Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11157 | 31018719 | Expert Rev Gastroenterol Hepatol | Noninvasive monitoring of hepatic steatosis: controlled attenuation parameter and magnetic resonance imaging-proton density fat fraction in patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A11159 | 31018538 | Int J Mol Sci | Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model. | 2019 | Details |
| A11164 | 31013988 | Nutrients | A Slow-Digesting Carbohydrate Diet during Rat Pregnancy Protects Offspring from Non-Alcoholic Fatty Liver Disease Risk through the Modulation of the Carbohydrate-Response Element and Sterol Regulatory Element Binding Proteins. | 2019 | Details |
| A11191 | 31004931 | Environ Toxicol Pharmacol | Mono-2-ethylhexyl phthalate induces the expression of genes involved in fatty acid synthesis in HepG2 cells. | 2019 | Details |
| A11192 | 31004828 | Cell Mol Gastroenterol Hepatol | Metabolic Targets in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11201 | 31002661 | PLoS Comput Biol | Investigating the deregulation of metabolic tasks via Minimum Network Enrichment Analysis (MiNEA) as applied to nonalcoholic fatty liver disease using mouse and human omics data. | 2019 | Details |
| A11210 | 30995792 | Int J Mol Sci | Glucagon-Induced Acetylation of Energy-Sensing Factors in Control of Hepatic Metabolism. | 2019 | Details |
| A11223 | 30987167 | Int J Mol Sci | Ameliorative Effect of Spinach on Non-Alcoholic Fatty Liver Disease Induced in Rats by a High-Fat Diet. | 2019 | Details |
| A11231 | 30983568 | Elife | Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis. | 2019 | Details |
| A11233 | 30982168 | Obes Surg | Vertical Sleeve Gastrectomy Attenuates the Progression of Non-Alcoholic Steatohepatitis in Mice on a High-Fat High-Cholesterol Diet. | 2019 | Details |
| A11245 | 30975991 | Nat Commun | Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα. | 2019 | Details |
| A11247 | 30974975 | Hum Exp Toxicol | Aromatic aldehyde compound cuminaldehyde protects nonalcoholic fatty liver disease in rats feeding high fat diet. | 2019 | Details |
| A11251 | 30973961 | FEBS Lett | Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia-induced hepatic steatosis in vitro and in vivo. | 2019 | Details |
| A11259 | 30971408 | Dis Model Mech | Beneficial effects of exercise on gut microbiota functionality and barrier integrity, and gut-liver crosstalk in an in vivo model of early obesity and non-alcoholic fatty liver disease. | 2019 | Details |
| A11282 | 30959108 | J Struct Biol | MBOAT7 is anchored to endomembranes by six transmembrane domains. | 2019 | Details |
| A11286 | 30957185 | Mol Med Rep | Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OA‑treated HepG2 cells. | 2019 | Details |
| A11297 | 30950217 | J Cell Mol Med | Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways. | 2019 | Details |
| A11302 | 30948912 | World J Gastroenterol | Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway. | 2019 | Details |
| A11305 | 30947410 | Math Biosci Eng | Analysis of compartments-in-series models of liver metabolism as partial differential equations: the effect of dispersion and number of compartments. | 2019 | Details |
| A11308 | 30945501 | Zhen Ci Yan Jiu | [Acupuncture improves hepatic lipid metabolism by suppressing oxidative stress in obese nonalcoholic fatty liver disease rats]. | 2019 | Details |
| A11313 | 30943218 | PLoS One | Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice. | 2019 | Details |
| A11314 | 30942685 | Proc Nutr Soc | The influence of dietary fatty acids on liver fat content and metabolism. | 2019 | Details |
| A11321 | 30939745 | Int J Mol Sci | 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. | 2019 | Details |
| A11322 | 30938723 | Food Funct | Spinach consumption ameliorates the gut microbiota and dislipaemia in rats with diet-induced non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A11323 | 30937936 | J Cell Physiol | Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes. | 2019 | Details |
| A11332 | 30935037 | Nutrients | Melatonin Improves Fatty Liver Syndrome by Inhibiting the Lipogenesis Pathway in Hamsters with High-Fat Diet-Induced Hyperlipidemia. | 2019 | Details |
| A11349 | 34485777 | Curr Opin Toxicol | Polychlorinated Biphenyls and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11353 | 30926171 | Biochem Biophys Res Commun | PEDF promotes nuclear degradation of ATGL through COP1. | 2019 | Details |
| A11363 | 30921653 | Adv Med Sci | Can hepatokines be regarded as novel non-invasive serum biomarkers of intrahepatic lipid content in obese children? | 2019 | Details |
| A11364 | 30921449 | PLoS One | Combined effects of ambient particulate matter exposure and a high-fat diet on oxidative stress and steatohepatitis in mice. | 2019 | Details |
| A11368 | 30920415 | Am J Gastroenterol | Angiotensin II Type 1 Receptor rs5186 Gene Variant Predicts Incident NAFLD and Associated Hypertension: Role of Dietary Fat-Induced Pro-Inflammatory Cell Activation. | 2019 | Details |
| A11374 | 30919335 | Adv Exp Med Biol | miRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A11381 | 30918066 | J Lipid Res | PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells. | 2019 | Details |
| A11387 | 30916873 | Liver Int | Fibroblast growth factor 21 is independently associated with severe hepatic steatosis in non-obese HIV-infected patients. | 2019 | Details |
| A11400 | 30912307 | Physiol Rep | The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats. | 2019 | Details |
| A11403 | 30909521 | Cells | A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver. | 2019 | Details |
| A11412 | 30905785 | Biochim Biophys Acta Mol Basis Dis | Intestinal vitamin D receptor modulates lipid metabolism, adipose tissue inflammation and liver steatosis in obese mice. | 2019 | Details |
| A11423 | 30901029 | Endocr Rev | Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule. | 2019 | Details |
| A11442 | 30893090 | Curr Opin Clin Nutr Metab Care | Sarcopenic obesity in fatty liver. | 2019 | Details |
| A11446 | 30891617 | J Mol Med (Berl) | Innate immune regulatory networks in hepatic lipid metabolism. | 2019 | Details |
| A11447 | 30891575 | Animal Model Exp Med | Obese zebrafish: A small fish for a major human health condition. | 2018 | Details |
| A11451 | 30889343 | Rev Med Inst Mex Seguro Soc | Nonalcoholic hepatic steatosis: a silent disease | 2019 | Details |
| A11461 | 30887659 | Int J Exp Pathol | Vitronectin deficiency attenuates hepatic fibrosis in a non-alcoholic steatohepatitis-induced mouse model. | 2019 | Details |
| A11473 | 30881473 | Evid Based Complement Alternat Med | Jwa Kum Whan Attenuates Nonalcoholic Fatty Liver Disease by Modulating Glucose Metabolism and the Insulin Signaling Pathway. | 2019 | Details |
| A11477 | 30879920 | EBioMedicine | Arid1a regulates insulin sensitivity and lipid metabolism. | 2019 | Details |
| A11497 | 30871035 | Nutrients | Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells. | 2019 | Details |
| A11504 | 30868489 | Curr Med Sci | Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC Pathway. | 2019 | Details |
| A11516 | 30862046 | Int J Mol Sci | Metabolomics Characterizes the Effects and Mechanisms of Quercetin in Nonalcoholic Fatty Liver Disease Development. | 2019 | Details |
| A11528 | 30856468 | J Nutr Biochem | Tissue-dependent effects of cis-9,trans-11- and trans-10,cis-12-CLA isomers on glucose and lipid metabolism in adult male mice. | 2019 | Details |
| A11538 | 30851741 | Lipids Health Dis | TRIB1 rs17321515 and rs2954029 gene polymorphisms increase the risk of non-alcoholic fatty liver disease in Chinese Han population. | 2019 | Details |
| A11539 | 30851372 | J Ethnopharmacol | Protective effect and mechanism of Qiwei Tiexie capsule on 3T3-L1 adipocytes cells and rats with nonalcoholic fatty liver disease by regulating LXRα, PPARγ, and NF-κB-iNOS-NO signaling pathways. | 2019 | Details |
| A11544 | 30850262 | Trends Endocrinol Metab | Calcium Signaling As a Therapeutic Target for Liver Steatosis. | 2019 | Details |
| A11548 | 30848932 | FASEB J | Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3. | 2019 | Details |
| A11556 | 30841536 | Int J Mol Sci | mTOR is a Key Protein Involved in the Metabolic Effects of Simple Sugars. | 2019 | Details |
| A11563 | 30838350 | Acta Myol | Prevalence of metabolic syndrome and non-alcoholic fatty liver disease in a cohort of italian patients with spinal-bulbar muscular atrophy. | 2018 | Details |
| A11572 | 30834336 | JGH Open | Differences in the genetic backgrounds of patients with alcoholic liver disease and non-alcoholic fatty liver disease. | 2018 | Details |
| A11576 | 30833154 | Endocrinol Diabetes Nutr (Engl Ed) | Inflammatory stress and altered angiogenesis evoked by very high-fat diets in mouse liver. | 2019 | Details |
| A11580 | 30832407 | Nutrients | Dietary Polyphenols Protect Against Oleic Acid-Induced Steatosis in an in Vitro Model of NAFLD by Modulating Lipid Metabolism and Improving Mitochondrial Function. | 2019 | Details |
| A11600 | 30824369 | Clin Res Hepatol Gastroenterol | Meta-analysis of the association between MBOAT7 rs641738, TM6SF2 rs58542926 and nonalcoholic fatty liver disease susceptibility. | 2019 | Details |
| A11604 | 30823334 | Environ Pollut | Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines. | 2019 | Details |
| A11609 | 30820969 | Hepatology | Dual Specificity Phosphatase 12 Regulates Hepatic Lipid Metabolism Through Inhibition of the Lipogenesis and Apoptosis Signal-Regulating Kinase 1 Pathways. | 2019 | Details |
| A11613 | 30819364 | J Am Coll Cardiol | Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review. | 2019 | Details |
| A11623 | 30814508 | Nat Commun | Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism. | 2019 | Details |
| A11625 | 30813654 | Nutrients | Lonicera caerulea Extract Attenuates Non-Alcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Hepatocytes and in High Fat Diet-Fed Mice. | 2019 | Details |
| A11631 | 30811073 | Hepatol Res | Hepatic gene expression in mouse models of non-alcoholic fatty liver disease after acute exercise. | 2019 | Details |
| A11656 | 30802724 | Nutr Res | Schizandrin A supplementation improves nonalcoholic fatty liver disease in mice fed a high-fat and high-cholesterol diet. | 2019 | Details |
| A11664 | 30798028 | Environ Pollut | MicroRNA-26a-CD36 signaling pathway: Pivotal role in lipid accumulation in hepatocytes induced by PM2.5 liposoluble extracts. | 2019 | Details |
| A11666 | 30797009 | Int J Biol Macromol | Mussel polysaccharide α-D-glucan (MP-A) protects against non-alcoholic fatty liver disease via maintaining the homeostasis of gut microbiota and regulating related gut-liver axis signaling pathways. | 2019 | Details |
| A11676 | 30793717 | Food Funct | Activated TNF-α/RIPK3 signaling is involved in prolonged high fat diet-stimulated hepatic inflammation and lipid accumulation: inhibition by dietary fisetin intervention. | 2019 | Details |
| A11721 | 30777418 | Rev Med Inst Mex Seguro Soc | Molecular alterations induced by fructose and its impact on metabolic diseases | 2019 | Details |
| A11724 | 30776032 | Food Funct | Myricetin alleviated hepatic steatosis by acting on microRNA-146b/thyroid hormone receptor b pathway in high-fat diet fed C57BL/6J mice. | 2019 | Details |
| A11739 | 30770098 | Biochem Biophys Res Commun | Genetic deletion of β2 adrenergic receptors exacerbates hepatocellular lipid accumulation in high-fat diet mice. | 2019 | Details |
| A11743 | 30769284 | Redox Biol | Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis. | 2019 | Details |
| A11748 | 30767421 | Diabetes Metab Res Rev | The association between pancreas steatosis and metabolic syndrome: A systematic review and meta-analysis. | 2019 | Details |
| A11749 | 30766961 | Hepatol Commun | Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity. | 2018 | Details |
| A11750 | 30766955 | Hepatol Commun | Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine. | 2019 | Details |
| A11756 | 30765737 | Sci Rep | Nutritional and lipidomics biomarkers of docosahexaenoic acid-based multivitamin therapy in pediatric NASH. | 2019 | Details |
| A11768 | 30759275 | Mol Genet Genomics | Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model. | 2019 | Details |
| A11777 | 30753863 | Eur J Pharmacol | Acetaminophen aggravates fat accumulation in NAFLD by inhibiting autophagy via the AMPK/mTOR pathway. | 2019 | Details |
| A11778 | 30748020 | Hepatology | Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome Proliferator-Activated Receptor γ in Mice. | 2019 | Details |
| A11779 | 30747091 | Curr Mol Pharmacol | Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone. | 2019 | Details |
| A11786 | 30745416 | J Pharmacol Exp Ther | RLA8-A New and Highly Effective Quadruple PPAR-α/γ/δ and GPR40 Agonist to Reverse Nonalcoholic Steatohepatitis and Fibrosis. | 2019 | Details |
| A11795 | 30738135 | Food Chem Toxicol | Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte. | 2019 | Details |
| A11801 | 30735525 | PLoS One | Epidermal growth factor receptor inhibition attenuates non-alcoholic fatty liver disease in diet-induced obese mice. | 2019 | Details |
| A11814 | 30724128 | Physiology (Bethesda) | Impact of Lipotoxicity on Tissue "Cross Talk" and Metabolic Regulation. | 2019 | Details |
| A11816 | 30723896 | Lipids | Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways. | 2019 | Details |
| A11821 | 30720827 | Food Funct | Monascus yellow, red and orange pigments from red yeast rice ameliorate lipid metabolic disorders and gut microbiota dysbiosis in Wistar rats fed on a high-fat diet. | 2019 | Details |
| A11826 | 30719457 | J Immunol Res | The Crosstalk between Fat Homeostasis and Liver Regional Immunity in NAFLD. | 2019 | Details |
| A11828 | 30718741 | Sci Rep | Dietary Niacin Intake Predicts the Decrease of Liver Fat Content During a Lifestyle Intervention. | 2019 | Details |
| A11836 | 30713255 | Biol Pharm Bull | Preventive Effect of Citrus aurantium Peel Extract on High-Fat Diet-Induced Non-alcoholic Fatty Liver in Mice. | 2019 | Details |
| A11839 | 30711707 | Toxicology | The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice. | 2019 | Details |
| A11840 | 30711569 | Metabolism | LncRNA MEG3 functions as a ceRNA in regulating hepatic lipogenesis by competitively binding to miR-21 with LRP6. | 2019 | Details |
| A11865 | 30704899 | Mol Cell | Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism. | 2019 | Details |
| A11866 | 30703849 | Hepatology | F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
| A11874 | 30701776 | Ter Arkh | Intrahepatic cholestasis in nonalcoholic fatty liver disease. | 2018 | Details |
| A11877 | 30700851 | Lab Invest | Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis. | 2019 | Details |
| A11883 | 30697640 | Biochem Genet | Down-Regulation of SIRT1 Expression by mir-23b Contributes to Lipid Accumulation in HepG2 Cells. | 2019 | Details |
| A11885 | 30695042 | PLoS One | Fc gamma RIIb expression levels in human liver sinusoidal endothelial cells during progression of non-alcoholic fatty liver disease. | 2019 | Details |
| A11890 | 30692925 | Front Pharmacol | Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues. | 2019 | Details |
| A11926 | 30680004 | Exp Ther Med | Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPARα and SREBP1. | 2018 | Details |