Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08773 | 31988879 | Pediatr Gastroenterol Hepatol Nutr | Factors associated with Advanced Bone Age in Overweight and Obese Children. | 2020 | Details |
| A08777 | 31987259 | Complement Ther Med | The effects of curcumin supplementation on liver function, metabolic profile and body composition in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2019 | Details |
| A08778 | 31987257 | Complement Ther Med | The effects of carnitine supplementation on clinical characteristics of patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2019 | Details |
| A08788 | 31984787 | Am J Physiol Gastrointest Liver Physiol | Vitamin D signaling maintains intestinal innate immunity and gut microbiota: potential intervention for metabolic syndrome and NAFLD. | 2020 | Details |
| A08789 | 31984635 | Neurogastroenterol Motil | Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. | 2020 | Details |
| A08793 | 31982140 | Biochem Biophys Res Commun | Targeting DUSP16/TAK1 signaling alleviates hepatic dyslipidemia and inflammation in high fat diet (HFD)-challenged mice through suppressing JNK MAPK. | 2020 | Details |
| A08822 | 31978277 | Mol Nutr Food Res | Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. | 2020 | Details |
| A08825 | 31975453 | J Gastroenterol Hepatol | Long-term outcomes of non-alcoholic fatty liver disease and the risk factors for mortality and hepatocellular carcinoma in a Japanese population. | 2020 | Details |
| A08833 | 31972071 | Cell Physiol Biochem | Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model. | 2020 | Details |
| A08840 | 31969650 | Sci Rep | Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects. | 2020 | Details |
| A08847 | 31968197 | Endocr Pract | IMPACT OF TYPE 2 DIABETES ON NONALCOHOLIC STEATOHEPATITIS AND ADVANCED FIBROSIS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE. | 2020 | Details |
| A08850 | 31966908 | World J Hepatol | Lumacaftor/ivacaftor therapy is associated with reduced hepatic steatosis in cystic fibrosis patients. | 2019 | Details |
| A08851 | 31965945 | Curr Drug Discov Technol | Alcoholic and Non-Alcoholic Liver Diseases: Promising Molecular Drug Targets and their Clinical Development. | 2021 | Details |
| A08855 | 31965018 | Sci Rep | Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice. | 2020 | Details |
| A08857 | 31963560 | Mar Drugs | Fucus vesiculosus and Ascophyllum nodosum Ameliorate Liver Function by Reducing Diet-Induced Steatosis in Rats. | 2020 | Details |
| A08860 | 31959914 | Cell Death Differ | Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. | 2020 | Details |
| A08864 | 31958476 | Diabetes Res Clin Pract | Fasting C-peptide is a significant indicator of nonalcoholic fatty liver disease in obese children. | 2020 | Details |
| A08867 | 31956961 | Diabetes Ther | Study Protocol for Pleiotropic Effects and Safety of Sodium-Glucose Cotransporter 2 Inhibitor Versus Sulfonylurea in Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08871 | 31955626 | Endocr Res | Therapeutic Effects of SGLT2 Inhibitor Ipragliflozin and Metformin on NASH in Type 2 Diabetic Mice. | 2020 | Details |
| A08872 | 31955491 | Diabetes Metab Res Rev | Efficacy of exenatide and insulin glargine on nonalcoholic fatty liver disease in patients with type 2 diabetes. | 2020 | Details |
| A08883 | 31953228 | Biochim Biophys Acta Mol Cell Biol Lipids | Effects of peptidoglycan on the development of steatohepatitis. | 2020 | Details |
| A08886 | 31952573 | Adv Clin Chem | Organokines in disease. | 2019 | Details |
| A08890 | 31950811 | Acta Gastroenterol Belg | Impact of liver inflammation on whole body insulin resistance : a case report on primary biliary cholangitis. | 2020 | Details |
| A08891 | 31950772 | Diabetes Metab J | Combination of Probiotics and Salvia miltiorrhiza Polysaccharide Alleviates Hepatic Steatosis via Gut Microbiota Modulation and Insulin Resistance Improvement in High Fat-Induced NAFLD Mice. | 2019 | Details |
| A08894 | 31949886 | Oxid Med Cell Longev | Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism. | 2019 | Details |
| A08906 | 31943268 | Aliment Pharmacol Ther | Prevalence of significant hepatic fibrosis using magnetic resonance elastography in a health check-up clinic population. | 2020 | Details |
| A08913 | 31941015 | Int J Mol Sci | Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences. | 2020 | Details |
| A08923 | 31936799 | Cells | Diet, Gut Microbiota and Non-Alcoholic Fatty Liver Disease: Three Parts of the Same Axis. | 2020 | Details |
| A08925 | 31935815 | Int J Mol Sci | Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway. | 2020 | Details |
| A08928 | 31935149 | Crit Rev Clin Lab Sci | Fructose and hepatic insulin resistance. | 2020 | Details |
| A08934 | 31931541 | Z Gastroenterol | A young patient with type 2 diabetes associated non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. | 2020 | Details |
| A08938 | 31930835 | Pak J Biol Sci | FICK-3 Score Combining Fibrosis-4, Insulin Resistance and Cytokeratin-18 in Predicting Non-alcoholic Steatohepatitis in NAFLD Egyptian Patients. | 2019 | Details |
| A08945 | 31929840 | Dis Markers | Beta-3-adrenergic Receptor rs4994 Polymorphism Is a Potential Biomarker for the Development of Nonalcoholic Fatty Liver Disease in Overweight/Obese Individuals. | 2019 | Details |
| A08948 | 31928475 | Expert Opin Investig Drugs | NASH (nonalcoholic steatohepatitis), diabetes, and macrovascular disease: multiple chronic conditions and a potential treatment at the metabolic root. | 2020 | Details |
| A08954 | 31926984 | J Ethnopharmacol | Sweroside ameliorates NAFLD in high-fat diet induced obese mice through the regulation of lipid metabolism and inflammatory response. | 2020 | Details |
| A08955 | 31926452 | J Nutr Biochem | The nonalcoholic fatty liver disease-like phenotype and lowered serum VLDL are associated with decreased expression and DNA hypermethylation of hepatic ApoB in male offspring of ApoE deficient mothers fed a with Western diet. | 2019 | Details |
| A08963 | 31923578 | Diabetes Metab | Efficacy and safety of anti-hyperglycaemic drugs in patients with non-alcoholic fatty liver disease with or without diabetes: An updated systematic review of randomized controlled trials. | 2020 | Details |
| A08971 | 31920962 | Front Endocrinol (Lausanne) | Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases. | 2019 | Details |
| A08976 | 31918923 | Mol Metab | Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis. | 2019 | Details |
| A08984 | 31915606 | J Clin Transl Hepatol | Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A08998 | 31909773 | Food Funct | Baicalein reduces hepatic fat accumulation by activating AMPK in oleic acid-induced HepG2 cells and high-fat diet-induced non-insulin-resistant mice. | 2020 | Details |
| A09009 | 31905727 | Nutrients | Intestinal Fructose and Glucose Metabolism in Health and Disease. | 2019 | Details |
| A09026 | 31899984 | Expert Opin Investig Drugs | Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis. | 2020 | Details |
| A09028 | 31899128 | Ann Hepatol | Identification and study of differentially expressed miRNAs in aged NAFLD rats based on high-throughput sequencing. | 2019 | Details |
| A09037 | 31894585 | J Food Biochem | Royal jelly attenuates nonalcoholic fatty liver disease by inhibiting oxidative stress and regulating the expression of circadian genes in ovariectomized rats. | 2020 | Details |
| A09038 | 31894315 | Int J Mol Med | miR‑146a improves hepatic lipid and glucose metabolism by targeting MED1. | 2019 | Details |
| A09040 | 31893310 | Cell Mol Life Sci | Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism. | 2019 | Details |
| A09045 | 31890671 | J Diabetes Metab Disord | The effect of Nigella sativa oil on serum levels of inflammatory markers, liver enzymes, lipid profile, insulin and fasting blood sugar in patients with non-alcoholic fatty liver. | 2019 | Details |
| A09053 | 31888241 | Nutrients | Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial. | 2019 | Details |
| A09069 | 31885541 | Gastroenterol Res Pract | Systematic Review with Meta-Analysis: The Effects of Probiotics in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09070 | 31885103 | Fundam Clin Pharmacol | Comparative effectiveness of phosphodiesterase 3, 4, and 5 inhibitors in amelioration of high-fat diet-induced nonalcoholic fatty liver in rats. | 2020 | Details |
| A09078 | 31882889 | Sci Rep | Hepatic Mitochondrial Oxidative Metabolism and Lipogenesis Synergistically Adapt to Mediate Healthy Embryonic-to-Neonatal Transition in Chicken. | 2019 | Details |
| A09080 | 31882566 | Diabetes | The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH. | 2019 | Details |
| A09082 | 31882273 | J Diabetes Complications | Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements. | 2019 | Details |
| A09086 | 31881272 | Pharmacol Res | The gut-liver-kidney axis: Novel regulator of fatty liver associated chronic kidney disease. | 2019 | Details |
| A09098 | 31877412 | Mol Ther Nucleic Acids | Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. | 2019 | Details |
| A09099 | 31877356 | Free Radic Biol Med | The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress. | 2019 | Details |
| A09108 | 31870938 | Peptides | Endogenously released GIP reduces and GLP-1 increases hepatic insulin extraction. | 2019 | Details |
| A09113 | 31870087 | Korean J Pediatr | Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity. | 2019 | Details |
| A09119 | 31867441 | Hepatoma Res | Molecular links between non-alcoholic fatty liver disease and hepatocellular carcinoma. | 2019 | Details |
| A09120 | 31867105 | Cancer Metab | SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia. | 2019 | Details |
| A09121 | 31867104 | J Anim Sci Biotechnol | Hepatic metabolomics and transcriptomics to study susceptibility to ketosis in response to prepartal nutritional management. | 2019 | Details |
| A09127 | 31865317 | Dig Dis | Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. | 2019 | Details |
| A09130 | 31863731 | Exp Neurol | Hepatic dysfunction after spinal cord injury: A vicious cycle of central and peripheral pathology? | 2019 | Details |
| A09134 | 31862486 | J Hepatol | Clinical validation of the FLIP algorithm and the SAF score in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A09147 | 31858390 | Endocrine | Noninvasive assessment of hepatic steatosis and fibrosis in patients with severe obesity. | 2019 | Details |
| A09152 | 31857090 | Chem Biol Interact | Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity. | 2019 | Details |
| A09153 | 31856189 | PLoS One | Nonalcoholic fatty liver disease and hepatic fibrosis among perinatally HIV-monoinfected Asian adolescents receiving antiretroviral therapy. | 2019 | Details |
| A09157 | 31852748 | J Investig Med | Relationship between non-alcoholic fatty liver disease during pregnancy and abnormal glucose metabolism during and after pregnancy. | 2019 | Details |
| A09161 | 31852444 | BMC Gastroenterol | Effects of alternate-day fasting on body weight and dyslipidaemia in patients with non-alcoholic fatty liver disease: a randomised controlled trial. | 2019 | Details |
| A09171 | 31850288 | Front Pediatr | Metabolic Syndrome Is Associated With Advanced Liver Fibrosis Among Pediatric Patients With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09175 | 31847612 | Expert Opin Investig Drugs | The molecular basis for current targets of NASH therapies. | 2019 | Details |
| A09178 | 31847157 | Nutrients | Sarcopoterium spinosum Inhibited the Development of Non-Alcoholic Steatosis and Steatohepatitis in Mice. | 2019 | Details |
| A09184 | 31845054 | J Gastroenterol | Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives. | 2019 | Details |
| A09186 | 31843573 | J Ethnopharmacol | San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice models. | 2019 | Details |
| A09193 | 31840865 | Nutr Clin Pract | Evolution of NAFLD and Its Management. | 2019 | Details |
| A09194 | 31840531 | Clin Appl Thromb Hemost | Nonalcoholic Fatty Liver Disease and Thrombocytopenia III: Its Association With Insulin Resistance. | 2020 | Details |
| A09196 | 31839747 | Int J Med Sci | PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell. | 2019 | Details |
| A09201 | 31838076 | Gastroenterology | Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice. | 2019 | Details |
| A09203 | 31837337 | Life Sci | Prefrontal cortex inflammation and liver pathologies accompany cognitive and motor deficits following Western diet consumption in non-obese female mice. | 2019 | Details |
| A09206 | 31836013 | BMC Complement Altern Med | Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice. | 2019 | Details |
| A09213 | 31834465 | Naunyn Schmiedebergs Arch Pharmacol | NLRP3 inhibitor glibenclamide attenuates high-fat diet and streptozotocin-induced non-alcoholic fatty liver disease in rat: studies on oxidative stress, inflammation, DNA damage and insulin signalling pathway. | 2019 | Details |
| A09214 | 31834057 | Eur J Gastroenterol Hepatol | Serum visfatin level as a noninvasive marker for nonalcoholic fatty liver disease in children and adolescents with obesity: relation to transient elastography with controlled attenuation parameter. | 2020 | Details |
| A09216 | 31833787 | Epigenomics | Rat liver epigenome programing by perinatal exposure to 2,2',4'4'-tetrabromodiphenyl ether. | 2019 | Details |
| A09218 | 31832576 | Hepatol Commun | Insulin Resistance and Genetic Risk Predict Liver-Related Outcomes and Death in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09222 | 31832001 | World J Gastroenterol | LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway. | 2019 | Details |
| A09232 | 31826069 | J Gastrointestin Liver Dis | PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes. | 2019 | Details |
| A09242 | 31821039 | Am J Physiol Endocrinol Metab | Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism. | 2019 | Details |
| A09246 | 31819566 | Diabetes Metab Syndr Obes | Hepatic Steatosis Index Is Associated with Type 1 Diabetes Complications. | 2019 | Details |
| A09249 | 31817648 | Nutrients | High Protein Diet and Metabolic Plasticity in Non-Alcoholic Fatty Liver Disease: Myths and Truths. | 2019 | Details |
| A09250 | 31817623 | J Clin Med | Higher Sodium Intake Assessed by 24 Hour Urinary Sodium Excretion Is Associated with Non-Alcoholic Fatty Liver Disease: The PREVEND Cohort Study. | 2019 | Details |
| A09255 | 31816412 | Biochim Biophys Acta Mol Cell Biol Lipids | Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition. | 2019 | Details |
| A09259 | 31814783 | Hepat Med | A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A09272 | 31809318 | Chin Med J (Engl) | Association of leukocyte telomere length with non-alcoholic fatty liver disease in patients with type 2 diabetes. | 2019 | Details |
| A09278 | 31808322 | J Korean Med Sci | Correlation of Clinical and Histopathologic Parameters with Ultrasonographic Grades in Pediatric Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09280 | 31808097 | Environ Sci Pollut Res Int | Could phthalates exposure contribute to the development of metabolic syndrome and liver disease in humans? | 2019 | Details |
| A09281 | 31807383 | Cureus | Effect of Non-alcoholic Fatty Liver Disease on Transaminase Levels and Transient Elastography in Patients with Chronic Hepatitis B. | 2019 | Details |
| A09284 | 31805951 | Lipids Health Dis | Target genes associated with lipid and glucose metabolism in non-alcoholic fatty liver disease. | 2019 | Details |
| A09285 | 31805752 | Molecules | Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models. | 2019 | Details |
| A09287 | 31805072 | PLoS One | Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Leprdb/J mouse model of non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |