Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06973 | 32682050 | J Hepatol | Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view. | 2020 | Details |
| A06975 | 32680977 | Aging (Albany NY) | Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway. | 2020 | Details |
| A06979 | 32677717 | Diabetes Metab Res Rev | NAFLD in type 2 diabetes mellitus: Still many challenging questions. | 2020 | Details |
| A06981 | 32674529 | Clin Mol Hepatol | Evidence-based clinical advice for nutrition and dietary weight loss strategies for the management of NAFLD and NASH. | 2020 | Details |
| A06982 | 32674425 | Nutrients | Current Trends of Essential Trace Elements in Patients with Chronic Liver Diseases. | 2020 | Details |
| A06983 | 32674154 | J Appl Lab Med | Low-Density Lipoprotein (LDL)-Triglyceride and Its Ratio to LDL-Cholesterol as Diagnostic Biomarkers for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06984 | 32673798 | Mol Metab | Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis. | 2020 | Details |
| A06987 | 32671584 | Dig Dis Sci | Preferred Noninvasive Testing for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06988 | 32671116 | J Immunol Res | Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity. | 2020 | Details |
| A06992 | 32670278 | Front Immunol | Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07000 | 32665525 | Gastroenterol Nurs | Ulcerative Colitis as an Independent Risk Factor for Hepatic Steatosis. | 2021 | Details |
| A07002 | 32664153 | Medicine (Baltimore) | Correlation between the small dense LDL level and nonalcoholic fatty liver disease: Possibility of a new biomarker. | 2020 | Details |
| A07011 | 32660130 | Metabolites | Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07013 | 32657776 | J Clin Invest | AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes. | 2020 | Details |
| A07019 | 32655229 | J Clin Exp Hepatol | Vascular Endothelial Growth Factor Promotes Proliferation of Epithelial Cell Adhesion Molecule-Positive Cells in Nonalcoholic Steatohepatitis. | 2019 | Details |
| A07021 | 32654868 | J Formos Med Assoc | Non-alcoholic fatty liver disease: A review with clinical and pathological correlation. | 2020 | Details |
| A07029 | 32652744 | Liver Int | MR elastography-based liver fibrosis correlates with liver events in nonalcoholic fatty liver patients: A multicenter study. | 2020 | Details |
| A07030 | 32652145 | Gastroenterology | Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07031 | 32651233 | J Biol Chem | From overnutrition to liver injury: AMP-activated protein kinase in nonalcoholic fatty liver diseases. | 2020 | Details |
| A07033 | 32650421 | Cells | Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07040 | 32647367 | Eur J Clin Nutr | The efficacy of flaxseed and hesperidin on non-alcoholic fatty liver disease: an open-labeled randomized controlled trial. | 2020 | Details |
| A07055 | 32638913 | Rev Col Bras Cir | Comparison of the severity of non-alcoholic fatty liver disease in diabetic and non-diabetic obese patients. | 2020 | Details |
| A07057 | 32638541 | J Cachexia Sarcopenia Muscle | Association between muscle strength and advanced fibrosis in non-alcoholic fatty liver disease: a Korean nationwide survey. | 2020 | Details |
| A07058 | 32638496 | Liver Int | Non-invasive risk scores do not reliably identify future cirrhosis or hepatocellular carcinoma in Type 2 diabetes: The Edinburgh type 2 diabetes study. | 2020 | Details |
| A07059 | 32638492 | Aging Cell | Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. | 2020 | Details |
| A07061 | 32637906 | JHEP Rep | The liver matrisome - looking beyond collagens. | 2020 | Details |
| A07062 | 32636281 | BMJ Open | Protocol for a phase IV, open-label feasibility study investigating non-invasive markers of hepatic fibrosis in people living with HIV-1 and non-alcoholic fatty liver disease randomised to receiving optimised background therapy (OBT) plus maraviroc or OBT alone. | 2020 | Details |
| A07065 | 32634767 | J Trace Elem Med Biol | The sex-specific effects of blood lead, mercury, and cadmium levels on hepatic steatosis and fibrosis: Korean nationwide cross-sectional study. | 2020 | Details |
| A07066 | 32634622 | Clin Gastroenterol Hepatol | Real-World Burden of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07067 | 32634278 | J Intern Med | Liver mitochondrial DNA damage and genetic variability of Cytochrome b - a key component of the respirasome - drive the severity of fatty liver disease. | 2020 | Details |
| A07068 | 32633900 | Liver Int | Training of hepatology providers improves the screening and resultant interventions for alcohol use disorder. | 2020 | Details |
| A07074 | 32631250 | BMC Gastroenterol | Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A07076 | 32630732 | Antioxidants (Basel) | Serum Malondialdehyde is Associated with Non-Alcoholic Fatty Liver and Related Liver Damage Differentially in Men and Women. | 2020 | Details |
| A07082 | 32629394 | EBioMedicine | MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD. | 2020 | Details |
| A07083 | 32629127 | Clin Gastroenterol Hepatol | Enhanced Liver Fibrosis Score Can Be Used to Predict Liver-Related Events in Patients With Nonalcoholic Steatohepatitis and Compensated Cirrhosis. | 2020 | Details |
| A07084 | 32629123 | Clin Gastroenterol Hepatol | Lean Americans With Nonalcoholic Fatty Liver Disease Have Lower Rates of Cirrhosis and Comorbid Diseases. | 2020 | Details |
| A07087 | 32627871 | J Gastroenterol Hepatol | Patient-reported outcomes in patients with non-alcoholic fatty liver disease: A narrative review of Chronic Liver Disease Questionnaire-non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. | 2020 | Details |
| A07089 | 32626837 | Hepatol Commun | Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice. | 2020 | Details |
| A07090 | 32626832 | Hepatol Commun | Health Care Use and Costs Among Patients With Nonalcoholic Steatohepatitis With Advanced Fibrosis Using the Fibrosis-4 Score. | 2020 | Details |
| A07091 | 32626829 | Hepatol Commun | Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis. | 2020 | Details |
| A07092 | 32626782 | J Diabetes Res | Thrombospondin-1: A Key Protein That Induces Fibrosis in Diabetic Complications. | 2020 | Details |
| A07098 | 32623006 | Clin Gastroenterol Hepatol | Prevalence of Liver Steatosis and Fibrosis Detected by Transient Elastography in Adolescents in the 2017-2018 National Health and Nutrition Examination Survey. | 2020 | Details |
| A07102 | 32621970 | Clin Gastroenterol Hepatol | Monitoring Occurrence of Liver-Related Events and Survival by Transient Elastography in Patients With Nonalcoholic Fatty Liver Disease and Compensated Advanced Chronic Liver Disease. | 2020 | Details |
| A07103 | 32621944 | J Hepatol | Repeated FIB-4 measurements can help identify individuals at risk of severe liver disease. | 2020 | Details |
| A07104 | 32621584 | Endocr Connect | Fighting liver fat. | 2020 | Details |
| A07107 | 32621046 | Cardiovasc Drugs Ther | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model. | 2021 | Details |
| A07108 | 32620763 | Nat Commun | Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation. | 2020 | Details |
| A07110 | 32619269 | FEBS Lett | SHP-1 ameliorates nonalcoholic steatohepatitis by inhibiting proinflammatory cytokine production. | 2020 | Details |
| A07111 | 32619031 | Diabet Med | Mechanisms, screening modalities and treatment options for individuals with non-alcoholic fatty liver disease and type 2 diabetes. | 2020 | Details |
| A07117 | 32616276 | Can J Diabetes | Liver Stiffness Is Associated With Progression of Albuminuria in Adults With Type 2 Diabetes: Nonalcoholic Fatty Disease Cohort Study. | 2020 | Details |
| A07118 | 32615709 | Endocrinol Metab (Seoul) | Noninvasive Evaluation of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07124 | 32613718 | Diabetes Obes Metab | Vitamin D for treatment of non-alcoholic fatty liver disease detected by transient elastography: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
| A07125 | 32613381 | Cell Biol Toxicol | Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists. | 2020 | Details |
| A07126 | 32612827 | SAGE Open Med | Nonalcoholic fatty liver disease and cardiovascular disease phenotypes. | 2020 | Details |
| A07128 | 32610115 | J Hepatol | Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials. | 2020 | Details |
| A07129 | 32610095 | Cell Metab | A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. | 2020 | Details |
| A07132 | 32607889 | Methods Mol Biol | An Obesogenic Dietary Mouse Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07138 | 32606597 | Drug Des Devel Ther | Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent. | 2020 | Details |
| A07141 | 32605253 | Cancers (Basel) | Current and Future Treatments in the Fight Against Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07146 | 32603050 | Acta Gastroenterol Belg | Angiogenesis in the progression of non-alcoholic fatty liver disease. | 2020 | Details |
| A07148 | 32602214 | Hepatol Res | Clinical and anthropometric characteristics of non-obese non-alcoholic fatty liver disease subjects in Japan. | 2020 | Details |
| A07156 | 32598051 | Aliment Pharmacol Ther | Clinical assessment for high-risk patients with non-alcoholic fatty liver disease in primary care and diabetology practices. | 2020 | Details |
| A07157 | 32597705 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial oxidative injury: a key player in nonalcoholic fatty liver disease. | 2020 | Details |
| A07160 | 32595949 | F1000Res | Dyslipidemia as a risk factor for liver fibrosis progression in a multicentric population with non-alcoholic steatohepatitis. | 2020 | Details |
| A07167 | 32594797 | Hypertension | Nonalcoholic Fatty Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories. | 2020 | Details |
| A07174 | 32592770 | Eur J Pharmacol | Hepatoprotective effects of ZLY16, a dual peroxisome proliferator-activated receptor α/δ agonist, in rodent model of nonalcoholic steatohepatitis. | 2020 | Details |
| A07183 | 32591434 | Gut | Loss of hepatic Mboat7 leads to liver fibrosis. | 2020 | Details |
| A07187 | 32589269 | Eur J Clin Invest | Genetic predisposition in metabolic-dysfunction-associated fatty liver disease and cardiovascular outcomes-Systematic review. | 2020 | Details |
| A07188 | 32589264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | 2020 | Details |
| A07193 | 32587493 | Saudi J Med Med Sci | Prevalence and Clinical Characteristics of NAFLD in Chronic Liver Disease Patients from King Abdulaziz University Hospital, Jeddah. | 2020 | Details |
| A07196 | 32586422 | Reprod Fertil Dev | Ovulation mitigates fatty liver associated with reproductive suppression and oxidative stress in Damaraland mole-rats (Fukomys damarensis). | 2020 | Details |
| A07203 | 32583961 | Clin Transl Sci | Evolving Role for Pharmacotherapy in NAFLD/NASH. | 2020 | Details |
| A07205 | 32583813 | Am J Case Rep | Cirrhosis in a Young Child Due to Fatty Liver; Importance of Early Screening: A Case Report and Review of the Literature. | 2020 | Details |
| A07207 | 32583444 | J Gastroenterol Hepatol | Modest alcohol intake not associated with significant hepatic steatosis or more severe liver disease among patients with diabetes mellitus. | 2020 | Details |
| A07209 | 32581841 | Front Physiol | Dysregulated Neurovascular Control Underlies Declining Microvascular Functionality in People With Non-alcoholic Fatty Liver Disease (NAFLD) at Risk of Liver Fibrosis. | 2020 | Details |
| A07213 | 32579995 | Toxicol Lett | Long-term profile of serological biomarkers, hepatic inflammation, and fibrosis in a mouse model of non-alcoholic fatty liver disease. | 2020 | Details |
| A07223 | 32576050 | Gut Microbes | Sex-specific maternal calcium requirements for the prevention of nonalcoholic fatty liver disease by altering the intestinal microbiota and lipid metabolism in the high-fat-diet-fed offspring mice. | 2020 | Details |
| A07232 | 32573385 | Radiology | The Role of Multiparametric US of the Liver for the Evaluation of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07234 | 32572955 | J Cell Physiol | Expression of NF-κB, IL-6, and IL-10 genes, body composition, and hepatic fibrosis in obese patients with NAFLD-Combined effects of oleoylethanolamide supplementation and calorie restriction: A triple-blind randomized controlled clinical trial. | 2020 | Details |
| A07236 | 32572196 | Nat Biomed Eng | Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin. | 2020 | Details |
| A07243 | 32570776 | Int J Mol Sci | Epidemiology: Pathogenesis, and Diagnostic Strategy of Diabetic Liver Disease in Japan. | 2020 | Details |
| A07244 | 32569680 | Metabolism | Metabolic liver disease in diabetes - From mechanisms to clinical trials. | 2020 | Details |
| A07254 | 32566088 | Oxid Med Cell Longev | Cholesterol Induces Nrf-2- and HIF-1α-Dependent Hepatocyte Proliferation and Liver Regeneration to Ameliorate Bile Acid Toxicity in Mouse Models of NASH and Fibrosis. | 2020 | Details |
| A07260 | 32562818 | Pharmacol Res | ZLY032, the first-in-class dual FFA1/PPARδ agonist, improves glucolipid metabolism and alleviates hepatic fibrosis. | 2020 | Details |
| A07266 | 32561790 | Sci Rep | The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07273 | 32559006 | Liver Int | Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. | 2020 | Details |
| A07279 | 32557741 | J Gastroenterol Hepatol | Clinical profile of non-alcoholic fatty liver disease in nonobese patients. | 2020 | Details |
| A07280 | 32557192 | Hepatol Int | Portal inflammation predicts renal dysfunction in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A07281 | 32556752 | Surg Endosc | Long-term effects of one-anastomosis gastric bypass on liver histopathology in NAFLD cases: a prospective study. | 2020 | Details |
| A07283 | 32555989 | Arch Endocrinol Metab | Nonalcoholic fatty liver disease in women with polycystic ovary syndrome: associated factors and noninvasive fibrosis staging in a single Brazilian center. | 2020 | Details |
| A07284 | 32555268 | Sci Rep | Improved survival after treatments of patients with nonalcoholic fatty liver disease associated hepatocellular carcinoma. | 2020 | Details |
| A07292 | 32553765 | Gastroenterology | Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis. | 2020 | Details |
| A07297 | 32552182 | Expert Opin Investig Drugs | Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH). | 2020 | Details |
| A07304 | 32546802 | Sci Rep | Liver-specific knockout of B cell lymphoma 6 suppresses progression of non-alcoholic steatohepatitis in mice. | 2020 | Details |
| A07306 | 32546444 | Dig Liver Dis | Increased risk of acute liver failure by pain killer drugs in NAFLD: Focus on nuclear receptors and their coactivators. | 2020 | Details |
| A07307 | 32545650 | Nutrients | Serum Mac-2 Binding Protein Levels Associate with Metabolic Parameters and Predict Liver Fibrosis Progression in Subjects with Fatty Liver Disease: A 7-Year Longitudinal Study. | 2020 | Details |
| A07308 | 32545637 | Biology (Basel) | Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps. | 2020 | Details |
| A07313 | 32543284 | Expert Opin Pharmacother | Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis. | 2020 | Details |
| A07317 | 32541239 | Eur J Gastroenterol Hepatol | The impact of primary biliary cholangitis on non-alcoholic fatty liver disease. | 2021 | Details |
| A07319 | 32540736 | Diabetes Metab Syndr | Metabolic dysfunction associated fatty liver disease increases risk of severe Covid-19. | 2020 | Details |