Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Nicotinamide170 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23201 | 23964925 | Genet Test Mol Biomarkers | Association of nicotinamide-N-methyltransferase gene rs694539 variant with patients with nonalcoholic steatohepatitis. | 2013 | Details |
| A23400 | 23813132 | Ann Hepatol | Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. | 2013 | Details |
| A23531 | 23703665 | Hepatology | Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice. | 2013 | Details |
| A23820 | 23447513 | Pediatr Obes | Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children. | 2013 | Details |
| A24156 | 23174488 | Clin Biochem | Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease. | 2012 | Details |
| A24235 | 23091808 | Clin Mol Hepatol | Enhanced A-FABP expression in visceral fat: potential contributor to the progression of NASH. | 2012 | Details |
| A24681 | 22613376 | Zhonghua Liu Xing Bing Xue Za Zhi | [Relationship between serum visfatin level and children and adolescent obesity and non-alcoholic fatty liver disease]. | 2012 | Details |
| A24817 | 22467327 | J Clin Lab Anal | Visfatin levels in nonalcoholic fatty liver disease. | 2012 | Details |
| A25688 | 21543212 | J Nutr Biochem | Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes. | 2011 | Details |
| A25996 | 21225497 | Pol J Pathol | Liver visfatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery. | 2010 | Details |
| A26290 | 20720266 | Ann Hepatol | Visceral adipose tissue visfatin in nonalcoholic fatty liver disease. | 2010 | Details |
| A26317 | 20656836 | Radiology | Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling. | 2010 | Details |
| A26322 | 20651844 | Biochem Cell Biol | Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. | 2010 | Details |
| A26331 | 20642104 | Pol Merkur Lekarski | [Evaluation of serum visfatin concentrations in children with nonalcoholic fatty liver disease]. | 2010 | Details |
| A26496 | 20392873 | J Clin Endocrinol Metab | Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease. | 2010 | Details |
| A26520 | 20370672 | Curr Pharm Des | Pre-B cell colony enhancing factor/NAMPT/visfatin in inflammation and obesity-related disorders. | 2010 | Details |
| A26848 | 19664840 | J Hepatol | Effects of weight loss induced by bariatric surgery on hepatic adipocytokine expression. | 2009 | Details |
| A27196 | 19005759 | Dig Dis Sci | Influence of visfatin on histopathological changes of non-alcoholic fatty liver disease. | 2008 | Details |
| A27551 | 18081738 | Aliment Pharmacol Ther | Adipokines and cytokines in non-alcoholic fatty liver disease. | 2007 | Details |
| A33490 | 25888330 | Gastroenterology | Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. | 2015 | Details |
| A33670 | 25461268 | Nitric Oxide | Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes. | 2014 | Details |
| A42495 | 34378991 | Am J Physiol Cell Physiol | Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes. | 2021 | Details |
| A42548 | 34183378 | Drug Metab Dispos | Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A42767 | 33529671 | J Hepatol | Reply to: "NNMT aggravates hepatic steatosis but alleviates liver injury in alcoholic liver disease" and "Two sides of NNMT in alcoholic and non-alcoholic fatty liver development". | 2021 | Details |
| A42832 | 33340570 | J Hepatol | Two sides of NNMT in alcoholic and non-alcoholic fatty liver development. | 2020 | Details |
| A43636 | 31240235 | Hypoxia (Auckl) | Role of pseudohypoxia in the pathogenesis of type 2 diabetes. | 2019 | Details |
| A44241 | 29264533 | J Endocr Soc | Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule. | 2017 | Details |
| A44530 | 28333140 | Cell Death Dis | Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase. | 2017 | Details |
| A44678 | 27435327 | Dig Dis Sci | Targeting Hepatic Fibrosis in Autoimmune Hepatitis. | 2016 | Details |
| A44942 | 26661503 | Hepatology | Therapeutic potential of nicotinamide adenine dinucleotide for nonalcoholic fatty liver disease. | 2016 | Details |
| A45037 | 26352206 | Biochim Biophys Acta | Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation. | 2015 | Details |
| A45479 | 24378279 | Ann Hepatol | Serum visfatin in nonalcoholic fatty liver disease. | 2014 | Details |
| A45757 | 22921094 | Am J Obstet Gynecol | Nutrient sensor-mediated programmed nonalcoholic fatty liver disease in low birthweight offspring. | 2012 | Details |
| A45879 | 22227071 | Nutr Metab Cardiovasc Dis | Lower plasma NAMPT/visfatin levels are associated with impaired hepatic mitochondrial function in non-diabetic obese women: a potential link between obesity and non-alcoholic fatty liver disease. | 2012 | Details |
| A46015 | 21538633 | NMR Biomed | Ursodeoxycholic acid treatment of hepatic steatosis: a (13)C NMR metabolic study. | 2011 | Details |
| A46310 | 19585655 | Hepatology | Adipokines in liver diseases. | 2009 | Details |
| A46333 | 19474719 | Curr Opin Clin Nutr Metab Care | Metabolic benefits from Sirt1 and Sirt1 activators. | 2009 | Details |
| A46493 | 18277391 | Obesity (Silver Spring) | Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance. | 2008 | Details |
| A46912 | 34525389 | J Nutr Biochem | A mouse model of the regression of alcoholic hepatitis: Monitoring the regression of hepatic steatosis, inflammation, oxidative stress, and NAD+ metabolism upon alcohol withdrawal. | 2021 | Details |
| A46942 | 33340581 | J Hepatol | NNMT aggravates hepatic steatosis, but alleviates liver injury in alcoholic liver disease. | 2020 | Details |
| A46984 | 31295533 | J Hepatol | The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice. | 2019 | Details |
| A47001 | 30721374 | Cell Biol Toxicol | Activation of SIRT1 by L-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes. | 2019 | Details |
| A47019 | 29457836 | Hepatology | DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease. | 2018 | Details |
| A47021 | 29368944 | Am J Physiol Gastrointest Liver Physiol | A specific amino acid formula prevents alcoholic liver disease in rodents. | 2018 | Details |
| A47027 | 29317476 | J Pharmacol Exp Ther | Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Attenuated Hepatic Triglyceride Accumulation in Alcoholic Fatty Liver Disease in Mice. | 2018 | Details |
| A47172 | 24262277 | Gastroenterology | Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver. | 2013 | Details |
| A47212 | 22684045 | Gastroenterology | β-Catenin regulates hepatic mitochondrial function and energy balance in mice. | 2012 | Details |
| A47290 | 19003881 | Hepatology | Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms. | 2008 | Details |
| A47467 | 1770192 | J Am Coll Nutr | Alcohol, liver, and nutrition. | 1991 | Details |
| A48019 | 26436133 | Adv Hepatol | NADPH Oxidases in Chronic Liver Diseases. | 2014 | Details |
| A48631 | 32651404 | Sci Rep | Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects. | 2020 | Details |
| A48672 | 31823815 | Hum Genomics | Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. | 2019 | Details |
| A48951 | 23388073 | Lipids Health Dis | Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. | 2013 | Details |
| A49076 | 18925608 | Hepatology | Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism. | 2008 | Details |
| A49415 | 35758365 | Medicine (Baltimore) | CONSORT-Characteristics and metabolic phenotype of gut microbiota in NAFLD patients. | 2022 | Details |
| A49848 | 35621963 | Mar Drugs | Monkfish Peptides Mitigate High Fat Diet-Induced Hepatic Steatosis in Mice. | 2022 | Details |
| A49858 | 35616339 | J Cell Physiol | The Clock-NAD+ -Sirtuin connection in nonalcoholic fatty liver disease. | 2022 | Details |
| A50172 | 35491150 | Yakugaku Zasshi | [Metabolism-dependent Vascular Pathophysiology in Adult Diseases]. | 2022 | Details |
| A50320 | 35434600 | Food Chem X | Kombucha - An ancient fermented beverage with desired bioactivities: A narrowed review. | 2022 | Details |
| A50603 | 35328352 | Int J Mol Sci | Beneficial Effects of Dietary Nitrite on a Model of Nonalcoholic Steatohepatitis Induced by High-Fat/High-Cholesterol Diets in SHRSP5/Dmcr Rats: A Preliminary Study. | 2022 | Details |
| A51851 | 33680863 | Toxicol Rep | Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy. | 2021 | Details |
| A52070 | 31676443 | Biochim Biophys Acta Mol Cell Biol Lipids | Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats. | 2019 | Details |
| A52263 | 29514072 | Cell Metab | Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. | 2018 | Details |
| A52409 | 27427417 | Am J Pathol | The Detrimental Role Played by Lipocalin-2 in Alcoholic Fatty Liver in Mice. | 2016 | Details |
| A52466 | 26742069 | Nutrients | Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats. | 2016 | Details |
| A52640 | 24307792 | World J Gastroenterol | Splanchnic-aortic inflammatory axis in experimental portal hypertension. | 2013 | Details |
| A52650 | 24184811 | Gastroenterology | Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21. | 2013 | Details |
| A52665 | 23954796 | J Am Heart Assoc | Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction. | 2013 | Details |
| A52883 | 20106640 | Nutr Metab Cardiovasc Dis | Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity. | 2010 | Details |
| A52920 | 19526498 | Magn Reson Med | In vivo measurement of ethanol metabolism in the rat liver using magnetic resonance spectroscopy of hyperpolarized [1-13C]pyruvate. | 2009 | Details |