Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A05894 | 33084982 | Acta Diabetol | Association of 1-deoxy-sphingolipids with steatosis but not steatohepatitis nor fibrosis in non-alcoholic fatty liver disease. | 2020 | Details |
| A05897 | 33083254 | J Clin Transl Hepatol | Antihepatic Fibrosis Drugs in Clinical Trials. | 2020 | Details |
| A05906 | 33079776 | Eur J Gastroenterol Hepatol | A prospective cohort study of the use of the fatty liver index and Fibroscan to determine the prevalence of fatty liver disease in an Irish population. | 2022 | Details |
| A05908 | 33079307 | Arch Pharm Res | Emerging roles of ferroptosis in liver pathophysiology. | 2020 | Details |
| A05911 | 33078424 | J Food Biochem | Role of potato protein hydrolysate and exercise in preventing high-fat diet-induced hepatocyte apoptosis in senescence-accelerated mouse. | 2020 | Details |
| A05924 | 33074035 | Expert Opin Investig Drugs | The nonalcoholic steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future success. | 2020 | Details |
| A05925 | 33073962 | Clin Lab | Serum Thyroid Hormones Levels are Significantly Associated with Nonalcoholic Fatty Liver Disease in Euthyroid Chinese Population. | 2020 | Details |
| A05927 | 33073044 | Transl Gastroenterol Hepatol | Pathogenesis and pathways: nonalcoholic fatty liver disease & alcoholic liver disease. | 2020 | Details |
| A05928 | 33072790 | Front Med (Lausanne) | Roles of Macrophages and Exosomes in Liver Diseases. | 2020 | Details |
| A05931 | 33072455 | Cureus | Pleiotropic Effects of Statins in the Light of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05938 | 33070425 | Int J Clin Pract | Relationship between coffee consumption, sleep duration and smoking status with elastographic parameters of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements. | 2020 | Details |
| A05941 | 33069882 | Clin Gastroenterol Hepatol | Expert Panel Review on Nonalcoholic Fatty Liver Disease in Persons With Human Immunodeficiency Virus. | 2020 | Details |
| A05946 | 33067533 | Sci Rep | HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. | 2020 | Details |
| A05949 | 33066113 | Int J Mol Sci | Chymase as a Possible Therapeutic Target for Amelioration of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05959 | 33061687 | Hepat Med | Efficacy of Glucagon-Like Peptide-1 Analogs in Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2020 | Details |
| A05960 | 33061293 | Drug Des Devel Ther | Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice. | 2020 | Details |
| A05966 | 33059584 | BMC Gastroenterol | Carbon tetrachloride (CCl4) accelerated development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH) in MS-NASH mice fed western diet supplemented with fructose (WDF). | 2020 | Details |
| A05967 | 33059580 | Curr Vasc Pharmacol | Prevalence, Diagnosis, and Treatment with 3 Different Statins of Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis in Military Personnel. Do Genetics Play a Role? | 2021 | Details |
| A05974 | 33055315 | Rom J Intern Med | Association between serum interleukin (IL)-12 level and severity of non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A05981 | 33053631 | Nutrients | Microbiota, Fiber, and NAFLD: Is There Any Connection? | 2020 | Details |
| A05982 | 33052552 | Obes Surg | Bariatric Surgery in Nonalcoholic Fatty Liver Disease (NAFLD): Impact Assessment Using Paired Liver Biopsy and Fibroscan. | 2020 | Details |
| A05984 | 33051603 | Nat Rev Gastroenterol Hepatol | Maladaptive regeneration - the reawakening of developmental pathways in NASH and fibrosis. | 2020 | Details |
| A05988 | 33050067 | Biomolecules | Pharmaceutical Efficacy of Gypenoside LXXV on Non-Alcoholic Steatohepatitis (NASH). | 2020 | Details |
| A05998 | 33045403 | Contemp Clin Trials | The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease. | 2020 | Details |
| A05999 | 33045214 | Life Sci | Evolutionary conservation of long non-coding RNAs in non-alcoholic fatty liver disease. | 2020 | Details |
| A06003 | 33040692 | Trop Doct | Effects of anthropometric and metabolic parameters on transaminase levels and liver stiffness in patients with non-alcohol fatty liver disease. | 2020 | Details |
| A06005 | 33039693 | Contemp Clin Trials | Semaglutide for the treatment of non-alcoholic steatohepatitis: Trial design and comparison of non-invasive biomarkers. | 2020 | Details |
| A06006 | 33039155 | Clin Nutr | Association between blood copper and nonalcoholic fatty liver disease according to sex. | 2020 | Details |
| A06009 | 33038502 | Contemp Clin Trials | A randomised, double-blind, placebo-controlled, multi-centre, dose-range, proof-of-concept, 24-week treatment study of lanifibranor in adult subjects with non-alcoholic steatohepatitis: Design of the NATIVE study. | 2020 | Details |
| A06010 | 33038434 | J Hepatol | Role of CC chemokine receptor 9 in the progression of murine and human non-alcoholic steatohepatitis. | 2020 | Details |
| A06012 | 33038431 | J Hepatol | Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features. | 2020 | Details |
| A06016 | 33037768 | Liver Int | Intestinal permeability in human nonalcoholic fatty liver disease: A systematic review and meta-analysis. | 2020 | Details |
| A06021 | 33037056 | Gut | Mortality in biopsy-confirmed nonalcoholic fatty liver disease: results from a nationwide cohort. | 2020 | Details |
| A06023 | 33036418 | Diagnostics (Basel) | Optimization of Point-Shear Wave Elastography by Skin-to-Liver Distance to Assess Liver Fibrosis in Patients Undergoing Bariatric Surgery. | 2020 | Details |
| A06024 | 33036387 | Cells | Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings. | 2020 | Details |
| A06025 | 33036257 | Cells | Playing Jekyll and Hyde-The Dual Role of Lipids in Fatty Liver Disease. | 2020 | Details |
| A06029 | 33034671 | Abdom Radiol (NY) | Quantification of liver function using gadoxetic acid-enhanced MRI. | 2020 | Details |
| A06032 | 33033573 | World J Hepatol | Non-alcoholic fatty liver disease later diagnosed as myotonic dystrophy. | 2020 | Details |
| A06038 | 33032263 | J Endocrinol | Lactobacillus pentosus strain S-PT84 improves steatohepatitis by maintaining gut permeability. | 2020 | Details |
| A06043 | 33031439 | PLoS One | In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19. | 2020 | Details |
| A06044 | 33030804 | J Diabetes Investig | Association of the Non-Alcoholic Fatty Liver Disease Fibrosis Score with subclinical myocardial remodeling in patients with type 2 diabetes: A cross-sectional study in China. | 2021 | Details |
| A06049 | 33028338 | Lipids Health Dis | The triglyceride-glucose index is associated with the severity of hepatic steatosis and the presence of liver fibrosis in non-alcoholic fatty liver disease: a cross-sectional study in Chinese adults. | 2020 | Details |
| A06054 | 33027082 | Am J Gastroenterol | Effects of Statin Use on the Development and Progression of Nonalcoholic Fatty Liver Disease: A Nationwide Nested Case-Control Study. | 2021 | Details |
| A06055 | 33026561 | EJNMMI Res | Quantitative evaluation of hepatic integrin αvβ3 expression by positron emission tomography imaging using 18F-FPP-RGD2 in rats with non-alcoholic steatohepatitis. | 2020 | Details |
| A06056 | 33026380 | Food Funct | Gut inflammation exacerbates hepatic injury in C57BL/6J mice via gut-vascular barrier dysfunction with high-fat-incorporated meat protein diets. | 2020 | Details |
| A06059 | 33025153 | Abdom Radiol (NY) | Liver fat quantification: where do we stand? | 2020 | Details |
| A06060 | 33024915 | Hepatol Commun | Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice. | 2020 | Details |
| A06062 | 33024913 | Hepatol Commun | Differential Outcomes and Clinical Challenges of NAFLD With Extreme Obesity. | 2020 | Details |
| A06063 | 33024911 | Hepatol Commun | Developmental Programming of NAFLD by Parental Obesity. | 2020 | Details |
| A06067 | 33022942 | Life (Basel) | Plasma Long Noncoding RNA LeXis is a Potential Diagnostic Marker for Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A06069 | 33020474 | Nat Commun | Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD. | 2020 | Details |
| A06073 | 33016540 | Aliment Pharmacol Ther | Patterns and predictors of mortality and disease progression among patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06074 | 33015726 | Curr Diab Rep | Role of Agents for the Treatment of Diabetes in the Management of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06077 | 33014604 | Biomed Opt Express | Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine model for nonalcoholic fatty liver disease. | 2020 | Details |
| A06080 | 33013934 | Front Immunol | CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice. | 2020 | Details |
| A06087 | 33011499 | Diabetes Metab Syndr | Comparative effectiveness of glucagon-like peptide-1 receptor agonists versus dipeptidyl peptidase-4 inhibitors on noninvasive indices of hepatic steatosis and fibrosis in patients with type 2 diabetes mellitus. | 2020 | Details |
| A06090 | 33010412 | Clin Gastroenterol Hepatol | Testosterone is Associated With Nonalcoholic Steatohepatitis and Fibrosis in Premenopausal Women With NAFLD. | 2020 | Details |
| A06091 | 33010409 | Clin Gastroenterol Hepatol | Liver Stiffness by Magnetic Resonance Elastography Predicts Future Cirrhosis, Decompensation, and Death in NAFLD. | 2020 | Details |
| A06096 | 33009010 | AIDS | Liver steatosis and nonalcoholic fatty liver disease with fibrosis are predictors of frailty in people living with HIV. | 2020 | Details |
| A06102 | 33007418 | Pharmacol Res | Endoplasmic reticulum stress and protein degradation in chronic liver disease. | 2020 | Details |
| A06106 | 33006125 | Adv Ther | Clinical Characteristics of a Non-Alcoholic Fatty Liver Disease Population Across the Fibrosis Spectrum Measured by Magnetic Resonance Elastography: Analysis of Screening Data. | 2020 | Details |
| A06113 | 33002003 | PLoS One | REV-ERB agonism improves liver pathology in a mouse model of NASH. | 2020 | Details |
| A06120 | 32998257 | Cancers (Basel) | Hepatocellular Carcinoma and Non-Alcoholic Fatty Liver Disease: A Step Forward for Better Evaluation Using Ultrasound Elastography. | 2020 | Details |
| A06123 | 32997882 | Liver Int | MAFLD identifies patients with significant hepatic fibrosis better than NAFLD. | 2020 | Details |
| A06129 | 32995080 | PeerJ | Association between serum and dietary antioxidant micronutrients and advanced liver fibrosis in non-alcoholic fatty liver disease: an observational study. | 2020 | Details |
| A06142 | 32991173 | J Med Chem | Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06148 | 32987175 | Ann Hepatol | Outcomes of Japanese patients with non-alcoholic fatty liver disease according to genetic background and lifestyle-related diseases. | 2020 | Details |
| A06149 | 32987153 | Cell Mol Gastroenterol Hepatol | Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy. | 2020 | Details |
| A06151 | 32986864 | Hepatology | Osteopontin Takes Center Stage in Chronic Liver Disease. | 2021 | Details |
| A06153 | 32985239 | Nat Prod Res | Hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis Fisch in liver injury mice. | 2020 | Details |
| A06154 | 32984925 | Curr HIV/AIDS Rep | NASH in HIV. | 2020 | Details |
| A06156 | 32984364 | Front Med (Lausanne) | Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases. | 2020 | Details |
| A06159 | 32982495 | Hepat Med | Identifying High-Risk NASH Patients: What We Know so Far. | 2020 | Details |
| A06160 | 32982365 | Clin Exp Gastroenterol | Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats. | 2020 | Details |
| A06162 | 32982112 | World J Gastroenterol | Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation. | 2020 | Details |
| A06164 | 32981386 | Expert Rev Clin Pharmacol | The pharmacological treatment of nonalcoholic fatty liver disease in children. | 2020 | Details |
| A06166 | 32981113 | Aliment Pharmacol Ther | Digital pathology: accurate technique for quantitative assessment of histological features in metabolic-associated fatty liver disease. | 2020 | Details |
| A06167 | 32981002 | Obes Surg | The Use of Transient Elastography Technology in the Bariatric Patient: a Review of the Literature. | 2020 | Details |
| A06169 | 32980849 | Cerebrovasc Dis | Advanced Liver Fibrosis Predicts Unfavorable Long-Term Prognosis in First-Ever Ischemic Stroke or Transient Ischemic Attack. | 2020 | Details |
| A06170 | 32980687 | Cytokine | CAT1 silencing inhibits TGF-β1-induced mouse hepatic stellate cell activation in vitro and hepatic fibrosis in vivo. | 2020 | Details |
| A06176 | 32978907 | Acta Sci Pol Technol Aliment | Coffee and nonalcoholic fatty liver disease: A review. | 2021 | Details |
| A06177 | 32978796 | Hepatology | ABIDE: An Accurate Predictive Model of Liver Decompensation in Patients With Nonalcoholic Fatty Liver-Related Cirrhosis. | 2021 | Details |
| A06178 | 32978491 | Sci Rep | FIB-4 index is a marker for a subsequent decrease in insulin secretion in a non-diabetic Japanese population. | 2020 | Details |
| A06182 | 32977558 | Molecules | Distinct Influence of Hypercaloric Diets Predominant with Fat or Fat and Sucrose on Adipose Tissue and Liver Inflammation in Mice. | 2020 | Details |
| A06183 | 32977490 | Cells | The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging. | 2020 | Details |
| A06186 | 32977024 | Pharmacol Res | The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease. | 2020 | Details |
| A06189 | 32976186 | Eur J Gastroenterol Hepatol | Accuracy of Fibrosis-4 index and non-alcoholic fatty liver disease fibrosis scores in metabolic (dysfunction) associated fatty liver disease according to body mass index: failure in the prediction of advanced fibrosis in lean and morbidly obese individuals. | 2022 | Details |
| A06190 | 32975679 | Adv Ther | Effect of Empagliflozin on Liver Steatosis and Fibrosis in Patients With Non-Alcoholic Fatty Liver Disease Without Diabetes: A Randomized, Double-Blind, Placebo-Controlled Trial. | 2020 | Details |
| A06192 | 32975060 | Yonsei Med J | Association between Atrial Fibrillation and Advanced Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06195 | 32973925 | Therap Adv Gastroenterol | The role of the gut microbiome and exercise in non-alcoholic fatty liver disease. | 2020 | Details |
| A06199 | 32971586 | Clin Mol Hepatol | The effect of moderate alcohol drinking in nonalcoholic fatty liver disease. | 2020 | Details |
| A06203 | 32970896 | Clin Transplant | Association between obesity after liver transplantation and steatosis, inflammation, and fibrosis of the graft. | 2020 | Details |
| A06205 | 32968123 | Sci Rep | Automated thermal imaging for the detection of fatty liver disease. | 2020 | Details |
| A06212 | 32965675 | Hepatology | Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A06214 | 32964989 | Eur Rev Med Pharmacol Sci | HSD17B13 rs72613567 protects against liver diseases and histological progression of nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2020 | Details |
| A06216 | 32964202 | JHEP Rep | Contribution of sarcopenia and physical inactivity to mortality in people with non-alcoholic fatty liver disease. | 2020 | Details |
| A06217 | 32964201 | JHEP Rep | The Fatty Liver Assessment in Germany (FLAG) cohort study identifies large heterogeneity in NAFLD care. | 2020 | Details |
| A06226 | 32961796 | Int J Mol Sci | miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A06236 | 32959331 | Obes Surg | Applicability and Results of Liver Stiffness Measurement and Controlled Attenuation Parameter Using XL Probe for Metabolic-Associated Fatty Liver Disease in Candidates to Bariatric Surgery. A Single-Center Observational Study. | 2020 | Details |
| A06239 | 32957701 | Biomolecules | Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver. | 2020 | Details |