Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A07321 | 32540177 | J Hepatol | Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis. | 2020 | Details |
A07323 | 32537840 | Hepatol Res | Modelling the economic and clinical burden of non-alcoholic steatohepatitis in East Asia: Data from Hong Kong. | 2020 | Details |
A07325 | 32536770 | World J Gastroenterol | Metabolic inflammation as an instigator of fibrosis during non-alcoholic fatty liver disease. | 2020 | Details |
A07329 | 32534989 | Chem Biol Interact | Roles of peroxisome proliferator-activated receptor α in the pathogenesis of ethanol-induced liver disease. | 2020 | Details |
A07330 | 32534588 | Cardiovasc Diabetol | Non-alcoholic steatohepatitis and progression of carotid atherosclerosis in patients with type 2 diabetes: a Korean cohort study. | 2020 | Details |
A07333 | 32533233 | Pathologe | [Histopathological diagnosis and differential diagnosis of nonalcoholic fatty liver disease]. | 2020 | Details |
A07338 | 32531442 | Ann Diagn Pathol | Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD. | 2020 | Details |
A07342 | 32531295 | Metabolism | Changing trends of liver transplantation and mortality from non-alcoholic fatty liver disease. | 2020 | Details |
A07344 | 32530991 | J Gastrointestin Liver Dis | Identification of Patients with Advanced Fibrosis Due to Nonalcoholic Fatty Liver Disease: Considerations for Best Practice. | 2020 | Details |
A07350 | 32529354 | Obes Surg | Correlation between Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease before and after Metabolic Bariatric Surgery. | 2020 | Details |
A07358 | 32526788 | Semin Liver Dis | The NLRP3 Inflammasome in Alcoholic and Nonalcoholic Steatohepatitis. | 2020 | Details |
A07360 | 32526784 | Semin Liver Dis | Noninvasive Tests in the Assessment of NASH and NAFLD Fibrosis: Now and Into the Future. | 2020 | Details |
A07361 | 32526482 | Cell Mol Gastroenterol Hepatol | Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems. | 2020 | Details |
A07365 | 32524859 | Expert Opin Drug Discov | How effective are nonalcoholic fatty liver disease models for drug discovery? | 2020 | Details |
A07368 | 32524096 | Hawaii J Health Soc Welf | Nonalcoholic Fatty Liver Disease: An Important Consideration for Primary Care Providers in Hawai'i. | 2020 | Details |
A07370 | 32523627 | Therap Adv Gastroenterol | Plasma eicosanoids as noninvasive biomarkers of liver fibrosis in patients with nonalcoholic steatohepatitis. | 2020 | Details |
A07371 | 32523319 | World J Gastroenterol | Association between non-alcoholic fatty liver disease and obstructive sleep apnea. | 2020 | Details |
A07373 | 32523101 | Sci Rep | Prediction of advanced fibrosis in non-alcoholic fatty liver disease using gut microbiota-based approaches compared with simple non-invasive tools. | 2020 | Details |
A07377 | 32521615 | Cancers (Basel) | Hepatocellular Carcinoma Emergence in Diabetic Mice with Non-Alcoholic Steatohepatitis Depends on Diet and Is Delayed in Liver Exhibiting an Active Immune Response. | 2020 | Details |
A07379 | 32520458 | Rev Med Suisse | [NASH: a less known but severe complication of diabetes]. | 2020 | Details |
A07383 | 32518675 | Clin Diabetes Endocrinol | Nonalcoholic fatty liver disease and type 2 diabetes: where do Diabetologists stand? | 2020 | Details |
A07384 | 32518428 | Clin Biochem Rev | Serum Marker Panels for Predicting Liver Fibrosis - An Update. | 2020 | Details |
A07385 | 32518275 | Sci Rep | The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07388 | 32518095 | CMAJ Open | Burden of nonalcoholic fatty liver disease in Canada, 2019-2030: a modelling study. | 2020 | Details |
A07390 | 32516937 | Int J Mol Sci | Elastography Techniques for the Assessment of Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
A07392 | 32516028 | Am J Physiol Endocrinol Metab | NOD2 in hepatocytes engages a liver-gut axis to protect against steatosis, fibrosis, and gut dysbiosis during fatty liver disease in mice. | 2020 | Details |
A07394 | 32515880 | Liver Int | Mechanisms for increased risk of diabetes in chronic liver diseases. | 2020 | Details |
A07395 | 32515534 | Hepatol Res | Validation of albumin, bilirubin, and platelet criteria for avoiding screening endoscopy in patients with advanced fibrosis. | 2020 | Details |
A07397 | 32514497 | JHEP Rep | Combined alcoholic and non-alcoholic steatohepatitis. | 2020 | Details |
A07398 | 32514465 | JGH Open | No association between binge eating disorder and severity of non-alcoholic fatty liver disease in severely obese patients. | 2020 | Details |
A07399 | 32514460 | JGH Open | Discordant pathological diagnosis of non-alcoholic fatty liver disease: A prospective multicenter study. | 2019 | Details |
A07402 | 32514444 | JGH Open | Thyroid-stimulating hormone is an independent risk factor of non-alcoholic fatty liver disease. | 2019 | Details |
A07408 | 32512581 | PLoS One | Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet. | 2020 | Details |
A07409 | 32512191 | Biochim Biophys Acta Mol Basis Dis | Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells. | 2020 | Details |
A07410 | 32512072 | Toxicol Appl Pharmacol | Diosmin ameliorates inflammation, insulin resistance, and fibrosis in an experimental model of non-alcoholic steatohepatitis in rats. | 2020 | Details |
A07414 | 32509277 | F1000Res | Recent advances in understanding and managing pediatric nonalcoholic fatty liver disease. | 2020 | Details |
A07427 | 32504663 | J Hepatol | Diverse effects of hepatic steatosis on fibrosis progression and functional cure in virologically quiescent chronic hepatitis B. | 2020 | Details |
A07429 | 32502647 | Biochim Biophys Acta Mol Basis Dis | The role of AMPKα2 in the HFD-induced nonalcoholic steatohepatitis. | 2020 | Details |
A07431 | 32502037 | Medicine (Baltimore) | Accuracy of FibroScan in analysis of liver fibrosis in patients with concomitant chronic Hepatitis B and nonalcoholic fatty liver disease. | 2020 | Details |
A07433 | 32499209 | J Formos Med Assoc | Pathologic findings of patients with nonalcoholic fatty liver disease and the impact of concurrent hepatitis B virus infection in Taiwan. | 2020 | Details |
A07443 | 32494762 | Curr Dev Nutr | Targeted Nutrient Modifications in Purified Diets Differentially Affect Nonalcoholic Fatty Liver Disease and Metabolic Disease Development in Rodent Models. | 2020 | Details |
A07447 | 32492133 | J Biochem | Arachidonate 12S-lipoxygenase of platelet-type in hepatic stellate cells of methionine and choline-deficient diet-fed mice. | 2020 | Details |
A07448 | 32492075 | PLoS One | Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. | 2020 | Details |
A07449 | 32491288 | Physiol Int | Betanin effect on PPAR-α and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis. | 2020 | Details |
A07450 | 32490903 | Arq Gastroenterol | PANCREATIC STEATOSIS: A NEW DIAGNOSIS AND THERAPEUTIC CHALLENGE IN GASTROENTEROLOGY. | 2020 | Details |
A07461 | 32486073 | Cancers (Basel) | Exercise Attenuates the Transition from Fatty Liver to Steatohepatitis and Reduces Tumor Formation in Mice. | 2020 | Details |
A07462 | 32485838 | Int J Mol Sci | The Role of Insulin Resistance and Diabetes in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07479 | 32478487 | Liver Int | Comparison of MAFLD and NAFLD diagnostic criteria in real world. | 2020 | Details |
A07480 | 32478287 | Nat Metab | Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. | 2020 | Details |
A07481 | 32477116 | Front Pharmacol | Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application. | 2020 | Details |
A07484 | 32476802 | World J Gastroenterol | Gamma-glutamyl transferase and cardiovascular risk in nonalcoholic fatty liver disease: The Gut and Obesity Asia initiative. | 2020 | Details |
A07488 | 32476514 | Scand J Gastroenterol | Biopsy rate and nonalcoholic steatohepatitis (NASH) in patients with nonalcoholic fatty liver disease (NAFLD). | 2020 | Details |
A07493 | 32475638 | Biochem Biophys Res Commun | Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice. | 2020 | Details |
A07497 | 32472598 | FASEB J | Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr-/- .Leiden mice. | 2020 | Details |
A07504 | 32469428 | Diabetes Metab Res Rev | Adipose tissue remodelling in obese subjects is a determinant of presence and severity of fatty liver disease. | 2020 | Details |
A07506 | 32467498 | Am J Ther | How to Reduce Cardiovascular Risk in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07507 | 32466319 | Int J Mol Sci | Liquid Biopsy for the Diagnosis of Viral Hepatitis, Fatty Liver Steatosis, and Alcoholic Liver Diseases. | 2020 | Details |
A07510 | 32463484 | Hepatology | Protective and Detrimental Roles of p38α Mitogen-Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07512 | 32461992 | Biomed Res Int | Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis. | 2020 | Details |
A07514 | 32461397 | Indian J Med Res | Fibroscan as a non-invasive predictor of hepatic steatosis in women with polycystic ovary syndrome. | 2020 | Details |
A07518 | 32460476 | J Pathol Transl Med | A scoring system for the diagnosis of non-alcoholic steatohepatitis from liver biopsy. | 2020 | Details |
A07519 | 32460399 | Liver Int | Genetic variants in the MTHFR are not associated with fatty liver disease. | 2020 | Details |
A07523 | 32457304 | Sci Rep | A Gilbert syndrome-associated haplotype protects against fatty liver disease in humanized transgenic mice. | 2020 | Details |
A07526 | 32455155 | Regen Ther | Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles. | 2020 | Details |
A07532 | 32454036 | Gastroenterology | ADH1B∗2 Is Associated With Reduced Severity of Nonalcoholic Fatty Liver Disease in Adults, Independent of Alcohol Consumption. | 2020 | Details |
A07535 | 32451920 | Obes Surg | Elastic Fibers Density: a New Parameter of Improvement of NAFLD in Bariatric Surgery Patients. | 2020 | Details |
A07536 | 32451628 | J Gastroenterol | Confounding factors of non-invasive tests for nonalcoholic fatty liver disease. | 2020 | Details |
A07537 | 32451205 | Ann Hepatol | Is there an association between commonly employed biomarkers of liver fibrosis and liver stiffness in the general population? | 2020 | Details |
A07540 | 32450460 | Prostaglandins Leukot Essent Fatty Acids | Omega-3 derivatives, specialized pro-resolving mediators: Promising therapeutic tools for the treatment of pain in chronic liver disease. | 2020 | Details |
A07541 | 32450363 | Clin Gastroenterol Hepatol | Accuracy of Two-Dimensional Shear Wave Elastography and Attenuation Imaging for Evaluation of Patients With Nonalcoholic Steatohepatitis. | 2020 | Details |
A07542 | 32450149 | Gastroenterology | Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122. | 2020 | Details |
A07543 | 32448832 | Intern Med | SGLT2 Inhibitor Treatment Outcome in Nonalcoholic Fatty Liver Disease Complicated with Diabetes Mellitus: The Long-term Effects on Clinical Features and Liver Histopathology. | 2020 | Details |
A07547 | 32447878 | Clin Mol Hepatol | Clinical application of ultrasonography-guided percutaneous liver biopsy and its safety over 18 years. | 2020 | Details |
A07548 | 32446270 | Br J Pharmacol | Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway. | 2020 | Details |
A07549 | 32446022 | Semin Arthritis Rheum | Safety of TNF inhibitors in rheumatic disease in case of NAFLD and cirrhosis. | 2020 | Details |
A07565 | 32442221 | PLoS One | Expression of hepatic stellate cell activation-related genes in HBV-, HCV-, and nonalcoholic fatty liver disease-associated fibrosis. | 2020 | Details |
A07573 | 32439605 | Drug Discov Today | Long noncoding RNAs in nonalcoholic fatty liver disease and liver fibrosis: state-of-the-art and perspectives in diagnosis and treatment. | 2020 | Details |
A07575 | 32438959 | Biomed Environ Sci | Peripheral Artery Disease and Risk of Fibrosis Deterioration in Nonalcoholic Fatty Liver Disease: A Prospective Investigation. | 2020 | Details |
A07580 | 32436818 | Curr Pharm Des | The Relevance of Noninvasive Tools To Assess Fibrosis in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
A07582 | 32436128 | High Blood Press Cardiovasc Prev | Evaluation of Cardiovascular Risk in Patient with Primary Non-alcoholic Fatty Liver Disease. | 2020 | Details |
A07586 | 32434740 | Transplant Proc | The Utility of Assessing Liver Allograft Fibrosis and Steatosis Post-Liver Transplantation Using Transient Elastography With Controlled Attenuation Parameter. | 2020 | Details |
A07588 | 32434697 | Transl Res | Cathepsin B deficiency ameliorates liver lipid deposition, inflammatory cell infiltration, and fibrosis after diet-induced nonalcoholic steatohepatitis. | 2020 | Details |
A07589 | 32433419 | Eur J Gastroenterol Hepatol | Low real-world eligibility rates for nonalcoholic steatohepatitis patients for phase 3 clinical trial criteria application in a large academic health system. | 2021 | Details |
A07591 | 32432142 | World J Clin Cases | Cholesteryl ester storage disease of clinical and genetic characterisation: A case report and review of literature. | 2020 | Details |
A07595 | 32431115 | Diabetes Metab J | Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Position Statement of the Fatty Liver Research Group of the Korean Diabetes Association. | 2020 | Details |
A07598 | 32429653 | Pol J Pathol | Role of mast cells in the pathogenesis of liver fibrosis in nonalcoholic fatty liver disease. | 2020 | Details |
A07599 | 32429590 | Nutrients | Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance. | 2020 | Details |
A07603 | 32427918 | Sci Rep | Hepatic steatosis among people living with HIV in Southern Brazil: prevalence and risk factors. | 2020 | Details |
A07609 | 32424494 | Adv Exp Med Biol | Non-alcoholic Fatty Liver Disease and Diabetes Mellitus. | 2021 | Details |
A07614 | 32420347 | Biomed Res Int | The Prevalence of NAFLD and Fibrosis in Bariatric Surgery Patients and the Reliability of Noninvasive Diagnostic Methods. | 2020 | Details |
A07620 | 32417373 | Life Sci | CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease. | 2020 | Details |
A07625 | 32416645 | Hepatology | Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. | 2020 | Details |
A07627 | 32414883 | CMAJ Open | Risk stratification of patients with nonalcoholic fatty liver disease using a case identification pathway in primary care: a cross-sectional study. | 2020 | Details |
A07629 | 32414752 | BMJ Open Gastroenterol | Spatial expression of glucagon-like peptide 1 receptor and caveolin-1 in hepatocytes with macrovesicular steatosis in non-alcoholic steatohepatitis. | 2020 | Details |
A07633 | 32413995 | Genes (Basel) | Expression of the Long Noncoding RNA GAS5 Correlates with Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A07634 | 32413869 | Aging (Albany NY) | Overexpression of miR-142-5p inhibits the progression of nonalcoholic steatohepatitis by targeting TSLP and inhibiting JAK-STAT signaling pathway. | 2020 | Details |
A07636 | 32413340 | Lancet Gastroenterol Hepatol | Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis. | 2020 | Details |
A07645 | 32410320 | Hepatol Res | Allele HLA-DQB1*06 reduces fibrosis score in patients with non-alcoholic fatty liver disease. | 2020 | Details |
A07648 | 32409850 | Internist (Berl) | [New pharmacological treatment options for nonalcoholic fatty liver disease]. | 2020 | Details |
A07657 | 32407146 | Arch Physiol Biochem | trans-Chalcone inhibits transforming growth factor-β1 and connective tissue growth factor-dependent collagen expression in the heart of high-fat diet-fed rats. | 2020 | Details |