Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20508 | 25916635 | Biochim Biophys Acta | Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway. | 2015 | Details |
| A20511 | 25915484 | Curr Drug Targets | Antioxidant Mechanisms in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20526 | 25910362 | Turk J Gastroenterol | Advanced oxidation protein products, total thiol levels and total oxidant/antioxidant status in patients with nash. | 2014 | Details |
| A20535 | 25905791 | Food Funct | Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose. | 2015 | Details |
| A20544 | 25897647 | Crit Rev Food Sci Nutr | The potential of flavonoids in the treatment of non-alcoholic fatty liver disease. | 2017 | Details |
| A20552 | 25892859 | World J Gastroenterol | Nonalcoholic fatty liver disease, metabolic risk factors, and hepatocellular carcinoma: an open question. | 2015 | Details |
| A20560 | 25886887 | BMC Gastroenterol | Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. | 2015 | Details |
| A20585 | 25871295 | Mar Drugs | Anti-obesity activity of the marine carotenoid fucoxanthin. | 2015 | Details |
| A20596 | 25865685 | Hepatobiliary Pancreat Dis Int | Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. | 2015 | Details |
| A20610 | 25852263 | World J Gastroenterol | Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2015 | Details |
| A20619 | 25849376 | PLoS One | Proteomic analysis of mice fed methionine and choline deficient diet reveals marker proteins associated with steatohepatitis. | 2015 | Details |
| A20621 | 25848479 | World J Hepatol | Probiotics as a complementary therapeutic approach in nonalcoholic fatty liver disease. | 2015 | Details |
| A20632 | 25845417 | Liver Int | The association between the serum levels of uric acid and alanine aminotransferase in a population-based cohort. | 2015 | Details |
| A20637 | 25841776 | Free Radic Biol Med | Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. | 2015 | Details |
| A20642 | 25838034 | Metabolism | Endoplasmic Reticulum Stress Response in Non-alcoholic Steatohepatitis: The Possible Role of Physical Exercise. | 2015 | Details |
| A20647 | 25835554 | Int J Obes (Lond) | Heme oxygenase-1 gene promoter polymorphism and the risk of pediatric nonalcoholic fatty liver disease. | 2015 | Details |
| A20661 | 27308418 | Mol Cell Oncol | KEAP the balance between life and death. | 2014 | Details |
| A20666 | 25819147 | Orv Hetil | [Non-invasive assessment of fatty liver]. | 2015 | Details |
| A20672 | 25815106 | Oxid Med Cell Longev | P2X7 receptor as a key player in oxidative stress-driven cell fate in nonalcoholic steatohepatitis. | 2015 | Details |
| A20688 | 25798066 | Int J Biol Sci | Stem cell transplantation upregulates Sirt1 and antioxidant expression, ameliorating fatty liver in type 2 diabetic mice. | 2015 | Details |
| A20717 | 25780284 | World J Gastroenterol | Chemokine ligand 2 and paraoxonase-1 in non-alcoholic fatty liver disease: The search for alternative causative factors. | 2015 | Details |
| A20718 | 25777368 | Genes Cells | Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis. | 2015 | Details |
| A20730 | 25772634 | Eur J Nutr | Effects of red wine on postprandial stress: potential implication in non-alcoholic fatty liver disease development. | 2015 | Details |
| A20737 | 25767392 | Ther Clin Risk Manag | Therapeutic effect of hybrid training of voluntary and electrical muscle contractions in middle-aged obese women with nonalcoholic fatty liver disease: a pilot trial. | 2015 | Details |
| A20748 | 25757271 | Yao Xue Xue Bao | [Recent advances in curcumin and its derivatives for treatment of liver diseases]. | 2014 | Details |
| A20760 | 25751727 | Int J Mol Sci | Potential epigenetic mechanism in non-alcoholic Fatty liver disease. | 2015 | Details |
| A20799 | 25729475 | World J Hepatol | Recent advances in dietary supplementation, in treating non-alcoholic fatty liver disease. | 2015 | Details |
| A20816 | 25714891 | Braz J Med Biol Res | Sorafenib prevents liver fibrosis in a non-alcoholic steatohepatitis (NASH) rodent model. | 2015 | Details |
| A20822 | 25712622 | Mol Nutr Food Res | Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20827 | 25708949 | Naunyn Schmiedebergs Arch Pharmacol | Protective effect of boswellic acids versus pioglitazone in a rat model of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure. | 2015 | Details |
| A20841 | 25697114 | Med Hypotheses | Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. | 2015 | Details |
| A20878 | 25669689 | Physiol Res | Peroxisomal enzymes in the liver of rats with experimental diabetes mellitus type 2. | 2014 | Details |
| A20880 | 25668433 | PLoS Negl Trop Dis | Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders. | 2015 | Details |
| A20884 | 25665792 | Am J Pathol | Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. | 2015 | Details |
| A20890 | 25659874 | Atheroscler Suppl | The effect of ezetimibe on NAFLD. | 2015 | Details |
| A20917 | 25646700 | Liver Int | Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis. | 2015 | Details |
| A20927 | 25636888 | Phytomedicine | Two cinnamoyloctopamine antioxidants from garlic skin attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis. | 2014 | Details |
| A20936 | 25632182 | World J Gastroenterol | Novel insights into the mechanisms whereby isoflavones protect against fatty liver disease. | 2015 | Details |
| A20950 | 25621497 | J Clin Invest | Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease. | 2015 | Details |
| A20972 | 25609476 | Sci Rep | Potent effects of dioscin against obesity in mice. | 2015 | Details |
| A20985 | 25602171 | Antioxid Redox Signal | Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation. | 2015 | Details |
| A20986 | 25601465 | Curr Mol Med | Understanding nutritional interventions and physical exercise in non-alcoholic fatty liver disease. | 2015 | Details |
| A20995 | 25597144 | J Egypt Soc Parasitol | Pharmacological and antioxidant actions of garlic and.or onion in non-alcoholic fatty liver disease (NAFLD) in rats. | 2014 | Details |
| A21008 | 25581125 | Hepatol Res | Alleviation mechanisms against hepatocyte oxidative stress in patients with chronic hepatic disorders. | 2015 | Details |
| A21017 | 25575111 | Can J Gastroenterol Hepatol | Biomarkers in nonalcoholic fatty liver disease. | 2014 | Details |
| A21036 | 25563143 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease as a potential risk factor of cardiovascular disease. | 2015 | Details |
| A21038 | 25562318 | J Clin Invest | Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. | 2014 | Details |
| A21070 | 27051920 | Eksp Klin Farmakol | [EFFECTS OF MELATONIN ON THE ACONITATE HYDRATASE ACTIVITY, CONTENT OF LIPID PEROXIDATION PRODUCTS AND SOME NON-ENZYMATIC ANTIOXIDANTS IN THE BLOOD OF PATIENTS WITH TYPE 2 DIABETES MELLITUS COMPLICATED BY STEATOHEPATITIS]. | 2015 | Details |
| A21084 | 25544867 | Oxid Med Cell Longev | Dietary blueberry and bifidobacteria attenuate nonalcoholic fatty liver disease in rats by affecting SIRT1-mediated signaling pathway. | 2014 | Details |
| A21089 | 25542756 | Eur J Pharmacol | Ameliorative effect of nicorandil on high fat diet induced non-alcoholic fatty liver disease in rats. | 2014 | Details |
| A21091 | 25541279 | Prostaglandins Leukot Essent Fatty Acids | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. | 2014 | Details |
| A21093 | 25540128 | Dis Model Mech | In vitro treatment of HepG2 cells with saturated fatty acids reproduces mitochondrial dysfunction found in nonalcoholic steatohepatitis. | 2014 | Details |
| A21118 | 25530013 | Nutr Res | Blood redox status is associated with the likelihood of nonalcoholic fatty liver disease irrespectively of diet's total antioxidant capacity. | 2014 | Details |
| A21135 | 25523099 | Exp Mol Med | Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A21140 | 25520925 | Biomedicine (Taipei) | Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty liver. | 2014 | Details |
| A21143 | 25516477 | Metabolism | The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy. | 2014 | Details |
| A21172 | 25501551 | Am J Physiol Gastrointest Liver Physiol | Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. | 2014 | Details |
| A21179 | 25496866 | Zhonghua Gan Zang Bing Za Zhi | [Influence of GLP-1 on oxidative stress injury in non-alcoholic fatty liver disease rats]. | 2014 | Details |
| A21237 | 25462563 | Biochem Biophys Res Commun | The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD. | 2014 | Details |
| A21238 | 25462066 | Redox Biol | The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts. | 2014 | Details |
| A21248 | 25456789 | Med Hypotheses | Nonalcoholic fatty liver disease (NAFLD)--is it a new marker of hyporesponsiveness to recombinant human erythropoietin in patients that are on chronic hemodialysis? | 2014 | Details |
| A21254 | 25453980 | Peptides | The role of renin-angiotensin system modulation on treatment and prevention of liver diseases. | 2014 | Details |
| A21262 | 25450583 | Arch Med Res | Oral coenzyme Q10 supplementation in patients with nonalcoholic fatty liver disease: effects on serum vaspin, chemerin, pentraxin 3, insulin resistance and oxidative stress. | 2014 | Details |
| A21267 | 25446569 | Eur J Pharmacol | Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway. | 2014 | Details |
| A21272 | 25443620 | Liver Int | The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation. | 2015 | Details |
| A21293 | 25429318 | World J Hepatol | Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease. | 2014 | Details |
| A21320 | 25407526 | Int J Mol Sci | Plasma levels of homocysteine and cysteine increased in pediatric NAFLD and strongly correlated with severity of liver damage. | 2014 | Details |
| A21322 | 25406833 | J Transl Med | Hepatoprotective and antioxidant activities of extracts from Salvia-Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice. | 2014 | Details |
| A21333 | 25400436 | World J Gastroenterol | Gut-liver axis and probiotics: their role in non-alcoholic fatty liver disease. | 2014 | Details |
| A21339 | 25392542 | J Am Heart Assoc | Mitochondrial aldehyde dehydrogenase activation by Alda-1 inhibits atherosclerosis and attenuates hepatic steatosis in apolipoprotein E-knockout mice. | 2014 | Details |
| A21342 | 25389366 | Am J Physiol Endocrinol Metab | CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice. | 2014 | Details |
| A21352 | 25382334 | Chin Med J (Engl) | Expression and significance of fat mass and obesity associated gene and forkhead transcription factor O1 in non-alcoholic fatty liver disease. | 2014 | Details |
| A21389 | 25353663 | Nutrients | Effects of dietary fat and saturated fat content on liver fat and markers of oxidative stress in overweight/obese men and women under weight-stable conditions. | 2014 | Details |
| A21402 | 25347994 | J Pharmacol Exp Ther | M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. | 2014 | Details |
| A21413 | 25339808 | World J Gastroenterol | Non-alcoholic fatty liver disease: what has changed in the treatment since the beginning? | 2014 | Details |
| A21414 | 25339807 | World J Gastroenterol | Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease. | 2014 | Details |
| A21420 | 25332112 | Proteomics | Proteomic profile of carbonylated proteins in rat liver: discovering possible mechanisms for tetracycline-induced steatosis. | 2014 | Details |
| A21426 | 25328157 | Br J Nutr | Astaxanthin lowers plasma TAG concentrations and increases hepatic antioxidant gene expression in diet-induced obesity mice. | 2014 | Details |
| A21438 | 25317840 | Food Funct | Lactobacillus plantarum NCU116 improves liver function, oxidative stress and lipid metabolism in rats with high fat diet induced non-alcoholic fatty liver disease. | 2014 | Details |
| A21440 | 25317811 | Eur Rev Med Pharmacol Sci | Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). | 2014 | Details |
| A21441 | 25316683 | JPEN J Parenter Enteral Nutr | Branched-Chain Amino Acid-Rich Supplements Containing Microelements Have Antioxidant Effects on Nonalcoholic Steatohepatitis in Mice. | 2014 | Details |
| A21452 | 25310017 | Food Funct | Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats. | 2014 | Details |
| A21455 | 25309067 | World J Gastroenterol | Nonalcoholic fatty liver disease and vascular disease: state-of-the-art. | 2014 | Details |
| A21477 | 25294219 | Toxicol Sci | Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice. | 2014 | Details |
| A21479 | 25292174 | Obesity (Silver Spring) | Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression. | 2014 | Details |
| A21501 | 25271091 | Hepatology | Moderate to vigorous physical activity volume is an important factor for managing nonalcoholic fatty liver disease: a retrospective study. | 2015 | Details |
| A21506 | 25267960 | J Gastrointestin Liver Dis | A potential treatment of non-alcoholic fatty liver disease with SIRT1 activators. | 2014 | Details |
| A21513 | 25262992 | Eur J Intern Med | Serum homocysteine levels, oxidative stress and cardiovascular risk in non-alcoholic steatohepatitis. | 2014 | Details |
| A21515 | 25261569 | Dis Model Mech | High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A21545 | 25241023 | Eur J Nutr | The effect of tomato juice supplementation on biomarkers and gene expression related to lipid metabolism in rats with induced hepatic steatosis. | 2014 | Details |
| A21569 | 25220580 | Sleep Med Rev | Impact of obstructive sleep apnea treatment by continuous positive airway pressure on cardiometabolic biomarkers: a systematic review from sham CPAP randomized controlled trials. | 2014 | Details |
| A21590 | 25203315 | Hepatology | ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis. | 2015 | Details |
| A21595 | 25195642 | Nutrients | Epigenetic mechanisms underlying the link between non-alcoholic fatty liver diseases and nutrition. | 2014 | Details |
| A21615 | 25185415 | Clin Lab | The significance of serum xanthine oxidoreductase in patients with nonalcoholic fatty liver disease. | 2014 | Details |
| A21622 | 25180626 | Mol Med | Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-induced simple steatosis. | 2014 | Details |
| A21650 | 25152980 | Ann Hepatol | Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease. | 2015 | Details |
| A21652 | 25152587 | World J Gastroenterol | Noninvasive biomarkers in non-alcoholic fatty liver disease: current status and a glimpse of the future. | 2014 | Details |
| A21656 | 25145655 | Toxicol Sci | Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. | 2014 | Details |
| A21663 | 25140191 | Nutr Metab (Lond) | Effects and mechanisms of resveratrol on the amelioration of oxidative stress and hepatic steatosis in KKAy mice. | 2014 | Details |
| A21679 | 25126158 | Int J Clin Exp Med | Signal transductions and nonalcoholic fatty liver: a mini-review. | 2014 | Details |