Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15480 | 28883393 | Nat Commun | Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function. | 2017 | Details |
| A15490 | 28878132 | JCI Insight | Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis. | 2017 | Details |
| A15494 | 28877220 | PLoS One | Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways. | 2017 | Details |
| A15508 | 28869506 | Int J Mol Sci | Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases. | 2017 | Details |
| A15513 | 28867301 | Cell Metab | Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases. | 2017 | Details |
| A15514 | 28867186 | Biochem Biophys Res Commun | Dietary β-conglycinin prevents acute ethanol-induced fatty liver in mice. | 2017 | Details |
| A15524 | 28862329 | J Sci Food Agric | Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. | 2017 | Details |
| A15545 | 28849786 | Nat Rev Endocrinol | SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology. | 2017 | Details |
| A15550 | 28847729 | Biochem Biophys Res Commun | Hepatic GDF15 is regulated by CHOP of the unfolded protein response and alleviates NAFLD progression in obese mice. | 2017 | Details |
| A15558 | 28844958 | Biochim Biophys Acta Mol Basis Dis | Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet. | 2017 | Details |
| A15560 | 28843826 | Eur J Pharmacol | Zoledronic acid, an FPPS inhibitor, ameliorates liver steatosis through inhibiting hepatic de novo lipogenesis. | 2017 | Details |
| A15567 | 28840697 | Zhongguo Zhong Yao Za Zhi | [Effect of Psoralea corylifolia in treating fatty liver disease in juvenal mouse by inhibiting hepatic NF-κB activation]. | 2017 | Details |
| A15588 | 28825992 | J Nutr Biochem | Effects of delta-tocotrienol on obesity-related adipocyte hypertrophy, inflammation and hepatic steatosis in high-fat-fed mice. | 2017 | Details |
| A15600 | 28820447 | Int J Mol Sci | Comprehensive Study of Multiple Stages Progressing to Nonalcoholic Steatohepatitis with Subsequent Fibrosis in SD Rats. | 2017 | Details |
| A15602 | 28817690 | PLoS One | Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats. | 2017 | Details |
| A15612 | 28811572 | Sci Rep | Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice. | 2017 | Details |
| A15615 | 28809727 | Ann Hepatol | Models of non-Alcoholic Fatty Liver Disease and Potential Translational Value: the Effects of 3,5-L-diiodothyronine. | 2018 | Details |
| A15627 | 28802563 | Gastroenterology | Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues. | 2017 | Details |
| A15632 | 28799714 | Mol Nutr Food Res | Potential Biological Effects of (-)-Epigallocatechin-3-gallate on the Treatment of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15637 | 28796629 | Environ Health Perspect | Hepatic Lipid Accumulation and Nrf2 Expression following Perinatal and Peripubertal Exposure to Bisphenol A in a Mouse Model of Nonalcoholic Liver Disease. | 2017 | Details |
| A15648 | 28789977 | Biochim Biophys Acta Mol Basis Dis | Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization. | 2017 | Details |
| A15673 | 28774777 | Mol Cell Endocrinol | Insights into the role of hepatocyte PPARα activity in response to fasting. | 2017 | Details |
| A15677 | 28770225 | Biomed Res Int | PEGylated Curcumin Derivative Attenuates Hepatic Steatosis via CREB/PPAR-γ/CD36 Pathway. | 2017 | Details |
| A15688 | 28759727 | Can J Physiol Pharmacol | The beneficial effects of resveratrol on steatosis and mitochondrial oxidative stress in HepG2 cells. | 2017 | Details |
| A15696 | 28754826 | J Lipid Res | Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver. | 2017 | Details |
| A15698 | 28753963 | Nutrients | The Combined Intervention with Germinated Vigna radiata and Aerobic Interval Training Protocol Is an Effective Strategy for the Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD) and Other Alterations Related to the Metabolic Syndrome in Zucker Rats. | 2017 | Details |
| A15701 | 28752050 | Mol Metab | Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders. | 2017 | Details |
| A15717 | 28745372 | Mol Biosyst | Systems-level organization of non-alcoholic fatty liver disease progression network. | 2017 | Details |
| A15723 | 30603331 | Diabetol Int | Immune regulation of glucose and lipid metabolism. | 2017 | Details |
| A15724 | 28741793 | Liver Int | Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress. | 2017 | Details |
| A15734 | 28737815 | Food Funct | Isofraxidin, a coumarin component improves high-fat diet induced hepatic lipid homeostasis disorder and macrophage inflammation in mice. | 2017 | Details |
| A15741 | 28734036 | Mol Nutr Food Res | (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. | 2017 | Details |
| A15742 | 28733574 | Sci Rep | Metabolomic characteristics of cholesterol-induced non-obese nonalcoholic fatty liver disease in mice. | 2017 | Details |
| A15768 | 28719078 | Diabetes Obes Metab | Luseogliflozin improves liver fat deposition compared to metformin in type 2 diabetes patients with non-alcoholic fatty liver disease: A prospective randomized controlled pilot study. | 2017 | Details |
| A15772 | 28718215 | Hepatology | USP18 protects against hepatic steatosis and insulin resistance through its deubiquitinating activity. | 2017 | Details |
| A15795 | 28706189 | Sci Rep | Vertical sleeve gastrectomy reverses diet-induced gene-regulatory changes impacting lipid metabolism. | 2017 | Details |
| A15807 | 28699612 | Indian Pediatr | Relationship Between Immune Parameters and Non-alcoholic Fatty Liver Disease in Obese Children. | 2017 | Details |
| A15816 | 28695481 | Mol Biotechnol | A Novel Rat Model of Nonalcoholic Fatty Liver Disease Constructed Through CRISPR/Cas-Based Hydrodynamic Injection. | 2017 | Details |
| A15831 | 28691019 | Biomed Res Int | Fish Oil Feeding Modulates the Expression of Hepatic MicroRNAs in a Western-Style Diet-Induced Nonalcoholic Fatty Liver Disease Rat Model. | 2017 | Details |
| A15851 | 28680813 | FEBS Open Bio | Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease. | 2017 | Details |
| A15870 | 28676332 | Respir Physiol Neurobiol | Circulating exosomes in obstructive sleep apnea as phenotypic biomarkers and mechanistic messengers of end-organ morbidity. | 2017 | Details |
| A15888 | 28670394 | Am J Transl Res | PFP alleviates nonalcoholic steatohepatitis fatty liver in both Apo E-/- mice and Changliver cell[S]. | 2017 | Details |
| A15892 | 28667519 | Sci China Life Sci | Retinoic acid ameliorates high-fat diet-induced liver steatosis through sirt1. | 2017 | Details |
| A15893 | 28667176 | J Mol Endocrinol | miR-212-5p suppresses lipid accumulation by targeting FAS and SCD1. | 2017 | Details |
| A15927 | 28647361 | Biochem Biophys Res Commun | Apolipoprotein O expression in mouse liver enhances hepatic lipid accumulation by impairing mitochondrial function. | 2017 | Details |
| A15929 | 28647324 | Trends Endocrinol Metab | AMPK as a Therapeutic Target for Treating Metabolic Diseases. | 2017 | Details |
| A15937 | 28643888 | Mol Nutr Food Res | Combination of citrus polymethoxyflavones, green tea polyphenols, and Lychee extracts suppresses obesity and hepatic steatosis in high-fat diet induced obese mice. | 2017 | Details |
| A15938 | 28643267 | Protein Cell | New insight into inter-organ crosstalk contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). | 2017 | Details |
| A15949 | 28640216 | Nutrients | A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A15954 | 28638220 | World J Gastroenterol | Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats. | 2017 | Details |
| A15965 | 28635586 | Gene Expr | GC-1: A Thyromimetic With Multiple Therapeutic Applications in Liver Disease. | 2017 | Details |
| A15977 | 28629152 | Children (Basel) | The Association between Pediatric NAFLD and Common Genetic Variants. | 2017 | Details |
| A15978 | 28628909 | J Nutr Biochem | Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E). | 2017 | Details |
| A15985 | 28626963 | Exp Physiol | Exercise training modulates the hepatic renin-angiotensin system in fructose-fed rats. | 2017 | Details |
| A15996 | 28621339 | Nat Rev Endocrinol | Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance. | 2017 | Details |
| A15999 | 28620012 | Clin Sci (Lond) | Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes. | 2017 | Details |
| A16005 | 28615690 | Sci Rep | Cathepsin D regulates lipid metabolism in murine steatohepatitis. | 2017 | Details |
| A16023 | 28605664 | J Nutr Biochem | Soy compared with milk protein in a Western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats. | 2017 | Details |
| A16027 | 28602867 | J Ethnopharmacol | Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice. | 2017 | Details |
| A16049 | 28594915 | PLoS One | Conophylline inhibits non-alcoholic steatohepatitis in mice. | 2017 | Details |
| A16061 | 28587303 | Children (Basel) | The Role of Lipid and Lipoprotein Metabolism in Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16062 | 28587208 | Mar Drugs | Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models. | 2017 | Details |
| A16064 | 28587063 | Int J Mol Sci | A Relative Deficiency of Lysosomal Acid Lypase Activity Characterizes Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16073 | 28585211 | Adv Exp Med Biol | Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16074 | 28585204 | Adv Exp Med Biol | Insulin Resistance, Obesity and Lipotoxicity. | 2017 | Details |
| A16075 | 28584294 | Sci Rep | Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver. | 2017 | Details |
| A16080 | 28580278 | Mol Metab | FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis. | 2017 | Details |
| A16083 | 28578672 | Lipids Health Dis | Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice. | 2017 | Details |
| A16086 | 28577569 | Lipids Health Dis | Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes. | 2017 | Details |
| A16087 | 28577437 | Int Immunopharmacol | Rutin exhibits hepatoprotective effects in a mouse model of non-alcoholic fatty liver disease by reducing hepatic lipid levels and mitigating lipid-induced oxidative injuries. | 2017 | Details |
| A16094 | 28573213 | ACS Cent Sci | Chemoproteomic Profiling of Bile Acid Interacting Proteins. | 2017 | Details |
| A16100 | 28571771 | Food Chem Toxicol | The lemon balm extract ALS-L1023 inhibits obesity and nonalcoholic fatty liver disease in female ovariectomized mice. | 2017 | Details |
| A16104 | 28570612 | PLoS One | Caveolin1 protects against diet induced hepatic lipid accumulation in mice. | 2017 | Details |
| A16107 | 28566439 | Eur J Endocrinol | MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease. | 2017 | Details |
| A16114 | 28559541 | Int J Obes (Lond) | Adiponectin deficiency rescues high-fat diet-induced hepatic injury, apoptosis and autophagy loss despite persistent steatosis. | 2017 | Details |
| A16116 | 28558676 | BMC Endocr Disord | Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study. | 2017 | Details |
| A16129 | 28549240 | J Nutr Biochem | Dietary salecan reverts partially the metabolic gene expressions and NMR-based metabolomic profiles from high-fat-diet-induced obese rats. | 2017 | Details |
| A16130 | 28547778 | FEBS Lett | Deletion of HNF1α in hepatocytes results in fatty liver-related hepatocellular carcinoma in mice. | 2017 | Details |
| A16147 | 28539530 | Endocr J | Active form of vitamin D ameliorates non-alcoholic fatty liver disease by alleviating oxidative stress in a high-fat diet rat model. | 2017 | Details |
| A16152 | 28536120 | FASEB J | Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor. | 2017 | Details |
| A16155 | 28534819 | Int J Mol Sci | Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK. | 2017 | Details |
| A16169 | 28526925 | Eur J Nutr | Polyphenolic extract attenuates fatty acid-induced steatosis and oxidative stress in hepatic and endothelial cells. | 2017 | Details |
| A16177 | 28521680 | Curr Med Chem | Fatty Acids and Effects on In Vitro and In Vivo Models of Liver Steatosis. | 2019 | Details |
| A16180 | 28515456 | Sci Rep | Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet. | 2017 | Details |
| A16182 | 28514835 | Biomed Pharmacother | Genistein has beneficial effects on hepatic steatosis in high fat-high sucrose diet-treated rats. | 2017 | Details |
| A16192 | 28511152 | Wiad Lek | [Pathogenetic substantiation of complex treatment of nonalcoholic steatohepatitis and steatosis in patients with pre-diabetes and type 2 diabetes]. | 2017 | Details |
| A16194 | 28511018 | Appl Physiol Nutr Metab | Daytime increase in caloric intake without change in total 24-h caloric intake can increase adiposity but not total bodyweight in rats with inverted feeding pattern. | 2016 | Details |
| A16197 | 28508477 | Hepatology | The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance. | 2017 | Details |
| A16204 | 28507343 | Sci Rep | Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. | 2017 | Details |
| A16212 | 28505074 | Nutrients | NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet. | 2017 | Details |
| A16213 | 28504910 | J Med Food | Fermented Moringa oleifera Decreases Hepatic Adiposity and Ameliorates Glucose Intolerance in High-Fat Diet-Induced Obese Mice. | 2017 | Details |
| A16215 | 28504310 | J Physiol | Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis. | 2017 | Details |
| A16216 | 28503750 | Diabetes Obes Metab | Comparative effects of liraglutide 3 mg vs structured lifestyle modification on body weight, liver fat and liver function in obese patients with non-alcoholic fatty liver disease: A pilot randomized trial. | 2017 | Details |
| A16226 | 28500084 | J Endocrinol | Bisphenol A promotes hepatic lipid deposition involving Kupffer cells M1 polarization in male mice. | 2017 | Details |
| A16228 | 28498022 | Curr Med Res Opin | Thyroid hormone analogs for the treatment of dyslipidemia: past, present, and future. | 2017 | Details |
| A16233 | 28494548 | Zhonghua Gan Zang Bing Za Zhi | [The role of cytochrome P450 in nonalcoholic fatty liver induced by high-fat diet: a gene expression profile analysis]. | 2017 | Details |
| A16253 | 28483554 | Biochim Biophys Acta Mol Cell Biol Lipids | Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. | 2017 | Details |
| A16262 | 28480888 | Nat Commun | Hepatic p63 regulates steatosis via IKKβ/ER stress. | 2017 | Details |
| A16267 | 28478385 | J Biol Chem | Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism. | 2017 | Details |
| A16305 | 28468010 | Dig Dis | Nutrition and Liver Health. | 2017 | Details |