Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01219 | 34825068 | Biochem Biophys Rep | Metformin treatment reverses high fat diet- induced non-alcoholic fatty liver diseases and dyslipidemia by stimulating multiple antioxidant and anti-inflammatory pathways. | 2021 | Details |
| A01221 | 34823063 | Cell Mol Gastroenterol Hepatol | TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models. | 2021 | Details |
| A01224 | 34822647 | Vet Sci | Protective and Therapeutic Effects of Orlistat on Metabolic Syndrome and Oxidative Stress in High-Fat Diet-Induced Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) in Rats: Role on Nrf2 Activation. | 2021 | Details |
| A01233 | 34819792 | Saudi Pharm J | Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease. | 2021 | Details |
| A01259 | 34811857 | Aging Cell | Cisd2 slows down liver aging and attenuates age-related metabolic dysfunction in male mice. | 2021 | Details |
| A01260 | 34811578 | Handb Exp Pharmacol | NAFLD and NASH: The Metabolically Diseased Liver. | 2021 | Details |
| A01262 | 34810376 | Saudi J Gastroenterol | Nonalcoholic fatty liver disease: The role of quercetin and its therapeutic implications. | 2022 | Details |
| A01269 | 34808388 | Bioorg Med Chem Lett | Design, synthesis and activity evaluation of prodrug form JBP485 and Vitamin E for alleviation of NASH. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01279 | 34803916 | Front Endocrinol (Lausanne) | Sestrin2 as a Potential Target for Regulating Metabolic-Related Diseases. | 2021 | Details |
| A01281 | 34803499 | Int J Biol Sci | CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD+/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes. | 2021 | Details |
| A01324 | 34786857 | Mol Nutr Food Res | Oxidized Pork Induces Hepatic Steatosis by Impairing Thyroid Hormone Function in Mice. | 2021 | Details |
| A01339 | 34783554 | J Agric Food Chem | Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition. | 2021 | Details |
| A01342 | 34783017 | Br J Pharmacol | A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation. | 2022 | Details |
| A01343 | 34781143 | Biomed Pharmacother | Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction. | 2021 | Details |
| A01365 | 34774104 | Trials | Effects of naringenin supplementation in overweight/obese patients with non-alcoholic fatty liver disease: study protocol for a randomized double-blind clinical trial. | 2021 | Details |
| A01373 | 34771023 | Molecules | Zinc as a Drug for Wilson's Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver Injury. | 2021 | Details |
| A01378 | 34768942 | Int J Mol Sci | In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia. | 2021 | Details |
| A01385 | 34765085 | Oxid Med Cell Longev | Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function. | 2021 | Details |
| A01411 | 34757160 | Toxicology | The combined impact of decabromodiphenyl ether and high fat exposure on non-alcoholic fatty liver disease in vivo and in vitro. | 2021 | Details |
| A01416 | 34755918 | Environ Toxicol | Polystyrene nanoplastics potentiate the development of hepatic fibrosis in high fat diet fed mice. | 2021 | Details |
| A01437 | 34746195 | Front Med (Lausanne) | Liver Fibrosis and MAFLD: From Molecular Aspects to Novel Pharmacological Strategies. | 2021 | Details |
| A01440 | 34745924 | Avicenna J Phytomed | Gallic acid protects the liver against NAFLD induced by dust exposure and high-fat diet through inhibiting oxidative stress and repressing the inflammatory signaling pathways NF-kβ/TNF-α/IL-6 in Wistar rats. | 2022 | Details |
| A01441 | 34745420 | Oxid Med Cell Longev | The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD. | 2021 | Details |
| A01443 | 34743980 | Eur J Pharmacol | Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. | 2021 | Details |
| A01465 | 34737604 | J Inflamm Res | Curcumae Ameliorates Diethylnitrosamine-Induced Hepatocellular Carcinoma via Alteration of Oxidative Stress, Inflammation and Gut Microbiota. | 2021 | Details |
| A01466 | 34737121 | J Mol Cell Cardiol | NAFLD as a continuous driver in the whole spectrum of vascular disease. | 2021 | Details |
| A01490 | 34726357 | J Pediatr Endocrinol Metab | Increased hepcidin levels and non-alcoholic fatty liver disease in obese prepubertal children: a further piece to the complex puzzle of metabolic derangements. | 2021 | Details |
| A01503 | 34719928 | J Agric Food Chem | Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity. | 2021 | Details |
| A01511 | 34715296 | Free Radic Biol Med | Role of vitamin E in the treatment of non-alcoholic steatohepatitis. | 2021 | Details |
| A01524 | 34708231 | Sheng Li Xue Bao | [The role of SIRT6 in nonalcoholic steatohepatitis]. | 2021 | Details |
| A01533 | 34707201 | Sci Rep | Characterization of a murine model of endothelial dysfunction induced by chronic intraperitoneal administration of angiotensin II. | 2021 | Details |
| A01537 | 34706542 | J Agric Food Chem | Sulforaphane Regulates Glucose and Lipid Metabolisms in Obese Mice by Restraining JNK and Activating Insulin and FGF21 Signal Pathways. | 2021 | Details |
| A01541 | 34704009 | Metabol Open | Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models. | 2021 | Details |
| A01552 | 34697380 | Sci Rep | Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS. | 2021 | Details |
| A01554 | 34695558 | J Nutr Biochem | Nobiletin mitigates hepatocytes death, liver inflammation, and fibrosis in a murine model of NASH through modulating hepatic oxidative stress and mitochondrial dysfunction. | 2021 | Details |
| A01556 | 34694070 | Mol Syst Biol | Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients. | 2021 | Details |
| A01577 | 34687092 | Biofactors | Perspectives in liver redox imbalance: Toxicological and pharmacological aspects underlying iron overloading, nonalcoholic fatty liver disease, and thyroid hormone action. | 2021 | Details |
| A01585 | 34684653 | Nutrients | Coffeeberry Activates the CaMKII/CREB/BDNF Pathway, Normalizes Autophagy and Apoptosis Signaling in Nonalcoholic Fatty Liver Rodent Model. | 2021 | Details |
| A01590 | 34684455 | Nutrients | Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model. | 2021 | Details |
| A01599 | 34681787 | Int J Mol Sci | The Interplay between Insulin Resistance, Inflammation, Oxidative Stress, Base Excision Repair and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01601 | 34681695 | Int J Mol Sci | Astaxanthin Prevents Diet-Induced NASH Progression by Shaping Intrahepatic Immunity. | 2021 | Details |
| A01602 | 34681600 | Int J Mol Sci | Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling. | 2021 | Details |
| A01603 | 34681291 | Foods | Tebuconazole Fungicide Induces Lipid Accumulation and Oxidative Stress in HepG2 Cells. | 2021 | Details |
| A01609 | 34680522 | Biomedicines | Lipid Disorders in NAFLD and Chronic Kidney Disease. | 2021 | Details |
| A01611 | 34680486 | Biomedicines | Nonalcoholic Fatty Liver Disease and the Kidney: A Review. | 2021 | Details |
| A01614 | 34679681 | Antioxidants (Basel) | Ameliorative Effect of Annona muricata (Graviola) Extract on Hyperglycemia Induced Hepatic Damage in Type 2 Diabetic Mice. | 2021 | Details |
| A01622 | 34678374 | Toxicol Appl Pharmacol | Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3. | 2021 | Details |
| A01623 | 34678296 | Clin Chim Acta | The potential pathophysiological role of altered lipid metabolism and electronegative low-density lipoprotein (LDL) in non-alcoholic fatty liver disease and cardiovascular diseases. | 2021 | Details |
| A01649 | 34668765 | J Med Food | Ameliorative Effect of Myricetin on Nonalcoholic Fatty Liver Disease in ob/ob Mice. | 2021 | Details |
| A01660 | 34664288 | J Food Biochem | Sesamol ameliorates hepatic lipid accumulation and oxidative stress in steatosis HepG2 cells via the PPAR signaling pathway. | 2021 | Details |
| A01673 | 34659439 | Evid Based Complement Alternat Med | Ginsenoside Re Improves Inflammation and Fibrosis in Hepatic Tissue by Upregulating PPARγ Expression and Inhibiting Oxidative Stress in db/db Mice. | 2021 | Details |
| A01689 | 34653601 | J Nutr Biochem | Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways. | 2021 | Details |
| A01694 | 34652089 | J Sports Med Phys Fitness | Changes in mitochondrial biogenesis and fatty liver indicators in rat following continuous and high intensity interval training. | 2021 | Details |
| A01716 | 34642957 | J Food Sci | Heukcha, naturally post-fermented green tea extract, ameliorates diet-induced hypercholesterolemia and NAFLD in hamster. | 2021 | Details |
| A01733 | 34633706 | Hepatology | Gut microbiome features associated with liver fibrosis in Hispanics, a population at high risk for fatty liver disease. | 2021 | Details |
| A01746 | 34630100 | Front Pharmacol | CBD Alleviates Liver Injuries in Alcoholics With High-Fat High-Cholesterol Diet Through Regulating NLRP3 Inflammasome-Pyroptosis Pathway. | 2021 | Details |
| A01750 | 34629256 | Nutr Metab Cardiovasc Dis | Extent and features of liver steatosis in vitro pave the way to endothelial dysfunction without physical cell-to-cell contact. | 2021 | Details |
| A01787 | 34618611 | Immunopharmacol Immunotoxicol | Capillin protects against non-alcoholic steatohepatitis through suppressing NLRP3 inflammasome activation and oxidative stress. | 2021 | Details |
| A01788 | 34617537 | Food Funct | Kombuchas from green and black teas reduce oxidative stress, liver steatosis and inflammation, and improve glucose metabolism in Wistar rats fed a high-fat high-fructose diet. | 2021 | Details |
| A01810 | 34607007 | Fish Shellfish Immunol | Polysaccharide extract from pomelo fruitlet ameliorates diet-induced nonalcoholic fatty liver disease in hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀). | 2021 | Details |
| A01847 | 34591699 | J Med Food | Artichoke Extract Directly Suppresses Inflammation and Apoptosis in Hepatocytes During the Development of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01861 | 34585409 | J Food Biochem | Crataegus aronia prevents high-fat diet-induced hepatic steatosis in rats by activating AMPK-induced suppression of SREBP1 and activation of PPARα. | 2021 | Details |
| A01882 | 34574082 | Foods | AGL9: A Novel Hepatoprotective Peptide from the Larvae of Edible Insects Alleviates Obesity-Induced Hepatic Inflammation by Regulating AMPK/Nrf2 Signaling. | 2021 | Details |
| A01884 | 34573421 | Genes (Basel) | The Mitochondrial Trigger in an Animal Model of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01902 | 34566663 | Front Pharmacol | Preclinical Evidence of Berberine on Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Animal Studies. | 2021 | Details |
| A01909 | 34565074 | Rev Cardiovasc Med | Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease. | 2021 | Details |
| A01918 | 34563519 | J Lipid Res | Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis. | 2021 | Details |
| A01925 | 34560554 | Biomed Pharmacother | Regulation of decorin by ursolic acid protects against non-alcoholic steatohepatitis. | 2021 | Details |
| A01941 | 34558644 | Mol Med Rep | PPARγ attenuates hepatic inflammation and oxidative stress of non‑alcoholic steatohepatitis via modulating the miR‑21‑5p/SFRP5 pathway. | 2021 | Details |
| A01947 | 34557397 | Pediatr Gastroenterol Hepatol Nutr | Investigation of Thiol/Disulfide Balance in Obese Rats with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01960 | 34552698 | World J Hepatol | Association of non-alcoholic fatty liver disease and COVID-19: A literature review of current evidence. | 2021 | Details |
| A01962 | 34551612 | Future Med Chem | Xanthohumol alleviates T2DM-induced liver steatosis and fibrosis by mediating the NRF2/RAGE/NF-κB signaling pathway. | 2021 | Details |
| A01964 | 34550043 | Adipocyte | Sodium glucose cotransporter 2 inhibitor dapagliflozin depressed adiposity and ameliorated hepatic steatosis in high-fat diet induced obese mice. | 2021 | Details |
| A01970 | 34547477 | Ann Hepatol | Alternative splicing and liver disease. | 2021 | Details |
| A01990 | 34537182 | Anal Biochem | Cerebrovascular alterations in NAFLD: Is it increasing our risk of Alzheimer's disease? | 2021 | Details |
| A01992 | 34536498 | Life Sci | Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway. | 2021 | Details |
| A01998 | 34534913 | Redox Biol | Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death. | 2021 | Details |
| A02005 | 34533252 | J Biochem Mol Toxicol | Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation. | 2021 | Details |
| A02010 | 34531465 | Sci Rep | Oxidative stress and cardiometabolic biomarkers in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A02031 | 34525916 | Curr Med Chem | Beneficial Effects of Dietary Polyphenols in the Prevention and Treatment of NAFLD: Cell-Signaling Pathways Underlying Health Effects. | 2022 | Details |
| A02042 | 34522493 | Cureus | The Role of Vitamins in Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2021 | Details |
| A02080 | 34511460 | Georgian Med News | [METABOLIC FEATURES OF ADIPOSE TISSUE AND CLINICAL SIGNIFICANCE OF ADIPOKINS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE (REVIEW)]. | 2021 | Details |
| A02118 | 34500407 | Curr Opin Pharmacol | A double-edged sword: The Kelch-like ECH-associated protein 1-nuclear factor erythroid-derived 2-related factor 2-antioxidant response element pathway targeted pharmacological modulation in nonalcoholic fatty liver disease. | 2021 | Details |
| A02148 | 34486133 | J Food Biochem | Regulatory mechanisms of energy metabolism and inflammation in oleic acid-treated HepG2 cells from Lactobacillus acidophilus NX2-6 extract. | 2021 | Details |
| A02153 | 34484560 | Oxid Med Cell Longev | Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens. | 2021 | Details |
| A02161 | 34479550 | BMC Complement Med Ther | Administration of hydro-alcoholic extract of spinach improves oxidative stress and inflammation in high-fat diet-induced NAFLD rats. | 2021 | Details |
| A02171 | 34475864 | Front Microbiol | Metabolomic Predictors of Non-alcoholic Steatohepatitis and Advanced Fibrosis in Children. | 2021 | Details |
| A02178 | 34473313 | Methods Mol Biol | Therapeutic Effects of Resveratrol on Nonalcoholic Fatty Liver Disease Through Inflammatory, Oxidative Stress, Metabolic, and Epigenetic Modifications. | 2022 | Details |
| A02220 | 34455040 | Free Radic Biol Med | Mitochondrial dysfunction in mouse livers depleted of iron chaperone PCBP1. | 2021 | Details |
| A02233 | 34450307 | Pharmacol Res | Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis. | 2021 | Details |
| A02240 | 34449316 | Biomed Pharmacother | Jiuzhuan Huangjing Pills relieve mitochondrial dysfunction and attenuate high-fat diet-induced metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
| A02250 | 34446275 | Maturitas | The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause. | 2021 | Details |
| A02256 | 34445549 | Int J Mol Sci | Kaempferol and Kaempferide Attenuate Oleic Acid-Induced Lipid Accumulation and Oxidative Stress in HepG2 Cells. | 2021 | Details |
| A02268 | 34441028 | Medicina (Kaunas) | Phytotherapy as Multi-Hit Therapy to Confront the Multiple Pathophysiology in Non-Alcoholic Fatty Liver Disease: A Systematic Review of Experimental Interventions. | 2021 | Details |
| A02278 | 34439562 | Antioxidants (Basel) | Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. | 2021 | Details |
| A02280 | 34439474 | Antioxidants (Basel) | Garcinia cambogia Ameliorates Non-Alcoholic Fatty Liver Disease by Inhibiting Oxidative Stress-Mediated Steatosis and Apoptosis through NRF2-ARE Activation. | 2021 | Details |
| A02281 | 34439470 | Antioxidants (Basel) | Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE-/- Mice. | 2021 | Details |
| A02285 | 34437407 | Toxins (Basel) | Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans. | 2021 | Details |
| A02290 | 34434943 | Front Med (Lausanne) | Role of Carnitine in Non-alcoholic Fatty Liver Disease and Other Related Diseases: An Update. | 2021 | Details |