Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11428 | 30898698 | Gene | Long noncoding RNA Mirt2 upregulates USP10 expression to suppress hepatic steatosis by sponging miR-34a-5p. | 2019 | Details |
| A11430 | 30897538 | Biomed Pharmacother | Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease. | 2019 | Details |
| A11436 | 30896868 | Mol Med Rep | Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats. | 2019 | Details |
| A11439 | 30895694 | Phytother Res | The clinical effects of purslane (Portulaca oleracea) seeds on metabolic profiles in patients with nonalcoholic fatty liver disease: A randomized controlled clinical trial. | 2019 | Details |
| A11441 | 30893108 | Curr Opin Lipidol | Bile acid alterations in nonalcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes: what do the human studies tell? | 2019 | Details |
| A11442 | 30893090 | Curr Opin Clin Nutr Metab Care | Sarcopenic obesity in fatty liver. | 2019 | Details |
| A11443 | 30892882 | J Agric Food Chem | Preventive Efficiency of Green Tea and Its Components on Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11446 | 30891617 | J Mol Med (Berl) | Innate immune regulatory networks in hepatic lipid metabolism. | 2019 | Details |
| A11451 | 30889343 | Rev Med Inst Mex Seguro Soc | Nonalcoholic hepatic steatosis: a silent disease | 2019 | Details |
| A11457 | 30888440 | Intensive Care Med | Obesity in the critically ill: a narrative review. | 2019 | Details |
| A11463 | 30885145 | BMC Gastroenterol | The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose. | 2019 | Details |
| A11473 | 30881473 | Evid Based Complement Alternat Med | Jwa Kum Whan Attenuates Nonalcoholic Fatty Liver Disease by Modulating Glucose Metabolism and the Insulin Signaling Pathway. | 2019 | Details |
| A11474 | 30881345 | Front Endocrinol (Lausanne) | Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease. | 2019 | Details |
| A11477 | 30879920 | EBioMedicine | Arid1a regulates insulin sensitivity and lipid metabolism. | 2019 | Details |
| A11478 | 30879098 | Eur J Nutr | Moderate consumption of fermented alcoholic beverages diminishes diet-induced non-alcoholic fatty liver disease through mechanisms involving hepatic adiponectin signaling in mice. | 2019 | Details |
| A11480 | 30878016 | J Endocrinol | Short-term strength training reduces gluconeogenesis and NAFLD in obese mice. | 2019 | Details |
| A11481 | 30877708 | Diabetes Metab J | Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus. | 2019 | Details |
| A11492 | 30872135 | Arab J Gastroenterol | Relationship between lifestyle factors and nutritional status and non-alcoholic fatty liver disease among a group of adult Jordanians. | 2019 | Details |
| A11494 | 30871514 | BMC Complement Altern Med | Green cardamom supplementation improves serum irisin, glucose indices, and lipid profiles in overweight or obese non-alcoholic fatty liver disease patients: a double-blind randomized placebo-controlled clinical trial. | 2019 | Details |
| A11499 | 30870804 | Nutrition | Cancer-related gene expression is associated with disease severity and modifiable lifestyle factors in non-alcoholic fatty liver disease. | 2018 | Details |
| A11500 | 30870486 | PLoS One | Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects. | 2019 | Details |
| A11506 | 30867987 | PeerJ | Comparison of laboratory indices of non-alcoholic fatty liver disease for the detection of incipient kidney dysfunction. | 2019 | Details |
| A11522 | 30860877 | Am J Physiol Endocrinol Metab | Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice. | 2019 | Details |
| A11528 | 30856468 | J Nutr Biochem | Tissue-dependent effects of cis-9,trans-11- and trans-10,cis-12-CLA isomers on glucose and lipid metabolism in adult male mice. | 2019 | Details |
| A11543 | 30850619 | Sci Rep | Voluntary exercise in mice fed an obesogenic diet alters the hepatic immune phenotype and improves metabolic parameters - an animal model of life style intervention in NAFLD. | 2019 | Details |
| A11544 | 30850262 | Trends Endocrinol Metab | Calcium Signaling As a Therapeutic Target for Liver Steatosis. | 2019 | Details |
| A11548 | 30848932 | FASEB J | Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3. | 2019 | Details |
| A11549 | 30848827 | J Clin Endocrinol Metab | Plasma Fibroblast Growth Factor 21 Is Associated With Severity of Nonalcoholic Steatohepatitis in Patients With Obesity and Type 2 Diabetes. | 2019 | Details |
| A11557 | 30841472 | Biomed Pharmacother | Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue. | 2019 | Details |
| A11558 | 30841442 | Biomed Pharmacother | Genistein can ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis rats. | 2019 | Details |
| A11563 | 30838350 | Acta Myol | Prevalence of metabolic syndrome and non-alcoholic fatty liver disease in a cohort of italian patients with spinal-bulbar muscular atrophy. | 2018 | Details |
| A11564 | 30837878 | Front Pharmacol | G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases. | 2019 | Details |
| A11567 | 30836637 | Nutrients | Similar Weight Loss Induces Greater Improvements in Insulin Sensitivity and Liver Function among Individuals with NAFLD Compared to Individuals without NAFLD. | 2019 | Details |
| A11574 | 30833801 | World J Gastroenterol | Procyanidin B2 protects against diet-induced obesity and non-alcoholic fatty liver disease via the modulation of the gut microbiota in rabbits. | 2019 | Details |
| A11575 | 30833214 | Clin Nutr | Non-alcoholic fatty liver in hereditary fructose intolerance. | 2019 | Details |
| A11577 | 30832745 | Br J Nutr | Dietary determinants of hepatic fat content and insulin resistance in overweight/obese children: a cross-sectional analysis of the Prevention of Diabetes in Kids (PREDIKID) study. | 2019 | Details |
| A11578 | 30832722 | Trials | Effects of vitamin D supplementation on liver fibrogenic factors in non-alcoholic fatty liver patients with steatohepatitis: study protocol for a randomized clinical trial. | 2019 | Details |
| A11581 | 30831319 | Cell Mol Gastroenterol Hepatol | Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis. | 2019 | Details |
| A11587 | 30828530 | Adv Sci (Weinh) | Insights into the Epidemiology, Pathogenesis, and Therapeutics of Nonalcoholic Fatty Liver Diseases. | 2018 | Details |
| A11592 | 30826497 | Life Sci | Interrelation of liver vascularity to non-alcoholic fatty liver through a comparative study of the vasodilator effect of carvedilol or nicorandil in rats. | 2019 | Details |
| A11609 | 30820969 | Hepatology | Dual Specificity Phosphatase 12 Regulates Hepatic Lipid Metabolism Through Inhibition of the Lipogenesis and Apoptosis Signal-Regulating Kinase 1 Pathways. | 2019 | Details |
| A11611 | 30820265 | World J Hepatol | Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects. | 2019 | Details |
| A11613 | 30819364 | J Am Coll Cardiol | Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review. | 2019 | Details |
| A11618 | 30818779 | Nutrients | Green Coffee Extract Improves Cardiometabolic Parameters and Modulates Gut Microbiota in High-Fat-Diet-Fed ApoE-/- Mice. | 2019 | Details |
| A11623 | 30814508 | Nat Commun | Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism. | 2019 | Details |
| A11635 | 30810254 | Int J Clin Pract | Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease. | 2019 | Details |
| A11640 | 30809151 | Front Physiol | LSEC Fenestrae Are Preserved Despite Pro-inflammatory Phenotype of Liver Sinusoidal Endothelial Cells in Mice on High Fat Diet. | 2019 | Details |
| A11663 | 30798598 | J Agric Food Chem | Intestinal Barrier Function-Non-alcoholic Fatty Liver Disease Interactions and Possible Role of Gut Microbiota. | 2019 | Details |
| A11670 | 30796508 | Eur J Nutr | Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo-controlled clinical trial. | 2019 | Details |
| A11697 | 30788048 | World J Diabetes | SGLT-2 inhibitors in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: A systematic review. | 2019 | Details |
| A11698 | 30787925 | Front Immunol | The Differential Roles of T Cells in Non-alcoholic Fatty Liver Disease and Obesity. | 2019 | Details |
| A11721 | 30777418 | Rev Med Inst Mex Seguro Soc | Molecular alterations induced by fructose and its impact on metabolic diseases | 2019 | Details |
| A11723 | 30776292 | J Clin Endocrinol Metab | Comorbidities in primary versus secondary school children with obesity and responsiveness to lifestyle intervention. | 2019 | Details |
| A11728 | 30774403 | Diabetes Metab Syndr Obes | The fatty liver index, a simple and useful predictor of metabolic syndrome: analysis of the Korea National Health and Nutrition Examination Survey 2010-2011. | 2019 | Details |
| A11731 | 30773673 | Clin Exp Pharmacol Physiol | Resveratrol protects against hepatic insulin resistance in a rat's model of non-alcoholic fatty liver disease by down-regulation of GPAT-1 and DGAT2 expression and inhibition of PKC membranous translocation. | 2019 | Details |
| A11741 | 30770030 | Diab Vasc Dis Res | Insulin resistance and insulin hypersecretion in the metabolic syndrome and type 2 diabetes: Time for a conceptual framework shift. | 2019 | Details |
| A11743 | 30769284 | Redox Biol | Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis. | 2019 | Details |
| A11745 | 30768879 | Klin Lab Diagn | [The person in philogenesis is not (omnivores), but the herbivores with the carnivores past and the fuzzy future. Biological function of trophology (nutrition) in ontogenesis.] | 2019 | Details |
| A11749 | 30766961 | Hepatol Commun | Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity. | 2018 | Details |
| A11750 | 30766955 | Hepatol Commun | Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine. | 2019 | Details |
| A11758 | 30763699 | Diabetes Metab | Association between PNPLA3rs738409 polymorphism decreased kidney function in postmenopausal type 2 diabetic women with or without non-alcoholic fatty liver disease. | 2019 | Details |
| A11761 | 30762938 | Mol Nutr Food Res | Jamun (Eugenia jambolana Lam.) Fruit Extract Prevents Obesity by Modulating the Gut Microbiome in High-Fat-Diet-Fed Mice. | 2019 | Details |
| A11769 | 30758417 | Rev Assoc Med Bras (1992) | The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data. | 2019 | Details |
| A11780 | 30746959 | Rev Esp Enferm Dig | Comparative study of overweight and obese patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A11784 | 30745819 | Int J Biol Sci | Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates. | 2019 | Details |
| A11786 | 30745416 | J Pharmacol Exp Ther | RLA8-A New and Highly Effective Quadruple PPAR-α/γ/δ and GPR40 Agonist to Reverse Nonalcoholic Steatohepatitis and Fibrosis. | 2019 | Details |
| A11805 | 30732664 | Proc Nutr Soc | Understanding susceptibility and targeting treatment in non-alcoholic fatty liver disease in children; moving the fulcrum. | 2019 | Details |
| A11806 | 30732555 | Eur J Sport Sci | Mechanisms of beneficial effects of exercise training on non-alcoholic fatty liver disease (NAFLD): Roles of oxidative stress and inflammation. | 2019 | Details |
| A11808 | 30731283 | Atherosclerosis | Does nonalcoholic fatty liver disease cause cardiovascular disease? Current knowledge and gaps. | 2019 | Details |
| A11819 | 30721562 | Liver Int | MicroRNA-30b regulates insulin sensitivity by targeting SERCA2b in non-alcoholic fatty liver disease. | 2019 | Details |
| A11843 | 30711017 | Lipids Health Dis | Triglycerides to high-density lipoprotein cholesterol ratio as a surrogate for nonalcoholic fatty liver disease: a cross-sectional study. | 2019 | Details |
| A11848 | 30708259 | Nutrition | Dietary patterns and non-alcoholic fatty liver disease in a Greek case-control study. | 2018 | Details |
| A11853 | 30708053 | Nanomedicine | Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis. | 2019 | Details |
| A11862 | 30705687 | Nutr Metab (Lond) | Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial. | 2019 | Details |
| A11869 | 30703416 | Pharmacol Ther | Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders. | 2019 | Details |
| A11870 | 30702924 | Appl Physiol Nutr Metab | Sex-based differences in hepatic and skeletal muscle triglyceride storage and metabolism 1. | 2019 | Details |
| A11871 | 30701940 | Ter Arkh | The clinical significance of insulin resistance in non-diabetic patients with early forms of non-alcoholic fatty liver disease. | 2018 | Details |
| A11874 | 30701776 | Ter Arkh | Intrahepatic cholestasis in nonalcoholic fatty liver disease. | 2018 | Details |
| A11878 | 30700810 | Sci Rep | Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease. | 2019 | Details |
| A11881 | 34267963 | Florence Nightingale Hemsire Derg | [Is There an Effect of Dietary Fructose on Development and Prognosis of Chronic Diseases?] | 2019 | Details |
| A11882 | 30697898 | Liver Int | The interaction of nonalcoholic fatty liver disease and smoking on mortality among adults in the United States. | 2019 | Details |
| A11890 | 30692925 | Front Pharmacol | Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues. | 2019 | Details |
| A11892 | 30691985 | Endocrinol Diabetes Nutr (Engl Ed) | Role of neuropeptide Y gene variant (rs161477) in liver histology in obese patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A11922 | 30680920 | Mol Nutr Food Res | Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High-Fat Diet Determine Non-Alcoholic Fatty Liver Disease Development in Germ-Free Mice. | 2019 | Details |
| A11925 | 30680007 | Exp Ther Med | Effects of liver function, insulin resistance and inflammatory factors on vascular endothelial dilation function and prognosis of coronary heart disease patients complicated with NAFLD. | 2018 | Details |
| A11928 | 30678506 | J Int Med Res | Protective role of arnebin-1 in rats with nonalcoholic fatty liver disease. | 2019 | Details |
| A11935 | 30674511 | Can Fam Physician | Omega-3 for nonalcoholic fatty liver disease in children. | 2019 | Details |
| A11937 | 30673851 | Med Mol Morphol | The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression. | 2019 | Details |
| A11938 | 30673802 | Diabetologia | The PNPLA3 rs738409 C>G variant interacts with changes in body weight over time to aggravate liver steatosis, but reduces the risk of incident type 2 diabetes. | 2019 | Details |
| A11939 | 30673698 | PLoS One | Decreased lung function is associated with risk of developing non-alcoholic fatty liver disease: A longitudinal cohort study. | 2019 | Details |
| A11945 | 30671426 | Front Pediatr | Novel Ultrasonographic Fatty Liver Indicator Can Predict Hepatitis in Children With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A11951 | 30670819 | Nat Rev Endocrinol | Gut microbial metabolites in obesity, NAFLD and T2DM. | 2019 | Details |
| A11958 | 30668424 | Phytomedicine | Lycopus lucidus Turcz. ex Benth. Attenuates free fatty acid-induced steatosis in HepG2 cells and non-alcoholic fatty liver disease in high-fat diet-induced obese mice. | 2018 | Details |
| A11959 | 30668392 | Phytomedicine | Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor. | 2018 | Details |
| A11967 | 30664220 | Int J Mol Med | SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPARα/FoxO1 signaling pathway. | 2019 | Details |
| A11970 | 30662331 | Int J Med Sci | Ultrasound/Elastography techniques, lipidomic and blood markers compared to Magnetic Resonance Imaging in non-alcoholic fatty liver disease adults. | 2019 | Details |
| A11975 | 30660761 | Diabetes Metab | Insulin resistance and NAFLD: Relationship with intrahepatic iron and serum TNF-α using 1H MR spectroscopy and MRI. | 2019 | Details |
| A11979 | 30659533 | Curr Pharm Des | Genetics of Nonalcoholic Fatty Liver Disease: A 2018 Update. | 2018 | Details |
| A11984 | 30658483 | Nutrients | A Randomized, Controlled Trial of Vitamin D Supplementation on Cardiovascular Risk Factors, Hormones, and Liver Markers in Women with Polycystic Ovary Syndrome. | 2019 | Details |
| A11992 | 30654392 | Semin Liver Dis | NASH in Lean Individuals. | 2019 | Details |