Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09803 | 31604171 | Atherosclerosis | Visceral adipose tissue volume is associated with premature atherosclerosis in early type 2 diabetes mellitus independent of traditional risk factors. | 2019 | Details |
| A09804 | 31604107 | Life Sci | Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome. | 2019 | Details |
| A09805 | 31604029 | Am J Physiol Gastrointest Liver Physiol | Intermittent restraint-induced sympathetic activation attenuates hepatic steatosis and inflammation in a high-fat diet-fed mouse model. | 2019 | Details |
| A09814 | 31600750 | Digestion | Rodent Models of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09815 | 31599882 | Rev Invest Clin | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1, NON-ALCOHOLIC FATTY LIVER DISEASE, AND ITS RELATIONSHIP WITH FRUCTOSE CONSUMPTION IN CHILDREN WITH OBESITY. | 2019 | Details |
| A09822 | 31598135 | Therap Adv Gastroenterol | Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2019 | Details |
| A09839 | 31594102 | Zhonghua Gan Zang Bing Za Zhi | [Research advances in the relationship between nonalcoholic fatty fiver disease and sarcopenia]. | 2019 | Details |
| A09848 | 31592078 | Hepatol Commun | Development of a Plasma Screening Panel for Pediatric Nonalcoholic Fatty Liver Disease Using Metabolomics. | 2019 | Details |
| A09855 | 31590127 | Biomed Pharmacother | Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage. | 2019 | Details |
| A09857 | 31589891 | J Hepatol | Change in hepatic fat content measured by MRI does not predict treatment-induced histological improvement of steatohepatitis. | 2019 | Details |
| A09860 | 31588816 | Arch Physiol Biochem | The association between retinol-binding protein 4 and prediabetes in obese patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A09865 | 31584681 | JAMA Netw Open | Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09872 | 31581241 | PLoS Comput Biol | A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data. | 2019 | Details |
| A09873 | 31581129 | Endocr Connect | Hyperinsulinaemia: does it tip the balance toward intrahepatic fat accumulation? | 2019 | Details |
| A09876 | 31578240 | Sci Transl Med | Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates. | 2019 | Details |
| A09888 | 31574193 | Mol Nutr Food Res | Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation. | 2019 | Details |
| A09892 | 31572482 | Arch Med Sci | Effect of Lactobacillus paracasei N1115 and fructooligosaccharides in nonalcoholic fatty liver disease. | 2019 | Details |
| A09901 | 31568518 | PLoS One | Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. | 2019 | Details |
| A09907 | 31566148 | Public Health Nutr | Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and elderly adults. | 2019 | Details |
| A09908 | 31565874 | Endocrinol Metab (Seoul) | Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective. | 2019 | Details |
| A09923 | 31558861 | World J Gastroenterol | Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways. | 2019 | Details |
| A09933 | 31554932 | Nat Rev Endocrinol | The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state. | 2019 | Details |
| A09936 | 31554294 | Medicina (Kaunas) | Relationship between Muscle Mass/Strength and Hepatic Fat Content in Post-Menopausal Women. | 2019 | Details |
| A09944 | 31551213 | Pak J Pharm Sci | Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients. | 2019 | Details |
| A09952 | 31545283 | Biomed Pharmacother | Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression. | 2019 | Details |
| A09967 | 31541591 | J Pineal Res | Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner. | 2019 | Details |
| A09969 | 31540903 | Diabetes Care | Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial. | 2019 | Details |
| A09978 | 31538291 | Endocrine | Nonalcoholic fatty liver disease in women with polycystic ovary syndrome. | 2019 | Details |
| A09983 | 31536725 | Eur J Pharmacol | Farnesoid X nuclear receptor agonists for the treatment of nonalcoholic steatohepatitis. | 2019 | Details |
| A09984 | 31536600 | PLoS One | Asprosin response in hypoglycemia is not related to hypoglycemia unawareness but rather to insulin resistance in type 1 diabetes. | 2019 | Details |
| A09986 | 31535735 | Nutr Clin Pract | Nonalcoholic Fatty Pancreas Disease. | 2019 | Details |
| A09987 | 31535207 | J Gastroenterol | Association between body size-metabolic phenotype and nonalcoholic steatohepatitis and significant fibrosis. | 2019 | Details |
| A09990 | 31534089 | Intern Med | Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09999 | 31530849 | Sci Rep | Controlling Obesity and Metabolic Diseases by Hydrodynamic Delivery of a Fusion Gene of Exendin-4 and α1 Antitrypsin. | 2019 | Details |
| A10002 | 31529722 | Hepatology | Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice. | 2020 | Details |
| A10003 | 31529495 | Hepatology | Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3. | 2020 | Details |
| A10006 | 31528245 | World J Hepatol | Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. | 2019 | Details |
| A10007 | 31527322 | J Atheroscler Thromb | Association of Fetuin-B with Subclinical Atherosclerosis in Obese Chinese Adults. | 2019 | Details |
| A10009 | 31526528 | J Pediatr | The Contribution of the Adipose Tissue-Liver Axis in Pediatric Patients with Nonalcoholic Fatty Liver Disease after Laparoscopic Sleeve Gastrectomy. | 2019 | Details |
| A10014 | 31523999 | Expert Opin Investig Drugs | Elafibranor: a potential drug for the treatment of nonalcoholic steatohepatitis (NASH). | 2019 | Details |
| A10023 | 31521175 | Lipids Health Dis | Variations in hepatic lipid species of age-matched male mice fed a methionine-choline-deficient diet and housed in different animal facilities. | 2019 | Details |
| A10035 | 31518478 | Liver Transpl | Delayed Sleeve Gastrectomy Following Liver Transplantation: A 5-Year Experience. | 2019 | Details |
| A10039 | 31517324 | J Gastrointestin Liver Dis | Effects of Dietary Intervention on Gut Microbiota and Metabolic-Nutritional Profile of Outpatients with Non-Alcoholic Steatohepatitis: a Randomized Clinical Trial. | 2019 | Details |
| A10041 | 31516268 | J Clin Exp Hepatol | Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges. | 2019 | Details |
| A10042 | 31516267 | J Clin Exp Hepatol | Screening of Cardiovascular Disease in Nonalcoholic Fatty Liver Disease: Whom and How? | 2019 | Details |
| A10051 | 31512431 | Adv Gerontol | [The effect of high-dose metformin on the metabolic parameters and functional state of the liver of agouti-mice with the melanocortin obesity.] | 2019 | Details |
| A10054 | 31510077 | Nutrients | A Low Iron Diet Protects from Steatohepatitis in a Mouse Model. | 2019 | Details |
| A10056 | 31506976 | Hepatology | Vitamin D Receptor Activation in Liver Macrophages Ameliorates Hepatic Inflammation, Steatosis, and Insulin Resistance in Mice. | 2020 | Details |
| A10074 | 31500354 | Cells | Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. | 2019 | Details |
| A10076 | 31497874 | Br J Pharmacol | Delayed intervention with a novel SGLT2 inhibitor NGI001 suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice. | 2019 | Details |
| A10078 | 31497742 | Hepatol Commun | Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance. | 2019 | Details |
| A10082 | 31496048 | Physiol Rep | Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. | 2019 | Details |
| A10087 | 31493247 | Hormones (Athens) | Selenium and selenoprotein P in nonalcoholic fatty liver disease. | 2019 | Details |
| A10094 | 31488477 | BMJ Open | Association between nut intake and non-alcoholic fatty liver disease risk: a retrospective case-control study in a sample of Chinese Han adults. | 2019 | Details |
| A10098 | 31485221 | Int J Endocrinol | Compound C Protects Mice from HFD-Induced Obesity and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10099 | 31484323 | Nutrients | Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. | 2019 | Details |
| A10105 | 31482785 | Am J Trop Med Hyg | Opisthorchis viverrini Infection Augments the Severity of Nonalcoholic Fatty Liver Disease in High-Fat/High-Fructose Diet-Fed Hamsters. | 2019 | Details |
| A10106 | 31482741 | Arch Physiol Biochem | Low level of adiponectin predicts the development of Nonalcoholic fatty liver disease: is it irrespective to visceral adiposity index, visceral adipose tissue thickness and other obesity indices? | 2019 | Details |
| A10116 | 31477078 | BMC Endocr Disord | Cholecystectomy versus central obesity or insulin resistance in relation to the risk of nonalcoholic fatty liver disease: the third US National Health and Nutrition Examination Survey. | 2019 | Details |
| A10125 | 31474632 | Yakugaku Zasshi | [Role of Angiogenesis and Chronic Inflammation in Fat Hypertrophy in NASH Pathology]. | 2019 | Details |
| A10131 | 31473346 | Biochim Biophys Acta Mol Cell Biol Lipids | Exercise regulates lipid droplet dynamics in normal and fatty liver. | 2019 | Details |
| A10134 | 31472955 | Biochem Biophys Res Commun | Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice. | 2019 | Details |
| A10139 | 31470786 | Curr Pharm Des | A Mitochondrial Approach to Cardiovascular Risk and Disease. | 2019 | Details |
| A10143 | 31470414 | Endocr Connect | Insulin resistance associates with hepatic lobular inflammation in subjects with obesity. | 2019 | Details |
| A10149 | 31469122 | Pol Arch Intern Med | Serum pentraxin 3 concentration in patients with type 2 diabetes and nonalcoholic fatty liver disease. | 2019 | Details |
| A10150 | 31467918 | Biomed Res Int | Abdominal Obesity as a Predictive Factor of Nonalcoholic Fatty Liver Disease Assessed by Ultrasonography and Transient Elastography in Polycystic Ovary Syndrome and Healthy Women. | 2019 | Details |
| A10166 | 31462971 | Comput Struct Biotechnol J | Hallmarks of Aging in the Liver. | 2019 | Details |
| A10167 | 31460789 | Am J Physiol Gastrointest Liver Physiol | Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of nonalcoholic steatohepatitis. | 2019 | Details |
| A10168 | 31460584 | Arq Gastroenterol | N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL. | 2019 | Details |
| A10178 | 31449538 | PLoS One | Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight. | 2019 | Details |
| A10182 | 31446562 | Obes Surg | Intraoperative Liver Biopsy During Adolescent Bariatric Surgery: Is It Really Necessary? | 2020 | Details |
| A10201 | 31436362 | Liver Int | Plasma N-terminal propeptide of type III procollagen accurately predicts liver fibrosis severity in children with non-alcoholic fatty liver disease. | 2019 | Details |
| A10210 | 31430977 | Int J Mol Sci | Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. | 2019 | Details |
| A10217 | 31428049 | Front Endocrinol (Lausanne) | The Liver in Children With Metabolic Syndrome. | 2019 | Details |
| A10218 | 31426291 | Int J Mol Sci | Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease. | 2019 | Details |
| A10220 | 31425956 | Diabetes Metab Syndr | A review of synbiotic efficacy in non-alcoholic fatty liver disease as a therapeutic approach. | 2019 | Details |
| A10223 | 31422074 | Arch Biochem Biophys | CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation. | 2019 | Details |
| A10233 | 31419514 | J Hepatol | Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development. | 2019 | Details |
| A10234 | 31419466 | Mol Cell Endocrinol | Empaglifozin mitigates NAFLD in high-fat-fed mice by alleviating insulin resistance, lipogenesis and ER stress. | 2019 | Details |
| A10235 | 31419414 | Clin Chim Acta | Fibroblast growth factor 21 in lipid metabolism and non-alcoholic fatty liver disease. | 2019 | Details |
| A10239 | 31417486 | Front Neurol | Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration. | 2019 | Details |
| A10240 | 31415794 | Mol Cell Endocrinol | Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A10248 | 31412686 | Genes (Basel) | Transcriptomic Analysis of Porcine Granulosa Cells Overexpressing Retinol Binding Protein 4. | 2019 | Details |
| A10249 | 31412267 | Eur J Pharmacol | Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways. | 2019 | Details |
| A10258 | 31408586 | Mol Nutr Food Res | Lycopene Alleviates Obesity-Induced Inflammation and Insulin Resistance by Regulating M1/M2 Status of Macrophages. | 2019 | Details |
| A10259 | 31408567 | Hepatol Res | Identification of two microRNA nodes as potential cooperative modulators of liver metabolism. | 2019 | Details |
| A10260 | 31408437 | J Clin Invest | Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis. | 2019 | Details |
| A10264 | 31406506 | J Biol Eng | Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model. | 2019 | Details |
| A10279 | 31401392 | Biomed Pharmacother | Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. | 2019 | Details |
| A10281 | 31401193 | EBioMedicine | Simulation of gastric bypass effects on glucose metabolism and non-alcoholic fatty liver disease with the Sleeveballoon device. | 2019 | Details |
| A10283 | 31400075 | Kaohsiung J Med Sci | The relationship between nonalcoholic fatty liver disease and pediatric congenital hypothyroidism patients. | 2019 | Details |
| A10292 | 31397492 | Clin Exp Pharmacol Physiol | Insulin-like growth factor binding protein 7 accelerates hepatic steatosis and insulin resistance in non-alcoholic fatty liver disease. | 2019 | Details |
| A10293 | 31396538 | J Diabetes Res | Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes. | 2019 | Details |
| A10295 | 31394881 | Nutrients | Non-Alcoholic Fatty Liver Disease is Associated with Higher Metabolic Expenditure in Overweight and Obese Subjects: A Case-Control Study. | 2019 | Details |
| A10298 | 31393852 | JCI Insight | Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. | 2019 | Details |
| A10315 | 31389294 | Epigenetics | Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation. | 2019 | Details |
| A10316 | 31388695 | Diabetologia | Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis. | 2019 | Details |
| A10318 | 31388627 | Hepatol Commun | Associations Between Body Fat, Muscle Mass, and Nonalcoholic Fatty Liver Disease: A Population-Based Study. | 2019 | Details |
| A10322 | 31388398 | World J Hepatol | Rise of sodium-glucose cotransporter 2 inhibitors in the management of nonalcoholic fatty liver disease. | 2019 | Details |
| A10329 | 31387169 | Biomed Pharmacother | Mitochondrial dysfunction in high-fat diet-induced nonalcoholic fatty liver disease: The alleviating effect and its mechanism of Polygonatum kingianum. | 2019 | Details |