Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Curcumin158 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19650 | 26436447 | Liver Int | Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives. | 2015 | Details |
| A20619 | 25849376 | PLoS One | Proteomic analysis of mice fed methionine and choline deficient diet reveals marker proteins associated with steatohepatitis. | 2015 | Details |
| A20748 | 25757271 | Yao Xue Xue Bao | [Recent advances in curcumin and its derivatives for treatment of liver diseases]. | 2014 | Details |
| A22489 | 24520264 | Exp Ther Med | Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohepatitis induced by a methionine- and choline-deficient diet. | 2013 | Details |
| A22792 | 24302567 | Mol Nutr Food Res | Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds. | 2013 | Details |
| A22921 | 24209497 | Lipids Health Dis | Nonalcoholic fatty liver disease: molecular pathways and therapeutic strategies. | 2013 | Details |
| A22979 | 24142602 | Eur Rev Med Pharmacol Sci | Curcumin decreases oleic acid-induced lipid accumulation via AMPK phosphorylation in hepatocarcinoma cells. | 2013 | Details |
| A23695 | 23558563 | Dig Dis Sci | Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes. | 2013 | Details |
| A24012 | 23303639 | Biofactors | Curcumin and liver disease. | 2013 | Details |
| A24555 | 22751848 | Int J Mol Med | Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis. | 2012 | Details |
| A24610 | 22692588 | Int J Mol Med | Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis. | 2012 | Details |
| A25243 | 22053378 | Zhonghua Gan Zang Bing Za Zhi | [The effects of curcumin derivative on experimental steatohepatitis]. | 2011 | Details |
| A26837 | 19681867 | Br J Pharmacol | Curcumin adds spice to the debate: lipid metabolism in liver disease. | 2009 | Details |
| A29175 | 34470535 | Hum Exp Toxicol | Effect of curcumin on the non-alcoholic steatohepatitis via inhibiting the M1 polarization of macrophages. | 2021 | Details |
| A32082 | 29234397 | Evid Based Complement Alternat Med | Artemisia iwayomogi plus Curcuma longa Synergistically Ameliorates Nonalcoholic Steatohepatitis in HepG2 Cells. | 2017 | Details |
| A33643 | 25532502 | Dig Dis Sci | Curcumin targets multiple pathways to halt hepatic stellate cell activation: updated mechanisms in vitro and in vivo. | 2014 | Details |
| A33696 | 25385666 | Ir J Med Sci | Liver injury attenuation by curcumin in a rat NASH model: an Nrf2 activation-mediated effect? | 2014 | Details |
| A34018 | 24614199 | Lab Invest | Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. | 2014 | Details |
| A35720 | 19841616 | Lab Invest | Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress. | 2009 | Details |
| A35768 | 19736547 | Lab Invest | Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. | 2009 | Details |
| A35865 | 19539747 | Free Radic Biol Med | Curcumin ameliorates rabbits's steatohepatitis via respiratory chain, oxidative stress, and TNF-alpha. | 2009 | Details |
| A35969 | 19299451 | Endocrinology | Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling. | 2009 | Details |
| A37182 | 19079906 | Nutr Res Rev | Therapeutic potential of curcumin in non-alcoholic steatohepatitis. | 2005 | Details |
| A42509 | 34331682 | Adv Exp Med Biol | Turmeric and Curcumin: From Traditional to Modern Medicine. | 2021 | Details |
| A43784 | 30888627 | Hepatol Int | Curcumin as a potential therapeutic option for NAFLD and other metabolic diseases: need for establishing the underlying mechanism(s) of action. | 2019 | Details |
| A43790 | 30879091 | Cell Mol Life Sci | Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases. | 2019 | Details |
| A45089 | 26108684 | Mol Nutr Food Res | Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling. | 2015 | Details |
| A46037 | 21472743 | Hepatology | Two solutions in search of a problem. | 2011 | Details |
| A47040 | 28476407 | Toxicol Appl Pharmacol | Curcumin improves alcoholic fatty liver by inhibiting fatty acid biosynthesis. | 2017 | Details |
| A47091 | 26305715 | IUBMB Life | Curcumin attenuates ethanol-induced hepatic steatosis through modulating Nrf2/FXR signaling in hepatocytes. | 2015 | Details |
| A47180 | 24063989 | Life Sci | Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK. | 2013 | Details |
| A47215 | 22538404 | Am J Physiol Gastrointest Liver Physiol | Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism. | 2012 | Details |
| A47276 | 19606259 | J Biomed Biotechnol | Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats. | 2009 | Details |
| A47364 | 12388178 | Am J Physiol Gastrointest Liver Physiol | Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. | 2002 | Details |
| A47614 | 35065811 | Life Sci | Corrigendum to "Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH)" [Life Sci. 285 (2021) 119983]. | 2022 | Details |
| A48176 | 20660066 | Endocrinology | Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids. | 2010 | Details |
| A48203 | 19901911 | Lab Invest | Curcumin limits the fibrogenic evolution of experimental steatohepatitis. | 2009 | Details |
| A48205 | 19808779 | Endocrinology | Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1. | 2009 | Details |
| A48567 | 33917706 | Pharmaceutics | Effect of Curcumin Nanoemulsions Stabilized with MAG and DAG-MCFAs in a Fructose-Induced Hepatic Steatosis Rat Model. | 2021 | Details |
| A48744 | 29966389 | Nutrients | Curcumin in Liver Diseases: A Systematic Review of the Cellular Mechanisms of Oxidative Stress and Clinical Perspective. | 2018 | Details |
| A48852 | 26609559 | Redox Biol | Curcumin inhibits activation of TRPM2 channels in rat hepatocytes. | 2015 | Details |
| A48978 | 22452372 | Br J Pharmacol | Curcumin ameliorates hepatic fibrosis in type 2 diabetes mellitus - insights into its mechanisms of action. | 2012 | Details |
| A48979 | 22449800 | Lab Invest | Curcumin eliminates the inhibitory effect of advanced glycation end-products (AGEs) on gene expression of AGE receptor-1 in hepatic stellate cells in vitro. | 2012 | Details |
| A48983 | 22352842 | Br J Pharmacol | Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress. | 2012 | Details |
| A49017 | 21195127 | Mol Cell Endocrinol | Curcumin diminishes the impacts of hyperglycemia on the activation of hepatic stellate cells by suppressing membrane translocation and gene expression of glucose transporter-2. | 2010 | Details |
| A49026 | 20977462 | Br J Pharmacol | Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase. | 2010 | Details |
| A49063 | 19594758 | Br J Pharmacol | Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells. | 2009 | Details |
| A49171 | 15582125 | J Hepatol | Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice. | 2004 | Details |
| A49418 | 35757255 | Front Nutr | Curcuminoids for Metabolic Syndrome: Meta-Analysis Evidences Toward Personalized Prevention and Treatment Management. | 2022 | Details |
| A49531 | 35723408 | Curr Issues Mol Biol | Validation of a Quantification Method for Curcumin Derivatives and Their Hepatoprotective Effects on Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49632 | 35684158 | Nutrients | 11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway. | 2022 | Details |
| A49713 | 35661765 | Complement Ther Med | Curcumin as adjuvant treatment in patients with non-alcoholic fatty liver (NAFLD) disease: A systematic review and meta-analysis. | 2022 | Details |
| A49844 | 35623903 | Phytother Res | Zingiberaceae plants/curcumin consumption and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of randomized controlled trials in humans. | 2022 | Details |
| A50225 | 35465117 | Prev Nutr Food Sci | Effect of Turmeric Supplementation on Blood Pressure and Serum Levels of Sirtuin 1 and Adiponectin in Patients with Nonalcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. | 2022 | Details |
| A50300 | 35438556 | J Med Food | Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α. | 2022 | Details |
| A50397 | 35405942 | Nutrients | Investigation of the Effect of Curcumin on Protein Targets in NAFLD Using Bioinformatic Analysis. | 2022 | Details |
| A50545 | 35345991 | Curr Pharm Des | The effects of curcumin supplementation on metabolic biomarkers and body mass index in patients with nonalcoholic fatty liver disease, a systematic review and meta-analysis of randomized controlled trials. | 2022 | Details |
| A52287 | 29115530 | Mol Med Rep | Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats. | 2017 | Details |