Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Tumor necrosis factor1477 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A49592 | 35700593 | Nutrition | Short-term high-fat and high-carbohydrate diets increase susceptibility to liver injury by inducing hepatic procoagulant and proinflammatory conditions with different balances. | 2022 | Details |
| A49674 | 35673882 | J Food Sci | Cornus officinalis vinegar reduces body weight and attenuates hepatic steatosis in mouse model of nonalcoholic fatty liver disease. | 2022 | Details |
| A49736 | 35654350 | J Ethnopharmacol | Danhe granule ameliorates nonalcoholic steatohepatitis and fibrosis in rats by inhibiting ceramide de novo synthesis related to CerS6 and CerK. | 2022 | Details |
| A49885 | 35608965 | Eur J Neurol | Nonalcoholic fatty liver disease, serum cytokines, and dementia among rural-dwelling older adults in China: A population-based study. | 2022 | Details |
| A49898 | 35604436 | Rheumatol Int | Treatment of rheumatoid arthritis with conventional, targeted and biological disease-modifying antirheumatic drugs in the setting of liver injury and non-alcoholic fatty liver disease. | 2022 | Details |
| A49903 | 35603224 | Front Immunol | Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49922 | 35594708 | Biomed Pharmacother | Exogenous administration of unacylated ghrelin attenuates hepatic steatosis in high-fat diet-fed rats by modulating glucose homeostasis, lipogenesis, oxidative stress, and endoplasmic reticulum stress. | 2022 | Details |
| A49994 | 35568228 | Life Sci | Protective effects of maslinic acid on high fat diet-induced liver injury in mice. | 2022 | Details |
| A50007 | 35565666 | Nutrients | Myristica fragrans Extract Regulates Gut Microbes and Metabolites to Attenuate Hepatic Inflammation and Lipid Metabolism Disorders via the AhR-FAS and NF-κB Signaling Pathways in Mice with Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50069 | 35536225 | J Agric Food Chem | Caffeine Ameliorates AKT-Driven Nonalcoholic Steatohepatitis by Suppressing De Novo Lipogenesis and MyD88 Palmitoylation. | 2022 | Details |
| A50085 | 35532955 | Metab Syndr Relat Disord | Nonalcoholic Fatty Liver Disease Patients Exhibit Reduced CD47 and Increased Sphingosine, Cholesterol, and Monocyte Chemoattractant Protein-1 Levels in the Erythrocyte Membranes. | 2022 | Details |
| A50090 | 35531696 | Zhongguo Zhong Yao Za Zhi | [Di'ao Xinxuekang alleviates non-alcoholic steatohepatitis in mice by up-regulating Nrf2/HO-1 signaling pathway]. | 2022 | Details |
| A50110 | 35522866 | Wiad Lek | FEATURES OF INTESTINAL MICROBIOTA IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE: EFFECTS ON MARKERS OF INFLAMMATION AND HEPATIC STEATOSIS. | 2022 | Details |
| A50112 | 35521658 | Antioxid Redox Signal | RGS7-ATF3-Tip60 Complex Promotes Hepatic Steatosis and Fibrosis by Directly Inducing TNFα. | 2022 | Details |
| A50274 | 35447548 | Biomed Pharmacother | Downregulation of hepatic fat accumulation, inflammation and fibrosis by nerolidol in purpose built western-diet-induced multiple-hit pathogenesis of NASH animal model. | 2022 | Details |
| A50310 | 35436630 | Biochem Biophys Res Commun | Hydrochloride Berberine ameliorates alcohol-induced liver injury by regulating inflammation and lipid metabolism. | 2022 | Details |
| A50370 | 35413806 | BMC Gastroenterol | Prevalence and predictors of non-alcoholic liver disease on MRI among patients with Crohn's disease. | 2022 | Details |
| A50373 | 35413066 | PLoS One | Anti-inflammatory function of apolipoprotein B-depleted plasma is impaired in non-alcoholic fatty liver disease. | 2022 | Details |
| A50387 | 35408923 | Int J Mol Sci | The Beneficial Effects of Triterpenic Acid and Acteoside in an In Vitro Model of Nonalcoholic Steatohepatitis (NASH). | 2022 | Details |
| A50758 | 35276916 | Nutrients | A Lard and Soybean Oil Mixture Alleviates Low-Fat-High-Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A50771 | 35272137 | Biomed Pharmacother | The contribution of sterile inflammation to the fatty liver disease and the potential therapies. | 2022 | Details |
| A50812 | 35212695 | Food Funct | Citrus depressa Hayata peel ameliorates nonalcoholic fatty liver and modulates the activity of hepatic drug-metabolizing enzymes and transporters in rats fed a high-fat diet. | 2022 | Details |
| A50957 | 35520738 | RSC Adv | GVS-12 attenuates non-alcoholic steatohepatitis by suppressing inflammatory responses via PPARγ/STAT3 signaling pathways. | 2019 | Details |
| A50966 | 35548751 | RSC Adv | Therapeutic efficacy of polydatin for nonalcoholic fatty liver disease via regulating inflammatory response in obese mice. | 2018 | Details |
| A51080 | 15685567 | Gastroenterology | Adiponectin--tipping the scales from NAFLD to NASH? | 2005 | Details |
| A51145 | 35491473 | Alcohol Clin Exp Res | Chronic ethanol consumption plus an atherogenic diet cause metabolic steatohepatitis with advanced liver fibrosis in apolipoprotein E/low-density lipoprotein receptor double-knockout mice. | 2022 | Details |
| A51348 | 35419738 | Inflammation | Melatonin Attenuates Inflammation, Oxidative Stress, and DNA Damage in Mice with Nonalcoholic Steatohepatitis Induced by a Methionine- and Choline-Deficient Diet. | 2022 | Details |
| A51388 | 30623143 | JACC Basic Transl Sci | The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE-/- and LDLr-/- Mice by a Mechanism That Includes Inflammatory Pathways. | 2018 | Details |
| A51469 | 32426239 | Toxicol Rep | MicroRNAs and Xenobiotic Toxicity: An Overview. | 2020 | Details |
| A51547 | 35359076 | Zhonghua Gan Zang Bing Za Zhi | [Berberine alleviates programmed necrosis of metabolic-associated fatty liver disease via activating Nrf2 pathway in mice]. | 2022 | Details |
| A51760 | 34303283 | Tissue Cell | CTRP3 ameliorates fructose-induced metabolic associated fatty liver disease via inhibition of xanthine oxidase-associated oxidative stress. | 2021 | Details |
| A51774 | 34219348 | Liver Int | Anti-TNFα treatment in Crohn's disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status. | 2021 | Details |
| A51842 | 33777186 | Exp Ther Med | Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic-associated fatty liver disease in mice. | 2021 | Details |
| A51851 | 33680863 | Toxicol Rep | Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy. | 2021 | Details |
| A52019 | 32231246 | Cell Death Differ | OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. | 2020 | Details |
| A52059 | 31778751 | J Hepatol | Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF. | 2019 | Details |
| A52080 | 31573846 | Am J Physiol Endocrinol Metab | The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation. | 2019 | Details |
| A52085 | 31495623 | J Dairy Sci | Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows. | 2019 | Details |
| A52126 | 30954078 | Lipids Health Dis | Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver. | 2019 | Details |
| A52144 | 30723473 | Front Immunol | Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice. | 2019 | Details |
| A52156 | 30597839 | Medicines (Basel) | Chicken Protein Hydrolysates Have Anti-Inflammatory Effects on High-Fat Diet Induced Obesity in Mice. | 2018 | Details |
| A52287 | 29115530 | Mol Med Rep | Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats. | 2017 | Details |
| A52431 | 27197570 | Mol Biosyst | Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming. | 2016 | Details |
| A52463 | 26838266 | Nat Commun | PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. | 2016 | Details |
| A52475 | 26579439 | Acta Pharm Sin B | Bile acid nuclear receptor FXR and digestive system diseases. | 2015 | Details |
| A52525 | 26042203 | Mol Metab | Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. | 2015 | Details |
| A52622 | 24679404 | Animal | Reproductive tract inflammatory disease in postpartum dairy cows. | 2014 | Details |
| A52631 | 24486395 | Eur J Pharmacol | Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat. | 2014 | Details |
| A52635 | 24438728 | Prog Cardiovasc Dis | Overview of epidemiology and contribution of obesity to cardiovascular disease. | 2013 | Details |
| A52654 | 24117253 | Can J Physiol Pharmacol | Metabolic inflammation: role of cytokines in the crosstalk between adipose tissue and liver. | 2013 | Details |
| A52678 | 23687413 | World J Gastroenterol | Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats. | 2013 | Details |
| A52734 | 22664476 | J Clin Gastroenterol | Association of serum adipocytokines with insulin resistance and liver injury in patients with chronic hepatitis C genotype 4. | 2013 | Details |
| A52753 | 22428554 | J Immunotoxicol | Effects of pioglitazone and/or simvastatin on circulating TNFα and adiponectin levels in insulin resistance. | 2012 | Details |
| A52757 | 22405696 | J Nutr Biochem | Perinatal undernutrition alters intestinal alkaline phosphatase and its main transcription factors KLF4 and Cdx1 in adult offspring fed a high-fat diet. | 2012 | Details |
| A52774 | 22185842 | Am J Physiol Endocrinol Metab | Generation and characterization of a mouse model of the metabolic syndrome: apolipoprotein E and aromatase double knockout mice. | 2011 | Details |
| A52800 | 21725989 | Hepatology | Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. | 2011 | Details |
| A52841 | 20980637 | J Nutr | Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. | 2010 | Details |
| A52847 | 20824098 | PLoS One | Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. | 2010 | Details |
| A52881 | 20111014 | Obesity (Silver Spring) | The influence of a high-fat dietary environment in the fetal period on postnatal metabolic and immune function. | 2010 | Details |
| A52899 | 19809411 | Am J Gastroenterol | Interaction of adipokines and hepatitis B virus on histological liver injury in the Chinese. | 2009 | Details |
| A52907 | 19729476 | Am J Pathol | Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells. | 2009 | Details |
| A52917 | 19549757 | J Nutr | Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. | 2009 | Details |
| A52943 | 19201949 | Development | TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase. | 2009 | Details |
| A52951 | 19046738 | Clin Cornerstone | Endocrine functions of adipose tissue: focus on adiponectin. | 2008 | Details |
| A52996 | 18157836 | Hepatology | Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo. | 2008 | Details |
| A53002 | 17925761 | Gastroenterol Clin Biol | [Steatosis during chronic hepatitis C: the role of insulin resistance and viral factors]. | 2008 | Details |
| A53005 | 17901224 | Endocrinology | Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. | 2007 | Details |
| A53029 | 17016629 | Int J Mol Med | Hemostasis alterations in metabolic syndrome (review). | 2006 | Details |
| A53050 | 16477380 | Mol Cell Biochem | Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. | 2006 | Details |
| A53053 | 16424352 | Arterioscler Thromb Vasc Biol | Modulation of hepatic inflammatory risk markers of cardiovascular diseases by PPAR-alpha activators: clinical and experimental evidence. | 2006 | Details |
| A53074 | 15632045 | J Nucl Med | Regulation of hepatobiliary transport activity and noninvasive identification of cytokine-dependent liver inflammation. | 2005 | Details |
| A53090 | 15157941 | J Nutr Biochem | Effects of fish oil on hypertension, plasma lipids, and tumor necrosis factor-alpha in rats with sucrose-induced metabolic syndrome. | 2004 | Details |
| A53121 | 12127425 | J Hepatol | Leptin is essential for the hepatic fibrogenic response to chronic liver injury. | 2002 | Details |
| A53123 | 11921433 | Diabetes Metab Res Rev | The mode of action of thiazolidinediones. | 2002 | Details |
| A53151 | 9763522 | Arterioscler Thromb Vasc Biol | Sphingolipids in atherosclerosis and vascular biology. | 1998 | Details |
| A53164 | 7523453 | J Clin Invest | Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. | 1994 | Details |
| A53173 | 1907698 | J Surg Res | Polymyxin B reduces cecal flora, TNF production and hepatic steatosis during total parenteral nutrition in the rat. | 1991 | Details |