Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12147 | 30582764 | Hepatology | Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. | 2019 | Details |
| A12150 | 30581002 | Biochem Biophys Res Commun | Secreted modular calcium-binding protein 2 promotes high fat diet (HFD)-induced hepatic steatosis through enhancing lipid deposition, fibrosis and inflammation via targeting TGF-β1. | 2018 | Details |
| A12151 | 30580671 | Lab Anim | The role of gut microbiota in intestinal and liver diseases. | 2018 | Details |
| A12159 | 30578461 | Adv Exp Med Biol | Fighting Fatty Liver Diseases with Nutritional Interventions, Probiotics, Symbiotics, and Fecal Microbiota Transplantation (FMT). | 2019 | Details |
| A12166 | 30576769 | Cell Mol Gastroenterol Hepatol | Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12171 | 30576244 | Am J Physiol Endocrinol Metab | Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments. | 2018 | Details |
| A12184 | 30572006 | J Hepatol | Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish. | 2018 | Details |
| A12202 | 30563997 | J Clin Exp Hepatol | Biopsy Proven Fibrosis in Non-Alcoholic Fatty Liver Disease: An Analysis of Risk Factors. | 2018 | Details |
| A12220 | 30557902 | Diabetes Metab Res Rev | Apolipoprotein CIII and diabetes. Is there a link? | 2019 | Details |
| A12240 | 30551380 | Biomed Pharmacother | Preventive effect of trans-chalcone on non-alcoholic steatohepatitis: Improvement of hepatic lipid metabolism. | 2018 | Details |
| A12255 | 30544824 | Int J Mol Sci | Oleuropein Induces AMPK-Dependent Autophagy in NAFLD Mice, Regardless of the Gender. | 2018 | Details |
| A12258 | 30543782 | Chem Biol Interact | Subterminal hydroxyeicosatetraenoic acids: Crucial lipid mediators in normal physiology and disease states. | 2018 | Details |
| A12259 | 30543441 | Mol Pharm | Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice. | 2018 | Details |
| A12270 | 30540086 | Arq Gastroenterol | CORRELATION BETWEEN NONALCOHOLIC FATTY LIVER DISEASE FEATURES AND LEVELS OF ADIPOKINES AND INFLAMMATORY CYTOKINES AMONG MORBIDLY OBESE INDIVIDUALS. | 2019 | Details |
| A12271 | 30539788 | Cell Mol Gastroenterol Hepatol | Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12273 | 30538805 | Oxid Med Cell Longev | c-Met Signaling Protects from Nonalcoholic Steatohepatitis- (NASH-) Induced Fibrosis in Different Liver Cell Types. | 2018 | Details |
| A12274 | 30538803 | Oxid Med Cell Longev | Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet-Induced Accumulation of Lipid in the Liver of ApoE-/- Mice. | 2018 | Details |
| A12279 | 30536914 | J Physiol | Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions. | 2019 | Details |
| A12287 | 30529260 | Food Chem Toxicol | Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects. | 2018 | Details |
| A12304 | 30508523 | Biochem Pharmacol | Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease. | 2018 | Details |
| A12318 | 30516830 | Hepatology | Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages. | 2019 | Details |
| A12320 | 30516498 | Georgian Med News | EFFECTIVENESS OF NONALCOHOLIC STEATOHEPATITIS CORRECTION ON THE BAСKGROUND OF OBESITY WITH CONCOMITANT CHRONIC KIDNEY DISEASE. | 2018 | Details |
| A12330 | 30512987 | Am J Physiol Endocrinol Metab | Estrogen receptor-α signaling maintains immunometabolic function in males and is obligatory for exercise-induced amelioration of nonalcoholic fatty liver. | 2018 | Details |
| A12336 | 30509561 | J Formos Med Assoc | Gut microbiota and pediatric obesity/non-alcoholic fatty liver disease. | 2018 | Details |
| A12373 | 30482910 | Nat Rev Gastroenterol Hepatol | The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2019 | Details |
| A12376 | 30481403 | IUBMB Life | IL-17A-mediated ERK1/2/p65 signaling pathway is associated with cell apoptosis after non-alcoholic steatohepatitis. | 2018 | Details |
| A12379 | 30477455 | BMC Endocr Disord | Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial. | 2018 | Details |
| A12382 | 30476583 | Clin Gastroenterol Hepatol | Liver Fat Is Associated With Markers of Inflammation and Oxidative Stress in Analysis of Data From the Framingham Heart Study. | 2018 | Details |
| A12405 | 30469030 | Redox Biol | Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes. | 2018 | Details |
| A12414 | 30465824 | Free Radic Biol Med | Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia. | 2018 | Details |
| A12421 | 30460863 | Pharm Biol | Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus. | 2018 | Details |
| A12424 | 30459251 | Diabetes | Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12436 | 30455585 | Contemp Oncol (Pozn) | Update in global trends and aetiology of hepatocellular carcinoma. | 2018 | Details |
| A12437 | 30455376 | Diabetes | HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. | 2018 | Details |
| A12440 | 30454891 | Biochem Biophys Res Commun | Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress. | 2018 | Details |
| A12442 | 30454829 | Clin Liver Dis | Will Studies in Nonalcoholic Steatohepatitis Help Manage Alcoholic Steatohepatitis? | 2019 | Details |
| A12444 | 30454678 | Mutat Res Rev Mutat Res | Epigenetics: An emerging field in the pathogenesis of nonalcoholic fatty liver disease. | 2018 | Details |
| A12446 | 30453990 | J Transl Med | Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. | 2018 | Details |
| A12447 | 30453950 | BMC Complement Altern Med | Evaluation of the effect of Lactobacillus reuteri V3401 on biomarkers of inflammation, cardiovascular risk and liver steatosis in obese adults with metabolic syndrome: a randomized clinical trial (PROSIR). | 2018 | Details |
| A12450 | 30451987 | Eur J Clin Nutr | Diet with greater inflammatory potential is associated with higher prevalence of fatty liver among US adults. | 2018 | Details |
| A12458 | 30446932 | Hepatol Int | The effects of curcumin on the metabolic parameters of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2018 | Details |
| A12461 | 30445988 | Trials | Effect of a high-protein diet with β-cryptoxanthin supplementation on metabolic risk factors, oxidative and inflammatory biomarkers in non-alcoholic fatty liver disease (NAFLD): study protocol for a randomized controlled clinical trial. | 2018 | Details |
| A12471 | 30441981 | Vnitr Lek | Future of pharmacological treatment of non-alcoholic steatohepatitis in terms of key pathophysiological mechanisms. | 2019 | Details |
| A12474 | 30431378 | Curr Med Res Opin | Severe nonalcoholic steatohepatitis and type 2 diabetes: liver histology after weight loss therapy in a randomized clinical trial. | 2018 | Details |
| A12477 | 30430605 | Aliment Pharmacol Ther | Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non-alcoholic fatty liver disease. | 2018 | Details |
| A12482 | 30429827 | Front Endocrinol (Lausanne) | Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways. | 2018 | Details |
| A12488 | 30427909 | PLoS One | Non-alcoholic fatty liver disease in underweight patients with inflammatory bowel disease: A case-control study. | 2018 | Details |
| A12490 | 30425964 | Front Oncol | Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. | 2018 | Details |
| A12502 | 30417996 | Pak J Biol Sci | Comparative Study of Orange and its Main Bioactive Constituents as Remedy for Non-alcoholic Fatty Liver in Rats. | 2018 | Details |
| A12503 | 30416839 | Liver Res | Gut microbiota, fatty liver disease, and hepatocellular carcinoma. | 2018 | Details |
| A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |
| A12513 | 30413815 | Lab Invest | Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero. | 2018 | Details |
| A12517 | 30411763 | Food Funct | Hepatoprotective mechanism of freshwater clam extract alleviates non-alcoholic fatty liver disease: elucidated in vitro and in vivo models. | 2018 | Details |
| A12518 | 30411754 | Food Funct | Blueberry, combined with probiotics, alleviates non-alcoholic fatty liver disease via IL-22-mediated JAK1/STAT3/BAX signaling. | 2018 | Details |
| A12531 | 30408316 | Mol Nutr Food Res | Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver. | 2018 | Details |
| A12532 | 30405618 | Front Immunol | Adapted Immune Responses of Myeloid-Derived Cells in Fatty Liver Disease. | 2018 | Details |
| A12539 | 30402207 | Oxid Med Cell Longev | miR-26a Potentially Contributes to the Regulation of Fatty Acid and Sterol Metabolism In Vitro Human HepG2 Cell Model of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12540 | 30402130 | Evid Based Complement Alternat Med | Sheng-Jiang Powder Ameliorates High Fat Diet Induced Nonalcoholic Fatty Liver Disease via Inhibiting Activation of Akt/mTOR/S6 Pathway in Rats. | 2018 | Details |
| A12558 | 30392013 | J Gastroenterol | Antimicrobial proteins: intestinal guards to protect against liver disease. | 2018 | Details |
| A12560 | 30391126 | Trends Mol Med | Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism. | 2018 | Details |
| A12565 | 30388763 | Nutrients | Bergamot Polyphenols Boost Therapeutic Effects of the Diet on Non-Alcoholic Steatohepatitis (NASH) Induced by "Junk Food": Evidence for Anti-Inflammatory Activity. | 2018 | Details |
| A12570 | 30387131 | J Cell Physiol | Repression of TXNIP-NLRP3 axis restores intestinal barrier function via inhibition of myeloperoxidase activity and oxidative stress in nonalcoholic steatohepatitis. | 2018 | Details |
| A12576 | 30382148 | Sci Rep | Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model. | 2018 | Details |
| A12580 | 30379980 | Acta Biochim Biophys Sin (Shanghai) | Chronic intermittent hypoxia promotes the development of experimental non-alcoholic steatohepatitis by modulating Treg/Th17 differentiation. | 2018 | Details |
| A12582 | 30378562 | Biomed Khim | [Factors governing development of nonalcoholic fatty liver disease and insulin resistance in obesity]. | 2018 | Details |
| A12585 | 31949616 | Int J Clin Exp Pathol | N,N'-diacetylcystine ameliorates inflammation in experimental non-alcoholic steatohepatitis by regulating nuclear transcription factor kappa B activation. | 2018 | Details |
| A12592 | 30372785 | Hepatology | Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis. | 2019 | Details |
| A12594 | 30371253 | J Am Heart Assoc | Liver Disease as a Predictor of New-Onset Atrial Fibrillation. | 2018 | Details |
| A12595 | 30369883 | Front Physiol | Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity. | 2018 | Details |
| A12596 | 30369082 | J Diabetes Investig | Nicotinic alpha-7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2018 | Details |
| A12599 | 30368556 | Eur J Nutr | Differential capability of metabolic substrates to promote hepatocellular lipid accumulation. | 2018 | Details |
| A12606 | 30366981 | Mol Pharmacol | Cilostazol Improves HFD-Induced Hepatic Steatosis by Upregulating Hepatic STAMP2 Expression through AMPK. | 2018 | Details |
| A12619 | 30362092 | Adv Exp Med Biol | Chronic Ethanol Consumption and Generation of Etheno-DNA Adducts in Cancer-Prone Tissues. | 2019 | Details |
| A12628 | 30360437 | Int J Mol Sci | Dietary Isoliquiritigenin at a Low Dose Ameliorates Insulin Resistance and NAFLD in Diet-Induced Obesity in C57BL/6J Mice. | 2018 | Details |
| A12633 | 30358115 | Liver Transpl | Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. | 2019 | Details |
| A12635 | 30357769 | Semin Liver Dis | Unfolded Protein Response Sensors in Hepatic Lipid Metabolism and Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12638 | 30356113 | Sci Rep | Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis. | 2018 | Details |
| A12640 | 30355361 | Lipids Health Dis | Sleeve gastrectomy attenuates high fat diet-induced non-alcoholic fatty liver disease. | 2018 | Details |
| A12657 | 30343673 | Biol Sex Differ | Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. | 2018 | Details |
| A12658 | 30343320 | Cell Mol Life Sci | Molecular pathways of nonalcoholic fatty liver disease development and progression. | 2018 | Details |
| A12662 | 30340105 | Int Immunopharmacol | Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. | 2018 | Details |
| A12677 | 30333571 | Sci Rep | Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver. | 2018 | Details |
| A12682 | 30328907 | Acta Cir Bras | Oxidative stress on ischemia/reperfusion injury in mice with non-alcoholic hepatic steatosis or steatohepatitis. | 2018 | Details |
| A12683 | 30328321 | Yonsei Med J | S100A4 Gene is Crucial for Methionine-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. | 2018 | Details |
| A12698 | 30323247 | Sci Rep | RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr-/- mice. | 2018 | Details |
| A12702 | 30322964 | J Immunol | Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A12719 | 30316865 | EBioMedicine | Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice. | 2018 | Details |
| A12730 | 30314283 | Int J Mol Sci | CEACAM1 in Liver Injury, Metabolic and Immune Regulation. | 2018 | Details |
| A12745 | 30306412 | J Ultrasound | Contrast-enhanced ultrasound patterns of hepatocellular adenoma: an Italian multicenter experience. | 2018 | Details |
| A12750 | 30303744 | FASEB J | Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis. | 2018 | Details |
| A12756 | 30300287 | Transplantation | Nonalcoholic Fatty Liver Disease: Basic Pathogenetic Mechanisms in the Progression From NAFLD to NASH. | 2019 | Details |
| A12762 | 30298748 | Am J Chin Med | Beneficial Effects of Korean Red Ginseng in the Progression of Non-Alcoholic Steatohepatitis via FABP4 Modulation. | 2018 | Details |
| A12778 | 30292107 | J Nutr Biochem | Liraglutide modulates gut microbiota and reduces NAFLD in obese mice. | 2018 | Details |
| A12786 | 30288476 | Hepatol Commun | Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12789 | 30287733 | Nutrients | Achacha (Garcinia humilis) Rind Improves Cardiovascular Function in Rats with Diet-Induced Metabolic Syndrome. | 2018 | Details |
| A12812 | 30272851 | Asia Pac J Clin Nutr | Pro- and prebiotic effects on oxidative stress and inflammatory markers in non-alcoholic fatty liver disease. | 2019 | Details |
| A12823 | 30266576 | Diabetes Metab | Clinical and metabolic characterization of obese subjects without non-alcoholic fatty liver: A targeted metabolomics approach. | 2018 | Details |
| A12827 | 30266038 | Br J Pharmacol | Diethyldithiocarbamate, an anti-abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress. | 2018 | Details |
| A12831 | 30263038 | Nutr Metab (Lond) | Green cardamom increases Sirtuin-1 and reduces inflammation in overweight or obese patients with non-alcoholic fatty liver disease: a double-blind randomized placebo-controlled clinical trial. | 2018 | Details |
| A12832 | 30262993 | Int J Biol Sci | Polydatin attenuates diet-induced nonalcoholic steatohepatitis and fibrosis in mice. | 2018 | Details |