Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09557 | 31695251 | J Clin Exp Hepatol | Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A09569 | 31692226 | Diabetes Obes Metab | Exenatide and dapagliflozin combination improves markers of liver steatosis and fibrosis in patients with type 2 diabetes. | 2019 | Details |
| A09574 | 31690932 | J Clin Endocrinol Metab | Targeted Analysis of Three Hormonal Systems Identifies Molecules Associated with the Presence and Severity of NAFLD. | 2020 | Details |
| A09575 | 31689910 | Nutrients | The Role of Probiotics in Nonalcoholic Fatty Liver Disease: A New Insight into Therapeutic Strategies. | 2019 | Details |
| A09581 | 31688305 | Eur J Gastroenterol Hepatol | Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09582 | 31687367 | Can J Gastroenterol Hepatol | The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. | 2019 | Details |
| A09585 | 31686320 | Sci China Life Sci | Regulation of glucose and lipid metabolism in health and disease. | 2019 | Details |
| A09587 | 31685793 | Nutr Diabetes | Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements. | 2019 | Details |
| A09588 | 31685037 | Br J Nutr | Whole-grain consumption and its effects on hepatic steatosis and liver enzymes in patients with non-alcoholic fatty liver disease: a randomised controlled clinical trial. | 2019 | Details |
| A09600 | 31679693 | Biochem Biophys Res Commun | Identification of isotschimgine as a novel farnesoid X receptor agonist with potency for the treatment of obesity in mice. | 2019 | Details |
| A09604 | 31677889 | Nutr Metab Cardiovasc Dis | Insulin resistance, but not insulin response, during oral glucose tolerance test (OGTT) is associated to worse histological outcome in obese NAFLD. | 2019 | Details |
| A09612 | 31675274 | Metab Syndr Relat Disord | Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection. | 2019 | Details |
| A09620 | 31672448 | Metabolism | Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box! | 2019 | Details |
| A09622 | 31671785 | Nutrients | mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance. | 2019 | Details |
| A09628 | 31669275 | Int J Biol Macromol | Codonopsis lanceolata polysaccharide CLPS alleviates high fat/high sucrose diet-induced insulin resistance via anti-oxidative stress. | 2019 | Details |
| A09635 | 31668088 | Int J Environ Health Res | Evaluation of sucrose-enriched diet consumption in the development of risk factors associated to type 2 diabetes, atherosclerosis and non-alcoholic fatty liver disease in a murine model. | 2019 | Details |
| A09648 | 31659239 | Acta Pharmacol Sin | Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway. | 2019 | Details |
| A09649 | 31659105 | Cancer Genomics Proteomics | Synergism of Adipocytokine Profile and ADIPOQ/TNF-α Polymorphisms in NAFLD-associated MetS Predict Colorectal Liver Metastases Outgrowth. | 2020 | Details |
| A09661 | 31655133 | J Hepatol | β-Klotho gene variation is associated with liver damage in children with NAFLD. | 2019 | Details |
| A09668 | 31652837 | Cancers (Basel) | Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer. | 2019 | Details |
| A09686 | 31648561 | FASEB J | KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-κB-FGF21 or SREBP1c-FGF21 pathway. | 2019 | Details |
| A09698 | 31641351 | Int J Endocrinol | RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09709 | 31637670 | Obes Surg | What Is the Role of the New Index Relative Fat Mass (RFM) in the Assessment of Nonalcoholic Fatty Liver Disease (NAFLD)? | 2020 | Details |
| A09710 | 31637346 | J Endocr Soc | Nonalcoholic Fatty Liver Disease in Nonobese Subjects of African Origin Has Atypical Metabolic Characteristics. | 2019 | Details |
| A09711 | 31637181 | J Transl Int Med | Effect of Weight Reduction on Histological Activity and Fibrosis of Lean Nonalcoholic Steatohepatitis Patient. | 2019 | Details |
| A09722 | 31634046 | J Med Food | Oral Administration of Hoodia parviflora Alleviates Insulin Resistance and Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09723 | 31633724 | Arq Gastroenterol | A STUDY OF METABOLIC PARAMETERS IN NON DIABETIC PATIENTS WITH NON ALCOHOLIC FATTY LIVER DISEASE - IMPORTANCE OF DYSLIPIDEMIA. | 2019 | Details |
| A09734 | 31632109 | Diabetes Metab Syndr Obes | Plant-derived oleanolic acid ameliorates markers associated with non-alcoholic fatty liver disease in a diet-induced pre-diabetes rat model. | 2019 | Details |
| A09738 | 31630897 | Trends Endocrinol Metab | NAFLD and Atherosclerosis: Two Sides of the Same Dysmetabolic Coin? | 2019 | Details |
| A09742 | 31629472 | Biochem Biophys Res Commun | MC4R deficiency in pigs results in hyperphagia and ultimately hepatic steatosis without high-fat diet. | 2019 | Details |
| A09744 | 31628998 | Clin Gastroenterol Hepatol | Decreased Physical Working Capacity in Adolescents With Nonalcoholic Fatty Liver Disease Associates With Reduced Iron Availability. | 2019 | Details |
| A09751 | 31625959 | Eur J Gastroenterol Hepatol | Homeostatic model assessment of insulin resistance closely related to lobular inflammation in nonalcoholic fatty liver disease. | 2020 | Details |
| A09762 | 31620647 | Transl Gastroenterol Hepatol | Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations. | 2019 | Details |
| A09763 | 31620616 | Yeungnam Univ J Med | Pharmacologic therapy for nonalcoholic steatohepatitis focusing on pathophysiology. | 2019 | Details |
| A09771 | 31616384 | Front Endocrinol (Lausanne) | Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09798 | 31606352 | Ann Hepatol | Chronic kidney disease in patients with non-alcoholic fatty liver disease: What the Hepatologist should know? | 2019 | Details |
| A09800 | 31604965 | Sci Rep | Depletion of CD40 on CD11c+ cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. | 2019 | Details |
| A09803 | 31604171 | Atherosclerosis | Visceral adipose tissue volume is associated with premature atherosclerosis in early type 2 diabetes mellitus independent of traditional risk factors. | 2019 | Details |
| A09804 | 31604107 | Life Sci | Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome. | 2019 | Details |
| A09805 | 31604029 | Am J Physiol Gastrointest Liver Physiol | Intermittent restraint-induced sympathetic activation attenuates hepatic steatosis and inflammation in a high-fat diet-fed mouse model. | 2019 | Details |
| A09814 | 31600750 | Digestion | Rodent Models of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09815 | 31599882 | Rev Invest Clin | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1, NON-ALCOHOLIC FATTY LIVER DISEASE, AND ITS RELATIONSHIP WITH FRUCTOSE CONSUMPTION IN CHILDREN WITH OBESITY. | 2019 | Details |
| A09839 | 31594102 | Zhonghua Gan Zang Bing Za Zhi | [Research advances in the relationship between nonalcoholic fatty fiver disease and sarcopenia]. | 2019 | Details |
| A09848 | 31592078 | Hepatol Commun | Development of a Plasma Screening Panel for Pediatric Nonalcoholic Fatty Liver Disease Using Metabolomics. | 2019 | Details |
| A09855 | 31590127 | Biomed Pharmacother | Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage. | 2019 | Details |
| A09857 | 31589891 | J Hepatol | Change in hepatic fat content measured by MRI does not predict treatment-induced histological improvement of steatohepatitis. | 2019 | Details |
| A09860 | 31588816 | Arch Physiol Biochem | The association between retinol-binding protein 4 and prediabetes in obese patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A09873 | 31581129 | Endocr Connect | Hyperinsulinaemia: does it tip the balance toward intrahepatic fat accumulation? | 2019 | Details |
| A09876 | 31578240 | Sci Transl Med | Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates. | 2019 | Details |
| A09888 | 31574193 | Mol Nutr Food Res | Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation. | 2019 | Details |
| A09892 | 31572482 | Arch Med Sci | Effect of Lactobacillus paracasei N1115 and fructooligosaccharides in nonalcoholic fatty liver disease. | 2019 | Details |
| A09907 | 31566148 | Public Health Nutr | Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and elderly adults. | 2019 | Details |
| A09908 | 31565874 | Endocrinol Metab (Seoul) | Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective. | 2019 | Details |
| A09923 | 31558861 | World J Gastroenterol | Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways. | 2019 | Details |
| A09933 | 31554932 | Nat Rev Endocrinol | The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state. | 2019 | Details |
| A09936 | 31554294 | Medicina (Kaunas) | Relationship between Muscle Mass/Strength and Hepatic Fat Content in Post-Menopausal Women. | 2019 | Details |
| A09944 | 31551213 | Pak J Pharm Sci | Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients. | 2019 | Details |
| A09952 | 31545283 | Biomed Pharmacother | Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression. | 2019 | Details |
| A09967 | 31541591 | J Pineal Res | Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner. | 2019 | Details |
| A09969 | 31540903 | Diabetes Care | Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial. | 2019 | Details |
| A09978 | 31538291 | Endocrine | Nonalcoholic fatty liver disease in women with polycystic ovary syndrome. | 2019 | Details |
| A09983 | 31536725 | Eur J Pharmacol | Farnesoid X nuclear receptor agonists for the treatment of nonalcoholic steatohepatitis. | 2019 | Details |
| A09984 | 31536600 | PLoS One | Asprosin response in hypoglycemia is not related to hypoglycemia unawareness but rather to insulin resistance in type 1 diabetes. | 2019 | Details |
| A09986 | 31535735 | Nutr Clin Pract | Nonalcoholic Fatty Pancreas Disease. | 2019 | Details |
| A09987 | 31535207 | J Gastroenterol | Association between body size-metabolic phenotype and nonalcoholic steatohepatitis and significant fibrosis. | 2019 | Details |
| A09990 | 31534089 | Intern Med | Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09999 | 31530849 | Sci Rep | Controlling Obesity and Metabolic Diseases by Hydrodynamic Delivery of a Fusion Gene of Exendin-4 and α1 Antitrypsin. | 2019 | Details |
| A10002 | 31529722 | Hepatology | Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice. | 2020 | Details |
| A10003 | 31529495 | Hepatology | Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3. | 2020 | Details |
| A10006 | 31528245 | World J Hepatol | Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. | 2019 | Details |
| A10007 | 31527322 | J Atheroscler Thromb | Association of Fetuin-B with Subclinical Atherosclerosis in Obese Chinese Adults. | 2019 | Details |
| A10009 | 31526528 | J Pediatr | The Contribution of the Adipose Tissue-Liver Axis in Pediatric Patients with Nonalcoholic Fatty Liver Disease after Laparoscopic Sleeve Gastrectomy. | 2019 | Details |
| A10014 | 31523999 | Expert Opin Investig Drugs | Elafibranor: a potential drug for the treatment of nonalcoholic steatohepatitis (NASH). | 2019 | Details |
| A10023 | 31521175 | Lipids Health Dis | Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities. | 2019 | Details |
| A10039 | 31517324 | J Gastrointestin Liver Dis | Effects of Dietary Intervention on Gut Microbiota and Metabolic-Nutritional Profile of Outpatients with Non-Alcoholic Steatohepatitis: a Randomized Clinical Trial. | 2019 | Details |
| A10041 | 31516268 | J Clin Exp Hepatol | Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges. | 2019 | Details |
| A10042 | 31516267 | J Clin Exp Hepatol | Screening of Cardiovascular Disease in Nonalcoholic Fatty Liver Disease: Whom and How? | 2019 | Details |
| A10054 | 31510077 | Nutrients | A Low Iron Diet Protects from Steatohepatitis in a Mouse Model. | 2019 | Details |
| A10056 | 31506976 | Hepatology | Vitamin D Receptor Activation in Liver Macrophages Ameliorates Hepatic Inflammation, Steatosis, and Insulin Resistance in Mice. | 2020 | Details |
| A10074 | 31500354 | Cells | Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. | 2019 | Details |
| A10076 | 31497874 | Br J Pharmacol | Delayed intervention with a novel SGLT2 inhibitor NGI001 suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice. | 2019 | Details |
| A10078 | 31497742 | Hepatol Commun | Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance. | 2019 | Details |
| A10082 | 31496048 | Physiol Rep | Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. | 2019 | Details |
| A10087 | 31493247 | Hormones (Athens) | Selenium and selenoprotein P in nonalcoholic fatty liver disease. | 2019 | Details |
| A10094 | 31488477 | BMJ Open | Association between nut intake and non-alcoholic fatty liver disease risk: a retrospective case-control study in a sample of Chinese Han adults. | 2019 | Details |
| A10098 | 31485221 | Int J Endocrinol | Compound C Protects Mice from HFD-Induced Obesity and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10099 | 31484323 | Nutrients | Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. | 2019 | Details |
| A10105 | 31482785 | Am J Trop Med Hyg | Opisthorchis viverrini Infection Augments the Severity of Nonalcoholic Fatty Liver Disease in High-Fat/High-Fructose Diet-Fed Hamsters. | 2019 | Details |
| A10106 | 31482741 | Arch Physiol Biochem | Low level of adiponectin predicts the development of Nonalcoholic fatty liver disease: is it irrespective to visceral adiposity index, visceral adipose tissue thickness and other obesity indices? | 2019 | Details |
| A10116 | 31477078 | BMC Endocr Disord | Cholecystectomy versus central obesity or insulin resistance in relation to the risk of nonalcoholic fatty liver disease: the third US National Health and Nutrition Examination Survey. | 2019 | Details |
| A10125 | 31474632 | Yakugaku Zasshi | [Role of Angiogenesis and Chronic Inflammation in Fat Hypertrophy in NASH Pathology]. | 2019 | Details |
| A10134 | 31472955 | Biochem Biophys Res Commun | Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice. | 2019 | Details |
| A10139 | 31470786 | Curr Pharm Des | A Mitochondrial Approach to Cardiovascular Risk and Disease. | 2019 | Details |
| A10143 | 31470414 | Endocr Connect | Insulin resistance associates with hepatic lobular inflammation in subjects with obesity. | 2019 | Details |
| A10149 | 31469122 | Pol Arch Intern Med | Serum pentraxin 3 concentration in patients with type 2 diabetes and nonalcoholic fatty liver disease. | 2019 | Details |
| A10150 | 31467918 | Biomed Res Int | Abdominal Obesity as a Predictive Factor of Nonalcoholic Fatty Liver Disease Assessed by Ultrasonography and Transient Elastography in Polycystic Ovary Syndrome and Healthy Women. | 2019 | Details |
| A10167 | 31460789 | Am J Physiol Gastrointest Liver Physiol | Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis. | 2019 | Details |
| A10168 | 31460584 | Arq Gastroenterol | N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL. | 2019 | Details |
| A10178 | 31449538 | PLoS One | Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight. | 2019 | Details |
| A10201 | 31436362 | Liver Int | Plasma N-terminal propeptide of type III procollagen accurately predicts liver fibrosis severity in children with non-alcoholic fatty liver disease. | 2019 | Details |