenia III: Its Association With Insulin Resistance. | 2020 | Details |
| A09196 | 31839747 | Int J Med Sci | PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell. | 2019 | Details |
| A09203 | 31837337 | Life Sci | Prefrontal cortex inflammation and liver pathologies accompany cognitive and motor deficits following Western diet consumption in non-obese female mice. | 2019 | Details |
| A09206 | 31836013 | BMC Complement Altern Med | Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice. | 2019 | Details |
| A09216 | 31833787 | Epigenomics | Rat liver epigenome programing by perinatal exposure to 2,2',4'4'-tetrabromodiphenyl ether. | 2019 | Details |
| A09218 | 31832576 | Hepatol Commun | Insulin Resistance and Genetic Risk Predict Liver-Related Outcomes and Death in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09222 | 31832001 | World J Gastroenterol | LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway. | 2019 | Details |
| A09232 | 31826069 | J Gastrointestin Liver Dis | PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes. | 2019 | Details |
| A09242 | 31821039 | Am J Physiol Endocrinol Metab | Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism. | 2019 | Details |
| A09249 | 31817648 | Nutrients | High Protein Diet and Metabolic Plasticity in Non-Alcoholic Fatty Liver Disease: Myths and Truths. | 2019 | Details |
| A09250 | 31817623 | J Clin Med | Higher Sodium Intake Assessed by 24 Hour Urinary Sodium Excretion Is Associated with Non-Alcoholic Fatty Liver Disease: The PREVEND Cohort Study. | 2019 | Details |
| A09255 | 31816412 | Biochim Biophys Acta Mol Cell Biol Lipids | Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition. | 2019 | Details |
| A09259 | 31814783 | Hepat Med | A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A09272 | 31809318 | Chin Med J (Engl) | Association of leukocyte telomere length with non-alcoholic fatty liver disease in patients with type 2 diabetes. | 2019 | Details |
| A09278 | 31808322 | J Korean Med Sci | Correlation of Clinical and Histopathologic Parameters with Ultrasonographic Grades in Pediatric Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09280 | 31808097 | Environ Sci Pollut Res Int | Could phthalates exposure contribute to the development of metabolic syndrome and liver disease in humans? | 2019 | Details |
| A09281 | 31807383 | Cureus | Effect of Non-alcoholic Fatty Liver Disease on Transaminase Levels and Transient Elastography in Patients with Chronic Hepatitis B. | 2019 | Details |
| A09284 | 31805951 | Lipids Health Dis | Target genes associated with lipid and glucose metabolism in non-alcoholic fatty liver disease. | 2019 | Details |
| A09285 | 31805752 | Molecules | Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models. | 2019 | Details |
| A09287 | 31805072 | PLoS One | Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Leprdb/J mouse model of non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A09288 | 31805015 | J Clin Invest | Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease. | 2020 | Details |
| A09292 | 31803542 | PeerJ | Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice. | 2019 | Details |
| A09293 | 31803485 | BMJ Open Diabetes Res Care | Determinants of longitudinal change in insulin clearance: the Prospective Metabolism and Islet Cell Evaluation cohort. | 2019 | Details |
| A09294 | 31803464 | Ther Adv Endocrinol Metab | Reduced physical activity in young and older adults: metabolic and musculoskeletal implications. | 2019 | Details |
| A09296 | 31801616 | J Transl Med | Microbiota, type 2 diabetes and non-alcoholic fatty liver disease: protocol of an observational study. | 2019 | Details |
| A09300 | 31800592 | PLoS One | Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. | 2019 | Details |
| A09306 | 31797544 | Mol Nutr Food Res | Vitamin D Deficiency Induces Insulin Resistance and Re-Supplementation Attenuates Hepatic Glucose Output via the PI3K-AKT-FOXO1 Mediated Pathway. | 2020 | Details |
| A09308 | 31796953 | Am J Clin Nutr | Metabolic effects of a prolonged, very-high-dose dietary fructose challenge in healthy subjects. | 2020 | Details |
| A09310 | 31795988 | BMC Public Health | First-degree family history of diabetes and its relationship with serum osteocalcin levels independent of liver fat content in a non-diabetic Chinese cohort. | 2019 | Details |
| A09322 | 31790897 | Phytomedicine | Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates insulin resistance and hepatic steatosis via PI3K/Akt/GSK3β pathway. | 2019 | Details |
| A09324 | 31790829 | Free Radic Biol Med | Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice. | 2019 | Details |
| A09345 | 31783635 | Nutrients | Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents: A Systematic Review. | 2019 | Details |
| A09349 | 31782258 | Physiol Rep | SGLT2 inhibitor ipragliflozin alone and combined with pioglitazone prevents progression of nonalcoholic steatohepatitis in a type 2 diabetes rodent model. | 2019 | Details |
| A09356 | 31780766 | Sci Rep | Sodium fluorocitrate having inhibitory effect on fatty acid uptake ameliorates high fat diet-induced non-alcoholic fatty liver disease in C57BL/6J mice. | 2019 | Details |
| A09358 | 31779730 | Br J Nutr | Dietary protein insufficiency: an important consideration in fatty liver disease? | 2019 | Details |
| A09361 | 31777896 | Food Funct | Attenuation of metabolic syndrome in the ob/ob mouse model by resistant starch intervention is dose dependent. | 2019 | Details |
| A09369 | 31775341 | Int J Mol Sci | Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction. | 2019 | Details |
| A09373 | 31771682 | Br J Nutr | Crude extract of Camellia oleifera pomace ameliorates the progression of non-alcoholic fatty liver disease via decreasing fat accumulation, insulin resistance and inflammation. | 2019 | Details |
| A09381 | 31769484 | Clin Sci (Lond) | Dapagliflozin not only improves hepatic injury and pancreatic endoplasmic reticulum stress, but also induces hepatic gluconeogenic enzymes expression in obese rats. | 2019 | Details |
| A09383 | 31767938 | Sci Rep | Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease. | 2019 | Details |
| A09386 | 31766373 | J Clin Med | Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review. | 2019 | Details |
| A09387 | 31765666 | Metabolism | Low levels of total and high-molecular-weight adiponectin may predict non-alcoholic fatty liver in Korean adults. | 2019 | Details |
| A09393 | 31762148 | Liver Int | Dietary fatty acid oxidation is decreased in non-alcoholic fatty liver disease: A palmitate breath test study. | 2019 | Details |
| A09397 | 31760464 | Cell Mol Life Sci | Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis. | 2020 | Details |
| A09399 | 31760308 | J Nutr Biochem | Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice. | 2019 | Details |
| A09401 | 31759197 | J Nutr Biochem | Mitigation of nonalcoholic fatty liver disease in high-fat-fed mice by the combination of decaffeinated green tea extract and voluntary exercise. | 2019 | Details |
| A09405 | 31758951 | Metabolism | Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. | 2019 | Details |
| A09415 | 31757735 | Presse Med | [Pharmacological treatment of NASH]. | 2019 | Details |
| A09417 | 31757727 | Presse Med | [Nutritional Management of Nonalcoholic fatty liver disease (NAFLD)]. | 2019 | Details |
| A09425 | 31754954 | Hormones (Athens) | Obese boys with low concentrations of high-density lipoprotein cholesterol are at greater risk of hepatosteatosis. | 2019 | Details |
| A09428 | 31754142 | Sci Rep | New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery. | 2019 | Details |
| A09444 | 31746482 | Aliment Pharmacol Ther | Systematic review: chronic viral hepatitis and metabolic derangement. | 2019 | Details |
| A09460 | 31737175 | Oxid Med Cell Longev | Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients. | 2019 | Details |
| A09463 | 31734856 | Intern Emerg Med | Liver alterations in anorexia nervosa are not caused by insulin resistance. | 2019 | Details |
| A09505 | 31717414 | Int J Mol Sci | Lipid Related Genes Altered in NASH Connect Inflammation in Liver Pathogenesis Progression to HCC: A Canonical Pathway. | 2019 | Details |
| A09508 | 31717271 | J Clin Med | The Association between SOCS1-1656G>A Polymorphism, Insulin Resistance and Obesity in Nonalcoholic Fatty Liver Disease (NAFLD) Patients. | 2019 | Details |
| A09514 | 31714387 | Eur J Gastroenterol Hepatol | Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome. | 2020 | Details |
| A09535 | 31705444 | Hepatol Int | Sarcopenia and fatty liver disease. | 2019 | Details |
| A09538 | 31703079 | PLoS One | Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation. | 2019 | Details |
| A09539 | 31702809 | Mol Med Rep | Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet. | 2019 | Details |
| A09548 | 31697972 | J Hepatol | Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study. | 2019 | Details |
| A09549 | 31697646 | Aging (Albany NY) | Catalpol induces autophagy and attenuates liver steatosis in ob/ob and high-fat diet-induced obese mice. | 2019 | Details |