Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07497 | 32472598 | FASEB J | Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr-/- .Leiden mice. | 2020 | Details |
| A07500 | 32472367 | Curr Nutr Rep | Kefir in the Prevention and Treatment of Obesity and Metabolic Disorders. | 2020 | Details |
| A07504 | 32469428 | Diabetes Metab Res Rev | Adipose tissue remodelling in obese subjects is a determinant of presence and severity of fatty liver disease. | 2020 | Details |
| A07515 | 32461046 | Clin Chim Acta | Emerging role of Insig-1 in lipid metabolism and lipid disorders. | 2020 | Details |
| A07517 | 32460629 | Metab Syndr Relat Disord | The Morbidity and Comorbidity of Nonalcoholic Fatty Liver Disease and Different Glucose Intolerance Strata in a Community-Based Chinese Population. | 2020 | Details |
| A07527 | 32454814 | Gastroenterol Res Pract | A Low Creatinine to Body Weight Ratio Predicts the Incident Nonalcoholic Fatty Liver Disease in Nonelderly Chinese without Obesity and Dyslipidemia: A Retrospective Study. | 2020 | Details |
| A07531 | 32454173 | J Ethnopharmacol | An unbiased lipidomics approach identifies key lipid molecules as potential therapeutic targets of Dohongsamul-tang against non-alcoholic fatty liver diseases in a mouse model of obesity. | 2020 | Details |
| A07535 | 32451920 | Obes Surg | Elastic Fibers Density: a New Parameter of Improvement of NAFLD in Bariatric Surgery Patients. | 2020 | Details |
| A07537 | 32451205 | Ann Hepatol | Is there an association between commonly employed biomarkers of liver fibrosis and liver stiffness in the general population? | 2020 | Details |
| A07542 | 32450149 | Gastroenterology | Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122. | 2020 | Details |
| A07552 | 32445754 | Toxicol Appl Pharmacol | Adipose tissue-liver crosstalk during pathologic changes caused by vinyl chloride metabolites in mice. | 2020 | Details |
| A07555 | 32444690 | Sci Rep | Histological grading evaluation of non-alcoholic fatty liver disease after bariatric surgery: a retrospective and longitudinal observational cohort study. | 2020 | Details |
| A07556 | 32444289 | Semin Cell Dev Biol | Hepatic lipid droplet homeostasis and fatty liver disease. | 2020 | Details |
| A07557 | 32444241 | Clin Nutr | Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery. | 2020 | Details |
| A07564 | 32442908 | Cytokine | Gastric banding-associated weight loss diminishes hepatic Tsukushi expression. | 2020 | Details |
| A07569 | 32440680 | Inflamm Bowel Dis | Multidimensional Impact of Mediterranean Diet on IBD Patients. | 2021 | Details |
| A07570 | 32440483 | Adv Sci (Weinh) | Hepatocyte TMEM16A Deletion Retards NAFLD Progression by Ameliorating Hepatic Glucose Metabolic Disorder. | 2020 | Details |
| A07574 | 32439267 | Clin Nutr | Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet. | 2020 | Details |
| A07581 | 32436410 | Nutr Cancer | Combined Amelioration of Prebiotic Resveratrol and Probiotic Bifidobacteria on Obesity and Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07586 | 32434740 | Transplant Proc | The Utility of Assessing Liver Allograft Fibrosis and Steatosis Post-Liver Transplantation Using Transient Elastography With Controlled Attenuation Parameter. | 2020 | Details |
| A07593 | 32431528 | Diabetes Metab Syndr Obes | Association Between Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome with Gallstone Disease, South Iran: A Population-Based Study. | 2020 | Details |
| A07594 | 32431136 | J Clin Res Pediatr Endocrinol | Different Potent Glucocorticoids, Different Routes of Exposure but the Same Result: Iatrogenic Cushing’s Syndrome and Adrenal Insufficiency | 2020 | Details |
| A07598 | 32429653 | Pol J Pathol | Role of mast cells in the pathogenesis of liver fibrosis in nonalcoholic fatty liver disease. | 2020 | Details |
| A07602 | 32428560 | Biochim Biophys Acta Mol Basis Dis | Mitochondrial dysfunction in metabolic syndrome. | 2020 | Details |
| A07614 | 32420347 | Biomed Res Int | The Prevalence of NAFLD and Fibrosis in Bariatric Surgery Patients and the Reliability of Noninvasive Diagnostic Methods. | 2020 | Details |
| A07615 | 32420328 | Biomed Res Int | Prevalence of Metabolic Syndrome and Nonalcoholic Fatty Liver Disease among Premenopausal and Postmenopausal Women in Ho Municipality: A Cross-Sectional Study. | 2020 | Details |
| A07616 | 32420071 | Transl Lung Cancer Res | Non-alcoholic fatty liver disease is associated with immune checkpoint inhibitor-based treatment response in patients with non-small cell lung cancer with liver metastases. | 2020 | Details |
| A07618 | 32418749 | Ann Hepatol | A Latin American survey on demographic aspects of hospitalized, decompensated cirrhotic patients and the resources for their management. | 2020 | Details |
| A07627 | 32414883 | CMAJ Open | Risk stratification of patients with nonalcoholic fatty liver disease using a case identification pathway in primary care: a cross-sectional study. | 2020 | Details |
| A07636 | 32413340 | Lancet Gastroenterol Hepatol | Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis. | 2020 | Details |
| A07642 | 32411096 | Front Endocrinol (Lausanne) | Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue. | 2020 | Details |
| A07643 | 32410680 | Lipids Health Dis | Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio. | 2020 | Details |
| A07644 | 32410559 | Curr Drug Metab | Evaluating Lean Liver Volume as a Potential Scaler for In Vitro-In Vivo Extrapolation of Drug Clearance in Obesity Using the Model Drug Antipyrine. | 2020 | Details |
| A07650 | 32409495 | Arch Dis Child | Non-alcoholic fatty liver disease and childhood obesity. | 2020 | Details |
| A07651 | 32408667 | Int J Environ Res Public Health | The Bisphenol A Induced Oxidative Stress in Non-Alcoholic Fatty Liver Disease Male Patients: A Clinical Strategy to Antagonize the Progression of the Disease. | 2020 | Details |
| A07661 | 32405181 | J Clin Exp Hepatol | Natural History of Non-Alcoholic Fatty Liver Disease: A Study With Paired Liver Biopsies. | 2019 | Details |
| A07664 | 32404278 | Biochim Biophys Acta Mol Cell Biol Lipids | Niacin increases diet-induced hepatic steatosis in B6129 mice. | 2020 | Details |
| A07676 | 32396530 | J Clin Invest | Nonalcoholic fatty liver disease in CLOCK mutant mice. | 2020 | Details |
| A07678 | 32396388 | Am J Physiol Endocrinol Metab | β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro. | 2020 | Details |
| A07679 | 32394476 | Hepatology | Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH). | 2020 | Details |
| A07680 | 32392802 | Int J Mol Sci | Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats. | 2020 | Details |
| A07689 | 32390455 | Antioxid Redox Signal | Intestinal Dysbiosis and Development of Cardiometabolic Disorders in Childhood Cancer Survivors: A Critical Review. | 2020 | Details |
| A07696 | 32388251 | J Nutr Biochem | Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane. | 2020 | Details |
| A07697 | 32388250 | J Nutr Biochem | Targeting the gut microbiota with resveratrol: a demonstration of novel evidence for the management of hepatic steatosis. | 2020 | Details |
| A07699 | 32387461 | J Ethnopharmacol | Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress. | 2020 | Details |
| A07707 | 32383295 | Aliment Pharmacol Ther | Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis. | 2020 | Details |
| A07713 | 32381466 | J Pediatr | Glomerular Hyperfiltration Is Associated with Liver Disease Severity in Children with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07717 | 32377814 | Eur Radiol | Liver extracellular volume fraction values obtained with magnetic resonance imaging can quantitatively stage liver fibrosis: a validation study in monkeys with nonalcoholic steatohepatitis. | 2020 | Details |
| A07723 | 32376236 | Ann Hepatol | Blood lead level is associated with advanced liver fibrosis in patients with non-alcoholic fatty liver disease: A nationwide survey (NHANES 2011-2016). | 2020 | Details |
| A07730 | 32373514 | Front Oncol | Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer. | 2020 | Details |
| A07734 | 32372191 | Dig Dis Sci | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. | 2020 | Details |
| A07736 | 32370702 | Protein Pept Lett | Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions. | 2020 | Details |
| A07740 | 32369237 | J Dig Dis | Epidemiology of nonalcoholic fatty liver disease in non-obese populations: Meta-analytic assessment of its prevalence, genetic, metabolic, and histological profiles. | 2020 | Details |
| A07747 | 32365683 | Nutrients | Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07751 | 32365055 | J Clin Invest | Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes. | 2020 | Details |
| A07752 | 32364539 | J Clin Invest | Insulin-stimulated lipogenesis gets an epigenetic makeover. | 2020 | Details |
| A07755 | 32363679 | Diabetes Obes Metab | Intrahepatic fat, irrespective of ethnicity, is associated with reduced endogenous insulin clearance and hepatic insulin resistance in obese youths: A cross-sectional and longitudinal study from the Yale Pediatric NAFLD cohort. | 2020 | Details |
| A07756 | 32363320 | Hepatol Commun | Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07764 | 32360826 | Clin Gastroenterol Hepatol | Decreased Quality of Life Is Significantly Associated With Body Composition in Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07767 | 32360804 | Clin Gastroenterol Hepatol | Intragastric Balloon Placement Induces Significant Metabolic and Histologic Improvement in Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07772 | 32359748 | Clin Nutr ESPEN | Diagnostic of hepatic fibrosis with the XL probe of the Fibroscan versus biopsies in patients candidates to bariatric surgery. | 2020 | Details |
| A07775 | 32359355 | Cardiovasc Diabetol | Fatty liver index and development of cardiovascular disease in Koreans without pre-existing myocardial infarction and ischemic stroke: a large population-based study. | 2020 | Details |
| A07786 | 32354883 | In Vivo | Oral Recombinant Methioninase Prevents Nonalcoholic Fatty Liver Disease in Mice on a High Fat Diet. | 2021 | Details |
| A07788 | 32354858 | Diabetes | The Effects of B1344, a Novel Fibroblast Growth Factor 21 Analog, on Nonalcoholic Steatohepatitis in Nonhuman Primates. | 2020 | Details |
| A07790 | 32354071 | Pharmaceutics | NAFLD Aggravates Septic Shock Due to Inadequate Adrenal Response and 11β-HSDs Dysregulation in Rats. | 2020 | Details |
| A07793 | 32353385 | Toxicol Appl Pharmacol | Metabolomic-based assessment reveals dysregulation of lipid profiles in human liver cells exposed to environmental obesogens. | 2020 | Details |
| A07796 | 32353039 | PLoS Med | Metabolic risk factors and incident advanced liver disease in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of population-based observational studies. | 2020 | Details |
| A07799 | 32352682 | Clin Transl Gastroenterol | The Association Between Cholecystectomy, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease: A Population-Based Study. | 2020 | Details |
| A07801 | 32351917 | Front Pediatr | Nonalcoholic Fatty Liver Disease Is Associated With Low Skeletal Muscle Mass in Overweight/Obese Youths. | 2020 | Details |
| A07804 | 32351187 | Curr Diabetes Rev | Inter-Tissue and Intra-Tissue Co-Expression Networks in Human Metabolism: Morphological Evaluation of the Link Between Transcription Factors ERβ and NFAT in Morbid Obesity. | 2021 | Details |
| A07805 | 32351030 | Pediatr Obes | The relationship between pancreas steatosis and the risk of metabolic syndrome and insulin resistance in Chinese adolescents with concurrent obesity and non-alcoholic fatty liver disease. | 2020 | Details |
| A07807 | 32350271 | Nat Commun | Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease. | 2020 | Details |
| A07808 | 32350181 | J Nutr Sci Vitaminol (Tokyo) | Coleus forskohlii Extract Attenuated the Beneficial Effect of Diet-Treatment on NASH in Mouse Model. | 2020 | Details |
| A07809 | 32349939 | Ann Hepatol | Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity. | 2020 | Details |
| A07816 | 32347583 | FASEB J | Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. | 2020 | Details |
| A07818 | 32346285 | Drug Des Devel Ther | Radix Polygoni Multiflori and Its Main Component Emodin Attenuate Non-Alcoholic Fatty Liver Disease in Zebrafish by Regulation of AMPK Signaling Pathway. | 2020 | Details |
| A07832 | 32341017 | J Pharmacol Exp Ther | 7α,25-Dihydroxycholesterol Suppresses Hepatocellular Steatosis through GPR183/EBI2 in Mouse and Human Hepatocytes. | 2020 | Details |
| A07833 | 32340286 | Int J Mol Sci | Nutrition and Genetics in NAFLD: The Perfect Binomium. | 2020 | Details |
| A07834 | 32340264 | Int J Mol Sci | Integrative Strategy of Testing Systems for Identification of Endocrine Disruptors Inducing Metabolic Disorders-An Introduction to the OBERON Project. | 2020 | Details |
| A07843 | 32337295 | J Diabetes Res | Elevated Serum Level of Cytokeratin 18 M65ED Is an Independent Indicator of Cardiometabolic Disorders. | 2020 | Details |
| A07844 | 32337059 | BMJ Open Gastroenterol | Effectiveness of phosphatidylcholine as adjunctive therapy in improving liver function tests in patients with non-alcoholic fatty liver disease and metabolic comorbidities: real-life observational study from Russia. | 2020 | Details |
| A07847 | 32336033 | J Dig Dis | Non-obese patients with nonalcoholic fatty liver disease may use a lower liver stiffness cut-off to assess fibrosis stages. | 2020 | Details |
| A07853 | 32333910 | Gastroenterology | Role of Cannabis and Its Derivatives in Gastrointestinal and Hepatic Disease. | 2020 | Details |
| A07857 | 32333362 | Indian J Gastroenterol | The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease. | 2020 | Details |
| A07859 | 32331389 | Cells | The P2X7 Receptor and NLRP3 Axis in Non-Alcoholic Fatty Liver Disease: A Brief Review. | 2020 | Details |
| A07861 | 32331258 | Nutrients | Lemon Balm and Its Constituent, Rosmarinic Acid, Alleviate Liver Damage in an Animal Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07868 | 32329579 | Liver Int | Occult hepatitis B virus infection predicts non-alcoholic steatohepatitis in severely obese individuals from Italy. | 2020 | Details |
| A07870 | 32329085 | Hepatology | The L-α-Lysophosphatidylinositol/G Protein-Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis. | 2020 | Details |
| A07877 | 32325919 | Nutrients | Decreased Consumption of Added Fructose Reduces Waist Circumference and Blood Glucose Concentration in Patients with Overweight and Obesity. The DISFRUTE Study: A Randomised Trial in Primary Care. | 2020 | Details |
| A07882 | 32324317 | J Cell Mol Med | GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non-alcoholic fatty liver disease via microRNA-200 and the MAPK pathway. | 2020 | Details |
| A07884 | 32323349 | Aliment Pharmacol Ther | The PNPLA3 rs738409 GG genotype is associated with poorer prognosis in 239 patients with autoimmune hepatitis. | 2020 | Details |
| A07887 | 32322309 | Diabetol Metab Syndr | Effect of circulating exosomes derived from normal-weight and obese women on gluconeogenesis, glycogenesis, lipogenesis and secretion of FGF21 and fetuin A in HepG2 cells. | 2020 | Details |
| A07890 | 32321679 | Obes Res Clin Pract | Increased BMI 'alone' does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results. | 2020 | Details |
| A07892 | 32319718 | J Intern Med | Prevalence, characteristics and mortality outcomes of obese, nonobese and lean NAFLD in the United States, 1999-2016. | 2020 | Details |
| A07893 | 32319693 | Hepatology | Epidemiology of Hepatocellular Carcinoma. | 2020 | Details |
| A07894 | 32318847 | Eur Radiol | Prospective comparison of longitudinal change in hepatic proton density fat fraction (PDFF) estimated by magnitude-based MRI (MRI-M) and complex-based MRI (MRI-C). | 2020 | Details |
| A07898 | 32317687 | Sci Rep | Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07900 | 32317584 | Eur J Gastroenterol Hepatol | De-novo nonalcoholic fatty liver disease at 5 years after liver transplantation: prevalence and predictive factors. | 2021 | Details |
| A07902 | 32316984 | BMC Health Serv Res | Protocol for a randomised trial testing a community fibrosis assessment service for patients with suspected non-alcoholic fatty liver disease: LOCal assessment and triage evaluation of non-alcoholic fatty liver disease (LOCATE-NAFLD). | 2020 | Details |
| A07906 | 32315893 | Nutr Res | Siphonaxanthin, a carotenoid from green algae Codium cylindricum, protects Ob/Ob mice fed on a high-fat diet against lipotoxicity by ameliorating somatic stresses and restoring anti-oxidative capacity. | 2020 | Details |