Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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DHA183 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19045 | 26805874 | Nutrients | Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes. | 2016 | Details |
| A19121 | 26748347 | Atherosclerosis | Improvement in non-alcoholic fatty liver disease severity is associated with a reduction in carotid intima-media thickness progression. | 2015 | Details |
| A19232 | 26683215 | Endocr Dev | Docosahexaenoic Acid and Its Role in G-Protein-Coupled Receptor 120 Activation in Children Affected by Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19249 | 26674248 | BBA Clin | Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy. | 2015 | Details |
| A19442 | 26567194 | Adv Nutr | Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer. | 2015 | Details |
| A19565 | 26482965 | Diabetes Metab Syndr | Gamma glutamyl transferase is an independent determinant for the association of insulin resistance with nonalcoholic fatty liver disease in Bangladeshi adults: Association of GGT and HOMA-IR with NAFLD. | 2015 | Details |
| A19589 | 26471014 | Food Funct | Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. | 2016 | Details |
| A19624 | 26449595 | J Agric Food Chem | Endocrine Disruptor DDE Associated with a High-Fat Diet Enhances the Impairment of Liver Fatty Acid Composition in Rats. | 2015 | Details |
| A19841 | 26315048 | J Lipid Res | Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway. | 2015 | Details |
| A19851 | 26307979 | Int J Mol Sci | Docosahexaenoic Acid Levels in Blood and Metabolic Syndrome in Obese Children: Is There a Link? | 2015 | Details |
| A19861 | 26300318 | Mol Nutr Food Res | Nonalcoholic fatty liver disease: Roles of the gut and the liver and metabolic modulation by some dietary factors and especially long-chain n-3 PUFA. | 2015 | Details |
| A19889 | 26282529 | Proc Nutr Soc | Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr-/- mice. | 2015 | Details |
| A19911 | 26272871 | J Hepatol | Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial. | 2015 | Details |
| A20042 | 26193881 | Lipids Health Dis | Eicosapentaenoic and docosahexaenoic acid-enriched high fat diet delays the development of fatty liver in mice. | 2015 | Details |
| A20175 | 26108973 | Eur J Clin Invest | Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD. | 2015 | Details |
| A20219 | 26078579 | World J Gastroenterol | Efficacy of poly-unsaturated fatty acid therapy on patients with nonalcoholic steatohepatitis. | 2015 | Details |
| A20280 | 26047766 | Clin Nutr | Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial. | 2015 | Details |
| A20331 | 26026214 | Nutr Metab Cardiovasc Dis | A double-blind, placebo-controlled randomized trial to evaluate the efficacy of docosahexaenoic acid supplementation on hepatic fat and associated cardiovascular risk factors in overweight children with nonalcoholic fatty liver disease. | 2015 | Details |
| A20341 | 26021488 | Diabetologia | Impact of high dose n-3 polyunsaturated fatty acid treatment on measures of microvascular function and vibration perception in non-alcoholic fatty liver disease: results from the randomised WELCOME trial. | 2015 | Details |
| A21058 | 29201676 | Euroasian J Hepatogastroenterol | Nonalcoholic Fatty Liver Disease: Study of Demographic and Predictive Factors. | 2015 | Details |
| A21791 | 25043514 | Hepatology | Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: results from the Welcome* study. | 2014 | Details |
| A21850 | 25003023 | FEBS Open Bio | Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis. | 2014 | Details |
| A21910 | 24967351 | Biomed Res Int | Enhanced amelioration of high-fat diet-induced fatty liver by docosahexaenoic acid and lysine supplementations. | 2014 | Details |
| A22078 | 24834820 | Environ Res | Secondhand tobacco exposure is associated with nonalcoholic fatty liver disease in children. | 2014 | Details |
| A22133 | 24796105 | Nihon Rinsho | [Liver diseases]. | 2014 | Details |
| A22156 | 24782632 | World J Gastroenterol | Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. | 2014 | Details |
| A22455 | 24556343 | Contemp Clin Trials | Design and rationale of the WELCOME trial: A randomised, placebo controlled study to test the efficacy of purified long chainomega-3 fatty acid treatment in non-alcoholic fatty liver disease [corrected]. | 2014 | Details |
| A22509 | 24505350 | PLoS One | Role of docosahexaenoic acid treatment in improving liver histology in pediatric nonalcoholic fatty liver disease. | 2014 | Details |
| A22530 | 24489722 | PLoS One | Cigarette smoke toxins deposited on surfaces: implications for human health. | 2014 | Details |
| A22539 | 24480733 | Arch Med Res | Time-dependent changes and association between liver free fatty acids, serum lipid profile and histological features in mice model of nonalcoholic fatty liver disease. | 2014 | Details |
| A22675 | 24322028 | Rom J Morphol Embryol | Effect of diet and omega-3 fatty acids in NAFLD. | 2013 | Details |
| A22719 | 24358308 | PLoS One | A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice. | 2013 | Details |
| A22761 | 24325457 | J Med Food | The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. | 2013 | Details |
| A22799 | 24295779 | Biochim Biophys Acta | Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice. | 2014 | Details |
| A22803 | 24292310 | Mymensingh Med J | Histological scoring and associated risk factors of non-alcoholic fatty liver disease. | 2013 | Details |
| A22804 | 24292291 | Mymensingh Med J | Risk factors of non-alcoholic fatty liver disease. | 2013 | Details |
| A22965 | 24167955 | Arch Latinoam Nutr | Prevention of liver steatosis through fish oil supplementation: correlation of oxidative stress with insulin resistance and liver fatty acid content. | 2013 | Details |
| A22981 | 24140006 | Prostaglandins Leukot Essent Fatty Acids | A diet high in α-linolenic acid and monounsaturated fatty acids attenuates hepatic steatosis and alters hepatic phospholipid fatty acid profile in diet-induced obese rats. | 2013 | Details |
| A23056 | 24074360 | J Med Food | The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-alcoholic fatty liver disease. | 2013 | Details |
| A23249 | 23928105 | Metabolism | Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. | 2013 | Details |
| A23536 | 23702094 | BMC Pediatr | Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial. | 2013 | Details |
| A24001 | 23313470 | Prostaglandins Leukot Essent Fatty Acids | Lipidomics of hepatic lipogenesis inhibition by omega 3 fatty acids. | 2013 | Details |
| A24011 | 23303872 | J Nutr | Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis. | 2013 | Details |
| A24112 | 23220074 | Nutr Metab Cardiovasc Dis | Docosahexaenoic acid for the treatment of fatty liver: randomised controlled trial in children. | 2012 | Details |
| A25018 | 22242926 | Metab Syndr Relat Disord | Docosahexaenoic acid prevents trans-10, cis-12-conjugated linoleic acid-induced nonalcoholic fatty liver disease in mice by altering expression of hepatic genes regulating fatty acid synthesis and oxidation. | 2012 | Details |
| A25213 | 22087354 | World J Diabetes | A defect in the activities of Δ and Δ desaturases and pro-resolution bioactive lipids in the pathobiology of non-alcoholic fatty liver disease. | 2011 | Details |
| A25903 | 21339799 | PLoS One | Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. | 2011 | Details |
| A25989 | 21233083 | Arch Dis Child | Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial. | 2011 | Details |
| A26301 | 20683463 | Eur J Clin Nutr | Intake of n-3 polyunsaturated fatty acids and non-alcoholic fatty liver disease: a cross-sectional study in Japanese men and women. | 2010 | Details |
| A26638 | 20042103 | Lipids Health Dis | Transgenic fat-1 mouse as a model to study the pathophysiology of cardiovascular, neurological and psychiatric disorders. | 2009 | Details |
| A27684 | 17671740 | Int J Mol Med | Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. | 2007 | Details |
| A27860 | 17228028 | Obesity (Silver Spring) | Polyunsaturated fatty acid pattern in liver and erythrocyte phospholipids from obese patients. | 2007 | Details |
| A28206 | 16142397 | Int J Mol Med | Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. | 2005 | Details |
| A28578 | 9407327 | J Gastroenterol Hepatol | Abnormality in fatty acid composition of gastric mucosal phospholipids in patients with liver cirrhosis and its correction with a polyunsaturated fatty acid-enriched soft oil capsule. | 1997 | Details |
| A28647 | 35189618 | Pharmacology | Docosahexaenoic Acid Attenuates the Progression of Nonalcoholic Steatohepatitis by Suppressing the Adipocyte Inflammation via the G Protein-Coupled Receptor 120/Free Fatty Acid Receptor 4 Pathway. | 2022 | Details |
| A28724 | 35092721 | J Control Release | Hepatic macrophage targeted siRNA lipid nanoparticles treat non-alcoholic steatohepatitis. | 2022 | Details |
| A30862 | 31655588 | BMC Health Serv Res | Implementation fidelity of village health and nutrition days in Hardoi District, Uttar Pradesh, India: a cross-sectional survey. | 2019 | Details |
| A34824 | 22515414 | Nutr Metab (Lond) | Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells. | 2012 | Details |
| A35453 | 20625232 | J Oleo Sci | Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis. | 2010 | Details |
| A42770 | 33525643 | Nutrients | The Marine Microalga, Tisochrysis lutea, Protects against Metabolic Disorders Associated with Metabolic Syndrome and Obesity. | 2021 | Details |
| A43671 | 31142011 | Int J Mol Sci | Involvement of G-Protein-Coupled Receptor 40 in the Inhibitory Effects of Docosahexaenoic Acid on SREBP1-Mediated Lipogenic Enzyme Expression in Primary Hepatocytes. | 2019 | Details |
| A43705 | 31076986 | Dig Dis Sci | Serum and Fecal Oxylipins in Patients with Alcohol-Related Liver Disease. | 2019 | Details |
| A44290 | 29142166 | J Toxicol Sci | Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling. | 2017 | Details |
| A44511 | 28409336 | Lipids | Dietary Docosahexaenoic Acid and trans-10, cis-12-Conjugated Linoleic Acid Differentially Alter Oxylipin Profiles in Mouse Periuterine Adipose Tissue. | 2017 | Details |
| A46985 | 31265202 | IUBMB Life | Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin-1 signaling. | 2019 | Details |
| A47185 | 23907024 | Food Chem Toxicol | A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes. | 2013 | Details |
| A49402 | 35762160 | Curr Opin Clin Nutr Metab Care | Omega-3 fatty acids and metabolic partitioning of fatty acids within the liver in the context of nonalcoholic fatty liver disease. | 2022 | Details |
| A50021 | 35561146 | Hepatology | Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD. | 2022 | Details |
| A50303 | 35438091 | Food Funct | Changes in the serum metabolomic profiles of subjects with NAFLD in response to n-3 PUFAs and phytosterol ester: a double-blind randomized controlled trial. | 2022 | Details |
| A50412 | 35400251 | Crit Rev Food Sci Nutr | Can omega-3 fatty acids be beneficial in pediatric NAFLD? A systematic review and meta-analysis. | 2022 | Details |
| A50564 | 35338970 | Bioorg Chem | Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress. | 2022 | Details |
| A50794 | 35263694 | Clin Nutr | Maternal polyunsaturated fatty acid concentrations during pregnancy and childhood liver fat accumulation. | 2022 | Details |
| A51597 | 35788956 | Hepatology | Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease. | 2022 | Details |
| A51725 | 34578953 | Nutrients | Maternal DHA Supplementation during Pregnancy and Lactation in the Rat Protects the Offspring against High-Calorie Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A52303 | 28888048 | J Cell Physiol | Involvement of nutrients and nutritional mediators in mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene expression. | 2017 | Details |
| A52455 | 26964726 | Obes Res Clin Pract | Predictive value of serum dihomo-γ-linolenic acid level and estimated Δ-5 desaturase activity in patients with hepatic steatosis. | 2016 | Details |
| A52550 | 25694146 | Anal Bioanal Chem | Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry (TOF-SIMS). | 2015 | Details |
| A52731 | 22701720 | PLoS One | Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. | 2012 | Details |
| A52866 | 20487553 | BMC Gastroenterol | Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis. | 2010 | Details |
| A52917 | 19549757 | J Nutr | Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. | 2009 | Details |
| A52946 | 19148125 | Obesity (Silver Spring) | Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. | 2009 | Details |
| A53031 | 16996649 | Neurobiol Aging | A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease. | 2006 | Details |
| A53062 | 16163656 | Rev Neurol | [Hypoglycaemia without ketosis. A case report]. | 2005 | Details |