Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A16326 | 28458161 | Biomed Pharmacother | Total sesquiterpene glycosides from Loquat (Eriobotrya japonica) leaf alleviate high-fat diet induced non-alcoholic fatty liver disease through cytochrome P450 2E1 inhibition. | 2017 | Details |
| A16330 | 28456640 | Arch Biochem Biophys | Adrenic acid as an inflammation enhancer in non-alcoholic fatty liver disease. | 2017 | Details |
| A16332 | 28454924 | Toxicol Appl Pharmacol | Dual effect of silymarin on experimental non-alcoholic steatohepatitis induced by irinotecan. | 2017 | Details |
| A16339 | 28448552 | PLoS One | Transcriptomic analysis of the hepatic response to stress in the red cusk-eel (Genypterus chilensis): Insights into lipid metabolism, oxidative stress and liver steatosis. | 2017 | Details |
| A16360 | 28437890 | Biomed Pharmacother | Does propolis have any effect on non-alcoholic fatty liver disease? | 2017 | Details |
| A16366 | 28436198 | Mol Nutr Food Res | Effects of selenium on apoptosis and abnormal amino acid metabolism induced by excess fatty acid in isolated rat hepatocytes. | 2017 | Details |
| A16384 | 28425467 | Sci Rep | Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis. | 2017 | Details |
| A16389 | 28422962 | PLoS One | Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice. | 2017 | Details |
| A16394 | 28420094 | Nutrients | Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. | 2017 | Details |
| A16403 | 28415887 | Free Radic Res | Amelioration of late-onset hepatic steatosis in IDH2-deficient mice. | 2017 | Details |
| A16406 | 28414138 | Biochem Pharmacol | Apigenin, a modulator of PPARγ, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation. | 2017 | Details |
| A16414 | 28406477 | Cell Death Dis | miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice. | 2017 | Details |
| A16429 | 28395666 | Lipids Health Dis | Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice. | 2017 | Details |
| A16438 | 28388904 | BMC Complement Altern Med | Effect of traditional Chinese medicine formula Sinisan on chronic restraint stress-induced nonalcoholic fatty liver disease: a rat study. | 2017 | Details |
| A16442 | 28386616 | Food Funct | Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-α and Nrf2 activation, and NF-κB down-regulation. | 2017 | Details |
| A16463 | 28373762 | World J Gastroenterol | Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver disease. | 2017 | Details |
| A16478 | 28365312 | J Hepatol | Activating transcription factor 3 is a target molecule linking hepatic steatosis to impaired glucose homeostasis. | 2017 | Details |
| A16490 | 28358240 | Radiology | Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16515 | 28346237 | Curr Opin Gastroenterol | Current and future pharmacologic treatment of nonalcoholic steatohepatitis. | 2017 | Details |
| A16527 | 28335388 | Nutrients | A Combination of Flaxseed Oil and Astaxanthin Improves Hepatic Lipid Accumulation and Reduces Oxidative Stress in High Fat-Diet Fed Rats. | 2017 | Details |
| A16528 | 28335383 | Int J Mol Sci | A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets. | 2017 | Details |
| A16566 | 28303724 | Drug Metab Rev | Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. | 2017 | Details |
| A16568 | 28300221 | Sci Rep | Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. | 2017 | Details |
| A16591 | 28294699 | J Med Food | Chia Oil-Enriched Restructured Pork Effects on Oxidative and Inflammatory Status of Aged Rats Fed High Cholesterol/High Fat Diets. | 2017 | Details |
| A16600 | 28290049 | Curr Diab Rep | Type 2 Diabetes and Hepatocellular Carcinoma: Risk Factors and Pathogenesis. | 2017 | Details |
| A16605 | 28286271 | Biochem Biophys Res Commun | p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress. | 2017 | Details |
| A16628 | 28276774 | Expert Rev Clin Pharmacol | Pharmacological management of nonalcoholic fatty liver disease in type 2 diabetes. | 2017 | Details |
| A16633 | 28273805 | Nutrients | Fructose and NAFLD: The Multifaceted Aspects of  Fructose Metabolism. | 2017 | Details |
| A16636 | 28271632 | IUBMB Life | The role of insufficient copper in lipid synthesis and fatty-liver disease. | 2017 | Details |
| A16661 | 28257781 | Food Chem Toxicol | Diet high in fructose promotes liver steatosis and hepatocyte apoptosis in C57BL/6J female mice: Role of disturbed lipid homeostasis and increased oxidative stress. | 2017 | Details |
| A16665 | 28256569 | Mod Pathol | Aggressive non-alcoholic steatohepatitis following rapid weight loss and/or malnutrition. | 2017 | Details |
| A16669 | 28254666 | Biomed Pharmacother | Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c. | 2017 | Details |
| A16696 | 28239368 | Front Endocrinol (Lausanne) | Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease: Cellular and Mechanistic Insights. | 2017 | Details |
| A16705 | 28232481 | FASEB J | Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance. | 2017 | Details |
| A16729 | 28219837 | J Nutr Biochem | Chronic maternal calcium and 25-hydroxyvitamin D deficiency in Wistar rats programs abnormal hepatic gene expression leading to hepatic steatosis in female offspring. | 2017 | Details |
| A16732 | 28218651 | Int J Mol Sci | Proteome Characteristics of Non-Alcoholic Steatohepatitis Liver Tissue and Associated Hepatocellular Carcinomas. | 2017 | Details |
| A16737 | 28216552 | Mar Drugs | Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16743 | 28213091 | Toxicol Appl Pharmacol | Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity. | 2017 | Details |
| A16751 | 28210913 | Int Urol Nephrol | Dietary and commercialized fructose: Sweet or sour? | 2017 | Details |
| A16768 | 28192190 | J Hepatol | β7-Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis. | 2017 | Details |
| A16772 | 28189916 | J Nutr Biochem | Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver. | 2017 | Details |
| A16781 | 28180059 | Mol Metab | JNK at the crossroad of obesity, insulin resistance, and cell stress response. | 2016 | Details |
| A16788 | 28177674 | Can J Physiol Pharmacol | Exercise restores bioavailability of hydrogen sulfide and promotes autophagy influx in livers of mice fed with high-fat diet. | 2017 | Details |
| A16803 | 28164196 | Food Funct | Preventive effect of Silibinin in combination with Pu-erh tea extract on non-alcoholic fatty liver disease in ob/ob mice. | 2017 | Details |
| A16806 | 28162008 | Expert Rev Gastroenterol Hepatol | Clinical implications of understanding the association between oxidative stress and pediatric NAFLD. | 2017 | Details |
| A16809 | 28160259 | J Physiol Biochem | Protein malnutrition during fetal programming induces fatty liver in adult male offspring rats. | 2017 | Details |
| A16815 | 28157387 | Can J Physiol Pharmacol | Trigonelline attenuates hepatic complications and molecular alterations in high-fat high-fructose diet-induced insulin resistance in rats. | 2016 | Details |
| A16818 | 28154266 | Intern Med | The Serum Oxidative/Anti-oxidative Stress Balance Becomes Dysregulated in Patients with Non-alcoholic Steatohepatitis Associated with Hepatocellular Carcinoma. | 2017 | Details |
| A16822 | 28149843 | Ann Transl Med | Gamma-glutamyl transferase and cardiovascular disease. | 2016 | Details |
| A16831 | 28142119 | Biomed Pharmacother | Ginkgolide A ameliorates non-alcoholic fatty liver diseases on high fat diet mice. | 2017 | Details |
| A16847 | 28128372 | Food Funct | The hepatoprotective effect of Phyllanthus emblica L. fruit on high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in SD rats. | 2017 | Details |
| A16856 | 28125040 | Molecules | Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. | 2017 | Details |
| A16861 | 28123944 | Mol Metab | Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1. | 2016 | Details |
| A16887 | 28110063 | Int Immunopharmacol | Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation. | 2017 | Details |
| A16888 | 28109892 | Free Radic Biol Med | Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis. | 2017 | Details |
| A16910 | 28098910 | Mol Med Rep | Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. | 2017 | Details |
| A16961 | 28073422 | Zhonghua Gan Zang Bing Za Zhi | [Research advances in the association between deacetylase Sirtuin3 and liver diseases]. | 2016 | Details |
| A16976 | 28067231 | Sci Rep | Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. | 2017 | Details |
| A17008 | 28051796 | Ann Hepatol |  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. | 2017 | Details |
| A17011 | 28051126 | Sci Rep | Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis. | 2017 | Details |
| A17062 | 28012599 | Med Hypotheses | Blood oxidative stress (BLOS) is a secondary host defense system responding normally to anaerobic wound infection and inadvertently to dietary ultra-exogenous sulfide formation (USF). | 2016 | Details |
| A17073 | 28007783 | FASEB J | Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice. | 2016 | Details |
| A17080 | 28002036 | Rom J Intern Med | Serum Levels of Oxidative Stress Markers in Patients with Type 2 Diabetes Mellitus and Non-alcoholic Steatohepatitis. | 2016 | Details |
| A17081 | 28001263 | Rev Assoc Med Bras (1992) | Current management of non-alcoholic fatty liver disease. | 2016 | Details |
| A17082 | 28000843 | Int J Mol Med | Wheat-bran autolytic peptides containing a branched-chain amino acid attenuate non-alcoholic steatohepatitis via the suppression of oxidative stress and the upregulation of AMPK/ACC in high-fat diet-fed mice. | 2016 | Details |
| A17087 | 27998724 | Am J Pathol | Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis. | 2016 | Details |
| A17091 | 27996362 | Toxicol Mech Methods | The effects of di 2-ethyl hexyl phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms in the molecular level. | 2017 | Details |
| A17096 | 27995280 | Arch Toxicol | Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A17111 | 27986466 | Trends Endocrinol Metab | Mitochondrial Adaptation in Nonalcoholic Fatty Liver Disease: Novel Mechanisms and Treatment Strategies. | 2016 | Details |
| A17116 | 27984176 | J Hepatol | PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis. | 2016 | Details |
| A17120 | 27981809 | Mol Nutr Food Res | Chicoric acid attenuate a nonalcoholic steatohepatitis by inhibiting key regulators of lipid metabolism, fibrosis, oxidation, and inflammation in mice with methionine and choline deficiency. | 2017 | Details |
| A17123 | 27980597 | Nutr Metab (Lond) | Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis. | 2016 | Details |
| A17136 | 27973423 | Nutrients | Regressive Effect of Myricetin on Hepatic Steatosis in Mice Fed a High-Fat Diet. | 2016 | Details |
| A17143 | 27959936 | PLoS One | A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. | 2016 | Details |
| A17144 | 27959408 | Mol Med Rep | Involvement of xanthine oxidase and paraoxonase 1 in the process of oxidative stress in nonalcoholic fatty liver disease. | 2016 | Details |
| A17146 | 27957651 | Metab Brain Dis | Carnosic acid protects non-alcoholic fatty liver-induced dopaminergic neuron injury in rats. | 2016 | Details |
| A17149 | 27957239 | Oxid Med Cell Longev | Oxidative Stress and Liver Cancer: Etiology and Therapeutic Targets. | 2016 | Details |
| A17159 | 27941355 | Curr Opin Infect Dis | Managing nonalcoholic fatty liver disease in patients living with HIV. | 2017 | Details |
| A17170 | 27935258 | Mol Nutr Food Res | Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation. | 2017 | Details |
| A17172 | 27935134 | Cell Biochem Funct | Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis. | 2016 | Details |
| A17189 | 27920819 | Res Pharm Sci | Co-administration of metformin and N-acetylcysteine with dietary control improves the biochemical and histological manifestations in rats with non-alcoholic fatty liver. | 2016 | Details |
| A17199 | 27917437 | Cell Tissue Res | Nicotine plus a high-fat diet triggers cardiomyocyte apoptosis. | 2016 | Details |
| A17210 | 27913210 | Free Radic Biol Med | TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. | 2016 | Details |
| A17219 | 27907824 | J Nutr Biochem | Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets. | 2016 | Details |
| A17241 | 27893783 | PLoS One | Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice. | 2016 | Details |
| A17255 | 27889327 | Mol Aspects Med | Epigenetics in non-alcoholic fatty liver disease. | 2016 | Details |
| A17264 | 27880981 | Hepatology | A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice. | 2017 | Details |
| A17278 | 27866836 | Cell Metab | Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. | 2016 | Details |
| A17279 | 27866076 | J Nutr Biochem | Antioxidant properties of tea blunt ROS-dependent lipogenesis: beneficial effect on hepatic steatosis in a high fat-high sucrose diet NAFLD obese rat model. | 2016 | Details |
| A17286 | 27862769 | Cancer Sci | NS5ABP37 inhibits liver cancer by impeding lipogenesis and cholesterogenesis. | 2017 | Details |
| A17297 | 27859493 | Clin Exp Pharmacol Physiol | Connexin32 deficiency is associated with liver injury, inflammation and oxidative stress in experimental non-alcoholic steatohepatitis. | 2017 | Details |
| A17309 | 27855316 | J Nutr Biochem | A high-fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult. | 2016 | Details |
| A17321 | 27847552 | Oxid Med Cell Longev | Schisandrin B: A Double-Edged Sword in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A17326 | 27843095 | EBioMedicine | Branched Chain Amino Acids Cause Liver Injury in Obese/Diabetic Mice by Promoting Adipocyte Lipolysis and Inhibiting Hepatic Autophagy. | 2016 | Details |
| A17335 | 27836788 | Chem Biol Interact | Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage. | 2016 | Details |
| A17340 | 27834813 | Biology (Basel) | The Potential of Non-Provitamin A Carotenoids for the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17368 | 27822476 | Biomed Res Int | Pathogenesis of Nonalcoholic Steatohepatitis: Interactions between Liver Parenchymal and Nonparenchymal Cells. | 2016 | Details |
| A17401 | 27803497 | Med Sci Monit | Clinical Study of Serum Homocysteine and Non-Alcoholic Fatty Liver Disease in Euglycemic Patients. | 2016 | Details |
| A17419 | 27794174 | Mol Nutr Food Res | Polyphenol-rich virgin olive oil reduces insulin resistance and liver inflammation and improves mitochondrial dysfunction in high-fat diet fed rats. | 2016 | Details |
| A17423 | 27788733 | Zhonghua Gan Zang Bing Za Zhi | [Fine particulate matter and nonalcoholic fatty liver disease]. | 2016 | Details |