Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00810 | 34959259 | FASEB J | High-fat diet-induced increases in glucocorticoids contribute to the development of non-alcoholic fatty liver disease in mice. | 2022 | Details |
| A00811 | 34959119 | Biomed Pharmacother | GDF-15, a future therapeutic target of glucolipid metabolic disorders and cardiovascular disease. | 2021 | Details |
| A00817 | 34957917 | Adipocyte | Adipose tissue plays a major role in retinoic acid-mediated metabolic homoeostasis. | 2022 | Details |
| A00846 | 34950107 | Front Endocrinol (Lausanne) | Analysis of N6-Methyladenosine Methylation Modification in Fructose-Induced Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00851 | 34948020 | Int J Mol Sci | The New Therapeutic Approaches in the Treatment of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00854 | 34945677 | Foods | Lactobacillus plantarum MA2 Ameliorates Methionine and Choline-Deficient Diet Induced Non-Alcoholic Fatty Liver Disease in Rats by Improving the Intestinal Microecology and Mucosal Barrier. | 2021 | Details |
| A00855 | 34945573 | Foods | The Regulatory Effects of Citrus Peel Powder on Liver Metabolites and Gut Flora in Mice with Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A00859 | 34944732 | Biomedicines | Therapeutic Opportunities of IL-22 in Non-Alcoholic Fatty Liver Disease: From Molecular Mechanisms to Clinical Applications. | 2021 | Details |
| A00861 | 34944728 | Biomedicines | Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism. | 2021 | Details |
| A00871 | 34944021 | Cells | IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism. | 2021 | Details |
| A00875 | 34943814 | Cells | Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2. | 2021 | Details |
| A00884 | 34942286 | J Hepatol | Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease. | 2021 | Details |
| A00888 | 34940698 | Mar Drugs | Soluble Polysaccharide Derived from Laminaria japonica Attenuates Obesity-Related Nonalcoholic Fatty Liver Disease Associated with Gut Microbiota Regulation. | 2021 | Details |
| A00914 | 34931979 | Curr Mol Med | Endogenous liver protections against lipotoxicity and oxidative stress to avoid the progression of non-alcoholic fatty liver to more serious disease. | 2022 | Details |
| A00916 | 34931080 | Nat Metab | Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity. | 2021 | Details |
| A00926 | 34927282 | Drug Dev Res | Schisandrin B ameliorates non-alcoholic liver disease through anti-inflammation activation in diabetic mice. | 2021 | Details |
| A00937 | 34923965 | BMC Gastroenterol | Comparison of several blood lipid-related indexes in the screening of non-alcoholic fatty liver disease in women: a cross-sectional study in the Pearl River Delta region of southern China. | 2021 | Details |
| A00943 | 34923087 | J Ethnopharmacol | Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters. | 2021 | Details |
| A00947 | 34922572 | Nutr Metab (Lond) | Alleviating the effect of quinoa and the underlying mechanism on hepatic steatosis in high-fat diet-fed rats. | 2021 | Details |
| A00955 | 34920070 | Int J Biol Macromol | MDG, an Ophiopogon japonicus polysaccharide, inhibits non-alcoholic fatty liver disease by regulating the abundance of Akkermansia muciniphila. | 2021 | Details |
| A00973 | 34914973 | Exp Mol Pathol | TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop. | 2021 | Details |
| A00980 | 34911556 | BMC Biol | Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress. | 2021 | Details |
| A01000 | 34906049 | Biochemistry (Mosc) | AMPK/PGC-1α/GLUT4-Mediated Effect of Icariin on Hyperlipidemia-Induced Non-Alcoholic Fatty Liver Disease and Lipid Metabolism Disorder in Mice. | 2021 | Details |
| A01006 | 34904613 | Food Funct | Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin. | 2022 | Details |
| A01014 | 34903883 | Nat Metab | Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis. | 2021 | Details |
| A01016 | 34902629 | Cell Mol Gastroenterol Hepatol | Escherichia fergusonii Promotes Nonobese Nonalcoholic Fatty Liver Disease by Interfering With Host Hepatic Lipid Metabolism Through Its Own msRNA 23487. | 2021 | Details |
| A01021 | 34901163 | Front Mol Biosci | The Role of Notch Signaling Pathway in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01024 | 34900534 | Acta Pharm Sin B | Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease. | 2021 | Details |
| A01026 | 34899591 | Front Endocrinol (Lausanne) | Varied Relationship of Lipid and Lipoprotein Profiles to Liver Fat Content in Phenotypes of Metabolic Associated Fatty Liver Disease. | 2021 | Details |
| A01027 | 34899351 | Front Pharmacol | Network Pharmacology-Based Analysis of Pogostemon cablin (Blanco) Benth Beneficial Effects to Alleviate Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A01034 | 34895322 | Stem Cell Res Ther | Bone marrow derived-mesenchymal stem cell improves diabetes-associated fatty liver via mitochondria transformation in mice. | 2021 | Details |
| A01054 | 34886991 | J Comp Pathol | Role of Plin5 Deficiency in Progression of Non-Alcoholic Fatty Liver Disease Induced by a High-Fat Diet in Mice. | 2021 | Details |
| A01056 | 34884968 | Int J Mol Sci | Neochlorogenic Acid Attenuates Hepatic Lipid Accumulation and Inflammation via Regulating miR-34a In Vitro. | 2021 | Details |
| A01057 | 34884910 | Int J Mol Sci | TG68, a Novel Thyroid Hormone Receptor-β Agonist for the Treatment of NAFLD. | 2021 | Details |
| A01061 | 34884625 | Int J Mol Sci | Hypothyroidism-Associated Dyslipidemia: Potential Molecular Mechanisms Leading to NAFLD. | 2021 | Details |
| A01062 | 34884447 | Int J Mol Sci | Intracellular Exposure Dose-Associated Susceptibility of Steatotic Hepatocytes to Metallic Nanoparticles. | 2021 | Details |
| A01064 | 34883038 | J Med Food | Hepatic Proteomics Analysis of Nonalcoholic Fatty Liver Disease Obese Rat Model After Short- and Long-Term Soy Protein Isolate Feeding. | 2021 | Details |
| A01068 | 34881283 | Front Nutr | Caffeine and EGCG Alleviate High-Trans Fatty Acid and High-Carbohydrate Diet-Induced NASH in Mice: Commonality and Specificity. | 2021 | Details |
| A01069 | 34880774 | Front Physiol | Effect of Long-Term Exercise on Liver Lipid Metabolism in Chinese Patients With NAFLD: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A01072 | 34878523 | Endocrinology | Adipose-specific VDR Deletion Leads to Hepatic Steatosis in Female Mice Fed a Low-Fat Diet. | 2022 | Details |
| A01095 | 34870551 | Pharm Biol | Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK. | 2022 | Details |
| A01109 | 34867343 | Front Pharmacol | Polygoni Multiflori Radix Praeparata Ethanol Extract Exerts a Protective Effect Against High-Fat Diet Induced Non-Alcoholic Fatty Liver Disease in Mice by Remodeling Intestinal Microbial Structure and Maintaining Metabolic Homeostasis of Bile Acids. | 2021 | Details |
| A01125 | 34862599 | Br J Pharmacol | Amlodipine, an anti-hypertensive drug, alleviates non-alcoholic fatty liver disease by modulating gut microbiota. | 2022 | Details |
| A01134 | 34859513 | Phytother Res | Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway. | 2021 | Details |
| A01150 | 34853966 | Bull Exp Biol Med | Knockdown of Sirt1 Gene in Mice Results in Lipid Accumulation in the Liver Mediated via PGC-1α-Induced Mitochondrial Dysfunction and Oxidative Stress. | 2021 | Details |
| A01154 | 34850865 | Dis Model Mech | Concerted regulation of non-alcoholic fatty liver disease progression by microRNAs in apolipoprotein E-deficient mice. | 2021 | Details |
| A01159 | 34848984 | Diabetes Metab Syndr Obes | Effect of LncPVT1/miR-20a-5p on Lipid Metabolism and Insulin Resistance in NAFLD. | 2021 | Details |
| A01160 | 34848839 | Exp Mol Med | Roles of IκB kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease. | 2021 | Details |
| A01161 | 34848360 | J Ethnopharmacol | Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. | 2021 | Details |
| A01185 | 34836315 | Nutrients | Network Pharmacology Exploration Reveals Anti-Apoptosis as a Common Therapeutic Mechanism for Non-Alcoholic Fatty Liver Disease Treated with Blueberry Leaf Polyphenols. | 2021 | Details |
| A01188 | 34835949 | Nutrients | Effects of Lingonberry (Vaccinium vitis-idaea L.) Supplementation on Hepatic Gene Expression in High-Fat Diet Fed Mice. | 2021 | Details |
| A01194 | 34831201 | Cells | Lipid Metabolism Disorders in the Comorbid Course of Nonalcoholic Fatty Liver Disease and Chronic Obstructive Pulmonary Disease. | 2021 | Details |
| A01198 | 34830360 | Int J Mol Sci | Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD. | 2021 | Details |
| A01203 | 34829889 | Biomedicines | Role of Ferroptosis in Non-Alcoholic Fatty Liver Disease and Its Implications for Therapeutic Strategies. | 2021 | Details |
| A01205 | 34829865 | Biomedicines | Machine Learning-Based Identification of Potentially Novel Non-Alcoholic Fatty Liver Disease Biomarkers. | 2021 | Details |
| A01214 | 34827721 | Biomolecules | The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01225 | 34822586 | Toxins (Basel) | Ochratoxin A Induces Steatosis via PPARγ-CD36 Axis. | 2021 | Details |
| A01245 | 34815444 | Sci Rep | A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates. | 2021 | Details |
| A01249 | 34814397 | Zhonghua Gan Zang Bing Za Zhi | [Study of abnormal lipid metabolism analysis and significance of fatty acid binding protein expression in patients with hepatocellular carcinoma]. | 2021 | Details |
| A01259 | 34811857 | Aging Cell | Cisd2 slows down liver aging and attenuates age-related metabolic dysfunction in male mice. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01281 | 34803499 | Int J Biol Sci | CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD+/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes. | 2021 | Details |
| A01300 | 34796193 | Front Nutr | Translatomics Probes Into the Role of Lycopene on Improving Hepatic Steatosis Induced by High-Fat Diet. | 2021 | Details |
| A01308 | 34794234 | Biomed Pharmacother | Saroglitazar and Hepano treatment offers protection against high fat high fructose diet induced obesity, insulin resistance and steatosis by modulating various class of hepatic and circulating lipids. | 2021 | Details |
| A01316 | 34789275 | J Nanobiotechnology | A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis. | 2021 | Details |
| A01324 | 34786857 | Mol Nutr Food Res | Oxidized Pork Induces Hepatic Steatosis by Impairing Thyroid Hormone Function in Mice. | 2021 | Details |
| A01352 | 34778099 | Front Cell Infect Microbiol | Gut Microbiota, Glucose, Lipid, and Water-Electrolyte Metabolism in Children With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01365 | 34774104 | Trials | Effects of naringenin supplementation in overweight/obese patients with non-alcoholic fatty liver disease: study protocol for a randomized double-blind clinical trial. | 2021 | Details |
| A01369 | 34773093 | Eur J Clin Nutr | Role of high-salt diet in non-alcoholic fatty liver disease: a mini-review of the evidence. | 2021 | Details |
| A01374 | 34769488 | Int J Mol Sci | The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases. | 2021 | Details |
| A01378 | 34768942 | Int J Mol Sci | In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia. | 2021 | Details |
| A01402 | 34759011 | Drug Metab Dispos | Environmental Chemical Contribution to the Modulation of Bile Acid Homeostasis and Farnesoid X Receptor Signaling. | 2021 | Details |
| A01416 | 34755918 | Environ Toxicol | Polystyrene nanoplastics potentiate the development of hepatic fibrosis in high fat diet fed mice. | 2021 | Details |
| A01432 | 34749473 | Zhonghua Yu Fang Yi Xue Za Zhi | [Effects of (+)-catechin and epigallocatechin gallate on alcoholic fatty liver in mice models]. | 2021 | Details |
| A01435 | 34746842 | Curr Res Physiol | High-fat diet-associated cognitive decline: Is zinc finger protein 1 (ZPR1) the molecular connection? | 2021 | Details |
| A01437 | 34746195 | Front Med (Lausanne) | Liver Fibrosis and MAFLD: From Molecular Aspects to Novel Pharmacological Strategies. | 2021 | Details |
| A01441 | 34745420 | Oxid Med Cell Longev | The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD. | 2021 | Details |
| A01466 | 34737121 | J Mol Cell Cardiol | NAFLD as a continuous driver in the whole spectrum of vascular disease. | 2021 | Details |
| A01476 | 34734090 | J Immunol Res | Mangiferin Ameliorates HFD-Induced NAFLD through Regulation of the AMPK and NLRP3 Inflammasome Signal Pathways. | 2021 | Details |
| A01479 | 34732369 | Pharmacol Res | Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease. | 2021 | Details |
| A01485 | 34728268 | Presse Med | Complications of lipodystrophy syndromes. | 2021 | Details |
| A01488 | 34727379 | Biomed Chromatogr | Lipidomic-based investigation into the therapeutic effects of polyene phosphatidylcholine and Babao Dan on rats with non-alcoholic fatty liver disease. | 2021 | Details |
| A01492 | 34726148 | Proc Nutr Soc | Dysregulation of hepatic metabolism with obesity: factors influencing glucose and lipid metabolism. | 2021 | Details |
| A01498 | 34722615 | Front Nutr | Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice. | 2021 | Details |
| A01523 | 34708234 | Sheng Li Xue Bao | [KLF9 regulates hepatic lipid metabolism via inducing CD36 expression]. | 2021 | Details |
| A01524 | 34708231 | Sheng Li Xue Bao | [The role of SIRT6 in nonalcoholic steatohepatitis]. | 2021 | Details |
| A01525 | 34708066 | Front Nutr | Integrated Transcriptomic and Translatomic Inquiry of the Role of Betaine on Lipid Metabolic Dysregulation Induced by a High-Fat Diet. | 2021 | Details |
| A01530 | 34707570 | Front Endocrinol (Lausanne) | Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter-Organ Crosstalk. | 2021 | Details |
| A01537 | 34706542 | J Agric Food Chem | Sulforaphane Regulates Glucose and Lipid Metabolisms in Obese Mice by Restraining JNK and Activating Insulin and FGF21 Signal Pathways. | 2021 | Details |
| A01553 | 34696656 | Xenobiotica | Transcription profiling of cadmium-exposed livers reveals alteration of lipid metabolism and predisposition to hepatic steatosis. | 2021 | Details |
| A01554 | 34695558 | J Nutr Biochem | Nobiletin mitigates hepatocytes death, liver inflammation, and fibrosis in a murine model of NASH through modulating hepatic oxidative stress and mitochondrial dysfunction. | 2021 | Details |
| A01555 | 34695228 | Eur J Clin Invest | Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis. | 2021 | Details |
| A01565 | 34691178 | J Oncol | Main Risk Factors of Type 2 Diabetes Mellitus with Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma. | 2021 | Details |
| A01579 | 34686466 | J Integr Med | Berberine mitigates nonalcoholic hepatic steatosis by downregulating SIRT1-FoxO1-SREBP2 pathway for cholesterol synthesis. | 2021 | Details |
| A01581 | 34685636 | Cells | Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality. | 2021 | Details |
| A01587 | 34684533 | Nutrients | Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice. | 2021 | Details |
| A01590 | 34684455 | Nutrients | Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model. | 2021 | Details |
| A01594 | 34684335 | Nutrients | Pathway Preferential Estrogens Prevent Hepatosteatosis Due to Ovariectomy and High-Fat Diets. | 2021 | Details |
| A01602 | 34681600 | Int J Mol Sci | Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling. | 2021 | Details |
| A01603 | 34681291 | Foods | Tebuconazole Fungicide Induces Lipid Accumulation and Oxidative Stress in HepG2 Cells. | 2021 | Details |