Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23541 | 23697659 | Antioxid Redox Signal | A novel antihypoglycemic role of inducible nitric oxide synthase in liver inflammatory response induced by dietary cholesterol and endotoxemia. | 2013 | Details |
| A23542 | 23696823 | PLoS One | Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis. | 2013 | Details |
| A23547 | 23692125 | Free Radic Res | A high-fat and cholesterol diet causes fatty liver in guinea pigs. The role of iron and oxidative damage. | 2013 | Details |
| A23549 | 23691267 | Oxid Med Cell Longev | Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease. | 2013 | Details |
| A23564 | 23671720 | World J Hepatol | Melatonin attenuates high fat diet-induced fatty liver disease in rats. | 2013 | Details |
| A23584 | 23656726 | Br J Nutr | Effects of long-term administration of saturated and n-3 fatty acid-rich diets on lipid utilisation and oxidative stress in rat liver and muscle tissues. | 2013 | Details |
| A23591 | 23652610 | Curr Opin Organ Transplant | Evolving aspects of liver transplantation for nonalcoholic steatohepatitis. | 2013 | Details |
| A23596 | 23647015 | Br J Pharmacol | Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. | 2013 | Details |
| A23597 | 23643483 | Toxicol Lett | Interactive effects of smoking and glutathione S-transferase polymorphisms on the development of non-alcoholic fatty liver disease. | 2013 | Details |
| A23603 | 23634883 | Lipids Health Dis | Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. | 2013 | Details |
| A23607 | 23630437 | Int J Med Sci | Status of essential trace minerals and oxidative stress in viral hepatitis C patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A23612 | 27904876 | Postdoc J | The Mediation of Hepatic Lipogenesis Through Estrogens. | 2013 | Details |
| A23629 | 23616151 | J Clin Endocrinol Metab | Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease. | 2013 | Details |
| A23633 | 23611112 | Clin Exp Pharmacol Physiol | A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. | 2013 | Details |
| A23638 | 23607264 | Hepatol Res | Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study. | 2013 | Details |
| A23659 | 23592516 | Mol Pharmacol | Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. | 2013 | Details |
| A23681 | 23567086 | J Hepatol | Decoding cell death signals in liver inflammation. | 2013 | Details |
| A23695 | 23558563 | Dig Dis Sci | Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes. | 2013 | Details |
| A23696 | 23558065 | Hepatobiliary Pancreat Dis Int | Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges. | 2013 | Details |
| A23721 | 23537653 | Biochem Biophys Res Commun | Hydrogen peroxide impairs autophagic flux in a cell model of nonalcoholic fatty liver disease. | 2013 | Details |
| A23730 | 23528177 | Annu Rev Nutr | Fatty acid-regulated transcription factors in the liver. | 2013 | Details |
| A23737 | 23518490 | J Pediatr Gastroenterol Nutr | Serum bilirubin level is inversely associated with nonalcoholic steatohepatitis in children. | 2013 | Details |
| A23742 | 23516172 | World J Gastrointest Pharmacol Ther | Inhibition of apoptosis in the management of nonalcoholic fatty liver disease. | 2013 | Details |
| A23743 | 23515587 | Eur J Nutr | Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. | 2013 | Details |
| A23746 | 23512965 | Obesity (Silver Spring) | Metabolomic signatures in lipid-loaded HepaRGs reveal pathways involved in steatotic progression. | 2013 | Details |
| A23757 | 23508103 | Mol Cell Biol | Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3. | 2013 | Details |
| A23761 | 23505022 | Proteomics | Proteomic profile of carbonylated proteins in rat liver: exercise attenuated oxidative stress may be involved in fatty liver improvement. | 2013 | Details |
| A23783 | 23483818 | World J Gastroenterol | From fatty liver to fibrosis: a tale of "second hit". | 2013 | Details |
| A23785 | 23482433 | Korean J Pediatr | Noninvasive diagnosis of pediatric nonalcoholic fatty liver disease. | 2013 | Details |
| A23795 | 23477499 | Antioxid Redox Signal | Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model. | 2013 | Details |
| A23797 | 23475581 | Curr Diab Rep | Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis. | 2013 | Details |
| A23827 | 25755466 | J Clin Exp Hepatol | Patients with Nonalcoholic Fatty Liver Disease (NAFLD) have Higher Oxidative Stress in Comparison to Chronic Viral Hepatitis. | 2012 | Details |
| A23856 | 23425054 | J Gastroenterol Hepatol | Unconjugated bilirubin, a potent endogenous antioxidant, is decreased in patients with non-alcoholic steatohepatitis and advanced fibrosis. | 2013 | Details |
| A23886 | 23402636 | J Med Food | Health benefits of blue-green algae: prevention of cardiovascular disease and nonalcoholic fatty liver disease. | 2013 | Details |
| A23903 | 23394097 | Curr Pharm Des | Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment. | 2013 | Details |
| A23906 | 23394094 | Curr Pharm Des | Antioxidant therapy and drugs interfering with lipid metabolism: could they be effective in NAFLD patients? | 2013 | Details |
| A23908 | 23394092 | Curr Pharm Des | Pathophysiology of NASH: perspectives for a targeted treatment. | 2013 | Details |
| A23916 | 23390892 | Atherosclerosis | Sex-influenced association of nonalcoholic fatty liver disease with coronary heart disease. | 2013 | Details |
| A23943 | 23367495 | J Clin Res Pediatr Endocrinol | Association between insulin resistance and oxidative stress parameters in obese adolescents with non-alcoholic fatty liver disease. | 2013 | Details |
| A23945 | 23363254 | Endocr Regul | Association of nonalcoholic fatty liver disease (NAFLD) with urolithiasis. | 2013 | Details |
| A23962 | 23348005 | Toxicol In Vitro | Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. | 2013 | Details |
| A23963 | 23347840 | Clin Res Hepatol Gastroenterol | Non-alcoholic steatohepatitis in morbidly obese patients. | 2013 | Details |
| A23967 | 23346097 | Front Genet | Molecular Interactions between NAFLD and Xenobiotic Metabolism. | 2013 | Details |
| A23976 | 23331460 | Basic Clin Pharmacol Toxicol | Quercetin decreases liver damage in mice with non-alcoholic steatohepatitis. | 2013 | Details |
| A23980 | 23329365 | J Gastroenterol | Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma. | 2013 | Details |
| A23982 | 23329013 | Dig Dis Sci | Fat mass and obesity-associated gene enhances oxidative stress and lipogenesis in nonalcoholic fatty liver disease. | 2013 | Details |
| A23987 | 23325576 | Hepatology | Hepatic reticuloendothelial system cell iron deposition is associated with increased apoptosis in nonalcoholic fatty liver disease. | 2013 | Details |
| A23994 | 23320150 | J Obes | Nonalcoholic fatty liver disease and cardiovascular disease: has the time come for cardiologists to be hepatologists? | 2012 | Details |
| A24000 | 23315648 | Z Gastroenterol | Non-alcoholic steatohepatitis occurs in celiac disease and is associated with cellular stress. | 2013 | Details |
| A24011 | 23303872 | J Nutr | Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis. | 2013 | Details |
| A24012 | 23303639 | Biofactors | Curcumin and liver disease. | 2013 | Details |
| A24017 | 23299992 | Hepatology | Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease. | 2013 | Details |
| A24046 | 23285030 | PLoS One | Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice. | 2012 | Details |
| A24058 | 31528500 | J Carcinog Mutagen | Exocycilic DNA Adducts in a Murine Model of Non-alcoholic Steatohepatitis. | 2013 | Details |
| A24060 | 25674420 | Springerplus | (-)-Epigallocatechin-3-gallate suppresses hepatic preneoplastic lesions developed in a novel rat model of non-alcoholic steatohepatitis. | 2013 | Details |
| A24070 | 23268566 | Scand J Gastroenterol | The role of Kupffer cells in the morphogenesis of nonalcoholic steatohepatitis - ultrastructural findings. The first report in pediatric patients. | 2012 | Details |
| A24072 | 23266468 | Diabetes Metab | Non-alcoholic fatty liver disease and insulin resistance: from bench to bedside. | 2012 | Details |
| A24087 | 23238106 | J Hepatol | A 360-degree overview of paediatric NAFLD: recent insights. | 2012 | Details |
| A24122 | 23211317 | J Hepatol | Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24124 | 23207144 | J Hepatol | Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis. | 2012 | Details |
| A24126 | 23205728 | Free Radic Res | Improved oxidative stress and cardio-metabolic status in obese prepubertal children with liver steatosis treated with lifestyle combined with Vitamin E. | 2013 | Details |
| A24127 | 23203768 | Mol Nutr Food Res | Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways. | 2012 | Details |
| A24135 | 25755455 | J Clin Exp Hepatol | A Randomized Controlled Trial Comparing Efficacy of Pentoxifylline and Pioglitazone on Metabolic Factors and Liver Histology in Patients with Non-alcoholic Steatohepatitis. | 2012 | Details |
| A24148 | 23178552 | Prog Lipid Res | Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease. | 2012 | Details |
| A24155 | 23174676 | Acta Biochim Biophys Sin (Shanghai) | Antioxidant effect of apolipoprotein A-I on high-fat diet-induced non-alcoholic fatty liver disease in rabbits. | 2012 | Details |
| A24165 | 23159641 | Life Sci | Nonalcoholic fatty liver disease: current and potential therapies. | 2012 | Details |
| A24172 | 23154483 | J Pediatr Gastroenterol Nutr | Levels of serum ceruloplasmin associate with pediatric nonalcoholic fatty liver disease. | 2013 | Details |
| A24178 | 23144979 | PLoS One | The A736V TMPRSS6 polymorphism influences hepatic iron overload in nonalcoholic fatty liver disease. | 2012 | Details |
| A24206 | 23123503 | Biochimie | Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. | 2012 | Details |
| A24227 | 23092327 | Curr Pharm Des | Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD). | 2013 | Details |
| A24232 | 23073870 | Intern Emerg Med | Non-alcoholic fatty liver disease and cardiovascular disease: epidemiological, clinical and pathophysiological evidences. | 2012 | Details |
| A24239 | 23087670 | Front Neurol | Obstructive sleep apnea and non-alcoholic Fatty liver disease: is the liver another target? | 2012 | Details |
| A24250 | 23075940 | Curr Opin Clin Nutr Metab Care | Vitamin E and nonalcoholic fatty liver disease. | 2012 | Details |
| A24276 | 23055155 | Hepatology | Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH. | 2013 | Details |
| A24309 | 24683373 | Gastroenterol Hepatol (N Y) | Noninvasive Diagnosis of NASH and Liver Fibrosis Within the Spectrum of NAFLD. | 2012 | Details |
| A24311 | 23014486 | J Nutr | Opuntia ficus indica (nopal) attenuates hepatic steatosis and oxidative stress in obese Zucker (fa/fa) rats. | 2012 | Details |
| A24317 | 23002334 | World J Gastroenterol | Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis. | 2012 | Details |
| A24326 | 22997724 | Klin Med (Mosk) | [Pathogenetic therapy of metabolic syndrome at the stage of visceral lesions]. | 2012 | Details |
| A24331 | 22991207 | Physiol Genomics | Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition. | 2012 | Details |
| A24350 | 22978392 | Curr Drug Metab | Fatty acids - induced lipotoxicity and inflammation. | 2012 | Details |
| A24373 | 22961556 | Hepatology | Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease. | 2012 | Details |
| A24374 | 22960889 | Indian J Med Res | Association of pro-inflammatory cytokines, adipokines & oxidative stress with insulin resistance & non-alcoholic fatty liver disease. | 2012 | Details |
| A24375 | 22960565 | J Proteomics | Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin. | 2012 | Details |
| A24389 | 22942630 | Int J Angiol | Carotid intima-media thickness and liver histology in hemodialysis patients with nonalcoholic Fatty liver disease. | 2011 | Details |
| A24393 | 22940046 | J Hepatol | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. | 2012 | Details |
| A24396 | 22939811 | Eur J Intern Med | Reduced heme oxygenase-1 expression in steatotic livers infected with hepatitis C virus. | 2012 | Details |
| A24402 | 22934006 | Front Physiol | Liver fibrogenesis in non-alcoholic steatohepatitis. | 2012 | Details |
| A24420 | 22915297 | J Nutr | Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis. | 2012 | Details |
| A24423 | 22913202 | Eur Rev Med Pharmacol Sci | Glycine alleviates liver injury induced by deficiency in methionine and or choline in rats. | 2012 | Details |
| A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
| A24427 | 22906265 | J Int Med Res | Levels of the oxidative stress marker γ-glutamyltranspeptidase at different stages of nonalcoholic fatty liver disease. | 2012 | Details |
| A24433 | 22899411 | Georgian Med News | Some aspects of pathogenesis of nonalcoholic fatty liver disease in postmenopausal women. | 2012 | Details |
| A24434 | 22899407 | Georgian Med News | [Treatment of nonalcogolic fatty disease of liver]. | 2012 | Details |
| A24438 | 22893453 | Endocr J | Fatty liver as a consequence and cause of insulin resistance: lessons from type 2 diabetic liver. | 2012 | Details |
| A24452 | 22878918 | Dig Dis Sci | Probucol ameliorates the development of nonalcoholic steatohepatitis in rats fed high-fat diets. | 2012 | Details |
| A24462 | 22872676 | FASEB J | Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism. | 2012 | Details |
| A24463 | 22871994 | Clin Pharmacol Ther | Nrf2: a potential target for new therapeutics in liver disease. | 2012 | Details |
| A24468 | 22864747 | Arch Pharm Res | Protective effects of gypenosides against fatty liver disease induced by high fat and cholesterol diet and alcohol in rats. | 2012 | Details |
| A24469 | 22864348 | Yakugaku Zasshi | [Retinoids as promising treatment for non-alcoholic fatty liver disease]. | 2012 | Details |
| A24472 | 22863080 | Liver Int | α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. | 2012 | Details |