Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
PPAR2265 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A26560 | 20204774 | Adv Exp Med Biol | Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, improves hepatic microcirculatory patency and oxygen availability in a high-fat-diet-induced fatty liver in mice. | 2010 | Details |
| A26603 | 20111022 | Obesity (Silver Spring) | Effect of dietary monosodium glutamate on HFCS-induced hepatic steatosis: expression profiles in the liver and visceral fat. | 2010 | Details |
| A26623 | 20079722 | Chem Biol Interact | Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. | 2010 | Details |
| A26637 | 20043126 | Int J Mol Med | Long-term feeding of a synthetic diet rich in disaccharides induces hepatic fibrosis in nonalcoholic fatty liver disease in Zucker rats. | 2010 | Details |
| A26650 | 21442055 | Hepatol Int | Peroxisome proliferators-activated receptor γ2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients. | 2010 | Details |
| A26654 | 20040336 | Int J Clin Pharmacol Ther | Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPARalpha-MDR3 pathway. | 2010 | Details |
| A26659 | 20033348 | Obes Surg | SIRT1 transcription is decreased in visceral adipose tissue of morbidly obese patients with severe hepatic steatosis. | 2009 | Details |
| A26661 | 20030578 | Scand J Gastroenterol | Liver transplantation of patients with cryptogenic cirrhosis: clinical characteristics and outcome. | 2010 | Details |
| A26689 | 19948145 | Curr Biol | An emerging role of mTOR in lipid biosynthesis. | 2009 | Details |
| A26699 | 19936233 | PLoS One | IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis. | 2009 | Details |
| A26745 | 19847649 | Dig Dis Sci | The effects of a fat- and sugar-enriched diet and chronic stress on nonalcoholic fatty liver disease in male Wistar rats. | 2009 | Details |
| A26749 | 19839225 | Br J Biomed Sci | Evaluation of some markers of subclinical atherosclerosis in Egyptian young adult males with abdominal obesity. | 2009 | Details |
| A26753 | 19832698 | Clin Sci (Lond) | Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN. | 2009 | Details |
| A26790 | 19780876 | J Gastroenterol Hepatol | Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD. | 2009 | Details |
| A26837 | 19681867 | Br J Pharmacol | Curcumin adds spice to the debate: lipid metabolism in liver disease. | 2009 | Details |
| A26853 | 19650159 | Hepatology | Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis. | 2009 | Details |
| A26878 | 19596472 | J Hepatol | Long-term combination therapy of ezetimibe and acarbose for non-alcoholic fatty liver disease. | 2009 | Details |
| A26904 | 19560226 | J Hepatol | Non-alcoholic fatty liver disease in patients with chronic plaque psoriasis. | 2009 | Details |
| A26908 | 19556219 | Arch Dis Child | A protective effect of breastfeeding on the progression of non-alcoholic fatty liver disease. | 2009 | Details |
| A26915 | 19381122 | Ann Hepatol | Role of nonalcoholic fatty liver disease in hepatocellular carcinoma. | 2009 | Details |
| A26945 | 19491421 | Indian J Med Res | A case-control study on insulin resistance, metabolic co-variates & prediction score in non-alcoholic fatty liver disease. | 2009 | Details |
| A26961 | 19459046 | Dig Dis Sci | Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats. | 2009 | Details |
| A26975 | 19427351 | Toxicology | Protective effect of bicyclol on tetracycline-induced fatty liver in mice. | 2009 | Details |
| A27027 | 19321579 | J Nutr | Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats. | 2009 | Details |
| A27065 | 19230890 | Atherosclerosis | Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model. | 2009 | Details |
| A27123 | 19135440 | Eur J Pharmacol | Comparative therapeutic effects of metformin and vitamin E in a model of non-alcoholic steatohepatitis in the young rat. | 2008 | Details |
| A27139 | 19107341 | J Gastroenterol | Etiology of non-B non-C hepatocellular carcinoma in the eastern district of Tokyo. | 2008 | Details |
| A27149 | 19077512 | Korean J Gastroenterol | [Clinical characteristics of health screen examinees with nonalcoholic fatty liver and normal liver function test]. | 2008 | Details |
| A27168 | 19054139 | Hepatol Res | Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease. | 2008 | Details |
| A27183 | 19025308 | Rev Esp Enferm Dig | [Molecular basis of obesity-related hepatic steatosis]. | 2008 | Details |
| A27199 | 19001666 | J Lipid Res | Effect of dietary monosodium glutamate on trans fat-induced nonalcoholic fatty liver disease. | 2008 | Details |
| A27223 | 18956291 | Semin Liver Dis | Abnormalities of lipid metabolism in nonalcoholic fatty liver disease. | 2008 | Details |
| A27243 | 18853997 | J Gastroenterol Hepatol | A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. | 2008 | Details |
| A27269 | 18791133 | Exp Biol Med (Maywood) | Soy protein isolate reduces hepatosteatosis in yellow Avy/a mice without altering coat color phenotype. | 2008 | Details |
| A27288 | 18752326 | Hepatology | Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice. | 2008 | Details |
| A27352 | 18588668 | BMC Gastroenterol | Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD). | 2008 | Details |
| A27367 | 18532884 | Clin Infect Dis | Nonalcoholic fatty liver disease in HIV-infected patients referred to a metabolic clinic: prevalence, characteristics, and predictors. | 2008 | Details |
| A27374 | 19669305 | Hepatol Int | Comparative redox status in alcoholic liver disease and nonalcoholic fatty liver disease. | 2008 | Details |
| A27390 | 18488193 | Arch Toxicol | Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis. | 2008 | Details |
| A27416 | 18422963 | J Gastroenterol Hepatol | Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2008 | Details |
| A27421 | 18417155 | Life Sci | The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice. | 2008 | Details |
| A27429 | 18336651 | J Gastroenterol Hepatol | Fat paradox of steatohepatitis. | 2008 | Details |
| A27508 | 18240340 | World J Gastroenterol | The blind men 'see' the elephant-the many faces of fatty liver disease. | 2008 | Details |
| A27531 | 18176957 | World J Gastroenterol | Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. | 2008 | Details |
| A27537 | 18171348 | J Gastroenterol Hepatol | PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes. | 2008 | Details |
| A27559 | 18072723 | Mol Pharm | Nonalcoholic fatty liver disease: pathogenesis and potential for nuclear receptors as therapeutic targets. | 2007 | Details |
| A27577 | 17935056 | Diab Vasc Dis Res | The role of fenofibrate in clinical practice. | 2007 | Details |
| A27583 | 17999673 | Liver Int | Effect of peroxisome proliferator-activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people. | 2007 | Details |
| A27588 | 17983472 | BMC Gastroenterol | Prevalence and factors associated with the presence of non alcoholic fatty liver disease in an apparently healthy adult population in primary care units. | 2007 | Details |
| A27603 | 17928738 | J Pharmacol Sci | Life style-related diseases of the digestive system: gene expression in nonalcoholic steatohepatitis patients and treatment strategies. | 2007 | Details |
| A27624 | 17894848 | Am J Gastroenterol | The severity of ultrasonographic findings in nonalcoholic fatty liver disease reflects the metabolic syndrome and visceral fat accumulation. | 2007 | Details |
| A27635 | 17868330 | J Gastroenterol Hepatol | Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation. | 2007 | Details |
| A27640 | 17826687 | Drug Discov Today | Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD). | 2007 | Details |
| A27676 | 17691915 | Curr Drug Discov Technol | Current treatment strategies for non-alcoholic fatty liver disease (NAFLD). | 2007 | Details |
| A27677 | 17690317 | Arterioscler Thromb Vasc Biol | Fatty liver: a novel component of the metabolic syndrome. | 2007 | Details |
| A27684 | 17671740 | Int J Mol Med | Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. | 2007 | Details |
| A27695 | 17654601 | Hepatology | Effects of rosiglitazone on the liver histology and mitochondrial function in ob/ob mice. | 2007 | Details |
| A27702 | 17619535 | Acta Gastroenterol Belg | Pathogenesis of steatohepatitis: insights from the study of animal models. | 2007 | Details |
| A27737 | 17544971 | Clin Liver Dis | Role of radiologic modalities in the management of non-alcoholic steatohepatitis. | 2007 | Details |
| A27761 | 17498218 | J Gastroenterol Hepatol | What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific? | 2007 | Details |
| A27783 | 17461452 | World J Gastroenterol | Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. | 2007 | Details |
| A27787 | 17449148 | Clin Nutr | Update on non-alcoholic fatty liver disease in children. | 2007 | Details |
| A27813 | 17376042 | J Gastroenterol Hepatol | Effects of bariatric surgery on nonalcoholic fatty liver disease: preliminary findings after 2 years. | 2007 | Details |
| A27847 | 17272484 | Clin Chem | Higher concentrations of alanine aminotransferase within the reference interval predict nonalcoholic fatty liver disease. | 2007 | Details |
| A27870 | 17201732 | Clin Exp Pharmacol Physiol | Effects of fenofibrate and xuezhikang on high-fat diet-induced non-alcoholic fatty liver disease. | 2007 | Details |
| A27872 | 17188672 | Chem Biol Interact | A human hepatocellular in vitro model to investigate steatosis. | 2006 | Details |
| A27889 | 17105592 | Liver Int | Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease. | 2006 | Details |
| A27893 | 17073635 | Curr Med Chem | Current pharmacological treatment of nonalcoholic fatty liver. | 2006 | Details |
| A27908 | 17048997 | Rev Esp Enferm Dig | Hepatitis C and insulin resistance: steatosis, fibrosis and non-response. | 2006 | Details |
| A27917 | 17029217 | J Pathol | Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice. | 2006 | Details |
| A27937 | 16949573 | Exp Mol Pathol | Transcriptional networks in a rat model for nonalcoholic fatty liver disease: a microarray analysis. | 2006 | Details |
| A27996 | 16768120 | Nihon Rinsho | [Imaging of NASH]. | 2006 | Details |
| A28003 | 16768103 | Nihon Rinsho | [Current trends of NASH/NAFLD in Asia-Pacific region]. | 2006 | Details |
| A28005 | 16762625 | Gastroenterology | Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. | 2006 | Details |
| A28006 | 16762007 | Liver Int | Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. | 2006 | Details |
| A28025 | 16696395 | J Med Assoc Thai | Serum leptin concentrations in chronic hepatitis. | 2006 | Details |
| A28039 | 16624332 | Life Sci | High-fat emulsion-induced rat model of nonalcoholic steatohepatitis. | 2006 | Details |
| A28046 | 16603729 | Am J Physiol Gastrointest Liver Physiol | Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. | 2006 | Details |
| A28059 | 16540770 | J Clin Gastroenterol | Therapy of NAFLD: insulin sensitizing agents. | 2006 | Details |
| A28071 | 16521351 | Clin Med (Lond) | Non-alcoholic fatty liver disease: current concepts and management strategies. | 2007 | Details |
| A28077 | 16503761 | Expert Opin Investig Drugs | Recent findings concerning thiazolidinediones in the treatment of diabetes. | 2006 | Details |
| A28079 | 16672828 | J Clin Gastroenterol | Therapy of NAFLD: Insulin Sensitizing Agents. | 2006 | Details |
| A28093 | 16452829 | Keio J Med | Fat paradox in liver disease. | 2005 | Details |
| A28095 | 16447287 | Hepatology | Nonalcoholic fatty liver disease: from steatosis to cirrhosis. | 2006 | Details |
| A28096 | 16439872 | AIDS | Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients. | 2006 | Details |
| A28120 | 16374859 | Hepatology | Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. | 2006 | Details |
| A28144 | 16268963 | Aliment Pharmacol Ther | Review article: the treatment of non-alcoholic steatohepatitis with thiazolidinediones. | 2005 | Details |
| A28206 | 16142397 | Int J Mol Med | Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. | 2005 | Details |
| A28215 | 16108839 | Diabet Med | Prevalence of non-alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults. | 2005 | Details |
| A28219 | 16095853 | J Ethnopharmacol | Euonymus alatus prevents the hyperglycemia and hyperlipidemia induced by high-fat diet in ICR mice. | 2005 | Details |
| A28220 | 16093589 | Intern Med | Brachial-ankle pulse wave velocity in Japanese university students. | 2005 | Details |
| A28246 | 15970496 | Front Biosci | Non-alcoholic fatty liver disease (NAFLD) in children. | 2005 | Details |
| A28276 | 15828235 | Nihon Rinsho | [The roles of PPARs in digestive diseases]. | 2005 | Details |
| A28297 | 15754775 | Chang Gung Med J | An adipocentric view of liver fibrosis and cirrhosis. | 2004 | Details |
| A28318 | 15700216 | Z Gastroenterol | The relationship between apoptosis and non-alcoholic fatty liver disease: an evolutionary cornerstone turned pathogenic. | 2005 | Details |
| A28323 | 15683425 | J Gastroenterol Hepatol | Prevalence and etiology of persistently elevated alanine aminotransferase levels in healthy Iranian blood donors. | 2005 | Details |
| A28329 | 15641399 | Acta Clin Belg | Evaluation of abnormal liver-enzyme results in asymptomatic patients. | 2005 | Details |
| A28331 | 15629518 | J Hepatol | The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies. | 2005 | Details |
| A28338 | 15603755 | Mutat Res | Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. | 2005 | Details |
| A28348 | 15554233 | Drug Metab Rev | The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role. | 2004 | Details |